Immunologic asthma occupational. Medical search. Frequent questions

Occupational lung diseases refers to the development of lung diseases from inhalational exposure that occurs at the work place. (medscape.com)
Occupational lung disease can result from inhalational exposure to minerals and dusts, microbes, animal and insect proteins, and chemicals and can have long-lasting effects even after the exposure ceases. (medscape.com)
Nanoparticles like zinc oxide are widely used in sunscreens, paints, textiles, and other products and can lead to accidental occupational inhalational exposure. (medscape.com)
Few occupational exposure limits exist specifically for nanomaterials and certain nanoparticles may be more hazardous than larger particles of the same substance. (medscape.com)
Therefore, existing occupational exposure limits for a substance may not provide adequate protection from nanoparticles of that substance. (medscape.com)
Exposure and immunological determinants in a murine model for toluene diisocyanate (TDI) asthma. (cdc.gov)
Isocyanate -induced asthma, the most commonly reported cause of occupational asthma, has been difficult to diagnose and control, in part, because the biological mechanisms responsible for the disease and the determinants of exposure have been difficult to define. (cdc.gov)
To determine the impact of exposure dose as well as the involvement of immune (allergic) or nonimmune mechanisms, a murine model of TDI asthma was established and characterized following either low-level subchronic or high-dose acute inhalation TDI exposure. (cdc.gov)
In contrast, mice that received acute TDI exposure demonstrated increased AHR, specific IgG antibodies, and pathology in the lung consistent with asthma, but without the presence of elevated serum IgE, lung eosionophilia, or increased expression of T(H) cytokines. (cdc.gov)
These results describe mouse models for TDI asthma consistent with that found in workers with occupational asthma and indicate that the pulmonary pathology associated with TDI can vary depending upon the exposure paradigm. (cdc.gov)
Excess asthma risk was associated with high exposure to biological dusts, mineral dusts, and gases and fumes. (bmj.com)
Exposure to many environmental factors can trigger and exacerbate asthma. (cdc.gov)
Medical and nursing education programs often do not fully incorporate environmental questions and an exposure history into asthma management. (cdc.gov)
In children and adults, sensitive to indoor allergens, the severity of asthma symptoms may vary with the level of exposure. (cdc.gov)
Taken together, these studies make a strong argument for the importance of allergen and irritant exposure as aggravating factors in asthma in both children and adults. (cdc.gov)
Occupational asthma is new onset asthma or the recurrence of previously quiescent asthma directly caused by exposure to an agent at workplace. (wikipedia.org)
Irritant-induced (occupational) asthma is a non-immunologic form of asthma that results from a single or multiple high dose exposure to irritant products. (wikipedia.org)
Unlike those with sensitizer-induced occupational asthma, subjects with irritant-induced occupational asthma do not develop work-related asthma symptoms after re-exposure to low concentrations of the irritant that initiated the symptoms. (wikipedia.org)
Symptoms may develop over many years as in sensitizer induced asthma or may occur after a single exposure to a high-concentration agent as in case of RADS. (wikipedia.org)
Like compounds from biological sources and low-molecular-weight nonoccupational asthma, occupational asthma is probably the chemicals cause occupational asthma after a latent period of result of multiple genetic, environmental, and behavioral exposure. (cdc.gov)
Environmental factors that can detect specific IgE antibodies against most low-molecular- affect the initiation of occupational asthma include the intrinsic weight agents has resulted in a search for alternative or characteristics of causative agents as well as the influence of the complementary physiopathologic mechanisms leading to airway level and route of exposure at the workplace. (cdc.gov)
In contrast, the mechanism of the type of occupational asthma that occurs without latency after high-level exposure to irritants remains undetermined. (cdc.gov)
Exposure to laboratory animals often causes the appearance of immunologic sensitization and symptoms. (occupationalasthma.com)
Our aim was to determine the incidence of occupational rhinoconjunctivitis and the timing of symptoms and their determinants in apprentices starting exposure to laboratory animals. (occupationalasthma.com)
The incidence of occupational rhinoconjunctivitis symptoms with or without immunologic sensitization is high in apprentices starting exposure to laboratory animals. (occupationalasthma.com)
These same chemicals can also damage the respiratory tract, causing chronic respiratory disease, and asthma, and some studies have found an association between exposure to some wood dusts and oral cancers. (reptilestar.com)
Exposure to plicatic acid can cause or exacerbate asthma, rhinitis or conjunctivitis in humans and in animals, and the damage can be progressive. (reptilestar.com)
Following exposure to red cedar or plicatic acid, a person with occupational asthma may have either an immediate, or a delayed reaction, or both (Malo 1989). (reptilestar.com)
The objective of this study is to use a community-engaged approach to characterize individual, occupational, and neighborhood-level factors that influence personal air VOC exposure among this overburdened group of Hispanic women in San Antonio, Texas, and to explore associations between these exposures with biomarkers of inflammation and oxidative stress. (uth.edu)
Occupational exposure to PC is underestimated in outdoor workers and especially in forestry workers (FW) and is globally diffusing because of rising temperatures. (biomedcentral.com)
This is the first report of hypersensitivity reactions in SI FW due to occupational exposure to PC. (biomedcentral.com)
Further screenings not only in FW but also in other populations of outdoor workers are needed in order to assess the real incidence of contact and airborne reactions due to occupational exposure to PC. (biomedcentral.com)
Occupational exposure to PC has been reported even if in forestry workers (FW) it is underestimated. (biomedcentral.com)
During the annual scheduled examination of a population of 630 FW in the Mountains of north-eastern Sicily, the occupational health physician asked the workers to report if they had ever experienced a reaction after exposure to PC. (biomedcentral.com)
Our multi-investigator laboratory is interested in the natural history, immunologic mechanisms, and genetic and exposure risks associated with sarcoidosis, chronic beryllium disease, and other granulomatous and occupational lung diseases such as hypersensitivity pneumonitis. (nationaljewish.org)
Asthma, runny nose, and itchy eyes may occur with mucus membrane exposure. (rdhmag.com)
3. ACD has never been reported where there has been extensive occupational enzyme exposure in the detergent enzyme industries which, in the past, has led to respiratory sensitization and/or irritant dermatitis. (europa.eu)
The present study provides in vivo evidence that a GSH mediated pathway underlies asthma-like eosinophilic inflammatory responses to respiratory tract isocyanate exposure. (cdc.gov)
In North Carolina, a reported increase in persons presenting with asthma symptoms was postulated to be caused by exposure to mold ( 2 ). (cdc.gov)
Exposure, particularly occupational exposure, to these organisms may lead to the development of respiratory or contact allergies. (biomedcentral.com)
Exposure assessment in cohort studies of childhood asthma. (creod.on.ca)
OBJECTIVE: The purpose of this paper is to summarize and discuss issues that make accurate exposure assessment a challenge and to suggest strategies for improving exposure assessment in longitudinal cohort studies of childhood asthma and allergies. (creod.on.ca)
Home › Occupational Lung Disease › Exposure assessment in cohort studies of childhood asthma. (creod.on.ca)
Asthma and allergic rhinitis are the two conditions that are most frequently linked to mold exposure. (majorrs.com)
Effects of Lifetime Occupational Pesticide Exposure on Postural Control Among Farmworkers and Non-Farmworkers. (wakehealth.edu)

