• Slipped capital femoral epiphysis (SCFE) is one of the most important pediatric and adolescent hip disorders encountered in medical practice. (medscape.com)
  • [ 6 , 7 ] Despite the fact that the underlying defect may be multifactorial (eg, mechanical and constitutional factors), SCFE represents a unique type of instability of the proximal femoral growth plate. (medscape.com)
  • The risk of SCFE is increased in children who are obese, as well as in children with other medical issues such as hypothyroidism, low growth hormone level, pituitary tumors, craniopharyngioma, Down syndrome , renal osteodystrophy , and adiposogenital syndrome. (medscape.com)
  • Slipped capital femoral epiphysis (SCFE or skiffy, slipped upper femoral epiphysis, SUFE or souffy, coxa vara adolescentium) is a medical term referring to a fracture through the growth plate (physis), which results in slippage of the overlying end of the femur (metaphysis). (wikipedia.org)
  • citation needed] Failure to treat a SCFE may lead to: death of bone tissue in the femoral head (avascular necrosis), degenerative hip disease (hip osteoarthritis), gait abnormalities and chronic pain. (wikipedia.org)
  • In general, SCFE is caused by increased force applied across the epiphysis, or a decrease in the resistance within the physis to shearing. (wikipedia.org)
  • Skeletal changes may also make someone at risk of SCFE, including femoral or acetabular retroversion, those these may simply be chronic skeletal manifestations of childhood obesity. (wikipedia.org)
  • SCFE is a Salter-Harris type 1 fracture (fracture through the physis or growth plate) through the proximal femoral physis, which can be distinguished from other Salter-Harris type 1 fractures by identifying prior epiphysiolysis, an intact (in chronic SCFE) or partially torn (in acute SCFE) periosteum, and the displacement being slower. (wikipedia.org)
  • Although it is not the epiphysis that displaced, by convention, position and alignment in SCFE is described by referring to the relationship of the proximal fragment (capital femoral epiphysis) to the normal distal fragment (femoral neck). (wikipedia.org)
  • Slipped capital femoral epiphysis (SCFE) is displacement of the femoral head (epiphysis) relative to the femoral neck (metaphysis). (unboundmedicine.com)
  • Slipped Capital Femoral Epiphysis SCFE is seen most often in obese adolescent African American boys during their rapid growth spurt (10-16 years of age). (orthofixar.com)
  • Ultrasonography and MRI have been used for diagnosis and evaluation of Slipped Capital Femoral Epiphysis SCFE. (orthofixar.com)
  • Slipped capital femoral epiphysis (SCFE) is a disorder of the adolescent hip in which the upper part of the femur (head) slips through the growth plate (physis) and results in displacement of the overlying head on the neck of the femur. (luriechildrens.org)
  • In SCFE, the top of the ball slips off the rest of the femur through the growth plate. (luriechildrens.org)
  • Endocrine diseases that increase the risk of SCFE include hypothyroidism , hypopituitarism and renal osteodystrophy. (luriechildrens.org)
  • Failure to treat a SCFE may result in complete separation of the femoral head on the neck. (luriechildrens.org)
  • Bones: Structure and Types (SCFE) is an orthopedic disorder of early adolescence characterized by the pathologic "slipping" or displacement Displacement The process by which an emotional or behavioral response that is appropriate for one situation appears in another situation for which it is inappropriate. (lecturio.com)
  • Anaphylaxis occurred in only one patient, and unilateral slipped capital femoral epiphysis (SCFE) in another one patient. (e-apem.org)
  • Recently, there have been reports indicating that administration of GnRHa may be a risk factor for the development of slipped capital femoral epiphysis (SCFE) 7 , 8 , 9 , 10) . (e-apem.org)
  • Slipped Capital Femoral Epiphysis is a disorder of proximal femoral epiphysis where there is a slippage of the epiphysis relative to the femoral neck. (orthofixar.com)
  • Radiography revealed epiphysiodesis in coxa vara with resorption of the femoral neck and evidence of avascular necrosis of the capital femoral epiphysis ( Fig. 1 ). (canjsurg.ca)
  • It suggests a biomechanical issue such as ass avascular necrosis or a slipped capital femoral epiphysis. (dontforgetthebubbles.com)
