• Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. (abcam.com)
  • Bartkova J, Rejthar A, Bartek J, Kovarik J: Differentiation patterns of testicular germ-cell tumours as revealed by a panel of monoclonal antibodies. (exbio.cz)
  • Moreover, because the RaniPill ® capsule technology is a drug-agnostic delivery platform, RT-111 also represents a broader opportunity to potentially replace other injectable-only monoclonal antibodies and large molecules with an oral alternative. (wivb.com)
  • A much more promising strategy is to use recombinant monoclonal antibodies (mAbs) against influenza and several are currently in clinical development ( 9 - 13 ). (frontiersin.org)
  • Chondrocytes and collagens supplies antibodies that are for research of human proteins.Chondrocytes and collagens supplies other types of Assays as 1.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. (assayspro.com)
  • ArthritoMab™ Arthritis Inducing Antibody Cocktail is a cocktail of 4 arthritogenic monoclonal antibodies to collagen II (CII) used for inducing art. (mdbioproducts.com)
  • ArthritoMab™ Antibody Cocktail is a reformulated cocktail of 4 monoclonal antibodies for the induction of arthritis as an alternative to the widely. (mdbioproducts.com)
  • Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. (abcam.com)
  • METHODS: Monoclonal antibodies (mAbs) against recombinant CD5L were raised by subcutaneous immunization of BALB/c mice. (bvsalud.org)
  • In this work, we evaluated 24 anti-BoNT/B monoclonal antibodies (mAbs) for their ability to inhibit the in vitro activity of BoNT/B1, /B2, /B3, /B4, and /B5 and to extract those toxins. (cdc.gov)
  • The details of the immunogen for this antibody are not available. (creativebiolabs.net)
  • A portion of amino acids 254-323 from the human protein was used as the immunogen for the Aquaporin 4 antibody. (nsjbio.com)
  • This antibody clone is manufactured by Abcam. (abcam.com)
  • Anti-hTLR6-IgG (clone C5C8) is a monoclonal antibody specific for human Toll-like receptor 6 (hTLR6, CD286). (invivogen.com)
  • Mouse anti Respiratory Syncytial Virus Nucleoprotein antibody, clone RSV3132 (B023) recognizes an epitope within the 42kD RSV nucleoprotein. (bio-rad-antibodies.com)
  • Mouse anti Respiratory Syncytial Virus Nucleoprotein antibody, clone RSV3132 (B023) can be used in immunofluorescence assays in conjunction with clone RSV3216 . (bio-rad-antibodies.com)
  • Mouse anti human CaMKK II antibody, clone AB01/3H6 recognizes calcium/calmodulin-dependant protein kinase kinase 2. (bio-rad-antibodies.com)
  • IHC staining of FFPE human small intestine with Aquaporin 4 antibody (clone AQP4/3324). (nsjbio.com)
  • SDS-PAGE analysis of purified, BSA-free Aquaporin 4 antibody (clone AQP4/3324) as confirmation of integrity and purity. (nsjbio.com)
  • Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Aquaporin 4 antibody (clone AQP4/3324). (nsjbio.com)
  • Mouse Fumonisin Monoclonal Antibody [Clone: 2A2] - 5x 0.1 mg (conc. (gentaur.fr)
  • Aggrecan monoclonal antibody to C-terminal neoepitope NITEGE (mouse, clone BC-13). (mdbioproducts.com)
  • Aggrecan monoclonal antibody to N-terminal neoepitope ARG (mouse, clone BC-3). (mdbioproducts.com)
  • Aggrecan IGD monoclonal antibody (mouse, clone 6B4). (mdbioproducts.com)
  • Cartilage-link protein (HAPLN1) monoclonal antibody (clone 8A4). (mdbioproducts.com)
  • Chondroitin sulfate monoclonal antibody (mouse, clone 1B5) to detect the zero sulphated Chondroitin Sulphate stub neoepitope generated by chondroit. (mdbioproducts.com)
  • Chondroitin-4-sulfate (C-4-S) monoclonal antibody that's also specific to dermatan-sulfate (DS) neoepitope (mouse, clone 2B6). (mdbioproducts.com)
  • This antibody has been tested by dot blot and/or solid-phase adsorbed to ensure minimal cross-reactivity with mouse IgM, IgG 2a , IgG 2b , IgG 3 , and IgA, pooled human sera, and purified human paraproteins. (licor.com)
  • Changes in mucosal bacteria, and a switch from internal to surface antigen/antibody reactivity of a predominantly IgG1 type, leads to greater opsonisation of the respiratory burst in PMN, providing a mechanism for maintaining the inflammatory state in UC. (bmj.com)
