BenzamidesPiperazinesPyrimidinesLeukemia, Myelogenous, Chronic, BCR-ABL PositiveGastrointestinal Stromal TumorsFusion Proteins, bcr-ablHypersensitivity, DelayedAntineoplastic AgentsProto-Oncogene Proteins c-kitCell Line, TumorProtein Kinase InhibitorsReceptor, Platelet-Derived Growth Factor alphaLeukemia, Myeloid, Chronic-PhaseDrug HypersensitivityReceptor, Platelet-Derived Growth Factor betaDrug Resistance, NeoplasmBlast CrisisHypereosinophilic SyndromeGenes, ablGastrointestinal NeoplasmsProtein-Tyrosine KinasesCytogenetic AnalysisTumor Cells, CulturedK562 CellsHypopigmentationProto-Oncogene Proteins c-ablTreatment OutcomePregnatrienesLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativePhiladelphia ChromosomeTumor Markers, BiologicalCell ProliferationDose-Response Relationship, DrugApoptosisHypersensitivityEnzyme InhibitorsRemission InductionTime FactorsMutationReceptors, Platelet-Derived Growth FactorRNA, MessengerNeoplasms, ExperimentalNeoplasmsMice, Inbred BALB CDermatofibrosarcomaKetonesSignal TransductionTumor Necrosis Factor-alphaTumor BurdenFuransAlveolitis, Extrinsic AllergicMastocytosis, SystemicDrug ApprovalNeoplasm MetastasisReverse Transcriptase Polymerase Chain ReactionCell DivisionCell SurvivalDisease-Free SurvivalFibromatosis, AggressiveImmunohistochemistryDermatitis, ContactNeoplasm ProteinsPhosphorylationMice, NudeBrain NeoplasmsThiazolesDisease ProgressionDrug SynergismCells, CulturedProto-Oncogene Proteins c-sisAdministration, OralXenograft Model Antitumor AssaysSurvival AnalysisGene Expression Regulation, NeoplasticCell LineBlotting, WesternPrognosisDentin SensitivityMice, Inbred C57BLAntineoplastic Combined Chemotherapy ProtocolsMice, SCIDSkin TestsNeoplastic Stem CellsSkinHarringtoninesLeukemia, Myeloid, Accelerated PhaseSurvival RateHypersensitivity, ImmediateNeoplasm, ResidualDrug Administration ScheduleTumor Suppressor Protein p53PyrrolesInterferon-alphaNeoplasm TransplantationDisease Models, AnimalCombined Modality TherapyIn Situ Hybridization, FluorescenceCarcinoma, Ehrlich TumorSkin NeoplasmsFlow Cytometry