• Antifreeze proteins provide fish with protection against the freezing effect of polar environments by binding to ice surfaces and inhibiting growth of ice crystals. (tue.nl)
  • Advances in the protein's production technologies make these proteins promising agents for medical applications among others.Here, we focus on a special class of IBPs that suppress freezing by causing thermal hysteresis (TH): Antifreeze proteins (AFPs). (huji.ac.il)
  • Like some other coldwater fish, it has antifreeze proteins, which allow it to survive at temperatures around or slightly below freezing. (wikipedia.org)
  • Antifreeze proteins from the shorthorn sculpin, Myoxocephalus scorpius: isolation and characterization. (wikipedia.org)
  • But the breakthrough came when I joined a crystallography lab and began to look at how antifreeze proteins can interact with ice crystals. (uoguelph.ca)
  • My longstanding interest in antifreeze proteins has continued as an independent investigator as a second focus. (uoguelph.ca)
  • And we now know they were the first animal to develop antifreeze proteins. (yubanet.com)
  • The springtail might have been the first animal to ever develop antifreeze proteins. (yubanet.com)
  • We knew that antifreeze proteins had developed independently of each other several times during evolutionary history. (yubanet.com)
  • Our work focuses primarily on antifreeze proteins. (dal.ca)
  • As a result of ice binding, antifreeze proteins can depress of the solution freezing point, modulate the ice nucleation temperature and alter of the tendency of ice to coalesce through recrystallization. (dal.ca)
  • Antifreeze proteins have been proposed to protect cells at cold temperatures above the freezing point, where no ice is present. (dal.ca)
  • Therefore, we are testing hypotheses regarding hypothermic protection by antifreeze proteins using informative cell models. (dal.ca)
  • Antifreeze proteins (AFPs) bind to ice crystals to prevent organisms from freezing. (bvsalud.org)
  • This property allows them to affect ice growth in multiple ways: Shaping ice crystals, suppressing the freezing point, inhibiting recrystallization and promoting nucleation. (huji.ac.il)
  • A protein in its blood and tissues binds to tiny ice crystals and stops them from growing. (nature.com)
  • These cryoprotectants lower the freezing point of water and allow cell contents to "supercool" without forming damaging ice crystals. (umd.edu)
  • This Rat X-box-binding protein 1 (XBP1) ELISA Kit employs a two-site sandwich ELISA to quantitate XBP1 in samples. (abbkine.com)
  • Rat X-box-binding protein 1 (XBP1) ELISA Kit has high sensitivity and excellent specificity for detection of Rat XBP1. (abbkine.com)
  • Abbkine ELISA kit is series of sandwich ELISA to quantitate specific protein in samples. (abbkine.com)
  • Investigating the dynamics of recombinant protein secretion from a microalgal host. (nih.gov)
  • Sample: Recombinant protein. (biomatik.com)
  • The 678 amino acid recombinant protein has a predicted molecular mass of approximately 76 kD. (biolegend.com)
  • Beetle hyperactive antifreeze protein (AFP) has a unique ability to maintain a supercooling state of its body fluids, however, less is known about its origination. (mdpi.com)
  • High water mobility on the ice-binding surface of a hyperactive antifreeze protein. (lu.se)
  • During my graduate studies, I studied diverse protein/ligand systems, including amyloid (Alzheimer) proteins interacting with basement membrane proteins, and the role of calmodulin and caldesmon in smooth muscle regulation. (uoguelph.ca)
  • NMR also lends itself to the detailed study of protein/ligand interactions, and is able to characterize proteins both in solution and in a solid such as ice or membranes. (uoguelph.ca)
  • Our group is interested in understanding how antifreeze protein binds to its ligand. (uoguelph.ca)
  • The kinetic of elevation of intracellular [Ca 2+ ] slowed with increasing fatty acid chain length, suggesting different ligand on-rates, whereas the addition of fatty acid-free bovine serum albumin reduced signals, presumably by binding the fatty acids. (aspetjournals.org)
  • To allow effective ligand equilibration, GPR40-Gα q was used in guanosine 5′- O -(3-[ 35 S]thio)triphosphate ([ 35 S]GTPγS) binding assays. (aspetjournals.org)
  • A dry ligand-binding cavity in a solvated protein. (lu.se)