In most cases, occupational exposures induce new onset asthma in a healthy subject, or workplace exposures may reactivate asthma in individuals who have been asymptomatic for years, or may aggravate pre-existing asthma. (bmj.com)
In each case, identifying which of these possibilities is true (that is, work related exposures as asthma inducers or asthma triggers) is relevant for the management of the disease, including prevention of additional cases, treatment, disability evaluation, and compensation. (bmj.com)
Under reporting of occupational asthma may be more common among women, since the risk of asthma attributable to occupational exposures among women was higher than expected. (bmj.com)
Describe the impact of occupational exposures on adult asthma prevalence. (cdc.gov)
WEA is present in about a fifth of patients with asthma and a wide variety of conditions at work, including irritant chemicals, dusts, second-hand smoke, common allergens that may be present at work, as well as other "exposures" such as emotional stress, worksite temperature, and physical exertion can exacerbate asthma symptoms in these patients. (wikipedia.org)
Several other airway diseases caused by inhalational workplace exposures can be distinguished from occupational and occupationally aggravated asthma. (msdmanuals.com)
Across these independent studies, shared risk factors for RA and airway disease were determined to include older age, cigarette smoking, lower socioeconomic status, infections and microbial dysbiosis, occupational exposures and air pollutants, and poor nutrition [6, 7]. (nih.gov)
However, of these shared risk factors, only older age, cigarette smoking, and occupational exposures have been specifically investigated as risk factors for airway disease among patients with RA. (nih.gov)
Asthma in Texas Healthcare Workers II is a CDC-NIOSH funded R01 research project to study associations between occupational exposures and asthma among healthcare workers (HCWs), and to assess its burden in this worker population. (uth.edu)
Hypotheses need to be based on proposed mechanisms, critical time windows for effects, prior knowledge of physical, physiologic, and immunologic development, as well as genetic pathways potentially influenced by the exposures. (creod.on.ca)

