Imaging most radionuclides. Medical search. Frequent questions

The Trace 'n Treat Training network (Oct 2012 - Oct 2016) has fulfilled the very ambitious goal to train young researchers in the field of nuclear diagnostics and radionuclide therapy by bringing together disciplines that cover the entire health care cycle, from prevention to treatment. (europa.eu)
The research objectives of this project were: production of radionuclides with the most appropriate properties for molecular imaging and/or radionuclide therapy, their incorporation in newly designed molecular and supramolecular carriers and finally their pre-clinical evaluation and comparison. (europa.eu)
Diagnostic Imaging and Radionuclide Therapy. (avmi.net)
Peptide receptor radionuclide therapy (PRRT) is a type of radionuclide therapy, using a radiopharmaceutical that targets peptide receptors to deliver localised treatment, typically for neuroendocrine tumours (NETs). (wikipedia.org)
For radiological diagnosis and radionuclide therapy, X-ray and gamma-ray imaging technologies are essential. (elsevierpure.com)
Radionuclide therapy is also rapidly developing with the use of these modalities. (elsevierpure.com)
We compared the efficacy of radionuclide therapy with 111 In-pentetreotide and 131 I-metaiodobenzylguanidine (MIBG) in 20 patients (group A) with the outcome of similar patients who could not be treated for nonmedical reasons (group B, n = 12). (snmjournals.org)
Radionuclide therapy was beneficial in 14 patients (73% of group A), with only 1 significant side effect. (snmjournals.org)
The overall Kaplan-Meier survival rate and cumulative progression-free and cumulative event-free survival rates during the first 15 mo were significantly higher in patients receiving radionuclide therapy ( P = 0.019, P = 0.024, and P = 0.019, respectively). (snmjournals.org)
Radionuclide therapy is feasible and safe and significantly defers the occurrence of fatal and nonfatal events in patients clinically uncontrolled by conventional therapy. (snmjournals.org)
Consequently, radionuclide therapy may be proposed to patients with uncontrolled disease after conventional therapy ( 5 , 11 ). (snmjournals.org)
In France, 131 I-MIBG can be used for radionuclide therapy. (snmjournals.org)
Octreotide labeling with 90 Y has recently been proposed for radionuclide therapy ( 12 - 16 ) but, to date, it is not commercially available in France. (snmjournals.org)
Because 111 In emits short-range electrons that can have significant biologic effects at a cellular level ( 17 - 19 ), radionuclide therapy with a high activity of 111 In-pentetreotide has been used in a few patients with GEP tumors ( 5 , 20 - 30 ). (snmjournals.org)
To our knowledge, there are no randomized controlled trials with radionuclide therapy in GEP tumors. (snmjournals.org)
We report the results of radionuclide therapy with either 111 In-pentetreotide or 131 I-MIBG in a population of patients with advanced-stage GEP tumors. (snmjournals.org)
With the growing use of 177 Lu-DOTATATE peptide receptor radionuclide therapy (PRRT), there are many unanswered questions regarding patient selection. (snmjournals.org)
In this review, we will discuss the characteristics of molecular imaging, the novel imaging agent including targeted imaging agent and multifunctional imaging agent, as well as cite some examples of their application in molecular imaging and therapy. (hindawi.com)
A lot of preclinical and clinical studies have confirmed the feasibility of using radionuclide molecular imaging to detect tumor and predict response to therapy [ 12 , 13 ]. (hindawi.com)
The Society of Nuclear Medicine and Molecular Imaging has released a consensus statement that provides standardized guidance for the selection and management of metastatic castrate-resistant prostate cancer (mCRPC) patients being treated with 177 Lu-PSMA radionuclide therapy. (appliedradiology.com)
The statement also reviews current clinical struggles physicians face during treatment with 177 Lu-PSMA-617 radionuclide therapy. (appliedradiology.com)
To develop the patient selection criteria and determine appropriate use scenarios, SNMMI assembled an autonomous workgroup to represent a multidisciplinary panel of health care providers with substantive knowledge in the use of nuclear medicine in 177 Lu-PSMA-617 radionuclide therapy. (appliedradiology.com)
Furthermore, the consensus statement addressed current clinical struggles that physicians face when administering 177 Lu-PSMA-617 radionuclide therapy. (appliedradiology.com)
We look forward to the potential use of PSMA radionuclide therapy in pre-chemotherapy mCRPC or other settings pending the full results of ongoing trials," noted the authors. (appliedradiology.com)
This study considers the error distributions for time-integrated activity (TIA) of single-time-point (STP) methods for patient-specific dosimetry in radionuclide therapy. (lu.se)
The general case with the same pharmaceutical labelled with different radionuclides for imaging and therapy are considered for a mono-exponential time-activity curve. (lu.se)
This characteristic makes it suitable for applications in molecular imaging or radionuclide targeted therapy. (bvsalud.org)
The first four are positron emitters for imaging, and the last one Cu-67 is a ß--emitting radionuclide suitable for targeted therapy. (bvsalud.org)