  • Description: 33 types of normal tissues based on the FDA recommendation for antibody cross-reactivity testing. (caspase-14.com)
  • Mepolizumab is a humanised monoclonal antibody (IgG1, kappa), which targets human interleukin-5 (IL-5) with high affinity and specificity. (fip.org)
  • Based on ELISA and flow cytometry, the antibody reacts with the heavy chain of mouse IgG 1 . (licor.com)
  • The antibody MFG-06 reacts with a 40-45 kDa glycoprotein in human milk fat globule membrane preparation. (exbio.cz)
  • Antibody 1.3.3.22 reacts with the 24 kd tetraspan CD81 molecule (1). (ancell.com)
  • 544-MBS850641 Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal C3 Suitable for: IHC-P, WB Reacts with: Mouse, Rat, Human Antibodies that detect. (bioscience-explained.org)
  • 26-5993-100 Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal mCherry Suitable for: IP, WB Reacts with: Species independent Antibodies that detect. (bioscience-explained.org)
  • Description: This recombinant Human IgG1 antibody reacts to the heavy chain of hIgG1. (caspase-14.com)
  • Description: This recombinant Mouse IgG1 antibody reacts to the Fc region of mouse IgG1. (caspase-14.com)
  • Specificity: This antibody reacts with Fusarium fumonisin mycotoxin. (gentaur.fr)
  • Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. (novusbio.com)
  • 24-SC-52425 Mouse monoclonal [10B7] to HSV1 + HSV2 gB Suitable for: WB, ELISA, ICC/IF Isotype: IgG1 General notes The Life Science industry has been in the grips of a reproducibility crisis for a number of years. (bioscience-explained.org)
  • 592-781553 Antibodies that detect p16INK4a can be used in several scientific applications, including Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunohistochemistry and ELISA. (bioscience-explained.org)
  • 247-OAEF00516 Mouse monoclonal Yellow Fever Virus NS1 Suitable for: ELISA Isotype: IgG1 Specificity This antibody is specific for the NS1 protein of Yellow Fever virus, and does not cross-react with NS1 from other. (bioscience-explained.org)
  • This IgG1 antibody is for WB, IHC-P, ELISA. (caspase-14.com)
  • If you buy Antibodies supplied by Chondrocytes and collagens they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. (assayspro.com)
  • Specificity validations include antibody recognition of recombinant p21 by western blot (Koike, 2011) and in direct ELISA assays (Rossner, 2002 & 2007). (scytek.com)
  • After generation of hybridomas, we identified clones producing antibody against WU-VP1 by ELISA and immunoblot. (cdc.gov)
  • An isotype control should be used at the same concentration as the antibody of interest (e.g., ≤ 1 µg/million cells for flow cytometry). (bdbiosciences.com)
  • Antibody 96.2C1 has been used for flow cytometry to analyze circulating Endothelial Microparticles (3). (ancell.com)
  • The antibody MEM-241 recognizes an extracellular epitope of CD4 antigen, a 55 kDa transmebrane glycoprotein expressed on a subset of T lymphocytes ("helper" T-cells) and also on monocytes, tissue macrophages and granulocytes. (exbio.cz)
  • Antibody 96.2C1 recognizes the CD41a of about 140 kd (1). (ancell.com)
  • 270-11-302-C100 Mouse monoclonal [1696] to HIV protease Suitable for: Dot blot Isotype: IgG1 Specificity The antibody recognizes free N-terminus of mature HIV protease (HIV-1 and HIV-2). (bioscience-explained.org)
  • Be the first to review Rat IgG1 Alexa Fluor® 594-conjugated Antibody and earn rewards! (rndsystems.com)
  • Have you used Rat IgG1 Alexa Fluor® 594-conjugated Antibody? (rndsystems.com)
  • The antibody detects endogenous Collagen II protein. (biocheminfo.org)
  • This antibody detects aggrecan metabolites (intact or matrix protease-catabolised) in human sy. (mdbioproducts.com)
  • Specificity Antibody is affinity-purified on mouse IgG2b. (qedbio.com)
  • Systemic antibody responses were measured against total antigens and surface antigens of these organisms in UC and Crohn's disease (CD) patients, together with healthy controls. (bmj.com)
  • UC patients had higher IgG responses to surface antigens, primarily IgG1, whereas the response in CD was mainly IgG2. (bmj.com)
  • Instead, the antibody retains affinity for the same antigens, but can interact with different effector molecules. (wikipedia.org)