Identify, evaluate and manage current concerns and issues related to the pathophysiology, diagnosis and treatment of allergic and immunologic diseases. (acaai.org)
Global Journal of Allergy is an open access, peer reviewed, scholarly journal dedicated to publish articles in all areas of treatment of allergic and immunologic disease. (peertechzpublications.org)

Since 1989, the SWORD (surveillance of work related and occupational respiratory disease) project has provided a consistent and reliable estimate of the incidence and pattern of occupational respiratory diseases in the UK. (bmj.com)
6 In the USA, in 1987 the National Institute for Occupational Safety and Health instituted SENSOR (sentinel event notification system for occupational risks), with the aim to identify and characterise new case reports of targeted occupational diseases. (bmj.com)
A number of diseases have symptoms that mimic occupational asthma, such as asthma due to nonoccupational causes, chronic obstructive pulmonary disease (COPD), irritable larynx syndrome, hyperventilation syndrome, hypersensitivity pneumonitis, and bronchiolitis obliterans. (wikipedia.org)
Romano-Zelekha O, Graif Y, Garty BZ, Livne I, Green MS, Shohat T. Trends in the prevalence of asthma symptoms and allergic diseases in Israeli adolescents: results from a national survey 2003 and comparison with 1997. (medscape.com)
Although interstitial lung disease (ILD) is the primary manifestation of RA in the lungs, there is strong emerging evidence that airway diseases including asthma and chronic obstructive pulmonary disease (COPD) affect both the course and mortality of RA. (nih.gov)
Epidemiological studies conducted to date in adult populations provide evidence that airway diseases, including both asthma and COPD, are associated with increased incidence of RA. (nih.gov)
Allergic and immunologic diseases of the skin. (medecinesciences.org)
These cellular effects are important for host responses against infection and the development of allergic lung diseases like asthma. (vitamindwiki.com)
2007). Vitamin D may also play a role in the development of obstructive lung diseases like asthma and COPD (Janssens, Lehouck et al. (vitamindwiki.com)

Occupational rhinitis usually results in worsening of symptoms at the workplace and tends not to have seasonal variation in symptoms. (medscape.com)
Systemic immunologic and inflammatory aspects of allergic rhinitis. (medscape.com)
Worldwide time trends for symptoms of rhinitis and conjunctivitis: Phase III of the International Study of Asthma and Allergies in Childhood. (medscape.com)
Changing prevalence of allergic rhinitis and asthma. (medscape.com)
Prevalence of asthma, rhinitis and eczema in 6 - 7 years old students from the western districts of Sao Paulo City, using the standardized questionnaire of the "International Study of Asthma and Allergies in Childhood" (ISAAC)-phase IIIB. (medscape.com)
[ 26 ] Of patients with allergic rhinitis, 20% also have symptoms of asthma. (medscape.com)
An online search revealed that spider mites are important outdoor allergens that may contribute to work-related asthma and rhinitis in fruit farmers and children living in rural areas and produce a set of allergens that differ from those generated by indoor mites [ 9 ]. (biomedcentral.com)

Agents that can induce occupational asthma can be grouped into sensitizers and irritants. (wikipedia.org)

