• Immunoglobulin E (IgE) is a type of protein in the body called an antibody. (kidshealth.org)
  • These people have high levels of an allergy-causing antibody (a type of immune protein in the body) called immunoglobulin E (IgE). (kidshealth.org)
  • Anti-D immunoglobulin treatment for thrombocytopenia associated with primary antibody deficiency. (medscape.com)
  • Allergic (extrinsic) asthma is associated with immunoglobulin E (IgE)-an antibody generated by the immune system, in this case, in response to a normally harmless substance. (verywellhealth.com)
  • At presentation, 47% of subjects had antibodies directed against C. pneumoniae , and 38% (20) demonstrated an increase in C. pneumoniae antibody levels, with 15 demonstrating a rise in immunoglobulin A concentration. (ersjournals.com)
  • A typical immunoglobulin (antibody, Ig) in jawed vertebrates is composed of two identical heavy chains (IGH) and two identical light chains (IGL) and provides defense against all extracellular and some intracellular pathogens ( Klein and Hořejší 1997 ). (pubmedcentralcanada.ca)
  • Immunoglobulin G (IgG) , the most abundant type of antibody, is found in all body fluids and protects against bacterial and viral infections. (kidshealth.org)
  • Immunoglobulin M (IgM) , which is found mainly in the blood and lymph fluid, is the first antibody to be made by the body to fight a new infection. (kidshealth.org)
  • Immunoglobulin D (IgD) , which exists in small amounts in the blood, is the least understood antibody. (kidshealth.org)
  • Immunoglobulin D (IgD) deficiency is a defect of humoral immunity that is characterized by abnormally low serum levels of IgD immunoglobulins. (medscape.com)
  • male-to-female ratio=3:1) and 94.4% had elevated pre-treatment serum immunoglobulin G4 levels. (hkmj.org)
  • We identified pre-treatment serum immunoglobulin G4 to be associated with multisystem disease, especially with salivary gland involvement, highlighting its potential for disease prognostication and monitoring. (hkmj.org)
  • Human immunoglobulin IgE is the least abundant Ig in the serum and does not activate the complement pathway. (bio-rad-antibodies.com)
  • To investigate this possibility we utilized a radio‐allergosorbent test assay for detecting serum immunoglobulin E specific for Streptococcus pneumoniae, an organism commonly isolated from the respiratory tract of smokers with chronic bronchitis. (elsevier.com)
  • Individual sera were considered positive for pneumococcus‐specific immunoglobulin E if the binding was at least twice the non‐specific binding at the total immunoglobulin E concentration of the particular serum. (elsevier.com)
  • The BIOMED IgE Reagent is intended for the quantitative, immunological turbidimetric in vitro determination of immunoglobulin E in human serum and plasma using clinical chemistry analyzers. (biomed.de)
  • 1. Distinguishing between broadly migrating monoclonal proteins and restricted polyclonal immunoglobulin patterns on serum electrophoresis. (mayocliniclabs.com)
  • To determine the differences between total and serum-specific immunoglobulin E levels in patients with type 1 allergic conjunctivitis and asymptomatic contact lens wearers. (asianjo.com)
  • The correlation of total serum immunoglobulin E level of asymptomatic contact lens wearers with contact lens wearing time, and total duration of contact lens use was also evaluated. (asianjo.com)
  • Total serum immunoglobulin E levels were detected by enzyme-linked immunosorbent assay. (asianjo.com)
  • The mean level of total serum immunoglobulin E was greater for patients with type 1 allergic conjunctivitis than for contact lens wearers and controls. (asianjo.com)
  • Serum-specific immunoglobulin E detected in patients with type 1 allergic conjunctivitis was against indoor, food, and outdoor allergens, while serum-specific immunoglobulin E detected in contact lens wearers was only against outdoor allergens. (asianjo.com)