  • Antibodies recognize specific configurations (epitopes, or antigenic determinants) on the surfaces of antigens (eg, proteins, polysaccharides, nucleic acids). (msdmanuals.com)
  • Antibodies and antigens fit tightly together because their shape and other surface properties (eg, charge) are complementary. (msdmanuals.com)
  • The same antibody molecule can cross-react with related antigens if their epitopes are similar enough to those of the original antigen. (msdmanuals.com)
  • The Fc portion of these biological agents binds specifically to cell surface Fcγ receptors (FcγR) and this may affect their half life and certain innate and adaptive immune responses, such as phagocytosis and antibody-dependent cellular cytotoxicity (ADCC). (bmj.com)
  • Our findings demonstrate that a single intramuscular injection in mice of AAV encoding R1a-B6 fused to Fc fragments of different isotypes equipped either, with or without antibody dependent cellular cytotoxicity (ADCC) activity, was able to drive sustained high-level expression (0.5-1.1 mg/mL) in sera with no evidence of reduction for up to 6 months. (frontiersin.org)
  • Mediates antibody-dependent cellular cytotoxicity (adcc) and other antibody-dependent responses, such as phagocytosis. (lu.se)
  • This product is an ADCC enhanced antibody produced by our Afuco™ platform. (creativebiolabs.net)
  • The anti-PD-L1 IgG1 isotype, which is capable of mediating ADCC, was also able to recruit human NK cells to the tumor site in vivo . (oncotarget.com)
  • Vaccine-induced antibodies were characterized by isotype, subclass, and epitope specificity, and tested for the ability to fix and activate complement. (biomedcentral.com)
  • We have previously described R1a-B6, an alpaca-derived single domain antibody (nanobody), that is capable of potent cross-subtype neutralization in vitro of H1N1, H5N1, H2N2, and H9N2 influenza viruses, through binding to a highly conserved epitope in the influenza hemagglutinin stem region. (frontiersin.org)
  • Although the exact epitope for the antibody has not been mapped, the epitope appears to be different from those recognize by other p21 antibody clones. (scytek.com)
  • The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. (bdbiosciences.com)
  • Eptinezumab is a monoclonal immunoglobulin G1 (IgG1) antibody that binds to human calcitonin gene-related peptide (CGRP) with high specificity and high affinity for the CGRP α- and β-form. (lundbeck.com)
  • IgG1, IgG2 etc. (wikipedia.org)
  • In humans, the order of the heavy chain exons is as follows: μ - IgM δ - IgD γ3 - IgG3 γ1 - IgG1 α1 - IgA1 γ2 - IgG2 γ4 - IgG4 ε - IgE α2 - IgA2 Class switching occurs by a mechanism called class switch recombination (CSR) binding. (wikipedia.org)
  • Statistical modeling suggested the decay in complement-fixing antibodies was mostly attributed to the waning of anti-CSP IgG1, and to a lesser extent IgG3. (biomedcentral.com)
  • Isoform VAL-157 shows a higher binding capacity of IgG1, IgG3 and IgG4 compared with isoform PHE-157. (lu.se)
  • ab313596 is a mouse monoclonal chimeric antibody. (abcam.com)
  • IRDye 680LT Goat anti-Mouse IgG1-Specific Secondary Antibody. (licor.com)
  • Isolation of specific antibodies was accomplished by affinity chromatography on mouse IgG 1 covalently linked to agarose. (licor.com)
  • We recommend FITC-conjugated mouse IgG1 κ mAb MOPC-21 (Cat. (bdbiosciences.com)
  • Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. (novusbio.com)
  • Western blot analysis of whole cell lysates (25 µg) probed with Mouse anti human CaMKK II primary antibody (MCA6427GA) at a 1/2000 dilution followed by detection with Goat anti mouse HRP conjugate ( 1705047 ) at a 1/20000 dilution and visualized on the ChemiDoc MP imaging system. (bio-rad-antibodies.com)
  • Recombinant Humanized (from mouse) antibody to Human MUC1. (siqik.com)
  • ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. (abcam.com)
  • Choose a good quality enzyme-linked anti-mouse IgG1 antibody for detection). (enzolifesciences.com)
