• Our results reveal that similarities between the cuticular biochemical signatures of major plant groups (extant and fossil) are mostly consistent with recent phylogenetic hypotheses based on molecular and morphological data. (nature.com)
  • Subfamilial reconstruction is concordant with recent phylogenetic hypotheses, but with much higher support values. (biomedcentral.com)
  • This study presents one of the most robust phylogenetic hypotheses for the tribe Cercopithecini and demonstrates the advantages of SINE insertions for phylogenetic studies. (biomedcentral.com)
  • In fact, it was not until the mid-twentieth century that theoretical as well as methodological advances in the field of systematics led biologists to better supported phylogenetic hypotheses. (what-when-how.com)
  • The lack of internal-node resolution in the inferred phylogenetic hypotheses of these genera does not allow us to propose a clear scenario regarding the evolution of these traits. (noaa.gov)
  • Results: Ancestral-area reconstructions provided similar results for alternative phylogenetic hypotheses, placing the origin of Hormogastridae between southern France and the north-eastern Iberian Peninsula, and highlighting north-central Sardinia as a key ancestral area for diversification of eastern Hormogastridae (Hormogaster redii and H. samnitica). (ucm.es)
  • This essay will outline the contributions made by DNA sequencing data to plant phylogeny and its limitations. (nmmra.org)
  • DNA sequencing provided a high resolution, reliable method for the construction of phylogeny. (nmmra.org)
  • First of all, the authors constructed a time calibrated phylogeny of all ray-finned fishes, including 31,526 tips, 11,638 with genetic data. (molecularecologist.com)
  • In Chapter 2, I present a revision of the molecular phylogeny of the genus Draco by incorporating sequence data from nuclear markers. (escholarship.org)
  • Mitochondrial and nuclear markers were amplified and sequenced, and the hormogastrid phylogeny (using Bayesian and likelihood methods) and networks were investigated. (ucm.es)
  • Clostridium difficile infection: Evolution, phylogeny and molecular epidemiology. (cdc.gov)
  • Using nearly full-genome HIV sequence data improves phylogeny reconstruction in a simulated epidemic. (cdc.gov)
  • these link to more than 6 million nucleotide sequences. (datadryad.org)
  • Reconciled names linked to more than 600,000 nucleotide sequences, ~9% of all avian sequences on GenBank. (datadryad.org)
  • Nearly 10% of eBird/Clements names had nucleotide sequences listed under 2 or more GenBank names. (datadryad.org)
  • We describe the isolation and nucleotide sequence determination of 18S ribosomal DNA from one species of chaetognath and one acanthocephalan. (ox.ac.uk)
  • My central hypothesis is that accounting for multi-nucleotide mutational events alters the estimation of evolutionary rate parameters and represents an alternative path a gene may embark upon during their evolutionary history. (temple.edu)
  • We conducted maximum likelihood (ML), maximum parsimony (MP) and Bayesian (B) analyses on partial RNA polymerase largest (RPB1) and second largest subunit (RPB2) nucleotide sequences of 93 fusaria to infer the first comprehensive and well-supported phylogenetic hypothesis of evolutionary relationships within the genus and 20 of its near relatives. (usda.gov)
  • We employed nucleotide sequences of mitochondrial (ND6, ND6-ND3 intergenic spacer, ND3, ND2, COI, msh1 and 16S) and nuclear (28S and ITS2) genomic regions from several taxa to infer molecular phylogenetics and to examine the correspondence of morphological features with the underlying genetic information. (noaa.gov)
  • Phylogenetic comparison of these mammals by either anatomy or mitochondrial DNA has resulted in two conflicting hypotheses, Theria and Marsupionta, and has fueled a "genes versus morphology" controversy. (nih.gov)
  • We analyzed morphological and mitochondrial DNA sequence data from the Pulau Tioman specimen and found distinct differences to L. philippina and all other congeners. (bvsalud.org)
  • Anchored hybrid enrichment is a form of next-generation sequencing that uses oligonucleotide probes to target conserved regions of the genome flanked by less conserved regions in order to acquire data useful for phylogenetic inference from a broad range of taxa. (biomedcentral.com)
  • Phylogenomic analyses have been made possible by the dramatically decreasing costs of genome/transcriptome sequencing of non-model organisms [ 8 ]. (biomedcentral.com)