  • Endocrine diseases may also contribute (though are far less of a risk than obesity), such as hypothyroidism, hypopituitarism, and renal osteodystrophy. (wikipedia.org)
  • Patients should be observed for evidence of glucose intolerance, hypopituitarism, malignant transformation of skin lesions, hypothyroidism, slipped capital femoral epiphysis, and intracranial hypertension. (salesandmarketingnetwork.com)
  • On plain radiographs, the femoral head is seen displaced, posteriorly and inferiorly in relation to the femoral neck and within the confines of the acetabulum. (medscape.com)
  • The term slipped capital femoral epiphysis is actually a misnomer, because the epiphysis (end part of a bone) remains in its normal anatomical position in the acetabulum (hip socket) due to the ligamentum teres femoris. (wikipedia.org)
  • Stress around the hip causes a shear force to be applied at the growth plate, with metaphysis anteriorly translating and externally rotating, while epiphysis remains within acetabulum. (wikipedia.org)
  • The femoral head maintains its position within the acetabulum, whereas the femoral neck displaces anteriorly and more commonly superolaterally (varus). (unboundmedicine.com)
  • The femoral epiphysis remains in the acetabulum, and the neck is displaced anteriorly and rotates externally. (orthofixar.com)
  • The femoral head remains in the acetabulum (hip socket) and the metaphysis ( neck of the femur) move in an anterior direction with external rotation. (luriechildrens.org)
  • A Klein line is a line drawn along the superior border of the femoral neck that would normally pass through a portion of the femoral head. (medscape.com)
  • Normally, the head of the femur, called the capital, should sit squarely on the femoral neck. (wikipedia.org)
  • It is actually the metaphysis (neck part of a bone) which slips in an anterior direction with external rotation. (wikipedia.org)
  • Stress across the proximal femoral physis results in slippage of the femoral neck relative to the head. (unboundmedicine.com)
  • The Klein line is a line along the anterior or superior aspect of the femoral neck that normally is intersected by the epiphysis. (orthofixar.com)
  • The head of the femur (capital femoral epiphysis) should sit squarely on the femoral neck and forms most of the "ball" on the ball-and-socket hip joint. (luriechildrens.org)
  • Repetitive microtrauma can produce stress fractures of the femoral neck, femoral shaft, tibial shaft and anterior tibial muscles (shin splints), tibial tubercle (Osgood-Schlatter disease), calcaneal insertion of the Achilles tendon (Sever disease) and metatarsals. (ubc.ca)
  • The capital femoral epiphysis appeared completely separated, and the femoral neck revealed cloacae. (canjsurg.ca)
  • The intraoperative finding of cloacae in the femoral neck and the presence of infected granulation tissue are definitive evidence of osteomyelitis. (canjsurg.ca)
  • If your child has hypothyroidism , short stature or other endocrine disorder, we can help with a referral to the appropriate specialist in Endocrinology and Diabetes . (childrensnational.org)
  • The cause of slipped capital femoral epiphysis is mostly unknown (idiopathic), although it may be associated with endocrine disorders (e.g., hypothyroidism or administration of growth hormone), renal osteodystrophy, malnutrition and radiation therapy. (canjsurg.ca)
  • A cross-table, or true, lateral view can help determine the extent of posterior displacement of the epiphysis, and a "frog-leg" lateral view best shows subtle slipping. (orthofixar.com)
  • Non-Hodgkin Lymphomas depends on the severity of the slip or displacement Displacement The process by which an emotional or behavioral response that is appropriate for one situation appears in another situation for which it is inappropriate. (lecturio.com)
  • Levothyroxine, at doses individualized according to patient response, is effective as replacement or supplemental therapy in hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis. (nih.gov)
  • Stress on the hip causes the epiphysis to move posteriorly and medially, relative to the metaphysis. (wikipedia.org)
  • A double density that is seen at the metaphysis when a femoral head is even mildly slipped posteriorly on the AP radiograph as compared with the contralateral hip. (orthofixar.com)