Radionuclide imaging can expose patients to similar amounts of radiation than do comparable computed tomography (CT) studies. (msdmanuals.com)
There are five imaging modalities available for molecular imaging, including X-ray computed tomography imaging (CT), optical imaging (OI), radionuclide imaging (involving PET and SPECT), ultrasound (US) imaging and magnetic resonance imaging (MRI) [ 9 ]. (hindawi.com)
Medical imaging tests, such as computed tomography (CT) scans. (cancer.gov)
My research focuses on the development of novel radiotracers for positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging. (nottingham.ac.uk)
The guideline will provide a review of diagnostic modalities for patients with small bowel hemorrhage including VCE, endoscopic evaluation with push and/or deep enteroscopy, and radiographic modalities including cross-sectional imaging (computed tomography (CT) and magnetic resonance (MR)) enterography, angiography, and scintigraphy. (medscape.com)

SPECT, which uses a rotating camera system and tomographic reconstruction to produce a 3-dimensional image, is more common in the United States. (msdmanuals.com)
With multihead SPECT systems, imaging can often be completed in ≤ 10 minutes. (msdmanuals.com)
It is injected at peak stress and imaged with SPECT, followed 4 hours later by injection of half the original dose during rest and by repeat SPECT. (msdmanuals.com)
Extraosseous findings on bone scintigraphy using fusion SPECT/CT and correlative imaging. (tsnmjournals.org)
The paper "EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT/CT: 2015 revision" has restricted access. (cnr.it)
Radionuclide molecular imaging including PET and SPECT is the earliest and most mature molecular imaging technique. (hindawi.com)
PET and SPECT are whole body imaging techniques that use trace quantities of radioisotope-tagged bioactive molecules to probe biological function. (nottingham.ac.uk)

A special camera takes images that show how the radioactive materials travel with the cerebrospinal fluid (CSF) through the spine. (medlineplus.gov)
Radionuclide imaging uses a special detector (gamma camera) to create an image following injection of radioactive material. (msdmanuals.com)
Nevertheless, a limited number of radioactive tracers are imaged owing to the limitations of the imaging devices. (elsevierpure.com)
A radionuclide ( radioactive nuclide , radioisotope or radioactive isotope ) is a nuclide that has excess nuclear energy, making it unstable. (wikipedia.org)
During those processes, the radionuclide is said to undergo radioactive decay . (wikipedia.org)
The radioactive decay can produce a stable nuclide or will sometimes produce a new unstable radionuclide which may undergo further decay. (wikipedia.org)
An imaging tracer made with radionuclides is called a radioactive tracer . (wikipedia.org)
A nuclear imaging technique that uses a very small amount of radioactive material, which is injected into the bloodstream to be detected by a scanner. (hopkinsmedicine.org)
This imaging test uses a very small amount of radioactive material. (massgeneral.org)
A small amount of a radioactive chemical (radionuclide) is injected into a vein or swallowed. (cancer.gov)
Half-life is the length of time it takes for half of the radioactive atoms of a specific radionuclide to decay. (cdc.gov)
Depending on the radionuclide, this process could be fast or take a very long time - radioactive half-lives can range from milliseconds to hours, days, sometimes millions of years. (cdc.gov)