  • The solute carrier (SLC) transporter superfamily comprises an ancient and ubiquitous group of proteins capable of translocating a range of nutrients, endogenous molecules, and xenobiotics. (bvsalud.org)
  • Ice-binding proteins (IBPs) are unique molecules that bind to and are active on the interface between two phases of water: Ice and liquid water. (huji.ac.il)
  • I began to appreciate that complex biological process can be understood in terms of the interaction of proteins and other biological molecules, an idea which still intrigues me to this day. (uoguelph.ca)
  • NMR is an extremely powerful technique for understanding protein structure and function, especially since it is able to characterize the flexibility of biological molecules. (uoguelph.ca)
  • These 'networks' were inferred to be dynamic and poorly-ordered, consisting of several DNA loops between distally bound ParB molecules. (elifesciences.org)
  • Nanosecond to microsecond protein dynamics probed by magnetic relaxation dispersion of buried water molecules. (lu.se)
  • IDPs are fascinating proteins since they often fail to follow biochemical dogma (lack of structure, high specificity in the absence of high affinity). (uoguelph.ca)
  • The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. (abcam.com)
  • Several methods were used to characterize these AFPs, including isolation by ice affinity purification, MALDI mass spectrometry, amino acid composition analysis, tandem mass spectrometry sequencing, transcriptome sequencing, and bioinformatic investigations of sequence databases. (bvsalud.org)
  • E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. (phosphatidylinositol.com)
  • These reactive intermediates and reactive oxygen species can irreversibly damage DNA, proteins and lipids via covalent binding and oxidation, potentially initiating teratogenesis and other toxicities. (aspetjournals.org)
  • Bioturbation Energy costs Hyposalinity Fluctuating salinity Mitochondria Aerobic capacity Energy reserves Proteins Lipids Glycogen Burrowing benthic organisms (bioturbators) serve as ecosystem engineers. (biologists.com)
  • Product Description: Alpilean uses six plant-based superfood nutrients sourced directly from the Alpine region with a secret ice hack method for faster weight loss results by normalizing and optimizing low core body temperature at the cellular level. (ndtv.com)
  • These proteins are expressed in plants during times of desiccative stress, and are thought to bind water, protect the cellular membrane from drying and prevent proteins from denaturing. (uoguelph.ca)
  • The main advantage of this technique is the high efficiency of co-expressing cellular fusion proteins in one expression vector. (jove.com)
  • The coronavirus spike (S) glycoprotein is a class I viral fusion protein on the outer envelope of the virion that plays a critical role in viral infection by recognizing host cell receptors and mediating fusion of the viral and cellular membranes. (biolegend.com)
  • The trimeric SARS coronavirus (SARS-CoV-2) S glycoprotein consisting of three S1-S2 heterodimers binds the cellular receptor angiotensin-converting enzyme 2 (ACE2) and mediates fusion of the viral and cellular membranes through a pre- to post-fusion conformation transition. (biolegend.com)
  • PCBP1 along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. (prospecbio.com)
  • Conclusions: These studies extend the evidence for EGFRs as important cellular targets for components of HDE and they reveal novel patterns of EGFR phosphorylation and binding changes that vary among airway epithelial cell types. (cdc.gov)
  • We have developed a novel method for co-expressing multiple chimeric fluorescent fusion proteins in plants to overcome the difficulties of conventional methods. (jove.com)
  • Purified GST fusion proteins of the N and C termini of Na v 1.3 pull down contactin from lysates of transfected HEK 293 cells. (jneurosci.org)
  • The current studies provide novel insights into the pharmacology of GPR40 and indicate that G protein-coupled receptors which respond to fatty acids, and potentially to other lipid ligands, can be occupied by endogenous agonists before assay and that this may mask the pharmacology of the receptor and may be mistaken for high levels of constitutive activity. (aspetjournals.org)
  • Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Glycosylphosphatidylinositol Anchored High Density Lipoprotein Binding Protein 1 (GPIHBP1) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. (phosphatidylinositol.com)
  • The samples were tested in a binding assay with recombinant human ACE2-Fc Chimera. (biolegend.com)
  • DNA binding of single stranded DNA by T4 Gene 32 Protein was measured using a gel shift assay with a single-stranded, fluorescently labeled oligonucleotide. (qiagen.com)
  • Can be used to study CBP kinetics and regulation, for screening for inhibitors or activators and for radiolabeling of proteins or peptides with, for example [ 3 H]-Acetyl CoA. (enzolifesciences.com)
  • Time scales of water dynamics at biological interfaces: peptides, proteins and cells. (lu.se)
  • The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. (embl-heidelberg.de)
  • A diversity of AFP folds has been found in fish and insects, including alpha helices, globular proteins, and several different beta solenoids. (bvsalud.org)
  • Freezing from the inside: Ice nucleation in Escherichia coli and Escherichia coli ghosts by inner membrane bound ice nucleation protein InaZ. (mpg.de)
  • ABSTRACT In order to define the protein expressional changes related to the process of meglumine antimoniate resistance in anthroponotic cutaneous leishmaniasis (CL), we performed a comparative proteomics analysis on sensitive and resistant strains of Leishmania tropica isolated from Iranian CL patients. (who.int)
  • TRAIL, also called Apo2L, is a cytotoxic protein that induces apoptosis of many transformed cell lines but not of normal tissues, even though its death domain-containing receptor, DR4, is expressed on both cell types. (embl-heidelberg.de)
  • XCL1 induces it chemotactic function by binding to a chemokine receptor called XCR1. (abbkine.com)
  • In addition to plexins, various other proteins have been implicated either as receptors for semaphorins or as components of the semaphorin receptor complex ( Pasterkamp and Kolodkin, 2003 ). (rupress.org)
  • The S1 subunit contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. (biolegend.com)
  • Biphasic changes in airway epithelial cell EGF receptor binding and phosphorylation induced by components of hogbarn dust. (cdc.gov)
  • Influenza virus neuraminidase (NA) can act as a receptor-binding protein, a role commonly attributed to hemagglutinin (HA). (cdc.gov)
  • Image analysis of the matched maps identified 7 proteins that were either over- or down-expressed: activated protein kinase c receptor (LACK), alpha tubulin (×2), prostaglandin f2-alpha synthase, protein disulfide isomerase, vesicular transport protein and a hypothetical protein. (who.int)
  • Members of this family show sequence homology with estrogen receptors but are incapable of being bound by estrogen. (nature.com)
  • The glucuronidation and elimination of endogenous compounds ( e.g. , bilirubin) and xenobiotics, including HPPH, the major, para -hydroxylated metabolite of the anticonvulsant drug phenytoin (diphenylhydantoin) ( Butler, 1957 ), are catalyzed by a superfamily of membrane-bound isozymes known collectively as UGTs ( Dutton, 1980 ). (aspetjournals.org)
  • We present the X-ray crystal structure at 1.5 Å resolution of a lone a-helical antifreeze protein from winter flounder, which provides a detailed look at its ice-binding features. (tue.nl)
  • Sicheri, F & Yang, DSC 1995, ' Ice-binding structure and mechanism of an antifreeze protein from winter flounder ', Nature , vol. 375, pp. 427-431. (tue.nl)
  • Conversion of a winter flounder antifreeze protein from an alpha helix to an amyloid conformation can be quickly triggered by freezing and thawing. (dal.ca)
  • Dubé, A., Leggiadro, C. and Ewart, K.V. , (2016) Rapid amyloid fibril formation by a winter flounder antifreeze protein requires specific interaction with ice. (dal.ca)
  • Cell proteins were analysed with 2-dimensional electrophoresis and differentially expressed proteins were identified by matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry. (who.int)
  • Our preliminary study using 2D isolates were recovered from liq- new cases throughout the world cu- gel electrophoresis in drug sensitive/ uid nitrogen, and sub-cultured in taneous leishmaniasis (CL) remains resistant strains of L. tropica showed RPMI1640 medium (Gibco/BRL) a serious public health problem in that some proteins were differentially supplemented with 10% fetal bovine numerous countries [1,2]. (who.int)