  • It occurs when the femur slips at the growth plate (physis) and doesn't fit in the hip socket correctly. (healthlinkbc.ca)
  • Somatropin should not be used for growth promotion in pediatric patients with closed epiphysis. (nutropin.com)
  • We are excited to bring this next-generation treatment to patients in the U. Food and Drug Administration (FDA) has approved NGENLA (somatrogon-ghla), a once-weekly, human growth hormone deficiency, central (secondary) hypothyroidism may first become evident or worsen during somatropin therapy should be carefully evaluated. (tonysarcone.com)
  • TEV-TROPIN(R) should not be used in patients with evidence of an active malignancy, progressive or recurrent underlying intracranial tumor, active proliferative or severe nonproliferative diabetic retinopathy, or closed epiphysis. (salesandmarketingnetwork.com)
  • Determine if epiphyses are closed and if intracranial lesions and tumor activity are present. (medicscientist.com)
  • Overtreatment may result in craniosynostosis in infants and premature closure of the epiphyses in pediatric patients with resultant compromised adult height. (drugcentral.org)
  • Hypothyroidism: As replacement in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidism. (pfizermedicalinformation.com)
  • The dose of THYRO-TABS for hypothyroidism or pituitary TSH suppression depends on a variety of factors including: the patient's age, body weight, cardiovascular status, concomitant medical conditions (including pregnancy), concomitant medications, co-administered food and the specific nature of the condition being treated. (pillintrip.com)
  • Patients with chronic slips may have mild or moderate shortening of the affected extremity, the leg may be in fixed external rotation, and a Trendelenburg gait may be present if the slip is of a moderate degree. (orthofixar.com)
  • The procedure involves the placement of one or two screws ("pins") into the femoral head to prevent further slippage. (luriechildrens.org)
  • When bilateral slips occur, the second slip usually occurs within 12 to 18 months of the initial slip. (orthofixar.com)
  • Slipped capital femoral epiphyses may occur more frequently in patients who develop these illnesses has not been established. (tonysarcone.com)
  • Other congenital anomalies (e.g., heart and gastrointestinal defects) and acquired conditions (e.g., hypothyroidism, hearing impairment, and celiac disease) occur more frequently in children with Down syndrome. (medicalhomeportal.org)
  • It is felt that an additional 20-40% will subsequently progress to bilateral slips. (medscape.com)
  • Radiograph of the hips 1 year after open reduction for slipped capital femoral epiphysis in the left hip. (canjsurg.ca)
  • Complete slipping of the capital femoral epiphysis secondary to hematogenous osteomyelitis is hitherto unreported in adolescent children. (canjsurg.ca)
  • A similar case of incomplete slipping of the capital femoral epiphysis secondary to septic arthritis of the hip in an adolescent has been reported. (canjsurg.ca)
  • In this case, the diagnosis of the slip was missed initially while the patient was being treated for chest infection. (canjsurg.ca)
  • This is an all too common error in slipping of the capital femoral epiphysis, and may delay the diagnosis for months or years. (canjsurg.ca)
  • [ 13 ] A study by Loder et al reported new seasonal variation findings in 10,350 cases of slipped capital femoral epiphysis. (medscape.com)
  • Cartilaginous erosion and a transverse cleft on the anterior surface of the femoral head. (orthofixar.com)
  • It's Developed by Loder, and it is prognostic for the severe complication of osteonecrosis of the femoral head . (orthofixar.com)
  • Slipped capital femoral epiphysis Epiphysis The head of a long bone that is separated from the shaft by the epiphyseal plate until bone growth stops. (lecturio.com)
  • Treatment should not be used in children with a growth velocity of less than 1 cm per year and near closure of epiphyses. (medicines.org.uk)
  • Radiography revealed a complete separation of the capital femoral epiphysis. (canjsurg.ca)
  • Our case differs because in our patient there was no history of trauma, complete separation of the epiphysis, delayed treatment, open reduction and a satisfactory functional outcome. (canjsurg.ca)
  • Abnormal movement along the growth plate results in the slip. (wikipedia.org)