• Mapping the distribution of zero-dose children to assess the performance of vaccine delivery strategies and their relationships with measles incidence in Nigeria. (cdc.gov)
  • We considered COVID-19 vaccines with different profiles and different vaccination strategies such as vaccinating elderly age groups (over 65s) or high-incidence groups, i.e. adults between 20 and 39 years old who have contributed to more than 60% of total COVID-19 cases in the country thus far. (bvsalud.org)
  • For vaccines that block infection, the preferred (cost-effective) strategy was to vaccinate the high incidence group. (bvsalud.org)
  • Meanwhile, COVID-19 vaccines that reduces severity (including hospitalization and mortality) were cost-effective when the elderly were vaccinated, while vaccinating the high-incidence group was not cost-effective with this vaccine type. (bvsalud.org)
  • CONCLUSION: COVID-19 vaccines are good value for money even in a relatively low-incidence and low-mortality setting such as Thailand, if the appropriate groups are vaccinated. (bvsalud.org)
  • Impact and effectiveness against vaccine-type invasive pneumococcal disease, radiological pneumonia and rotavirus gastroenteritis are investigated using before-after incidence comparisons and case-control designs, respectively. (ox.ac.uk)
  • In the context of multiple population level interventions targeting study endpoints attribution of reduced incidence to vaccine impact may be flawed. (ox.ac.uk)
  • Welcome declines in disease incidence and in child mortality make accrual of required sample sizes difficult, necessitating large studies to detect the relatively small but potentially significant contribution of vaccines to mortality prevention. (ox.ac.uk)
  • doi: 10.1016/j.vaccine.2022.07.024. (cdc.gov)
  • doi: 10.1016/j.vaccine.2022.03.002. (cdc.gov)
  • doi: 10.1016/j.vaccine.2022.11.026. (cdc.gov)
  • doi: 10.1016/j.vaccine.2020.05.003. (cdc.gov)
  • At the conclusion of the DOMI program, IVI synthesized the diverse epidemiological, clinical, economic, and behavioral findings of these studies in order to facilitate informed decision-making by policymakers at the national level on the use of vaccines against the diseases targeted by DOMI. (wikipedia.org)
  • We describe platform characteristics including strengths and weaknesses for conducting vaccine evaluations.DiscussionIntegrating data from individual level and ecological methods across multiple sites provides comprehensive information for policymakers on programme impact and vaccine effectiveness including changes in serotype/genotype distribution over time. (ox.ac.uk)
  • Regardless of vaccine type, higher vaccination coverage, higher efficacy, and longer protection duration were always preferred. (bvsalud.org)
  • Methods and challenges in measuring the impact of national pneumococcal and rotavirus vaccine introduction on morbidity and mortality in Malawi. (ox.ac.uk)
  • BackgroundPneumonia and gastroenteritis are leading causes of vaccine-preventable childhood morbidity and mortality. (ox.ac.uk)
  • Qualitative assessment of caregiver experiences when navigating childhood immunisation in urban communities in Sierra Leone. (cdc.gov)
  • Maternal knowledge, attitude, and perception about childhood routine immunization program in Atakumosa-west local government area, Osun State, southwestern Nigeria. (cdc.gov)
  • Routine cross-notification between the veterinary and human health surveillance systems should be part of any zoonotic disease prevention and control programme, and close collaboration between the two health sectors is particularly important during epidemiological and outbreak investigations. (who.int)
  • Working in collaboration with the international scientific community, public health organizations, governments, and industry, IVI is involved in all areas of the vaccine spectrum - from new vaccine design in the laboratory to vaccine development and evaluation in the field to facilitating sustainable introduction of vaccines in countries where they are most needed. (wikipedia.org)
  • Head-to-head comparison of the immunogenicity of RotaTeq and Rotarix rotavirus vaccines and factors associated with seroresponse in infants in Bangladesh: A randomised, controlled, open-label, parallel, phase 4 trial. (cdc.gov)
  • In observational non-randomised designs ascertainment of vaccine status may be biased particularly in infants with fatal outcomes. (ox.ac.uk)
  • For the past few years much of my lab's work has focused on autism, including an evaluation of the possible contribution of thimerosal, the ethylmercury-containing vaccine preservative. (vaccineriskawareness.com)
  • At the time of the analysis, there was uncertainty about the precise characteristics of the vaccines available, in terms of their potential impact on transmission and reductions to the severity of infection. (bvsalud.org)
  • These analyses helped to inform the vaccination strategy in Thailand throughout 2021 and can inform future modelling studies for policymaking when the characteristics of vaccines are uncertain. (bvsalud.org)
  • OBJECTIVE: This study aimed to assess the cost-effectiveness of COVID-19 vaccines, preferred COVID-19 vaccine profiles, and the preferred vaccination strategies in Thailand. (bvsalud.org)
  • citation needed] IVI's first major initiative, Diseases of the Most Impoverished (DOMI), was a program of research and technical assistance to accelerate the introduction of new vaccines against typhoid fever, cholera, and shigellosis into public health programs for the poor in developing countries. (wikipedia.org)