  • There are several interactions that MAD2 shares with others, specifically, binding with Cdc20, in a vital protein-to-protein interaction. (prospecbio.com)
  • We show here that while the central DNA binding domain is essential for anchoring at parS , this interaction is not required for DNA condensation. (elifesciences.org)
  • PCBP1 and PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promotes poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. (prospecbio.com)
  • TRID is a distinct gene product with an extracellular TRAIL-binding domain and a transmembrane domain but no intracellular signaling domain. (embl-heidelberg.de)
  • Plexins are widely expressed transmembrane proteins that mediate the effects of semaphorins. (rupress.org)
  • Their effects are mediated by plexins, a group of transmembrane proteins. (rupress.org)
  • More than 400 million years ago, an insect-like animal called the springtail developed a small protein that prevents its cells from freezing. (yubanet.com)
  • The animal's cells had begun to produce proteins that could protect the cell from freezing. (yubanet.com)
  • Therefore, in experiments using a recombinant antifreeze protein, we are investigating specific freezing events to further understand the processes involved. (dal.ca)
  • These Hexapods arose in the Ordovician Period with the two orders known to produce AFPs diverging around 400 million years ago during the Andean-Saharan Ice Age. (bvsalud.org)
  • Therefore, it is likely that the AFP arose then and persisted in many lineages through the following two ice ages and intervening warm periods, unlike the AFPs of fish which arose independently during the Cenozoic Ice Age beginning ~ 30 million years ago. (bvsalud.org)
  • In contrast, human disease-relevant amyloid-forming proteins tend to require long time intervals (hours to weeks) to form amyloid, which slows research. (dal.ca)
  • Therefore, we are evaluating the process of rapid amyloid formation by this antifreeze protein. (dal.ca)
  • PCBP1 is a single-stranded nucleic acid binding protein that binds preferentially to oligo dC. (prospecbio.com)
  • The native Gene 32 Protein from bacteriophage T4 (T4gp32) is a single-stranded DNA binding protein that is required for T4 DNA replication, recombination and repair. (qiagen.com)
  • The T4 Gene 32 Protein also stimulates the rate of synthesis of T4 DNA Polymerase on primed-single-stranded substrates showing a 5-10-fold increase in synthesis rate. (qiagen.com)
  • The T4 Gene 32 Protein is a single-stranded nucleic acid binding protein that has the function of stabilizing single-stranded regions of DNA. (qiagen.com)
  • Accumulation of sugars and protein complexes that bind water that serve as cryoprotectants. (umd.edu)
  • He discovered that dedicated machinery was required to terminate translation and recycle ribosomes from mRNA and contributed to studies of tRNA binding to translation complexes and the functional outcomes. (asbmb.org)
  • She discovered specific tRNA binding to mRNA-ribosome complexes, N-terminal protein modification by arginine and ribosome recycling in eukaryotes, the last step of protein synthesis. (asbmb.org)
  • These nucleoprotein complexes act as a positional marker of the origin and earmark this region for segregation in a manner somewhat analogous to eukaryotic centromeres and their binding partners. (elifesciences.org)
  • In particular, the relationship between these dynamic nucleoprotein complexes and the molecular architecture of the ParB protein is unclear and is the subject of the work presented here. (elifesciences.org)
  • In the early days of molecular biology, Akira Kaji studied protein synthesis and earned a Guggenheim fellowship to support this work. (asbmb.org)
  • The T4 Gene 32 Protein is intended for molecular biology applications. (qiagen.com)
  • The gene in question is fatty acid binding protein 7, or FABP7 for short. (thenakedscientists.com)
  • Generates three distance geometry structures for intestinal fatty acid binding protein from a set of NOE distance restraints and torsional restraints. (wustl.edu)
  • In cells lacking expression of Ca 2+ -mobilizing G proteins, coexpression of human GPR40 and Gα q allowed medium- and long-chain fatty acids to elevate intracellular [Ca 2+ ]. (aspetjournals.org)