  • In order to generate these comprehensive phylogenomic data sets, several cost-effective alternatives to whole genome or transcriptome sequencing have been proposed. (biomedcentral.com)
  • Did you know that you can see epigenomic or other experimental data in NCBI's Genome Data Viewer (GDV)? (nih.gov)
  • Genome browser view at the human JUN gene showing NCBI gene annotation, Ensembl gene annotation, Cited Variations from dbSNP, as well as two H3K4me3 experimental data tracks from the GEO database (the first two arrows, in red) and an RNA-seq study from the SRA database (the last arrow, in blue). (nih.gov)
  • This hypothesis is fundamentally based on a synthesis of my own work, and others within the field, on the relationship of the evolutionary properties of functional coding regions of the genome. (temple.edu)
  • Arabidopsis was the first plant genome to be sequenced (1). (biologists.com)
  • Since then, over twenty years of research have continually improved the sequence and functional annotation of a genome that serves as a reference for an ever-increasing number of newly sequenced plant genomes (2). (biologists.com)
  • Researchers can find information for single genes or they can download data (sequences, descriptions, GO annotations) for sets of genes or even the whole genome. (biologists.com)
  • TAIR provides data search and browsing services, data analysis tools, and data visualization tools, such as genome browsers (e.g. (biologists.com)
  • Without the day and night effort of the CTL to identify samples that were rtPCR positive for SARS-CoV-2, catalog them, and share them with my group, we would not have had the opportunity to sequence the viral genome from those samples and compare them to assess transmission on a molecular level. (bu.edu)
  • Firstly, using a recently developed analytic design for combined pedigree and genome-wide molecular genetic data, we test whether rare genetic variants, CNVs, and structural variants make an additional contribution to the genetic variance in intelligence, neuroticism, and extraversion. (nature.com)
  • Despite the intrinsic complexity of human genome sequences, reads were easily mapped and analyzed, and all algorithms used provided the same results. (molvis.org)
  • Deeply conserved chordate noncoding sequences preserve genome synteny but do not drive gene duplicate retention. (mpg.de)
  • Timing and mechanism of ancient vertebrate genome duplications - the adventure of a hypothesis. (mpg.de)
  • Error rates, PCR recombination, and sampling depth in HIV-1 Whole Genome Deep Sequencing. (cdc.gov)
  • Construction of a Pan-Genome Allele Database of Salmonella enterica Serovar Enteritidis for Molecular Subtyping and Disease Cluster Identification. (cdc.gov)
  • Whole Genome Sequence and Comparative Genomics of the Novel Lyme Borreliosis Causing Pathogen, Borrelia mayonii. (cdc.gov)
  • With rapidly evolving clinical applications in sequencing of the human genome as well as the genomes of tumors, the traditional anatomic descriptions of cancer types will be supplemented by molecular classification based on tumor genetic aberrations. (cdc.gov)
  • This study examined the added value of whole genome sequencing (WGS) for investigating a non-point source outbreak of Salmonella ser. (who.int)
  • 2 Whole genome England and Central Coast local health districts of sequencing (WGS) is a high-resolution typing method NSW. (who.int)
  • Public Health labs can identify an increase in clinical specimens of the same molecular pattern by using techniques such as pulse-field gel electrophoresis (PFGE) pattern or whole genome sequence (WGS) and indicate that they might have a common exposure source. (cdc.gov)
  • Due to their incredibly diverse nature, importance as pollinators, and historical instability with regard to subfamilial and tribal classification, Syrphidae (flower flies or hoverflies) are an ideal candidate for anchored hybrid enrichment-based phylogenetics, especially since recent molecular phylogenies of the syrphids using only a few markers have resulted in highly unresolved topologies. (biomedcentral.com)
  • Molecular Phylogenetics and Evolution 39: 16-32. (wikipedia.org)
  • Molecular data have been an integral tool in the resolution of the evolutionary relationships and systematics of freshwater mussels, despite the limited number of nuclear markers available for Sanger sequencing. (mdpi.com)
  • The rise of molecular systematics over the past 30 years has resulted in a wealth of DNA sequences from around the globe. (datadryad.org)