A key advantage of PRRT over other methods of radiotherapy is the ability to target delivery of therapeutic radionuclides directly to the tumour or target site. (wikipedia.org)
In this webinar, I will discuss charged particle, neutron and photonuclear reactions used to produce therapeutic radionuclides of interest. (wmis.org)

After acute myocardial infarction, myocardial perfusion imaging can help estimate prognosis because it can show extent of the perfusion abnormality due to acute myocardial infarction, extent of scarring due to previous infarcts, and residual peri-infarct or other areas of reversible ischemia. (msdmanuals.com)

Also may occur with other primary malignancies, which can cause confusion with the metastasis in whole body bone scan (WBBS) imaging. (tsnmjournals.org)
Radionuclide bone scan. (hopkinsmedicine.org)
Breast cancer may be evaluated using the nuclear bone scan as an imaging modality. (bvsalud.org)

Diagnostic radiology : an Anglo-American textbook of imaging / edited by Ronald G. Grainger, David J. Allison. (who.int)
Rational use of diagnostic imaging in paediatrics : report of a WHO study group [meeting held in Geneva from 18 to 25 November 1985]. (who.int)
In addition, the imaging of Ga-67 and In-111, which are used in various diagnostic scenarios, was conducted. (elsevierpure.com)
This Atlas will allow professionals interested in non-FDG PET/CT imaging to embrace the variety of oncological imaging by providing clinically relevant teaching files on the effectiveness and diagnostic quality of non-FDG-PET/CT imaging in routine applications. (iaea.org)
Magnetic resonance imaging is a diagnostic imaging modality that is capable of demonstrating a wide variety of soft-tissue lesions with contrast resolution equal or superior to CT scanning in various parts of the body. (cms.gov)
A diagnostic test that produces images of internal tissues, bones, and organs onto film. (hopkinsmedicine.org)
A diagnostic procedure that uses a combination of large magnets, radiofrequencies, and a computer to produce detailed images of organs and structures within the body. (hopkinsmedicine.org)

Radionuclide tracer techniques in haematology / C. S. Bowring. (who.int)
We also verified that the 3D distribution of the At-211 tracer inside a mouse could be imaged using the pinhole mode. (elsevierpure.com)

Abstract: Targeted radiotherapy is a form of nuclear medicine where a radionuclide, with desirable decay properties (such as the emission of an alpha, beta or Auger electron), is attached to a targeting vector that is highly specific for receptors that are over expressed on diseased cells. (wmis.org)
The CDFs are used for determining 95% coverage intervals of the relative errors for different combinations of imaging time points, physical decay constants, and relative standard deviations of the biological decay constant. (lu.se)

A great deal of research has brought about improved prostate imaging modalities. (baptisthealth.net)
Advances in imaging modalities in prostate cancer. (baptisthealth.net)
In this study, we developed a system that simultaneously realizes three modalities: Compton, pinhole, and PET imaging in 3D space using multiple hybrid Compton cameras. (elsevierpure.com)

the radionuclide, chelator, and somatostatin analogue (peptide). (wikipedia.org)
The chelator is the essential link between the radionuclide and peptide. (wikipedia.org)

A pharmaceutical drug made with radionuclides is called a radiopharmaceutical . (wikipedia.org)

This test uses large magnets, radio waves, and a computer to make detailed images of organs and structures in the body. (massgeneral.org)

A radionuclide cisternogram is a nuclear scan test. (medlineplus.gov)
Tc-99m radionuclide scan was proven to be a useful tool, enabling distinction between the two processes. (tau.ac.il)
Radionuclide or radioiodine scan. (rochester.edu)
A radionuclide cystogram is a special imaging nuclear scan test. (mountsinai.org)

Copper has several clinically relevant radioisotopes and versatile coordination chemistry, allowing attachment of its radionuclides to biological molecules. (bvsalud.org)

A contrast agent is often either put in a vein or swallowed to help make the detailed images clearer. (rochester.edu)

This test uses energy beams to make images of internal tissues, bones, and organs onto film. (massgeneral.org)

