AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceHealth Care
ImmunohistochemistryImmunoenzyme TechniquesRNA, MessengerReverse Transcriptase Polymerase Chain ReactionTumor Markers, BiologicalIn Situ HybridizationBlotting, WesternRats, Sprague-DawleyDisease Models, AnimalCells, CulturedGene ExpressionPrognosisMicroscopy, ElectronTissue Array AnalysisMicroscopy, Electron, ScanningGene Expression Regulation, NeoplasticKi-67 AntigenTime FactorsMice, Inbred C57BLCell Line, TumorCell ProliferationApoptosisPhenotypeUp-RegulationFluorescent Antibody Technique, IndirectAdenocarcinomaBiopsyNeoplasm ProteinsRats, WistarBreast NeoplasmsCell DifferentiationPolymerase Chain ReactionStaining and LabelingMicroscopy, ConfocalIn Situ Hybridization, FluorescenceMutationMicroscopy, Electron, TransmissionEpithelial CellsMolecular Sequence DataNeuronsParaffin EmbeddingGene Expression ProfilingCell CountCell DivisionGene Expression RegulationAntibodies, MonoclonalNeoplasm InvasivenessIn Situ Nick-End LabelingSignal TransductionEpitheliumTissue FixationNeoplasm StagingCell MovementFluorescent Antibody TechniqueReceptor, erbB-2BrainMembrane ProteinsBiological MarkersDisease ProgressionTissue DistributionCarcinoma, Squamous CellPregnancyReal-Time Polymerase Chain ReactionHistocytochemistryMice, KnockoutCarcinomaMicroscopy, FluorescenceKeratinsRetinaAnimals, NewbornTumor Suppressor Protein p53Flow CytometryProliferating Cell Nuclear AntigenCell LineKidneyBase SequenceMice, TransgenicActinsGlial Fibrillary Acidic ProteinVimentinSkinIntestinal MucosaLymphatic MetastasisOligonucleotide Array Sequence AnalysisVascular Endothelial Growth Factor ALung NeoplasmsAntigens, CDEnzyme-Linked Immunosorbent AssayNerve Tissue ProteinsDown-RegulationLungMacrophagesGene Expression Regulation, DevelopmentalFibroblastsMice, Inbred BALB CImmunoblottingCell NucleusTumor Cells, CulturedEndometriumNeovascularization, Pathologic
AIMMPathologyTumorsExpert Review of Molecular DiagnosticsOncology2017GeneticsBiomarkersColorectal cancerDiagnosticsGliomasMorphologicTumorDiagnosticRetinalDiagnosisCancerCytogeneticUltrastructuralCarcinogenesisCellularCellsLaboratoryContextTissueCharacteristicsMethodsBiologyMarkersExpressionFeaturesProteinAnalysisStudiesExperienceIdentification
AIMM1
Pathology5
  • He is currently an Attending Medical Geneticist for the Molecular Genetic Pathology Laboratory at Stanford Health Care where he previously served as an Assistant Lab Director. (stanford.edu)
  • Several chapters focus on new trends in the field, e.g. immune therapy and identification of biomarkers, molecular oncogenesis including genetic susceptibility, and molecular diagnostic pathology. (stanford.edu)
  • Recognize how results from cytogenetics and molecular genetics diagnostic tests and from prenatal screening tests can be integrated with results from pathology and laboratory medicine to provide the referring physician a more comprehensive clinical picture of the patient. (case.edu)
  • Communicate to appropriate genetics laboratory staff (and also interpret) the pathology review, flow cytometry and/or immunohistochemistry results from patient samples that are found by the genetics laboratory to have an unusual cytogenetic and/or molecular genetic result. (case.edu)
  • Comparing cytogenetic findings in cancer patients with pathology/morphology review, flow cytometry and immunohistochemistry results. (case.edu)
Tumors3
  • [ 10 ] are often focal or diffusely positive for small cell bladder tumors by immunohistochemistry, and they are useful tools to help establish a diagnosis. (medscape.com)
  • Her research interest focuses on the molecular oncology and immunotherapies of solid tumors and she published more than 40 peer reviewed papers. (stanford.edu)
  • Soft tissue sarcomas are currently classified on the basis of the 2013 WHO classification of soft tissue tumors that integrate conventional morphology with immunohistochemistry and molecular genetics. (dtrf.org)
Expert Review of Molecular Diagnostics1
  • Expert Review of Molecular Diagnostics. (wustl.edu)
Oncology1