  • After expression of GPR40-Gα q in HEK293 cells and membrane preparation basal binding of [ 35 S]GTPγSinGα q immunoprecipitates was high and not elevated substantially by fatty acids. (aspetjournals.org)
  • However, treatment of membranes with fatty acid-free bovine serum albumin reduced the basal [ 35 S]GTPγS binding in a concentration-dependent manner and allowed the responsiveness and pharmacology at GPR40 of each of the fatty acids thiazolidinediones and a novel small-molecule agonist to be uncovered. (aspetjournals.org)
  • We propose an ice-binding model that accounts for the binding specificity of the antifreeze protein along the axes of the {2021} ice planes. (tue.nl)
  • SARS-CoV-2 B.1.1.7 Spike Protein S1, amino acid Val16-Arg685 (Accession # QHD43416.1), with (HV69-70del, Y144del, N501Y, A570D, P681H) and a C-terminal 8-His tag was expressed in CHO cells. (biolegend.com)
  • These intriguing proteins are found in a number of cold-environment organisms such as fish, insects, plants and bacteria. (uoguelph.ca)
  • Chlorophyllide binding protein in Spodoptera littoralis: Functional Characterization and Analysis. (mpg.de)
  • What's good about oleosin is that it is a functional protein. (lu.se)
  • These consist of four repeated ice-binding motifs, the side chains of which are inherently rigid or restrained by pairwise side-chain interactions to form a flat binding surface. (tue.nl)
  • Antifreeze protein from shorthorn sculpin: identification of the ice-binding surface. (wikipedia.org)
  • Structure of an Intrinsically Disordered Stress Protein Alone and Bound to a Membrane Surface. (uoguelph.ca)
  • Detailed Analysis of the Ice Surface after Binding of an Insect Antifreeze Protein and Correlation with the Gibbs-Thomson Equation. (nih.gov)
  • Structural analysis of the C-terminal domain reveals a dimer with a lysine-rich surface that binds DNA non-specifically and is essential for DNA condensation in vitro. (elifesciences.org)
  • Materials and Methods: Cell surface EGFRs were quantified as binding to intact cells on ice. (cdc.gov)
  • Results: In BEAS-2B and primary human bronchial epithelial cells, HDE induced decreases in cell surface EGFR binding following both 15-min and 18-h exposures. (cdc.gov)
  • The T4 Gene 32 Protein has exhibited an ability to enhance the performance of several DNA synthesis-related activities in secondary-structure rich regions, including PCR amplification and DNA sequencing. (qiagen.com)
  • The ability of T4 Gene 32 Protein to enhance the performance of several DNA synthesis-related activities is based on its essential function in the replication of bacteriophage T4. (qiagen.com)
  • Instructions for using T4 Gene 32 Protein are provided in the corresponding kit protocol in the resources below. (qiagen.com)
  • Protein concentration (OD 280 ) of T4 Gene 32 Protein was determined by OD 280 absorbance. (qiagen.com)
  • Gp32 binds transiently and cooperatively to ssDNA template sequences as these entities are exposed by the processive helicase operating within the replication complex. (qiagen.com)
  • This binding puts these ssDNA sequences into optimal conformations for interacting with DNA polymerases and other replication proteins. (qiagen.com)
  • When recombinant SARS-CoV-2 B.1.1.7 Spike Protein S1 is immobilized at 2 μg/mL, recombinant human ACE2-Fc Chimera (Cat. (biolegend.com)
  • Recombinant SARS-CoV-2 B.1.1.7 Spike Protein S1 was aliquoted in PBS at 0.2 mg/mL. (biolegend.com)
  • VIR-7831 is an investigational dual-action SARS-CoV-2 mAb that binds to a conserved region of the spike protein. (scienceboard.net)
  • The denaturation of myofibrillar proteins play a dominant role in the quality changes of frozen stored fish muscle. (scialert.net)
  • reported that 8% trehalose exhibited the greatest protective effect against protein denaturation, as shown by the effectiveness in maintaining Ca 2+ -ATPase activity and protein solubility in tilapia ( Sarotherodon nilotica ) surimi during frozen storage. (scialert.net)
  • Protein cold denaturation as seen from the solvent. (lu.se)
  • The kinetic pinning model describes the dynamics of a growing ice face with proteins binding to it, which eventually slow it down to a halt. (huji.ac.il)
  • Performs 10 steps of molecular dynamics on a pre-equilibrated system of DHFR protein in a box or water using the AMOEBA force field. (wustl.edu)