  • A statistically significant correlation was found for total serum immunoglobulin E levels of contact lens wearers with contact lens wearing time. (asianjo.com)
  • These results suggest that differences in serum total and specific immunoglobulin E levels exist between patients with type 1 allergic conjunctivitis and CL wearers and controls. (asianjo.com)
  • Immune markers were blood leukocyte counts, plasma cytokines, serum C-reactive protein and immunoglobulins. (biomedcentral.com)
  • Because of the less-than-robust response to therapy and impact on choice of optimal chemotherapy and prognosis, chronic kidney disease has drawn attention in the treatment of multiple myeloma, a malignant hematologic disorder that can produce significant amounts of monoclonal immunoglobulin free light chains (FLCs). (jci.org)
  • To the extent that the experiments reflect the human condition, these studies offer insights into the pathogenesis of progressive kidney failure in the setting of lymphoproliferative disorders, such as multiple myeloma, that feature increased circulating levels of monoclonal immunoglobulin fragments that require metabolism by the kidney. (jci.org)
  • OBJECTIVE: Immunoglobulin free light chain (FLC) abnormalities are frequent in patients with monoclonal gammopathies and kidneys are the most affected organs in these patients. (tjh.com.tr)
  • It is concluded that Hodgkin cells do not contain a 'monoclonal' immunoglobulin product. (meta.org)
  • Intravenous immunoglobulin (IVIg) is beneficial in other autoimmune diseases. (nih.gov)
  • Intravenous immunoglobulin therapy (IVIg 0.4 g/kg×5 days) markedly reduced the severe pain and muscle weakness in the legs. (pubmedcentralcanada.ca)
  • 4 , 5 , 6 , 7 Here we report a patient with PDN, in whom intravenous immunoglobulin therapy (IVIg) treatment dramatically ameliorated severe neuropathic pain and muscle weakness in the lower extremities. (pubmedcentralcanada.ca)
  • Is intravenous immunoglobulin (ivig) useful for treating ulcerative colitis? (healthtap.com)
  • Why do they give ivig (intravenous immunoglobulin)? (healthtap.com)
  • Can Intravenous Immunoglobulin or IVIG really cure Neuropathy and neuromuscular disorders? (healthtap.com)
  • If you receive a blood product like ivig (intravenous immunoglobulin) can you still be an organ donor later on? (healthtap.com)
  • Can anyone experienced with ivig (intravenous immunoglobulin) describe what one should expect? (healthtap.com)
  • Does intravenous immunoglobulin (ivig) infusions help someone with IgG defiency? (healthtap.com)
  • Can you receive a blood product like ivig (intravenous immunoglobulin) if you are pregnant? (healthtap.com)
  • After diagnosis, treatment includes replacement of intravenous immunoglobulin (IVIG), which significantly reduces the risk of infection (6). (ac.ir)
  • Three different nonprotective immunoglobulin (Ig) G23 mAbs to cryptococcal capsular polysaccharide were used to study the interaction between the IgG3 isotype and protective IgG1 and IgG2a mAbs in murine cryptococcal infection. (rupress.org)
  • Publications] SHIMIZU,A.: 'Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene. (nii.ac.jp)
  • A variety of mAb products have been established, ranging from conventional full-length immunoglobulins, mostly isotype G (IgG), to fusion proteins and minimal fragments. (biomedcentral.com)
  • Publications] IWASATO,T.: 'Biased distribution of recombination sites within Sregions in TGF-β-induced immunoglobulin class switch recombination. (nii.ac.jp)
  • A Case of Bruton's Disease with Normal Immunoglobulin G Level', Iranian Journal of Immunology , 11(1), pp. 59-63. (ac.ir)
  • We stimulated antigen-exposed splenocytes, followed by the accumulation of mutations in immunoglobulin genes. (nii.ac.jp)
  • The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. (genecards.org)
  • Introduction of human .GAMMA.1 immunoglobulin genes into fertilized mouse eggs. (nii.ac.jp)
  • Immunoglobulins consist of ypsilon-shaped proteins and their task is to detect and fend off pathogens and substances such as viruses, bacteria, toxins or allergens that enter the body. (biomed.de)
