Hypertension, PulmonaryPulmonary ArteryBone Morphogenetic Protein Receptors, Type IIEpoprostenolMonocrotalineAntihypertensive AgentsIloprostPulmonary Veno-Occlusive DiseaseHypertrophy, Right VentricularSulfonesScleroderma, SystemicSulfonamidesVasodilator AgentsVentricular Dysfunction, RightPurinesHypertensionHemodynamicsPulmonary Wedge PressureExercise ToleranceCarbolinesLungMyocytes, Smooth MuscleCardiac CatheterizationVascular ResistanceLung TransplantationExercise TestPhosphodiesterase 5 InhibitorsTreatment OutcomeEisenmenger ComplexDrug Therapy, CombinationSeverity of Illness IndexRetrospective StudiesBlood PressureCase-Control StudiesReceptors, EndothelinConnective Tissue DiseasesPulmonary CirculationArterial PressureFollow-Up StudiesPiperazinesMuscle, Smooth, VascularProspective StudiesPhenylpropionatesHypertension, PortalSurvival RateHypertension, RenalIdiopathic Pulmonary FibrosisVentricular Function, RightAnoxiaProstaglandins IDexfenfluramineProstaglandins, SyntheticPhosphodiesterase InhibitorsCells, CulturedCyclic Nucleotide Phosphodiesterases, Type 5Receptor, Endothelin ADisease Models, AnimalPyridazinesHypertension, RenovascularTelangiectasia, Hereditary HemorrhagicHeart Defects, CongenitalRisk FactorsTime FactorsHeart-Lung TransplantationAdministration, InhalationNatriuretic Peptide, BrainReceptor, Endothelin BIsoxazolesSmad8 ProteinEchocardiographyWalking3',5'-Cyclic-GMP PhosphodiesterasesThiophenesEchocardiography, DopplerEndothelin-1Pregnancy Complications, CardiovascularPrognosisPulmonary EmbolismPoisonsRats, Sprague-DawleyAdministration, OralNitric OxideChronic DiseaseVasoconstrictionHypertension, MalignantHeart VentriclesCohort StudiesEndothelium, VascularPrevalenceCardiac OutputVentricular PressureEndothelial CellsBiological MarkersRespiratory Function TestsActivin Receptors, Type IISmad Proteins, Receptor-RegulatedDisease ProgressionDyspneaCell ProliferationTGF-beta Superfamily Proteins