  • Yet, advances in molecular systematics also have created taxonomic instability, as new estimates of evolutionary relationships and interpretations of species limits have required widespread scientific name changes. (datadryad.org)
  • Thanks in part to modern molecular techniques, the field of biological systematics has made great advances in assembling the Tree of Life. (biomedcentral.com)
  • Taxonomic instability, colloquially "splits, lumps, and shuffles," presents logistical challenges to large-scale biodiversity research because (1) the same species or sets of populations may be listed under different names in different data sources, or (2) the same name may apply to different sets of populations representing different taxonomic concepts. (datadryad.org)
  • For the phylogenetic relationships among the arboreal members of Cercopithecus , several types of molecular data, including X and Y chromosome DNA sequences, protein sequences and karyotypes, recognize a clade containing a cephus species group and a mitis group. (biomedcentral.com)
  • We will generate morphological, molecular (DNA sequences), and biological characters that will be used to test species concepts and hypotheses of relationship among agriculturally important moths. (usda.gov)
  • He then performs phylogenetic analysis using this data to test hypotheses about the evolution of species. (si.edu)
  • They distilled geographic distribution information for all marine fish species with data available, using AquaMaps, but incorporated expert opinions and museum records to refine distributions to estimate geographic ranges to 150 x 150 km grid cell resolution for 12,050 marine species. (molecularecologist.com)
  • Recent molecular studies indicate the existence of more species than previously considered valid, thus stressing the need for wider taxon sampling from natural host populations. (biomedcentral.com)
  • This is especially true for Europe where morphological evidence indicates higher species diversity than previously thought, but where molecular data are virtually lacking. (biomedcentral.com)
  • Our study provides a comprehensive reference library for precisely identified isolates of the European species and highlights the importance of an integrative approach for species identification linking molecular, morphological and biological data. (biomedcentral.com)
  • Because Fusarium species differ significantly in their ability to produce toxins and cause diseases of plants and animals, including humans, it is critical that robust and comprehensive web-accessible molecular data bases be developed to facilitate the rapid detection and accurate identification these fungi in our food supply. (usda.gov)
  • These data will facilitate identification and differentiation of Fusarium, and also enable prediction of the toxigenic or pathogenic potential of poorly studied species within this group. (usda.gov)
  • This new species resembles S. dennisgordoni with branching in one plane but has fairly different radiate sclerites and significantly divergent DNA sequences. (noaa.gov)
  • We determine population structure (with Bayesian clustering and principal component analysis), interspecific gene flow (by determining the distribution of species-diagnostic alleles) and phylogenetic relationships (by maximum likelihood inference of concatenated sequence data and based on a summary-coalescent approach). (lu.se)
  • Our novel chemotaxonomic data also support the hypothesis that the extinct Nilssoniales and Bennettitales are closely allied, but only distantly related to Cycadales. (nature.com)
  • These findings reject the hypothesis of independent overwater dispersal onto each island, and support the hypothesis that the Western Archipelago had been colonized via the Batu and Banyak Islands and was subsequently isolated by a vicariant event--most likely related to the Pleistocene changes in sea levels. (escholarship.org)
  • This bridged the diversity between the bryophytes and the Tracheophytes and gave rise to the creation of a monophyletic hypothesis for the evolution of land plants. (nmmra.org)
  • This module aims to develop and expand your understanding of the principles introduced in BIO1411 (Genetics) by considering how molecular genetic tools and techniques are used in ecology, evolution and conservation biology. (exeter.ac.uk)
  • I'm interested in how evolutionary analyses can be combined with experimental research to reconstruct functional evolution of proteins, and to generate testable hypotheses about unknown aspects of protein function. (lu.se)