  • Publications] Han,H.: 'Regulated expression of immunoglobulin trans-mRNA consisting of the variable region of transgenic μ chain and constant regions of endogenous isotypes. (nii.ac.jp)
  • An allergen-specific immunoglobulin E (IgE) blood test is done to check whether a person is allergic to a particular substance. (rchsd.org)
  • Food-specific immunoglobulin G (IgG) testing is being increasingly used in children to diagnose food allergy and intolerance with often positive results for multiple foods. (hkmj.org)
  • Isolation and partial characterization of immunoglobulins of goldfish (Carassius auratus) and carp (Cyprinus carpio). (nii.ac.jp)
  • Characterization of a teleost immunoglobulin:the immune macroglobulin from the channel catfish, Ictalurus punctatus. (nii.ac.jp)
  • Publications] KUZE,K.: 'Characterization of the enhancer region for germline transcription of the gamma 3 constant region gene of the human immunoglobulin. (nii.ac.jp)
  • IGL (Immunoglobulin Lambda Locus) is a Protein Coding gene. (genecards.org)
  • Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. (genecards.org)
  • A complement fixing region of an immunoglobulin molecule. (jax.org)
  • One hundred and three patients (90 nonatopics and 13 atopics) with respiratory infections to various viral agents were studied retrospectively with respect to IgE immunoglobulin levels during acute (1 to 7 days) and convalescent (8 to 30 days) phases of infection. (nih.gov)
  • Clinical history taking, sputum induction (0.9% saline), spirometry and acute and convalescent serology for C. pneumoniae immunoglobulins A and G were performed. (ersjournals.com)
  • Recombinant fragment within Human Polymeric immunoglobulin receptor/PIGR aa 1-650. (abcam.com)
  • His-tagged recombinant human Polymeric immunoglobulin receptor/PIGR protein. (abcam.com)
  • Also known as Osteoclast-associated immunoglobulin-like receptor (Osteoclast-associated receptor) (hOSCAR) (Polymeric immunoglobulin receptor 3) (PIgR-3) (PIgR3) (Poly-Ig receptor 3). (mybiosource.com)
  • Publications] SHIMIZU,A.: 'Synthesis and regulation of trans-mRNA encoding immunoglobulin ε heavy chain. (nii.ac.jp)
  • We investigated the role of the Th2 pathway by exploring the relationships between components of the Th2 pathway, interleukin (IL)-10, IL-4, immunoglobulin E (IgE), and eosinophils, and prognostic markers of NHL. (tjh.com.tr)
  • Genetically controlled intraspecific differences between immunoglobulins (allotypes) provide valuable markers for the study of the quantitative expression of allelic and nonallelic alternative forms of immunoglobulins (Igs) during the normal development of rabbits. (meta.org)
  • The effect of rat immunoglobulins and immune complexes on the locomotor function of rat polymorphonuclear leukocytes (PMN) was investigated in vitro. (uclouvain.be)
  • The changes in IgE levels during the viral infectious period are discussed in terms of possible cellular mechanisms that may control IgE immunoglobulin. (nih.gov)
  • A relationship between elevated scrum immunoglobulin E levels and smoking has been demonstrated in epidemiological studies. (elsevier.com)
  • Immunoglobulin levels are also used as part of an evaluation for autoimmune conditions such as juvenile idiopathic arthritis , lupus , and celiac disease . (kidshealth.org)
  • Polyvalent immunoglobulin G (IgG) products obtained by fractionation of human plasma are used to treat a broad range of conditions, including immunodeficiency syndromes and autoimmune, inflammatory, and infectious diseases. (elsevier.com)
  • an immunoglobulin protein secreted by activated plasma cells, which evolve from B cells. (thebody.com)
  • Replacement therapy is not practical for IgAD because of the short half-life of IgA and the relative paucity of IgA in commercial immunoglobulin preparations. (medscape.com)
  • Precautions must be used in the administration of IV immunoglobulin and other blood products in patients with IgAD because IV immunoglobulin preparations and other blood products contain at least small amounts of IgA. (medscape.com)
