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  • recombinant protein
  • If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production , custom recombinant protein production or custom antibody production . (mybiosource.com)
  • Small volumes of UL123 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. (mybiosource.com)
  • microRNA
  • DALLAS "" June 12, 2005 "" Researchers at UT Southwestern Medical Center have discovered how a small molecule of RNA called microRNA "" a chemical cousin of DNA "" helps fine tune the production of a key protein involved in the early development of heart muscle. (redorbit.com)
  • The microRNA turns off production of the Hand2 protein at precisely the right time to allow the proper development of heart muscle. (redorbit.com)
  • The finding that this microRNA controls Hand2, and probably several other proteins, is very significant. (redorbit.com)
  • You can imagine a pool of messenger RNA ready to make a protein, and by virtue of a microRNA, that protein synthesis can immediately be shut off and turned back on based on a cell's environment or its needs at the time. (redorbit.com)
  • embryonic
  • We think that Hand2 is necessary in the early stages of embryonic development to allow proliferation and expansion of a pool of muscle progenitor cells that can eventually develop into the heart," said Dr. Deepak Srivastava, senior author of the paper. (redorbit.com)
  • This led them to focus on a protein called maternal embryonic leucine-zipper kinase (MELK). (eurekalert.org)
  • complementary
  • Three striking features are revealed: (i) the codons providing the most stable codon-anticodon interactions appear first, (ii) the new codons appear simultaneously with their complementary counterparts, and (iii) the new codons are lowest cost derivatives of the codons acquired earlier - by mutations in the third position, and by complementary copying. (jbsdonline.com)
  • zinc
  • the interaction enhances ATF7 -mediated viral transactivation activity which requires the zinc binding domains of both proteins (By similarity). (rcsb.org)
  • p>This subsection of the 'Function' section specifies the position(s) and type(s) of zinc fingers within the protein. (uniprot.org)
  • antibody
  • Lelièvre, Knowles and their team used an antibody attached to a fluorescent molecule that targeted and linked with a specific nuclear protein from mammary tissue. (medgadget.com)
  • Thus, sites that can change with little or no impact on relative fitness may have evolved as an immune evasion mechanism to facilitate rapid and early escape from Env-specific antibody. (harvard.edu)
  • They then selected the final four predictive proteins - leptin, prolactin, osteopontin, and insulin-like growth factor II - because each can be measured with off-the-shelf ELISA antibody tests. (medpagetoday.com)
  • evaluations
  • Striking in their evaluations: A large number of these proteins are associated with lipid metabolism. (eurekalert.org)
  • Study participants in these evaluations were substantially older at baseline than in our study, precluding the ability to specifically evaluate risk for early menopause," they note. (medicalnewstoday.com)
  • Growth
  • An early growth response transcription factor that has been implicated in regulation of CELL PROLIFERATION and APOPTOSIS. (curehunter.com)
  • In autoantibody-positive children, it was furthermore possible to reach a better estimate of the speed of the diabetes development using the peptide concentrations of three proteins (hepatocyte growth factor activator, complement factor H and ceruloplasmin) in combination with the age of the particular child. (eurekalert.org)
  • Yale
  • The test has a positive predictive value of 95%, investigators at Yale, George Washington University, and the Nevada Cancer Institute reported in the May 10 early online edition of the Proceedings of the National Academy of Sciences . (medpagetoday.com)
  • Early diagnosis can help prolong or save lives, but clinicians currently have no sensitive screening method because the disease shows few symptoms," said the study's lead author, Gil Mor, M.D., of Yale. (medpagetoday.com)
  • Buhimschi said that the Yale team s work might lead to earlier identification of EONS, so that only babies who need treatment receive antibiotics. (webwire.com)
  • significantly
  • For these, a protein intake level of ≥1.2 g/kg was significantly associated with lower mortality (OR 0.42, 95%CI 0.21 to 0.83, P = 0.013). (hva.nl)
  • Researchers have concluded that for women who eat between three and four servings of vegetable protein each day, their risk of experiencing early menopause is significantly reduced. (medicalnewstoday.com)
  • onset
  • The poor outcome is not entirely dependent on their gestational age at birth but rather on other processes such as early onset neonatal sepsis. (webwire.com)
  • We found that early onset neonatal sepsis is characterized by a variety of biomarkers that have different functions, said Buhimschi. (webwire.com)
  • The detailed food questionnaires filled in by the participants allowed the researchers to look at food and beverage consumption over the period prior to onset of early menopause. (medicalnewstoday.com)
  • regulates
  • Shortly after HIV-1 entry, MELK produced by the target cell regulates removal of the protein coat (the capsid, CA, which is an important part of the core of the virus). (eurekalert.org)
  • stages
  • Our results reveal a previously unrecognized mechanism involved in removal of the protein coat of HIV-1 and contribute to our understanding of the early stages of the viral life-cycle," corresponding authors Hiroaki Takeuchi and Shoji Yamaoka say. (eurekalert.org)
  • Dietary
  • Dietary factors during early life program bone formation in female rats. (eurekalert.org)
  • Reduction of dietary protein has been used to slow down renal disease progression, but patients are often unwilling to make these dietary changes. (clinicaltrials.gov)
  • interaction
  • Interaction with RBX1 and CUL1 inhibits ubiquitination of the proteins targeted by SCF( FBXW7 ) ubiquitin ligase complex, and may be linked to unregulated host cell proliferation. (rcsb.org)
  • this interaction stimulates the acetylation of RB1 by recruiting EP300 and RB1 into a multimeric-protein complex (PubMed:11433299). (rcsb.org)
  • Scientists
  • This also is the first time that scientists have used an animal model to show concrete evidence of a protective effect of an early-life soy protein isolate diet on adult bone loss. (eurekalert.org)
  • The findings, available in the online edition of the journal Nature, may aid scientists in their understanding of how a progenitor cell, or stem cell, decides to become a heart cell, as well as offer researchers a way to predict how other microRNAs in the body control the production of important proteins. (redorbit.com)
  • Scientists believe microRNAs seek out and bind to mRNA, fine tuning the amount of protein that mRNAs manufacture. (redorbit.com)
  • The ability to see the protein patterns in the nucleus gives scientists one more tool in advancing the identification of types of cancer and appropriate treatment, Lelièvre said. (medgadget.com)
  • target
  • these interactions inhibit RBX1 - CUL1 -dependent elongation reaction of ubiquitin chains and attenuate ubiquitination of SCF( FBXW7 ) target proteins (PubMed:19679664). (rcsb.org)
  • a href='/help/protein_existence' target='_top'>More. (uniprot.org)
  • The identification of a potential early warning signal and a possible therapeutic target for the disease could lead to improved survival rates. (rxpgnews.com)
  • Different
  • p>When browsing through different UniProt proteins, you can use the 'basket' to save them, so that you can back to find or analyse them later. (uniprot.org)