  • This research profile follows Dr. Rosemary Gillespie to Hawaii as she evaluates hypotheses about the evolution of the colorful happy-face spider. (berkeley.edu)
  • My long-term goal is to develop novel strategies to improve the biological realism of statistical models of molecular sequence evolution. (temple.edu)
  • To enable the exploration of molecular virology and the analysis of viral pathogens I developed "Rapid Assessment of Selection in CLades (RASCL)": a novel application for the rapid assessment of molecular sequence evolution viral clades. (temple.edu)
  • Starting from the genomic sequences and NGS data, we currently concentrate our efforts on structures, interactions, evolution and design, trying to meet the growing needs for a rational synthetic biology. (polytechnique.fr)
  • Towards this end, we have used DNA sequence data to clarify the limits of diversity within Fusarium and to assess the distribution and evolution of toxigenic and pathogenic diversity within this group of fungi. (usda.gov)
  • Tracing the evolution of aneuploid cancers by multiregional sequencing with CRUST. (lu.se)
  • In my group we use and develop bioinformatics tools for analysing molecular sequence data. (lu.se)
  • High-throughput RNA sequencing (RNA-seq) and bioinformatics were used to identify the potential microorganisms. (asm.org)
  • My role in the group, is to bridge the wet and dry lab, working both with molecular biology and bioinformatics. (lu.se)
  • My education at Lund University have given me a broad and solid foundation in both molecular biology and bioinformatics, allowing me to freely travel between the fields and combining them in my research. (lu.se)
  • Statistical analysis of this nuclear gene unambiguously supports the morphology-based Theria hypothesis that excludes monotremes from a clade of marsupials and eutherians. (nih.gov)
  • Gene sequences form the primary basis for understanding the relationships among extant plant groups, but genetic data are unavailable from fossils to evaluate the affinities of extinct taxa. (nature.com)
  • Our study thus demonstrates the feasibility of performing gene co-expression network analysis from cell-free RNA data and its utility in studying hepatocellular carcinoma. (frontiersin.org)
  • An underexplored way of analyzing the rich data obtained from sequencing liquid biopsy-derived cfRNA liquid biopsy is weighted gene co-expression network analysis (WGCNA). (frontiersin.org)
  • However, morphological methods are imprecise for juvenile individuals and fragmentary remains, and molecular methods that rely on particular sex-specific marker loci such as the amelogenin gene suffer from allelic dropout and sensitivity to modern contamination. (blogspot.com)
  • His recent research has been in collaboration with molecular taxonomists, who use gene sequencing to answer questions about evolutionary history. (si.edu)
  • The default search filter 'Available Tracks' searches all tracks that were pre-loaded by the graphical viewer team into your browser session, which may include gene annotation, assembly components, SNP, RNA-Seq, and other types of data. (nih.gov)
  • Experimental data from these NCBI databases can help you validate gene annotation, explore the regulation of different genes or gene splice forms, and create hypotheses for function or disease relevance of your study region. (nih.gov)
  • New articles, gene symbols and full names, gene summaries, Gene Ontology (GO) and Plant Ontology (PO) annotations, germplasms and phenotypes based on those articles are added by data curation scientists to a subset of loci on a weekly basis. (biologists.com)
  • As a proof of concept for candidate gene screening to be routinely performed by ultra high throughput sequencing (UHTs), we analyzed MDH1 in a patient from each of the two families described so far to show linkage between arRP and RP28 . (molvis.org)
  • GOblet: annotation of anonymous sequence data with Gene Ontology and pathway terms. (mpg.de)
  • With the advent of molecular biology and the availability DNA sequencing techniques, using DNA sequences to infer evolutionary and taxonomic patterns started to take hold. (nmmra.org)
  • My big break came when I got a "cultural exchange" grant from Newham Council to go to Poland to learn some molecular biology and I met Professor Erko Stackebrandt who was passing through. (ncl.ac.uk)
  • Mapping Switchgrass Traits with Common Gardens The combination of field data and genetic information has allowed researchers to associate climate adaptations with switchgrass biology. (doe.gov)