  • Ice-nucleating bacteria control the order and dynamics of interfacial water. (mpg.de)
  • How proteins modify water dynamics. (lu.se)
  • Analysis of protein dynamics simulations by a stochastic point process approach. (lu.se)
  • Hydration dynamics of a halophilic protein in folded and unfolded states. (lu.se)
  • Slow internal protein dynamics from water 1 H magnetic relaxation dispersion. (lu.se)
  • Does the dynamic Stokes shift report on slow protein hydration dynamics? (lu.se)
  • Dynamics at the protein-water interface from 17 O spin relaxation in deeply supercooled solutions. (lu.se)
  • Stock solutions can also be prepared at 50 - 100 µg/mL in appropriate sterile buffer, carrier protein such as 0.2 - 1% BSA or HSA can be added when preparing the stock solution. (biolegend.com)
  • OBJECTIVE(S): To examine associations between Index of Concentration at the Extremes (ICE) measures for economic and racial segregation and HIV outcomes in the United States (U.S.) and Puerto Rico. (cdc.gov)
  • Changes in the mRNA abundance of key proteins involved in glycolysis, gluconeogenesis and glycogen breakdown were also monitored. (biologists.com)
  • Purity was assessed by comparing the aggregate mass of contaminant bands in the concentrated sample to the mass of the protein of interest band in the diluted sample. (qiagen.com)
  • Though the formation of clathrates around hydrophobic groups is the main phenomenon that drives binding, it is still unclear what features allow these clathrates to form on antifreeze protein surfaces but not on other proteins. (uoguelph.ca)
  • Direct Evidence for Aligned Binding of Cellulase Enzymes to Cellulose Surfaces. (mpg.de)
  • Although originally termed histone acetyltransferases (HATs) for their lysine acetylation activity on histone N-terminal tails, CBP and its paralogue, p300, have been shown to acetylate a variety of non-histone proteins including p53, DNA polymerase β and nuclear import factors. (enzolifesciences.com)
  • My interest in protein structures expanded as a post-doctoral fellow, where I learned how to use NMR (nuclear magnetic resonance) to study proteins. (uoguelph.ca)
  • The most widely used cryoprotectants for surimi are 4% sucrose, 4% sorbitol and 0.2-0.3% polyphosphates and they confer stability to surimi proteins during frozen storage ( Sultanbawa and Li-Chan, 2001 ). (scialert.net)
  • Moreover, the free C-terminal domain can rapidly decondense ParB networks independently of its ability to bind DNA. (elifesciences.org)
  • The ParB protein forms DNA bridging interactions around parS to condense DNA and earmark the bacterial chromosome for segregation. (elifesciences.org)
  • Standards and samples are pipetted into the wells and anyXBP1 present is bound by the immobilized antibody. (abbkine.com)
  • The recommendation was based on an interim analysis of data from a phase III clinical study of 583 patients enrolled in the COVID-19 Monoclonal antibody Efficacy Trial -- Intent to Care Early (COMET-ICE) trial, which demonstrated an 85% reduction in hospitalization or death in patients receiving VIR-7831 compared to placebo. (scienceboard.net)
  • In 1960, Dr John A. Simpson introduced his hypothesis that the cause of MG was "an 'autoimmune' response of muscle in which an antibody to end-plate protein may be formed. (medscape.com)
  • NA-binding was observed when a virus preparation contained approximately 10% of NA variants with either T148I or T439R, highlighting the benefit of using deep sequencing in virus characterization. (cdc.gov)
  • These vectors are designed for protein transient expression and genetic transformation. (jove.com)
  • Transient access to the protein interior: Simulation versus NMR. (lu.se)
  • MAD2, standing for mitotic arrest deficient 2, is a spindle checkpoint protein that plays an integral role in the human body. (prospecbio.com)
  • This was also observed when human embryonic kidney (HEK) 293 cells were transfected with a GPR40-Gα q fusion protein. (aspetjournals.org)
  • In the depths of winter, water temperatures in the ice-covered Arctic Ocean can sink below zero. (nature.com)
  • Remove the sausage from the smoker and immediately shock them in a tub of ice water to stop them from cooking further and prevent shrinkage. (fieldandstream.com)