Facility for radionuclide production and radiochemistry for pre-clinical applications. (kcl.ac.uk)
Recent projects include development of new radiotracers for imaging bacterial infection, hypoxia imaging in cancer patients using 18 F-HX4 (OXYPET Trial), development of new fluorine-18 labelled molecules for protein synthesis imaging, and various early stage radiochemistry projects using fluorine-18, zirconium-89 and technetium-99m. (nottingham.ac.uk)
My background is in radiochemistry and synthetic chemistry, and more recently CTIMP imaging trials. (nottingham.ac.uk)

Imaging bone metastases in breast cancer: techniques and recommendations for diagnosis. (tsnmjournals.org)
Imaging plays an important role in the prenatal and postnatal diagnosis of anomalies associated with Down syndrome. (medscape.com)
However, radionuclides with suitable properties are used in nuclear medicine for both diagnosis and treatment. (wikipedia.org)
This should facilitate the interpretation of images to support accurate diagnosis. (iaea.org)
Therefore, molecular imaging plays an important role in earlier detection, accurate diagnosis, and drug development and discovery [ 5 - 7 ]. (hindawi.com)
Used with organs and regions for ultrasonic imaging and with diseases for ultrasonic diagnosis. (bvsalud.org)
Used for radionuclide imaging of any anatomical structure, or for the diagnosis of disease. (bvsalud.org)

this public health assessment evaluates radionuclides released to White Oak Creek that traveled off site into the Clinch River and the Lower Watts Bar Reservoir. (cdc.gov)

Uranium is a radionuclide that has an extremely long half-life. (cdc.gov)

CMS received a request to delete the national noncoverage of blood flow measurement from the Magnetic Resonance Imaging NCD at 220.2 of the NCD Manual and thus permit local Medicare contractor discretion to cover this use under 220.2(D). The requestor points to an apparent contradiction between this noncoverage provision and the national coverage of magnetic resonance imaging under the Magnetic Resonance Angiography NCD at 220.3 of the NCD Manual. (cms.gov)

Radionuclide imaging with thallium or technetium is a noninvasive means to identify reversible cardiac ischemia in patients with cardiac cirrhosis in the setting of new or decompensated heart failure. (medscape.com)

Elements heavier than lead , and the elements technetium and promethium , exist only as radionuclides. (wikipedia.org)
For example, technetium-99m, one of the most common medical isotopes used for imaging studies, has a half-life of 6 hours. (cdc.gov)

At least another 60 radionuclides are detectable in nature, either as daughters of primordial radionuclides or as radionuclides produced through natural production on Earth by cosmic radiation. (wikipedia.org)
A machine with a special camera moves over the person lying on a table and detects the type of radiation given off by the radionuclides. (cancer.gov)
Radionuclides can give off more than one kind of radiation, so it's not uncommon to have a radionuclide that gives off both beta and gamma radiation, for example. (cdc.gov)

Results of search for 'su:{Radionuclide imaging. (who.int)

Imaging plays an essential role in prostate cancer clinical management. (baptisthealth.net)
Due to its advantages of high sensitivity and quantifiability, radionuclide molecular imaging plays an important role in clinical and preclinical researches [ 11 ]. (hindawi.com)

PET is the molecular imaging modality most extensively used in current clinic routine. (hindawi.com)
Multi-modality medical imaging enables measurement of the three-dimensional spatial distribution of inhaled, radiolabelled aerosol within the human lung. (uaeu.ac.ae)

abstract = "Tc-99m pertechnetate radionuclide scrotal scanning was performed on nine hospitalized boys with anaphylactoid purpura and acute scrotal tenderness. (tau.ac.il)

Before a radionuclide is ready for use in targeted radiotherapy applications it must first be produced and made available in a radiochemically pure form. (wmis.org)
Clinicians' Guides to Radionuclide Hybrid Imaging PET/CT in Radiotherapy Planning. (nottingham.ac.uk)

Magnetic resonance imaging (MRI, formerly known as nuclear magnetic resonance imaging - NMRI) is a noninvasive method of graphically representing the distribution of water and other hydrogen-rich molecules in the human body. (cms.gov)