  • Amibio (LIX, Ecole Polytechnique) is a research group in computational biology with a primary interest on the molecular levels of organization in the cell, and a strong focus on RNAs. (polytechnique.fr)
  • Our ultimate goal is to provide software tools and platform elements, to formulate and test hypotheses for the sequence/structure/function relationship in molecular biology. (polytechnique.fr)
  • On the other hand, once suitable models are established we apply these computational approaches to several particular problems arising in fundamental molecular biology. (polytechnique.fr)
  • The Arabidopsis Information Resource (TAIR) was established in 1999 with US National Science Foundation funding and the goal of creating a database of genetic and molecular biology data for the model higher plant Arabidopsis thaliana . (biologists.com)
  • Cymon Cox spent three years analysing molecular sequence data to identify which of the competing published hypotheses was best supported and reached the surprising conclusion that it was not the three domains tree but an alternative hypothesis called the eocyte tree (you can read a discussion about the differences between the two trees including a picture of the eocyte tree here ). (ncl.ac.uk)
  • We explore the alternative hypothesis that maintenance in VWM is subserved by temporary activation of the language production system [Acheson, D. J., & MacDonald, M. C. Verbal working memory and language production: Common approaches to the serial ordering of verbal information. (mpi.nl)
  • The data indicated that the potential pathogens identified in the blood samples were associated with translocation from the gut, suggesting the presence of bacteremia, which transcriptome data suggested may induce or aggravate the acute-phase response observed during EVD. (asm.org)
  • RANT applies taxonomic reconciliation to standardize avian taxon names in use in NCBI GenBank, a primary source of genetic data, to a widely used and regularly updated avian taxonomy: eBird/Clements. (datadryad.org)
  • For the remaining unmatched avian names in GenBank, we used Avibase's system of taxonomic concepts, taxonomic descriptions in Cornell's Birds of the World, and DNA sequence metadata to identify corresponding eBird/Clements names. (datadryad.org)
  • Our taxonomic reconciliation is a first step towards rigorous and open-source curation of avian GenBank sequences and is available at GitHub, where it can be updated to correspond to future annual eBird/Clements taxonomic updates. (datadryad.org)
  • They generated or downloaded from Genbank sequence data for those 11638 taxa for 27 genes. (molecularecologist.com)
  • Biodiversity research has advanced by testing expectations of ecological and evolutionary hypotheses through the linking of large-scale genetic, distributional, and trait datasets. (datadryad.org)
  • By comparing the results from two independent datasets (morphological characters and DNA sequences), they have been able to rigorously test the validity of the morphological methods used to estimate phylogenies and inform taxonomic classification. (si.edu)
  • Our development of scalable tools to analyze big datasets of viral pathogen sequences is a critical step forward for global public health. (temple.edu)
  • Then a testable hypothesis/prediction is made, followed by a discussion of what the data reveals (experiment), and finally, a conclusion. (evolutionnews.org)
  • Once a probe kit is developed, anchored hybrid enrichment is superior to traditional PCR-based Sanger sequencing in terms of both the amount of genomic data that can be recovered and effective cost. (biomedcentral.com)
  • ChIP-seq) as well as other molecular genomic data. (nih.gov)
  • Our data strongly supported the monophyly of the genus Paragorgia, the family Coralliidae (precious corals), and a group of undescribed specimens resembling Sibogagorgia. (noaa.gov)
  • Mutational sensitivity tests have shown that the amino acid sequences of many functional proteins must be highly complex and specified in order to function. (evolutionnews.org)
  • A common approach to the mutational screening of candidate genes consists of sequencing their exons and immediate intron boundaries. (molvis.org)
  • In this project, biological members will work to generate in vivo confocal imaging data of the developing spot pattern, as well as generate pupae that express RNAi targeting modiers in the dorsal thorax. (clarkson.edu)
