• Cinchona Alkaloid Amide Catalyzed Enantioselective Formal [2+ycloadditions of Allenoates and Imines Synthesis of 2 4-Disubstituted Azetidines. (docme.ru)
  • In connection with our ongoing project that deals with the catalytic potential of the cinchona-alkaloid-derived amides,[17-we became interested in examining the reaction of allenoates with imines in the presence of a chiral tertiary amine catalyst. (docme.ru)
  • The equilibrium in this reaction usually favors the carbonyl compound and amine, so that azeotropic distillation or use of a dehydrating agent, such as molecular sieves or magnesium sulfate , is required to push the reaction in favor of imine formation. (wikipedia.org)
  • Imines are susceptible to hydrolysis to the corresponding amine and carbonyl compound. (wikipedia.org)
  • We have investigated different aromatic amine and imine compounds for neuroprotective antioxidant functions in cell culture, and found that these compounds possess excellent cytoprotective potential in diverse paradigms of oxidative neuronal cell death, including clonal cell lines, primary cerebellar neurons, and organotypic hippocampal slice cultures. (uni-muenchen.de)
  • The imine is formed when a ketone or aldehyde (24) reacts with an amine (25) to form a dipolar intermediate (26). (wikispaces.com)
  • with imines having an α-hydrogen at the N-alkyl substituent, which is in accordance with a mechanism involving a ruthenium-amine intermediate. (diva-portal.org)
  • New surface hydroxylated and internally quaternised poly(propylene imine) dendrimers as efficient biocompatible drug carriers of norfloxacin. (nih.gov)
  • This study intended to describe the development of two novel, biocompatible and potential surface hydroxylated quaternary ammonium chloride based poly(propylene imine) (PPI) dendrimers for effective delivery of the drug Norfloxacin (NFN). (nih.gov)
  • For this purpose, a multifunctional dendrimeric system derived from diaminobutane poly(propylene imine) dendrimers (DAB) is prepared bearing at its external surface poly(ethylene glycol) chains and guanidinium moieties. (sigmaaldrich.com)
  • These quinone imines are of toxicological significance since N-acetyl-p-benzoquinone imine is a postulated reactive intermediate formed during metabolism of the analgesic drug acetaminophen 1 while 4-(ethoxyphenyl)-p-benzoquinone imine is a possible reactive intermediate formed during metabolism of the analgesic phenacetin 2 . (springer.com)
  • In terms of mechanism, such reactions proceed via the nucleophilic addition giving a hemiaminal -C(OH)(NHR)- intermediate, followed by an elimination of water to yield the imine (see alkylimino-de-oxo-bisubstitution for a detailed mechanism). (wikipedia.org)
  • C(Ph)C 6 H 4 ) 10 provide support for a proposed mechanism involving a intermediate containing a Ru-bound metallated aryl-imine fragment. (rsc.org)
  • There have been published attempts of the creating of an imine between phenylacetaldehyde and t-butylamine ( Verhe 1980 ) in CCl4. (blogspot.com)
  • One way of naming aldimines is to take the name of the radical, remove final "e", and add "-imine", for example ethanimine . (wikipedia.org)
  • Ge, X., Qian, C., Chen, Y.B. and Chen, X.Z. (2014) Novel Carbohydrate-Derived Pyridinecarboxylic Organocatalysts for the Enantioselective Reduction of Imines with Trichlo-rosilane. (oalib.com)
  • M. Moore, H. Thor, G. Moore, S. Nelson, P. Moldéus, and S. Orrenius, The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine (NAPQI) in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca 2+ . (springer.com)
  • An imine ( / ɪ ˈ m iː n / or / ˈ ɪ m ɪ n / ) is a functional group or chemical compound containing a carbon - nitrogen double bond . (wikipedia.org)
  • The water group leaves to form the iminium ion (29), which then transfers the proton to water to produce the imine (30) (Lee 2003). (wikispaces.com)
  • However, closer inspection of that article reveals that the imine was not characterized and used as a crude product in a subsequent step. (blogspot.com)
  • Figure 4.2 shows the last spectrum taken after 22 hours with mostly imine present. (wikispaces.com)
  • Acid- and salt-triggered multifunctional poly(propylene imine) dendrimer as a prospective drug delivery system. (sigmaaldrich.com)
  • In order to reduce imines with trichlorosilane, the carbohydrate-derived organocatalysts were prepared and screened. (oalib.com)