Appropriate animals models of isocyanate asthma will be instrumental to further our understanding of this disease. (cdc.gov)
1 Occupational asthma continues to be the most reported respiratory disease, although its incidence is lower than in previous years, with an estimated 822 cases (27% of total cases). (bmj.com)
It is an occupational lung disease and a type of work-related asthma. (wikipedia.org)
To understand the pathophysiology of immunologic and nonimmuno- allergic disease to those who research, treat, or manage allergic disease. (cdc.gov)
Астма Asthma is a disease of diffuse airway inflammation caused by a variety of triggering stimuli resulting in partially or completely reversible bronchoconstriction. (msdmanuals.com)
We hope the Conference will provide a unique platform as a knowledge base in the treatment and prevention of Allergies, Asthma, and Immunologic Disease. (conference-service.com)
Understand current and pipeline therapies for asthma and COPD and airway disease in RA, and how known therapies, or gaps, may help to move the field toward better treatments for airway disease with or without RA. (nih.gov)
The mechanisms by which isocyanates cause asthma remain unclear, hampering disease prevention, diagnosis, and treatment.7 It is assumed the reactive nature of N=C=O groups underlies isocyanate asthma, with a hapten-based mechanism as the most obvious pathway to pathogenesis.8 However, the critical "self" reaction targets for isocyanate in vivo remain uncertain. (cdc.gov)

The American Academy of Pediatrics has published a book about childhood environmental health problems, which states: "Avoiding environmental allergens and irritants is one of the primary goals of good asthma management" [AAPCEH 2003]. (cdc.gov)
Several studies support the importance of allergies and allergens in triggering and exacerbating asthma. (cdc.gov)
Sensitization to indoor allergens and the spores of outdoor molds is a risk factor for the development of asthma in children and adults. (cdc.gov)
Cockroach allergens also may increase a child's risk of developing asthma [IOM 2000, Etzel 2003]. (cdc.gov)
Diagnosis is based on occupational history, including assessment of job activities, allergens in the work environment, and a temporal association between work and symptoms. (msdmanuals.com)
A list of workplace airborne allergens that have been associated with occupational asthma can be found at the Commission des normes, de l'équité, de la santé et de la sécurité du travail . (msdmanuals.com)

The American College of Allergy, Asthma & Immunology (ACAAI) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. (acaai.org)
As required by the Accreditation Council for Continuing Medical Education (ACCME) and in accordance with the American College of Allergy, Asthma and Immunology (ACAAI) policy, all individuals in a position to control or influence the content of an activity must disclose all financial relationships with any ineligible company that have occurred within the past 24 months. (acaai.org)

In 1997, incidence rates of occupational asthma were highest among workers in the manufacture of wood products, textiles, and food (particularly grain products and crustaceans), in the production of precious and non-ferrous metals, rubber goods, detergents and perfumes, and in mining. (bmj.com)

As an example, acute inhalation MRLs may not be protective for health effects that are delayed in development or are' acquired following repeated acute insults, such as hypersensitivity reactions, asthma, or chronic bronchitis. (cdc.gov)
Immunologic responses to mold antigens cause hypersensitivity reactions, which can either be fast (allergy) or delayed (hypersensitivity). (majorrs.com)

Established in 1988, the mission of the Carl and Hazel Felt lab for Pulmonary Research is to advance the understanding of asthma and chronic bronchitis/COPD pathogenesis, including the study of new and current therapies. (nationaljewish.org)

Chemical irritation of the airway can result in the development of new onset asthma or worsening of prior symptoms of asthma. (medscape.com)
which can trigger or exacerbate an asthma attack in individuals with increased airway hyper responsiveness. (cdc.gov)
Like other types of asthma, it is characterized by airway inflammation, reversible airways obstruction, and bronchospasm, but it is caused by something in the workplace environment. (wikipedia.org)
Occupational asthma is reversible airway obstruction that develops after months to years of sensitization to an allergen encountered in the workplace. (msdmanuals.com)
In reactive airways dysfunction syndrome (RADS), which is nonallergenic, people with no history of asthma develop persistent, reversible airway obstruction after acute overexposure to irritant dust, fumes, or gas. (msdmanuals.com)
Airway inflammation persists even after removal of the acute irritant, and the syndrome is indistinguishable from asthma. (msdmanuals.com)
The Chu lab's mission is to understand the mechanisms of airway bacterial infections in patients with asthma or COPD, and to discover novel therapeutic approaches to restore host defense functions. (nationaljewish.org)