  • Thus, in the absence of modern relatives yielding molecular information, FTIR spectroscopy provides valuable proxy biochemical data complementing morphological characters to distinguish fossil taxa and to help elucidate extinct plant relationships. (nature.com)
  • Furthermore, once a probe kit is developed the cost of a project increases primarily by the number of taxa added (unlike Sanger sequencing which increases by the number of taxa and loci added) [ 13 ]. (biomedcentral.com)
  • Here we help to clarify the taxonomy and evolutionary relationships of the bubblegum octocorals and related taxa by examining molecular data. (noaa.gov)
  • Specified Elective Courses" must exclusively be selected from amongst a list of courses within the categories of either "Pollution Control and Modeling", or "Molecular Ecology and Microbial Biotechnology", or "Socio-Ecological Sustainability" concentration areas. (boun.edu.tr)
  • These questions (and related ones) will be answered in a series of lectures that cover the topic of molecular ecology - which is the application of molecular, population genetic, and increasingly genomic tools to address ecological questions and solve ecological problems. (exeter.ac.uk)
  • was carried out based on molecular, morphological and ecological data. (biomedcentral.com)
  • We then replicated our finding using imputed molecular genetic data from unrelated individuals to show that ~50% of differences in intelligence, and ~40% of the differences in education, can be explained by genetic effects when a larger number of rare SNPs are included. (nature.com)
  • Gaps in our knowledge of morphological, biological, and molecular characters, and the paucity of phylogenetic analyses, within many groups in these families combine to slow progress on the development of identification tools for use in pest detection, exclusion, and management, and in the successful implementation of biological control projects. (usda.gov)
  • When exploring the files deposited in Dryad , I came across a table called "sequence_blacklist" that lists all the sequences that were excluded from the analyses and why. (molecularecologist.com)
  • There is a point where additional morphological characters add little extra value (due to specificity) and the important factor is the quality of the data rather than the quantity. (nmmra.org)
  • 2020) that descended from "Aves" (TaxID: 8782) on 3 May 2020 (Data Repository D2). (datadryad.org)
  • For names that were not an exact match to an Avibase taxonomic concept, we implemented web searches (Google) which often identified minor spelling differences, consulted Cornell's Birds of the World Online ( https://birdsoftheworld.org ), and consulted relevant literature- often the papers that first published those sequence data. (datadryad.org)
  • Databases containing scientific names, distributions, taxonomic literature, and host plant and specimen data pertaining to economically important moths will be expanded and disseminated to the user community. (usda.gov)
  • This gap in our knowledge was addressed in the present study through an integration of morphological and molecular approaches in the investigation of a dataset with larger taxonomic and geographical coverage. (biomedcentral.com)
  • To demonstrate the utility of these markers, we provide haplotype networks, DNA alignments, and summary statistics regarding the sequence variation for the two protein-coding nuclear loci (FEM1 and UbiA). (mdpi.com)
  • These include language-based codes in our DNA, irreducibly complex molecular machines like the bacterial flagellum, 4 and highly specified protein sequences. (evolutionnews.org)
  • With the recent development of computational methods aiming to integrate different levels of information, protein and nucleic acid assemblies studies should provide a better understanding on the molecular processes and machinery occurring in the cell and our research extends to several related issues in comparative genomics. (polytechnique.fr)
  • Whole transcriptome sequencing data was used to assess the distribution of molecular subtypes and genetic alterations in 88 pGBM and 34 sGBM in a Chinese population-based cohort, and the biological progression and prognostic impact were analyzed by combining clinical information. (oncotarget.com)
  • For example, the 2015 annual report showed breast cancer incidence by molecular subtypes using tumor biomarkers for hormone receptor (HR) and human growth factor-neu receptor (HER2) expression. (cdc.gov)
  • A newly compiled data set of nearly complete sequences of the large subunit of the nuclear ribosome (LSU or 28S) sampled from 31 diverse medusozoans greatly clarifies the phylogenetic history of Cnidaria. (doe.gov)
