• Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1. (thermofisher.com)
  • By putting the IL10 gene into the genetic material of Mammalian cell cell, the Mammalian cell could be used as factories or producers to make the desired IL10 protein for research uses. (cusabio.com)
  • Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human IL10. (thermofisher.com)
  • Positive Control: 293T, human IL10-transfected 293T. (thermofisher.com)
  • May 31, 2012 (Thessaloniki, Greece) - Infants carrying a particular allele of the anti-inflammatory cytokine interleukin 10 ( IL10 ) gene are significantly less likely to develop asthma after acute bronchiolitis than infants carrying other alleles, researchers reported here at the European Society for Paediatric Infectious Diseases 30th Annual Meeting. (medscape.com)
  • IL-10 ELISA Kit allows for the in vitro quantitative determination of IL-10(Interleukin 10)/IL10/IL10A/CSIF/TGIF concentrations in plasma, tissue homogenates and other biological fluids. (medicobio.com)
  • Matrices listed below were spiked with certain level of IL-10(Interleukin 10)/IL10/IL10A/CSIF/TGIF and the recovery rates were calculated by comparing the measured value to the expected amount of IL-10(Interleukin 10)/IL10/IL10A/CSIF/TGIF in samples. (medicobio.com)
  • The linearity of the kit was assayed by testing samples spiked with appropriate concentration of IL-10(Interleukin 10)/IL10/IL10A/CSIF/TGIF and their serial dilutions. (medicobio.com)
  • Moreover, higher expression of IL10 in TH17 cells is found in clinically stable vs. active patients. (usi.ch)
  • However, in children who were homozygous carriers of allele G at position 1082 of IL10 , only 1 of 32 (3.1%) had asthma at 5 to 7 years of age ( P = .04). (medscape.com)
  • Moreover, in preschool aged children, up to 21% of non-G allele carriers of IL10 had asthma, compared with just 10% of allele G carriers. (medscape.com)
  • For this study, the researchers used the same cohort as they had used in their rhinovirus study, this time focusing on the potential association between preschool asthma and the polymorphism of IL10 -1082 G/A, as well as other cytokines, such as IL18 -137 G/C, TLR4 -896 A/G, and IFNG -874 T/A, after bronchiolitis in early infancy. (medscape.com)
  • Bone marrow-derived macrophages were produced from mice lacking IL-10 alone (IL10-def) or mice lacking both IL-10 and the p50/p105 subunit of NF-kB (p50/IL10), and left unstimulated, stimulated with LPS (1 ng/ml) or stimulated with LPS and IL-10 (0.3 ng/ml). (gsea-msigdb.org)
  • We investigated the association between severe malaria and genetic variation of IL10 in Gambian children, as several lines of evidence indicate that IL10 is protective against severe malaria and that IL10 production is genetically determined. (nih.gov)
  • Moreover, an intestinal microbial community enriched in SCFA-producing bacteria sustained the production of IL10 by iNKT cells. (ecco-ibd.eu)
  • Here we describe for the first time the presence of IL10-producing iNKT cells (NKT10 cells) in the intestinal lamina propria of healthy individuals and of Crohn's Disease (CD) patients. (ecco-ibd.eu)
  • Experimental colitis models were performed by adoptive cell transfer of murine splenic naïve CD4+ T cells in the presence or absence of IL10-sufficient or deficient iNKT cells. (ecco-ibd.eu)
  • Finally, IL10- deficient iNKT cells failed to control the pathogenic activity of adoptively transferred CD4+ T cells in an experimental colitis model. (ecco-ibd.eu)
  • These results describe an unprecedent IL10-mediated immunoregulatory role of intestinal iNKT cells in controlling the pathogenic functions of mucosal T-helper subsets and in maintaining the intestinal immune homeostasis. (ecco-ibd.eu)
  • Assessing 15 representative signature genes in patients with multiple sclerosis, we find that TH1/17 cells have elevated expression of CXCR3 and reduced expression of IFNG, CCL3, CLL4, GZMB, and IL10 compared to healthy controls. (usi.ch)