  • Hapten-specific IgE antibodies were detected in the sera of English short-hair strain guinea pigs immunized with either toluene diisocyanate -human serum albumin (TDI-HSA) or hexamethylene diisocyanate -HSA (HDI-HSA) when these sera were analyzed by the 168 hr passive cutaneous anaphylaxis (PCA) technique followed by intravenous challenges with conjugates of respective ligands coupled to an unrelated carrier protein, transferrin. (cdc.gov)
  • It was therefore apparent that immune responses of guinea pigs immunized with protein conjugates of bifunctional isocyanate s were heterogeneous and involved multiple specificities for hapten, carrier protein, and new antigenic determinants. (cdc.gov)
  • Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. (nsjbio.com)
  • Description: The human tissue blot is designed for proteomics research in screening for antibody and protein expression. (caspase-14.com)
  • Immunohistochemistry-Paraffin: HMG2L1 Antibody (3C12) [H00010042-M03] - Analysis of monoclonal antibody to HMG2L1 on formalin-fixed paraffin-embedded human lung. (novusbio.com)
  • Western Blot: SOS1 Antibody (SOS-01) [NB110-68800] - Analysis (reducing conditions) of human Sos using anti-human Sos (SOS-1). (novusbio.com)
  • In most cases, this is achieved by the use of chimeric and humanised monoclonal IgG antibodies (ie, infliximab, rituximab and adalimumab) or fusion proteins consisting of the molecule of interest fused to the constant region (Fc) of human IgG (ie, etanercept and abatacept). (bmj.com)
  • It is a U.S. Food and Drug Administration (FDA) approved human monoclonal antibody, and works by activating the immune system by targeting CTLA-4. (creativebiolabs.net)
  • Human Antibody Laboratories manufactures the normal human igg1 antibody reagents distributed by Genprice. (caspase-14.com)
  • The Normal Human Igg1 Antibody reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (caspase-14.com)
  • Description: A polyclonal antibody for detection of IgG1 from Human. (caspase-14.com)
  • Description: A Rabbit Polyclonal antibody against IgG1 from Human. (caspase-14.com)
  • Description: A Rabbit polyclonal antibody against Human Normal Mucosa Of Esophagus Specific 1 (NMES1). (caspase-14.com)
  • Herein we used a single bicistronic lentiviral vector to develop a new combination immunotherapy that consists of human anti-carbonic anhydrase IX (CAIX)-targeted chimeric antigen receptor (CAR) T cells engineered to secrete human anti-programmed death ligand 1 (PD-L1) antibodies at the tumor site. (oncotarget.com)
  • These armed second-generation CAR T cells empowered to secrete human anti-PD-L1 antibodies in the ccRCC milieu to combat T cell exhaustion is an innovation in this field that should provide renewed potential for CAR T cell immunotherapy of solid tumors where limited efficacy is currently seen. (oncotarget.com)
  • Antibodies from UC patients greatly enhanced the respiratory burst in PMN, in response to individual bacterial species. (bmj.com)
  • The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. (bdbiosciences.com)
  • this antibody can be used for staining of paraffin-embedded tissue sections fixed in neutral buffered formalin and is compatible with most commonly used histological fixatives. (enzolifesciences.com)
  • IgG1 antibodies and precipitating antibodies were demonstrated in Hartley strain guinea pigs immunized with TDI/HDI-HSA conjugates. (cdc.gov)
  • Results with your primary antibody may vary and specificity should be confirmed prior to performing two-color detection. (licor.com)
  • Negative control inset: PBS instead of primary antibody to control for secondary binding. (nsjbio.com)
  • The prevalence of serum IgG antibodies to Type II Collagen in American patients with rheumatoid arthritis. (assayspro.com)
  • Terato K., DeArmey D.A., Ye X.J., Griffiths M.M., Cremer M.A. The Mechanism of Autoantibody Formation to Cartilage in Rheumatoid Arthritis: Possible Cross-Reaction of Antibodies to Dietary Collagens with Autologous Type II Collagen. (assayspro.com)
  • Specificity of antibodies to type II collagen in rheumatoid arthritis. (assayspro.com)
  • We also demonstrated that antibody-capture is effective for purification and concentration of BoNTs from complex matrices such as clinical samples. (cdc.gov)