  • Exposure to thimerosal, a mercury-containing preservative that is used in vaccines and immunoglobulin preparations, has been hypothesized to be associated with increased risk of autism spectrum disorder (ASD). (aappublications.org)
  • This study was designed to examine relationships between prenatal and infant ethylmercury exposure from thimerosal-containing vaccines and/or immunoglobulin preparations and ASD and 2 ASD subcategories: autistic disorder (AD) and ASD with regression. (aappublications.org)
  • Exposure to thimerosal in vaccines and immunoglobulin preparations was determined from electronic immunization registries, medical charts, and parent interviews. (aappublications.org)
  • In our study of MCO members, prenatal and early-life exposure to ethylmercury from thimerosal-containing vaccines and immunoglobulin preparations was not related to increased risk of ASDs. (aappublications.org)
  • We retrospectively evaluated all patients with immunoglobulin G4-related disease between January 2003 and December 2015 in Queen Mary Hospital and combined this with patient data extracted from previous local publications. (hkmj.org)
  • Intravenous immunoglobulin therapy for asthma: time for a closer look? (bmj.com)
  • In that way, checking for the presence of specific immunoglobulins in the blood can be helpful in diagnosing or ruling out infections or certain other illnesses. (kidshealth.org)
  • Genetic rearrangements occur during the maturation of B lymphocytes, eventually resulting in the surface expression of both immunoglobulin M (IgM) and IgD on mature B cells. (medscape.com)
  • With immunohistochemistry, immunoglobulin (Ig) G4-positive cells constituted an average of 60 cells per high-power field (magnification, x 40) and the ratio of IgG4:IgG positive cells was more than 40% ( Figs 2c and 2d ). (hkmj.org)
  • Human immunoglobulin E (IgE) is expressed on the surface of mature B cells. (bio-rad-antibodies.com)
  • The proportions of cells that differentiate to produce allelic forms of immunoglobulins during normal development depend on the particular heterozygous genotype. (meta.org)
  • The immunoglobulins in all the positively stained Hodgkin cells were of IgG type, but staining for IgA, D and E was negative. (meta.org)
  • The diagnosis of the biomarker immunoglobulin E is performed to identify various allergens in the body that can trigger an allergy or parasite infestation. (biomed.de)
  • An investigation of the distribution of immunoglobulins in the external secretions of the hamster revealed the predominance of γA. (jimmunol.org)
  • Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils. (medscape.com)
  • Doctors also rely on the immunoglobulin test as one of the tools to help diagnose immunodeficiencies (when the immune system isn't working properly). (kidshealth.org)
  • The present study demonstrated that during the process of metabolism of immunoglobulin FLCs, ROS activated the STAT1 pathway in proximal tubule epithelium. (jci.org)
  • We described the clinical features and treatment modalities of the largest cohort of immunoglobulin G4-related disease in our locality thus far. (hkmj.org)
  • Diagnosis of the disease is suggested by lymphoid hypoplasia (minimal or no tonsillar tissue and no palpable lymph node) and total immunoglobulins level less than 100 mg/dl. (ac.ir)
  • Below are the list of possible Osteoclast-associated immunoglobulin-like receptor products. (mybiosource.com)
  • Immunoglobulin G4-related disease remains an under-recognised and evolving disease. (hkmj.org)
  • Hepatobiliary and pancreatic system, salivary gland, lymph node, and eye were the most common organ systems involved in immunoglobulin (Ig) G4-related disease in Hong Kong. (hkmj.org)
  • Immunoglobulin (Ig) G4-related disease (IgG4-RD) is a systemic immune-mediated disease unifying what were previously considered to be unrelated individual organ disorders. (hkmj.org)