  • Molecular and clinical oncology. (ufl.edu)
20171
Genetics7
  • Dr. Costa received his BS in Genetics from University of California at Davis, his PhD in Genetics from Stanford University School of Medicine, and his ABMGG Clinical Molecular Genetics and Genomics fellowship training from Stanford University School of Medicine. (stanford.edu)
  • This book provides essential information on recent advances in molecular genetics, epidemiology, translational research, and the latest results of clinical trials on mesothelioma. (stanford.edu)
  • The book consists of 5 themed sections on: epidemiology, pathogenesis, screening and early detection, molecular genetics, and clinical aspects and management. (stanford.edu)
  • Molecular genetics is increasingly used for diagnostic purposes to distinguish specific subtypes of sarcomas, to support diagnosis in non-canonical clinical presentations and also to distinguish true sarcomas from benign mimickers. (dtrf.org)
  • The goal of the rotation in the clinical genetics laboratory is to provide the Resident with an understanding of and an appreciation for the laboratory techniques and tests used in the clinical cytogenetics, clinical molecular genetics and prenatal screening laboratories. (case.edu)
  • Be familiar with routine procedures used in routine clinical cytogenetics, clinical molecular genetics and prenatal screening tests. (case.edu)
  • Be familiar with PCR and other DNA-based procedures used in the molecular genetics laboratory and their utility in a variety of clinical and research applications. (case.edu)
Biomarkers1
  • Immunohistochemistry is also widely used in basic research to understand the distribution and localization of biomarkers and differentially expressed proteins in different parts of a biological tissue. (wikipedia.org)
Colorectal cancer1
  • Universal screening for Lynch syndrome in operated colorectal cancer by immunohistochemistry: a cohort of patients in Liaoning province, China. (cdc.gov)
Diagnostics2
  • The rotation in Clinical Cytogenetics lasts for one month in conjunction with the rotation in Molecular Diagnostics and the Prenatal Screening Laboratory. (case.edu)
  • Presenting a 30 minute seminar on a topic related to cytogenetics, prenatal screening, or molecular diagnostics (topic to be mutually agreed upon between the Teaching staff and the Resident. (case.edu)
Gliomas1
Morphologic1
  • Using an approach that includes consideration of the morphologic features, appropriate immunohistochemistry, and correct clinical context aids in making the proper diagnosis. (medscape.com)
Tumor3
  • Urinary cytology often reveals single and loosely cohesive clusters of tumor cells with typical small cell carcinoma morphology. (medscape.com)
  • By immunohistochemistry, the tumor cells are positive for inhibin and negative for chromogranin and S100. (cap.org)
  • Single Tumor Cells With Epithelial-Like Morphology Are Associated With Breast Cancer Metastasis // Front. (tnimc.ru)
Diagnostic3
  • The cytogenetic and molecular diagnostic supervisors will report to the director on the resident's understanding of laboratory test protocols, as well as both routine and specialized laboratory techniques (using a scale of 1 - 10). (case.edu)
  • The Glioma-IRE project - Molecular profiling in patients with glioma: steps toward an individualized diagnostic and therapeutic approach. (cdc.gov)
  • The journal spotlights ongoing advances in the uses of electron microscopic and immunohistochemical techniques, correlations of ultrastructural data with light microscopy, histochemistry, immunohistochemistry, biochemistry, cell and tissue culturing, electron probe analysis, and important new investigative, clinical, and diagnostic EM methods. (360qikan.com)
Retinal1
Diagnosis1
  • Our goal is to highlight the importance of coronavirus morphology and cellular localization in diagnosis and detection. (cdc.gov)
Cancer3
  • After publication of the previous article, Molecular and Clinical Effects of Deuterium Depleted Water in Treatment and Prevention of Cancer in Positive Health Online a demand emerged for the explanation of the use of DDW in daily practice addressing the correlation between the application of deuterium depletion, life skills and diet. (positivehealth.com)