Contrast-enhanced CT is the preferred method to image disruption because it has better spatial resolution than radionuclide techniques. (ajnr.org)
variable to be the 'slice' dimension, and any other spatial dimensions are considered to be 'image' dimensions. (wikibooks.org)
SPATIAL RESOLUTION in air for a specified radionuclide excluding the COLLIMATOR 3.19 INTRINSIC ENERGY SPECTRUM measured histogram of pulse heights for the DETECTOR HEAD without COLLIMATOR NOTE The pulse height should be expressed as corresponding energy. (findfreestandards.com)

In the planar images, radiotracer uptake at multiple sites was detected on the anterior side of the skull base and the posterior side of the vertex of the cranium. (tsnmjournals.org)
Automated radiosynthesis and preclinical in vivo evaluation of [18F]Fluoroethylpuromycin as a potential radiotracer for imaging protein synthesis with PET Nuclear Medicine and Biology. (nottingham.ac.uk)

To develop a quantitative method for imaging osmotic blood-brain barrier disruption and to see if iopamidol could be safely given intravenously in conjunction with blood-brain barrier disruption. (ajnr.org)
Visual comparison of stress and delayed images can be supplemented by quantitative displays. (msdmanuals.com)

With the use of the radionuclide gastric-emptying test and a new data processing method, the contraction characteristics of the stomach were analyzed. (nih.gov)

Radionuclides occur naturally or are artificially produced in nuclear reactors , cyclotrons , particle accelerators or radionuclide generators . (wikipedia.org)

METHODS Forty-five blood-brain barrier disruption procedures were imaged with CT and radionuclide scans. (ajnr.org)
Radionuclide bone scans. (massgeneral.org)

Conventional radiography remains the mainstay of imaging in the immediate postnatal period and in the older child with suspected congenital heart disease, infection, GI anomalies, or skeletal anomalies (see the images below). (medscape.com)

The present consensus statement was developed collaboratively by the North American Neuroendocrine Tumor Society (NANETS) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI). (snmjournals.org)
Molecular imaging is an emerging field that integrates advanced imaging technology with cellular and molecular biology. (hindawi.com)
Molecular imaging requires high resolution and high sensitive instruments and specific imaging agents that link the imaging signal with molecular event. (hindawi.com)
Molecular imaging is a rapidly developed multidiscipline which involves molecular biology, chemistry, computer, engineering, and medicine [ 1 ]. (hindawi.com)
Workshop: Molecular Imaging The New and Very New Technology. (bvs.br)

Stress Testing In stress testing, the heart is monitored by electrocardiography (ECG) and often imaging studies during an induced episode of increased cardiac demand so that ischemic areas potentially at risk. (msdmanuals.com)
Body imaging may reveal evidence of cardiac cirrhosis, including hepatomegaly, hepatic congestion, IVC enlargement, and splenomegaly (see following images). (medscape.com)

Various approaches to approve effectiveness and limit side effects are being investigated, including radiosensitising drugs, fractionation regimes and new radionuclides. (wikipedia.org)

Nitroimidazole Conjugates of Bis(thiosemicarbazonato)64Cu(II) - Potential Combination Agents for the PET Imaging of Hypoxia Journal of Inorganic Biochemistry. (nottingham.ac.uk)

This test uses X-rays to get detailed cross-sectional images of the body. (rochester.edu)

Automated Radiosynthesis of GMP Quality [18F]HX4 for PET Imaging of Hypoxia Nuclear Medicine and Biology. (nottingham.ac.uk)

This brief review considers five radionuclides of copper. (bvsalud.org)

With a gamma emitter as the radionuclide, the technique can be used for imaging with a gamma camera or PET scanner to locate tumours. (wikipedia.org)
L'interpretation collegiale etait effectuee apres acquisition et traitement des images obtenues au moyen d'une gamma camera. (bvsalud.org)

Most attention in Down syndrome (trisomy 21)is directed toward imaging to detect gastrointestinal anomalies in the early postnatal period and toward imaging congenital heart disease, which may be present at birth and may remain throughout the patient's lifetime. (medscape.com)
McCune-Albright syndrome (MAS) consists of at least two of the following three features: (1) polyostotic fibrous dysplasia (PFD), (2) café-au-lait skin pigmentation (see the image below), and (3) autonomous endocrine hyperfunction (eg, gonadotropin-independent precocious puberty ). (medscape.com)