  • Endopep-MS currently uses an antibody-affinity concentration/purification step before the enzymatic reaction with the substrate, and the choice of antibody is critical for the success of this assay [ 5 ]. (cdc.gov)
  • This allows different daughter cells from the same activated B cell to produce antibodies of different isotypes or subtypes (e.g. (wikipedia.org)
  • Class switching occurs after activation of a mature B cell via its membrane-bound antibody molecule (or B cell receptor) to generate the different classes of antibody, all with the same variable domains as the original antibody generated in the immature B cell during the process of V(D)J recombination, but possessing distinct constant domains in their heavy chains. (wikipedia.org)
  • Still another object of the present invention is to provide a nucleic acid molecule encoding the antibody or antigen-binding fragment thereof, a recombinant expression vector containing the nucleic acid molecule, and a cell transformed with the recombinant expression vector. (justia.com)
  • Immunocytochemistry/ Immunofluorescence: HMG2L1 Antibody (3C12) [H00010042-M03] - Analysis of monoclonal antibody to HMGXB4 on HeLa cell. (novusbio.com)
  • During CSR, portions of the antibody heavy chain locus are removed from the chromosome, and the gene segments surrounding the deleted portion are rejoined to retain a functional antibody gene that produces antibody of a different isotype. (wikipedia.org)
  • A more practical and cost-effective strategy would be to use antibody gene therapy which would provide long term sustainable protection through antibody production within the patient. (frontiersin.org)
  • During class switching, the constant region of the immunoglobulin heavy chain changes but the variable regions do not, and therefore antigenic specificity, remains the same. (wikipedia.org)
  • ABSTRACT A serological study was carried out in Tiaret province in western Algeria on 1032 cows distributed in 95 flocks to estimate the prevalence of Brucella infection and to compare the sensitivity and specificity of a range of agglutination tests. (who.int)
  • The complement fixation test evaluate a number of serological tests and was (CFT) used as the gold standard for to discuss some epidemiological aspects of measuring the sensitivity and specificity of brucellosis. (who.int)
  • Passive transfer of serum antibodies from convalescent patients has been used in the past ( 7 , 8 ), however, this approach is of limited use in a global pandemic emergency. (frontiersin.org)
  • Antibody Genetic recombination Immune checkpoint Immunogenetics Bauer G (2020). (wikipedia.org)
  • This implies that G1m1 B cells are selected to the central nervous system of multiple sclerosis patients regardless of specificity and suggests that an antigen‐independent mechanism could drive the intrathecal humoral immune response. (uib.no)
  • Recent studies identified antibody-complement interactions as a potentially important immune mechanism against sporozoites. (biomedcentral.com)
  • The local antibody delivery led to marked immune checkpoint blockade. (oncotarget.com)
  • The aim of this investigation was to compare the principal culturable bacterial populations on the rectal mucosa of UC patients, and to determine whether specific antibodies towards these bacteria can activate infiltrating PMN through opsonisation. (bmj.com)
  • If these activated B cells encounter specific signaling molecules via their CD40 and cytokine receptors (both modulated by T helper cells), they undergo antibody class switching to produce IgG, IgA or IgE antibodies. (wikipedia.org)
  • Conversely, intrathecally synthesized varicella zoster virus‐specific IgG1 in varicella zoster virus meningoencephalitis comprised both allotypes. (uib.no)
  • The present invention relates to an anti-tyrosinase antibody for inhibiting tyrosinase and use thereof, and more particularly, to an anti-tyrosinase antibody including a heavy chain CDR and a light chain CDR of specific sequences, or an antigen-binding fragment thereof. (justia.com)
  • One vial containing 420 mg of trastuzumab, a humanised IgG1 monoclonal antibody produced by mammalian (Chinese hamster ovary) cell suspension culture and purified by chromatography including specific viral inactivation and removal procedures. (who.int)