  • Molecular mechanisms of breast cancer invasion and metastasis. (tnimc.ru)
  • Harmonization of PD-L1 Immunohistochemistry Assays for Lung Cancer: A Working Progress. (ufl.edu)
Cytogenetic2
  • the resident should be familiar with the FISH and/or molecular techniques used in delineating a chromosome abnormality identified during a routine cytogenetic analysis. (case.edu)
  • Attending the Laboratory's weekly abnormal meeting and discussing abnormal patient results, both cytogenetic and molecular. (case.edu)
Ultrastructural1
  • Overview of the ultrastructural features of coronavirus morphology as seen by negative stain and thin section. (cdc.gov)
Carcinogenesis1
  • 2. Asbestos and mesothelioma: What is recent advance in research on asbestos-induced molecular carcinogenesis? (stanford.edu)
Cellular1
  • Specific molecular markers are characteristic of particular cellular events such as proliferation or cell death (apoptosis). (wikipedia.org)
Cells2
  • Our facilities provide the opportunity to study protein structure, molecular probes and drug design, system biology and molecular interactions in cells and tissues. (lu.se)
  • Osteoblasts were obtained from human bone marrow cells even in the absence of growth factors and showed a typical morphology. (bvsalud.org)
Laboratory2
  • Attending biweekly cytogenetics/molecular laboratory meeting. (case.edu)
  • The laboratory director will evaluate (on a scale of 1 - 10) the resident's proposed FISH and/or molecular approach to studying an unusual chromosome abnormality encountered in the lab. (case.edu)
Context1
  • The majority of classic differentiation markers tend to show good sensitivity, however, associated with rather limited specificity, making interpretation in context with morphology mandatory. (dtrf.org)
Tissue1
  • Preparation of the sample is critical to maintaining cell morphology, tissue architecture and the antigenicity of target epitopes. (wikipedia.org)
Characteristics1
  • While factors influencing outcomes of rhabdomyosarcoma (RMS) in developed countries have evolved from clinical characteristics to molecular profiles, similar data from developing countries are scarce. (ecancer.org)
Methods1
  • Methods in molecular biology (Clifton, N.J.). 2616 , p. 355-366 12 p. (lu.se)
Biology1
  • 2006-2012: MD student, Department of Biochemistry and Molecular Biology, Siberian State Medical University. (tnimc.ru)
Markers2
  • even immunohistochemistry may fail to demonstrate expression of these markers. (medscape.com)
  • A cocktail of cytokeratin markers is often nonreactive, but low molecular cytokeratin, CAM5-2, and epithelial membrane antigen (EMA) are mostly positive. (medscape.com)
Expression1
Features1
  • We describe the clinical and molecular features of a child who presented with a large abdominal mass, AML, and a new CK, involving chromosomes 11, 16, and 19 leading to a KMT2A-MLLT1 fusion and 2 extra copies of the ELL gene, thus resulting in the concurrent overexpression of MLLT1 and ELL. (cancerindex.org)
Protein1
  • With the help of various forms of mass spectrometry, synchrotron radiation, protein production & labelling, and bioinformatics, our facilities provide the opportunity to study protein structure and dynamics, molecular probes and drug design. (lu.se)
Analysis1
Studies1
  • In turn, it discusses recent molecular pathological studies on mesothelioma, which claim to offer more accurate classifications than traditional morphology and immunohistochemistry-based approaches. (stanford.edu)
Experience1
  • Collaborative Multi-institutional Experience in Comparing PD-L1 Immunohistochemistry Assays: Concordance of SP142 and 22C3 Immunoreactivity. (ufl.edu)
Identification1
  • Nevertheless, the identification of novel additional molecular alterations is of great interest, opening to new prognostic and therapeutic strategies for such heterogeneous hematological disease. (cancerindex.org)