Loading...
  • tissues
  • Because the antibodies and accompanying cells of inflammation can affect tissues anywhere in the body, lupus has the potential to affect a variety of areas. (livehopelupus.org)
  • People with lupus produce abnormal antibodies in their blood that target tissues within their own body rather than foreign infectious agents. (livehopelupus.org)
  • diagnosis
  • In patients with findings of rheumatoid arthritis, a positive rheumatoid factor titer suggests the diagnosis, but as with antinuclear antibodies, it is not specific and can occur in other conditions. (aafp.org)
  • A positive anticyclic citrullinated peptide antibody titer is more specific for rheumatoid arthritis and can help confirm the diagnosis. (aafp.org)
  • These blood tests include antibodies to anti-dsDNA and anti-Sm, which are specific to the diagnosis of lupus. (livehopelupus.org)
  • proteins
  • As a privately held company, eBioscience offers one of the world's largest selections of antibodies, ELISAs and proteins for Life Science research and diagnostic. (optometricmanagement.com)
  • Antibodies are one of the three classes of globulins (plasma proteins) in the blood that contribute to maintaining colloidal oncotic pressure. (livehopelupus.org)
  • Another differentiator is that people with SSc often have antibodies to an antigen called Scl-70 (topoisomerase I) or antibodies to centromere proteins. (livehopelupus.org)
  • disease
  • Similarly, antinuclear antibodies can be present in patients with scleroderma, mixed connective tissue disease, and dermatomyositis or polymyositis. (aafp.org)
  • In SLE patients with serious brain (lupus cerebritis) or kidney disease (lupus nephritis), plasmapheresis is sometimes used to remove antibodies and other immune substances from the blood to suppress immunity. (livehopelupus.org)
  • Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease. (livehopelupus.org)
  • pregnancy
  • The European League Against Rheumatism (EULAR) has noted that low-dose aspirin in individuals with SLE and antiphospholipid antibodies is potentially useful for primary prevention of thrombosis and pregnancy loss. (livehopelupus.org)