Provides information on mold and allergies from AAFA, a non-profit patient organization dedicated to improving the quality of life for people with asthma and allergies and their caregivers, through education, advocacy and research. (cdc.gov)
The goal of the Institute is to provide patients with comprehensive care and treatment for their asthma and allergies. (allergyasthma.us)

1 Blanc and Toren have shown that 9% of cases of adult asthma-including principally new onset asthma and, much more rarely, reactivation of pre-existing asthma-are attributable to occupational factors. (bmj.com)
3 From a practical point of view, addressing past and present occupational factors should be a priority in the assessment of adult onset asthma. (bmj.com)
Selective exclusion from work as a consequence of asthma is observed in childhood asthmatics already at the beginning of their working life and for current adult-onset asthmatics at the end of their working life [ 2 ]. (biomedcentral.com)
Age at asthma onset and asthma self-management education among adults in the United States. (wakehealth.edu)
Reliability in reporting asthma history and age at asthma onset. (wakehealth.edu)

Reactive airways dysfunction syndrome (RADS) is a severe form of irritant induced asthma where respiratory symptoms usually develop in the minutes or hours after a single accidental inhalation of a high concentration of irritant gas, aerosol, vapor, or smoke. (wikipedia.org)
In irritant-associated vocal cord dysfunction, which mimics asthma, abnormal apposition and closure of the vocal cords, especially during inspiration, occur after acute irritant inhalation. (msdmanuals.com)
4. A few cases of contact dermatitis had occurred in occupational settings in response to irritating enzyme preparations (e.g. proteases), but this is a non-immunologic phenomenon (also known as irritant contact dermatitis) unrelated to allergic contact hypersensitivity, which is a cell mediated delayed type hypersensitivity. (europa.eu)

Finally, an allergic response to inhaled Aspergillus results in allergic bronchopulmonary aspergillosis (ABPA) and severe asthma with fungal sensitisation. (bmj.com)

Furthermore, the most common cause of occupational asthma in the workplace are isocyanates. (wikipedia.org)
Isocyanates have been a leading chemical cause of occupational asthma since their utility for generating polyurethane was first recognized over 60 years ago, yet the mechanisms of isocyanate asthma pathogenesis remain unclear. (cdc.gov)

7 This system has led to reports of previously unrecognised causes of occupational asthma. (bmj.com)

We hypothesized that inhalation of vapor phase toluene diisocyante (TDI) will lead to immunologic sensitization in mice and that subsequent challenge will induce pathology and immune system alterations indicative of asthma found in humans. (cdc.gov)
Sensitization to house dust mites is an important risk factor for asthma exacerbations and the development of asthma. (cdc.gov)
Ninety-three (24%) subjects showed incident occupational rhinoconjunctivitis symptoms, and 37 (9.6%) had symptoms combined with skin sensitization to an animal-derived allergen. (occupationalasthma.com)
The overall increase in IgE concentrations found in humans with red- cedar asthma (Frew 1995, Paggiaro 1987) indicates an overall sensitization of the immune system to a foreign substance. (reptilestar.com)

Determinants include immunologic and target-organ susceptibility. (occupationalasthma.com)

Given a mean prevalence of asthma of about 5%, about 0.2-0.5% of young adults become asthmatics or have their asthma exacerbated because of their occupations. (bmj.com)

Inhalation of agents in the workplace can induce asthma in a mechanisms involved in asthma. (cdc.gov)

The U.S. Occupational Safety and Health Administration (OSHA) has established 8-hour time-weighted averages (TWA) on the airborne concentrations of hazardous chemicals. (medscape.com)

To diagnose occupational asthma it is necessary to confirm the symptoms of asthma and establish the causal connection with the work environment. (wikipedia.org)

Active asthma and the prevalence of physician-diagnosed COPD. (wakehealth.edu)

Recent advances have been made in the of host factors, polymorphisms, and candidate genes associated characterization of the immune response to low-molecular- with occupational asthma may improve our understanding of weight agents. (cdc.gov)

Isocyanates used in polyurethane paints and foam are commonly associated with asthma. (medscape.com)

