Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous lowered white blood cell count (leukopenia, most commonly of neutrophils) and thus causing neutropenia in the circulating blood. (wikipedia.org)
To be precise, neutropenia is the term normally used to describe absolute neutrophil counts (ANCs) of less than 500 cells per microlitre, whereas agranulocytosis is reserved for cases with ANCs of less than 100 cells per microlitre. (wikipedia.org)
List medications that can cause neutropenia and thrombocytopenia, and state drugs that are useful for neutropenia. (ashp.org)
Approximately 1 month into his hospital stay, the patient developed severe isolated neutropenia. (journalmc.org)
Many medications have been implicated as causal agents of neutropenia, but only one case has been reported describing isolated neutropenia induced by amiodarone [ 18 ]. (journalmc.org)
Granulocytopenia3
for these reasons, granulocytopenia is a more etymologically consistent term, and as such, is sometimes preferred to "agranulocytosis" (which can be misinterpreted as "agranulocyt-osis", meaning proliferation of agranulocytes (i.e. lymphocytes and monocytes). (wikipedia.org)
Agranulocytosis implies a more severe deficiency than granulocytopenia. (wikipedia.org)
Immune thrombocytopenia (ITP) is the most common autoimmune cytopenia. (efim.org)
Furthermore, amiodarone can induce immunological manifestations such as anti-amiodarone antibodies, lupus-like syndrome, immune-mediated thrombocytopenia, Coombs-positive hemolytic anemia (in canines), and vasculitis [ 12 - 17 ]. (journalmc.org)
Acute1
Prior studies reported high guideline adherence for secondary prevention medications (SPM) at hospital discharge in patients with acute myocardial infarction (AMI). (efim.org)
Clinically2
Agranulocytosis may be asymptomatic, or may clinically present with sudden fever, rigors and sore throat. (wikipedia.org)
In patients with clinically and biologically controlled disease, we aimed to assess how. (efim.org)
System2
People with this condition are at very high risk of serious infections due to their suppressed immune system. (wikipedia.org)
13 Claas F H, Abbott P A, Witvliet M D, D'Amaro J, Barnes P M, Krupp P. No direct clinical relevance of the human leucocyte antigen (HLA) system in clozapine-induced agranulocytosis. (thieme-connect.de)
Blood3
In agranulocytosis, the concentration of granulocytes (a major class of white blood cells that includes neutrophils, basophils, and eosinophils) drops below 200 cells/mm3 of blood. (wikipedia.org)
a blood test used to measure the degree of anticoagulation in a patient taking warfarin. (ashp.org)
7 Hummer M, Kurz M, Barnas C, Saria A, Fleischhacker W W. Clozapine-induced transient white blood count disorders. (thieme-connect.de)
Class1
The development of modern second generation antipsychotics such as olanzapine, risperidone, quetiapine, amisulpride, ziprasidone or aripiprazol, however, makes it possible to use the positive effects of this class of drugs without the risks of a clozapine treatment. (thieme-connect.de)