After ingestion of a radiolabeled test meal, dynamic images of the stomach were acquired and analyzed to determine the frequency, amplitude, and rate of gastric contractions in healthy subjects. (nih.gov)
This is an imaging test that uses X-rays and a computer to make detailed images of the body. (hopkinsmedicine.org)
To test for incomplete bladder emptying, images may be taken with the bladder full. (mountsinai.org)
This test uses X-rays and a computer to make images (often called slices) of the body. (massgeneral.org)

Brill DR. Radionuclide imaging of nonneoplastic soft tissue disorders. (tsnmjournals.org)

Other chelators known as NOTA (triazacyclononane triacetic acid) and HYNIC (hydrazinonicotinamide) have also been experimented with, albeit more for imaging applications. (wikipedia.org)
Nuclear medicine and related radionuclide applications in developing countries : proceedings of an International Symposium on Nuclear Medicine and Related Medical Applications of Nuclear Techniques in Developing Countries, held in Vienna, 26-30 August 1985 / organized by the International Atomic Energy Agency, in co-operation with the World Health Organization. (who.int)
Furthermore, we will discuss the separation chemistry and quality control considerations that are required to realize these radionuclides for medical applications. (wmis.org)
Therapeutic drug or gene is incorporated into nanoparticles to construct multifunctional imaging agents which allow for theranostic applications. (hindawi.com)

In Vitro and In Vivo Evaluations of a Hydrophilic 64Cu-Bis(thiosemicarbazonato)-glucose Conjugate for Hypoxia Imaging Journal of Nuclear Medicine. (nottingham.ac.uk)

A PET detector surrounding the subject is designed to detect the signal and convert the resulting electrical signal into sinograms that are finally rebuilt into tomographic images. (hindawi.com)
with a specified COLLIMATOR and ENERGY WINDOW , the ratio of the COUNT RATE of the DETECTOR HEAD to the ACTIVITY of a plane source of specific dimensions and containing a specified radionuclide placed perpendicular to and centred on the COLLIMATOR AXIS under specified conditions NOTE See also Figure 2. (findfreestandards.com)

The somatostatin analogue affects biodistribution of the radionuclide, and therefore how effectively any treatment effect can be targeted. (wikipedia.org)
Effective treatment of HV depends on a solid understanding of the anatomy involved (see the images below). (medscape.com)
Hypoxia imaging with [18F]HX4 PET in squamous cell head and neck cancers: a pilot study for integration into treatment planning Nuclear Medicine Communications. (nottingham.ac.uk)
These include the role of androgen receptor-targeted therapies, the role of 223 Ra, treatment-related toxicities, when to consider cessation of treatment, exceptional responders and restarting treatment, and imaging during treatment. (appliedradiology.com)

According to the Melton Valley remedial investigation, no data are available on radionuclides in HFIR pond sediment. (cdc.gov)

Anatomy9

Organisms3

Diseases25

Chemicals and Drugs102

Analytical, Diagnostic and Therapeutic Techniques and Equipment70

Phenomena and Processes29

Disciplines and Occupations6

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture6

Humanities2

Information Science6

Health Care26

Geographicals2

Therapy28

Tomography5

SPECT7

Radioactive12

Therapeutic radionuclides2

Myocardial perfusion1

Bone scan3

Diagnostic7

Tracer2

Decay2

Modalities3

Peptide2

Radiopharmaceutical1

Organs and structures1

Scan4

Clinically1

Vein or swallowed1

Tissues1

Radiochemistry3

Diagnosis7

Assessment1

Uranium1

Angiography1

Thallium1

Technetium2

Radiation3

Search1

Clinical2

Modality2

Abstract1

Radiotherapy2

Magnetic1

Spatial3

Radiotracer2

Quantitative2

Characteristics1

Particle1

Scans2

Radiography1

Molecular5

Cardiac2

Fractionation1

Biochemistry1

Cross-sectional1

Biology1

Considers1

Gamma camera2

Syndrome2

Test4

Disorders1

Applications4

Journal of Nuclear Medicine1

Detector2

Treatment4

Investigation1