  • Performs a short MD simulation of the monoclinic ice V crystal form using the iAMOEBA water model, pairwise neighbor lists and PME electrostatics. (wustl.edu)
  • The analysis of these effects included the studying the changes in gel strength, gel whiteness, juiciness, folding, water-holding capacity, protein solubility and the pH level of the surimi. (scialert.net)
  • The addition of 6% polydextrose can maintain the gel strength, water-holding capacity and protein solubility at 82, 97 and 78%, respectively, lose 28% of moisture in juiciness and produce an average gel whiteness of 78.15. (scialert.net)
  • Surimi can be defined as a stabilized myofibrillar protein obtained from mechanically deboned fish flesh which is leached with cold water and mixed with cryoprotectants ( Park and Lin, 2005 ). (scialert.net)
  • Compressibility of the protein-water interface. (lu.se)
  • This means that the protein has the ability to place itself in the interface between water, air or fat, which means that it can be used as an emulsifier, like the yolk that binds oil with water when you make mayonnaise. (lu.se)
  • In Coca Cola, for example, the taste is bound to tiny fat droplets that float in the water", says Karolina Östbring. (lu.se)
  • This method can help answer key questions in the plant molecular and cell biology field such as, how can we proteins in the cell. (jove.com)
  • DEATH domain, found in proteins involved in cell death (apoptosis). (embl-heidelberg.de)
  • Other DD-containing proteins, such as ankyrin, MyD88 and pelle, are probably not directly involved in cell death signalling. (embl-heidelberg.de)
  • HDE stimulated EGFR phosphorylation at both 15 min and 18 hr in BEAS-2B cells and primary cells, but only at 15 min in H292 cells, indicating that the different EGFR binding changes among these cell types is likely related to their different time-dependent changes in phosphorylation. (cdc.gov)
  • When a microRNA is present in the cell, it binds to the target sites and downregulates GFP expression, while in cells that do not express the microRNA GFP, it is expressed. (lu.se)
  • protein patterns of subjects with leish- Cell culture maniasis [17]. (who.int)
  • There is no better time than starting 2023 on the right foot and this Alpileanreview will examine everything to know about the alpine ice hack pills to see if they are indeed proven weight loss ingredients or full of ungrounded and unfounded fake health claims like so many other fat burners on the market. (ndtv.com)
  • Some deli meat uses casein, a milk protein, to bind it together. (kidshealth.org)
  • Today we use either synthetic (chemically produced) or natural solutions from milk, egg or soy protein. (lu.se)
  • The underlying reason for trying to produce more proteins from plants is that it takes much more energy to cultivate traditional proteins from animals, milk and meat. (lu.se)
  • After publication of our story, we learnt that another scientist had suggested the de novo origin of antifreeze protein genes before Helle Baalsrud's team. (nature.com)
  • separate studies have revealed divergence between the 2 regions at unlinked genes encoding the normocyte binding protein ( 10 - 12 ) and the Duffy binding protein ( 13 , 14 ), as well as the 18S rRNA and mitochondrial cytochrome oxidase subunit 1 ( 15 ). (cdc.gov)
  • For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). (prospecbio.com)
  • Disorder and function: a review of the dehydrin protein family. (uoguelph.ca)
  • Working together, Akira and Hideko Kaji discovered that transfer RNA binds to ribosomes in the presence of messenger RNA to help facilitate translation - a key to Marshall Nirenberg winning a Nobel Prize in 1968 for "the genetic code and its function in protein synthesis. (asbmb.org)
  • Taken together, our findings provide new insights into the molecular mechanisms underlying the ability of NA to function as a binding protein. (cdc.gov)
  • They presented the quark at a competition about developing protein-rich foods from Scandinavian produce, organised by VINNOVA in November 2016. (lu.se)
  • Exercise promotes the formation of intracellular junctions in skeletal muscle between stacks of sarcoplasmic reticulum (SR) cisternae and extensions of transverse-tubules (TT) that increase co-localization of proteins required for store-operated Ca 2+ entry (SOCE). (elifesciences.org)