• The exact immunogen sequence used to generate this antibody is proprietary information. (abcam.com)
  • If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. (abcam.com)
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. (cusabio.com)
  • Each antibody is crafted with care according to rigorous protocols for immunogen design and preparation, presentation to host animal, and high-affinity purification against the antigen. (abcepta.com)
  • Recombinant fragment within Human ERK1 + ERK2 aa 150 to the C-terminus. (abcam.com)
  • Detects endogenous levels of human p42 and p44 MAP kinase (Erk1 and Erk2) only when phosphorylated either individually or dually at Thr202 and Thr204 of Erk1 (Thr185 an Tyr187 of Erk2). (lsbio.com)
  • MAP3K8 is one of the MAP kinase kinase (MAPKK) kinases that regulates the ERK1/ERK2 pathway in response to IL-1, facilitating IL-8 and MIP-1 beta production. (bio-techne.com)
  • Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. (arigobio.com)
  • MAPK1 (ERK2) is a serine/threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. (thermofisher.com)
  • MAP3K8 activates I kappaB kinases and induces the nuclear production of NF-kappa B. Human MAP3K8 shares 97% and 98% amino acid (aa) identity with mouse and rat MAP3K8, respectively, within the region used as an immunogen. (bio-techne.com)
  • Subsequent subcutaneous injections of 200 ug immunogen in Incomplete Freunds Adjuvant had been carried out right up until the serum titer from the mouse was half maximal at a dilution of two × ten four as judged by ELISA, with 50 ng of O Ab42 connected per very well from the strong phase. (liverxreceptor.com)
  • The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance. (affbiotech.com)
  • Bulk Order Inquiry for Anti-ERK2 (central region) Antibody ------- (please add any order requirements, including desired quantity, timing, etc. (phosphosolutions.com)
  • The antibody detects 42 and 44 kDa* proteins corresponding to ERK1 and ERK2 on SDS-PAGE immunoblots of human A431 epithelial cells. (phosphosolutions.com)
  • MEK1 and MEK2 activate ERK1 and ERK2 through phosphorylation of activation loop residues Thr-202/Tyr-204 and Thr-185/Tyr-187, respectively. (phosphosolutions.com)
  • ERK1 and ERK2 encode 42 and 44 kD protein kinases and share 85% homology. (biolegend.com)
  • The blots were probed with polyclonal anti-ERK2 (a.a. 181-195) (lanes 1 & 2), anti-ERK2 (Thr-188) (lanes 3 & 4), anti-ERK1/2 (Thr-202/Tyr-204) (lanes 5 & 6), or monoclonal anti-ERK1 (C-terminal region) (lanes 7 & 8). (phosphosolutions.com)
  • ERK2 synthetic peptide (coupled to carrier protein) corresponds to amino acids from the central region of mouse ERK2. (phosphosolutions.com)
  • Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. (arigobio.com)