A commonly asked employer question is why other coworkers do not have similar complaints of occupational asthma (OA). (medscape.com)

There two types of occupational asthma-one has an immune-mediated mechanism of action and the other a nonimmune-mediated mechanism. (msdmanuals.com)

Fragrance as an occupational allergen. (medecinesciences.org)

While many studies have investigated asthma as a risk factor for RA [4], less is known about how RA and asthma contribute to clinical outcomes [5]. (nih.gov)

Another type of work-related asthma is work-exacerbated asthma (WEA) which is asthma worsened by workplace conditions but not caused by it. (wikipedia.org)
Numerous chemicals and other agents that may be encountered in the workplace have been identified as causing occupational asthma. (msdmanuals.com)
In occupational safety and health (OSH), setting worker well-being as an outcome implies a paradigm shift beyond the prevention of workplace illness and injury or health promotion. (uth.edu)

The analysis of data from the European Community Respiratory Health Survey (ECRHS) conducted in western European and other industrialised countries has provided new information on which jobs carry a high risk of asthma. (bmj.com)
Provides search results on Indoor Environmental Quality and Mold from NIOSHTIC, a searchable bibliographic database of occupational safety and health publications, documents, grant reports, and journal articles supported in whole or in part by the National Institute for Occupational Safety and Health. (cdc.gov)
When work ability is reduced due to other health conditions, having asthma makes it even more difficult to return to work. (biomedcentral.com)
The following tables show occupations that are known to be at risk for occupational asthma, the main reference for these is the Canadian Centre for Occupational Health and Safety. (mdwiki.org)
Researchers at the Southwest Center for Occupational and Environmental Health (SWCOEH) in the Department of Epidemiology, Human Genetics and Environmental Sciences (EHGES) at UTHealth School of Public Health have a 15+ year history of safety and ergonomics research in the U.S. dairy industry . (uth.edu)
The goal of the pilot projects research training program (PPRTP) is to enhance the SWCOEH's regional outreach efforts in research training and to foster stronger inter-institutional ties in occupational health research within Public Health Region 6, which includes Arkansas, Louisiana, New Mexico, Oklahoma and Texas. (uth.edu)
Researchers at the Southwest Center for Occupational and Environmental Health (SWCOEH) in the Department of Epidemiology, Human Genetics and Environmental Sciences (EHGES) at UTHealth School of Public Health are conducting 9000 household interviews on working conditions and health in six Central American countries , in an effort to guide policies that could improve the region's health. (uth.edu)
These cases were identified by the occupational health physician during the annual screening of FW working in the Mountains of north-eastern Sicily. (biomedcentral.com)
Occupational Safety and Health Administration studies show that as many as one in three health care workers may have some form of hand irritation. (rdhmag.com)

Examples of substances that can result in asthma include acid anhydrides used in epoxy adhesives and paints. (medscape.com)
Sensitizer-induced occupational asthma is an immunologic form of asthma which occurs due to inhalation of specific substances (i.e., high-molecular-weight proteins from plants and animal origins, or low-molecular-weight agents that include chemicals, metals and wood dusts) and occurs after a latency period of several weeks to years. (wikipedia.org)

The most typical signs of asthma in people with the condition include runny nose, eye discomfort, coughing, congestion, and asthma attacks. (majorrs.com)

Anatomy10

Organisms5

Diseases37

Chemicals and Drugs45

Analytical, Diagnostic and Therapeutic Techniques and Equipment40

Psychiatry and Psychology5

Phenomena and Processes16

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena6

Humanities1

Information Science2

Named Groups2

Health Care42

Geographicals4

Exposure45

Exposures10

Treatment of allergic and immunologic2

Diseases9

Rhinitis7

Induce occupational asthma1

Disease8

Allergens6

Immunology2

19971

Hypersensitivity reactions2

Therapies1

Airway7

Allergies2

Onset5

Irritant3

Severe Asthma1

Cause of occupational asthma2

Causes of occupational asthma1

Sensitization4

Determinants1

Prevalence of asthma1

Mechanisms1

Airborne1

Symptoms of asthma1

COPD1

Characterization1

Isocyanates1

Commonly1

Immune1

Allergen1

Outcomes1

Workplace3

Health9

Substances2

Runny nose1