  • The use of adaptive sampling to reach disadvantaged populations for immunization programs and assessments: A systematic review. (cdc.gov)
  • The institute has a unique mandate to work exclusively on vaccine development and introduction specifically for people in developing countries, with a focus on neglected diseases affecting these regions. (wikipedia.org)
  • Modeling the impact of vaccination for the Immunization Agenda 2030: Deaths averted due to vaccination against 14 pathogens in 194 countries from 2021-2030. (cdc.gov)
  • Evaluating their effectiveness is vital to ensure optimal implementation and justify sustained investment.Methods/designA national evaluation platform was established to determine vaccine effectiveness and impact in Malawi. (ox.ac.uk)
  • Careful evaluation of vaccine effectiveness and impact in such settings is critical to sustaining support for vaccine programmes. (ox.ac.uk)
  • RESULTS: COVID-19 vaccines that block infection combined with social distancing were cost-saving regardless of the target population compared to social distancing alone (with no vaccination). (bvsalud.org)
  • Comprehensive vaccine-preventable disease surveillance in the Western Pacific Region: A literature review on integration of surveillance functions, 2000-2021. (cdc.gov)
  • A global comprehensive vaccine-preventable disease surveillance strategy for the immunization agenda 2030. (cdc.gov)
  • A separate 1,300m² pilot plant facility, intended for the production of test lots of vaccines for training and evaluation purposes, was constructed but never completed due to a lack of funding. (wikipedia.org)
  • Life-saving Instruction for Emergences (LIFE), a virtual reality (VR) medical training platform developed by doctors, nurses and researchers at the KEMRI-Wellcome Trust Research Programme (KWTRP) in Kenya and Oxford University with support from HTC, has officially launched today. (ox.ac.uk)
  • The International Vaccine Institute (IVI) is an independent, nonprofit, international organization founded on the belief that the health of children in developing countries can be dramatically improved by the use of new and improved vaccines. (wikipedia.org)
  • In 1992, Dr. Seung-Il Shin, then Senior Health Advisor for the United Nations Development Programme (UNDP), initiated a study to explore the feasibility of establishing an international institute devoted to vaccine research and development within the framework of the Children's Vaccine Initiative (CVI). (wikipedia.org)
  • citation needed] Based on the results of Shin's feasibility study, in 1993 the UNDP adopted a formal proposal to establish the International Vaccine Institute (IVI). (wikipedia.org)
  • Control of anthrax among humans depends on the integration of veterinary and human health surveillance and control programmes. (who.int)
  • These scientific publications are authored or co-authored by CDC scientists and/or funded by CDC's Global Immunization Division, Center for Global Health. (cdc.gov)
  • Created initially as an initiative of the UN Development Programme (UNDP), IVI began formal operations as an independent international organization in 1997 in Seoul, Republic of Korea. (wikipedia.org)
  • Routine cross-notification between the veterinary and human health surveillance systems should be part of any zoonotic disease prevention and control programme, and close collaboration between the two health sectors is particularly important during epidemiological and outbreak investigations. (who.int)
  • New malaria chemoprevention and vaccine initiatives target young children attending routine immunisation services. (ox.ac.uk)
  • Within days of the PM's decision came even better news - that the first interim results of the Phase III clinical trials showed 81 per cent efficacy of their vaccine! (businessindia.co)
  • Conclusions Targeting chemoprevention or vaccination programmes to areas where community-based parasite prevalence is ≥10% is likely to match the age ranges covered by interventions (e.g. intermittent presumptive treatment in infancy to children aged 2-23 months and current vaccine age eligibility and duration of efficacy) and the age ranges of highest disease burden. (ox.ac.uk)
  • In 1992, Dr. Seung-Il Shin, then Senior Health Advisor for the United Nations Development Programme (UNDP), initiated a study to explore the feasibility of establishing an international institute devoted to vaccine research and development within the framework of the Children's Vaccine Initiative (CVI). (wikipedia.org)
  • citation needed] IVI's first major initiative, Diseases of the Most Impoverished (DOMI), was a program of research and technical assistance to accelerate the introduction of new vaccines against typhoid fever, cholera, and shigellosis into public health programs for the poor in developing countries. (wikipedia.org)
  • Over the years, social scientists have developed a programme of empirical work on research ethics. (ox.ac.uk)
  • The institute has a unique mandate to work exclusively on vaccine development and introduction specifically for people in developing countries, with a focus on neglected diseases affecting these regions. (wikipedia.org)
  • In moderate and high transmission settings, 34% and 42% of the children were aged between 2 and 23 months and so within the age range targeted by chemoprevention or vaccines. (ox.ac.uk)
  • A separate 1,300m² pilot plant facility, intended for the production of test lots of vaccines for training and evaluation purposes, was constructed but never completed due to a lack of funding. (wikipedia.org)
  • It was in these hospitals that volunteers were recruited and given the vaccine (or a placebo, for comparison purposes). (businessindia.co)