  • Finally, modules can be correlated with phenotype traits and by further studying the module with a high correlation with a trait of interest gain a better understanding of the molecular underpinnings of the trait itself. (frontiersin.org)
  • We use parallel tagged amplicon sequencing to obtain 177 nuclear DNA markers for 35 banded newts sampled throughout the range. (lu.se)
  • When looking at GDV, you'll notice that the tracks from GEO are graph-style, while sequence data from SRA are shown as sequence alignments. (nih.gov)
  • SRA indexes RNA or DNA sequence alignments from high throughput sequencing studies. (nih.gov)
  • One outcome is to provide software or platform elements to predict structural models and functional hypotheses. (polytechnique.fr)
  • Application of next generation sequencing in clinical microbiology and infection prevention. (cdc.gov)
  • 4-6 In Australia, several 2016, using a standard Salmonella hypothesis-generating jurisdictional reference laboratories are developing WGS questionnaire to col ect demographic, clinical and risk capacity and evaluating its utility for routine surveillance factor information, including travel and food consumption of enteric pathogens. (who.int)
  • Types of data used to identify an outbreak include epidemiologic data, clinical/laboratory data, and environmental monitoring data. (cdc.gov)
  • Clinical laboratory data are used to determine if there are additional cases pending confirmation in the area. (cdc.gov)
  • These data are used as the basis to understand how clinical biomarkers change over space and time in patients. (lu.se)
  • carried out a demographic, occupational, clinical and community-based survey in 2 villages in the risk factor data. (who.int)
  • To produce a phylogenetic hypothesis, 559 loci were sampled to produce a final dataset containing 217,702 sites. (biomedcentral.com)
  • These probes hybridize to genomic fragments containing the loci of interest, allowing them to be amplified and sequenced using high-throughput sequencing. (biomedcentral.com)
  • To test our hypotheses, we measured the critical thermal minimum (CT min ) and critical thermal maximum (CT max ) of 100 lines of the Drosophila Genetic Reference Panel (DGRP) and used GWAS to identify loci that explain variation in thermal limits. (frontiersin.org)
  • SAGO statement on newly released SARS-CoV-2 metagenomics data from China CDC on GISAID. (who.int)
  • By combining these measures to define a sensory pattern score, the team member will test the efficacy of this sensory pattern score using data on fully developed sensory bristle patterns from the fruit flies. (clarkson.edu)
  • You will put your lessons into practice through a series of activities taking you through a project - from field samples, to molecular work in the laboratory, to analysing the data to test hypotheses. (exeter.ac.uk)
  • The work contained within this dissertation represents my efforts to create, validate, and test codon models, and to apply them to biologically diverse data sets. (temple.edu)
  • The resulting models are usually designed to be amenable to a probabilistic analysis, which can be used to assess the relevance of models, or test general hypotheses. (polytechnique.fr)
  • Examining the potential use and long-term stability of guaiac faecal occult blood test cards for microbial DNA 16S rRNA sequencing. (cdc.gov)
  • BreathDx - molecular analysis of exhaled breath as a diagnostic test for ventilator-associated pneumonia: protocol for a European multicentre observational study. (cdc.gov)
  • LUDC-ICR has access to some of the largest repositories of well-characterised human islets from patients with and without diabetes in the world, allowing us to test most hypotheses involving pancreatic islet function. (lu.se)
  • La positivité de la PCR augmentait de façon significa- tive avec l'augmentation des taux de séropositivité d'après le test classique d'agglutination en tube et s'élevait à 100 % chez les patients dont les hémocultures étaient positives. (who.int)
  • Sequencing cell-free RNA derived from liquid biopsies has been very promising for the diagnosis of several diseases. (frontiersin.org)
  • This means that I have a role in the research from when we receive tissue biopsies from women with PCOS, sequencing it and performing the data analysis and drawing biological conclusions. (lu.se)
  • Erko had worked with Carl Woese in pioneering the use of ribosomal RNA sequences to investigate evolutionary relationships among prokaryotes. (ncl.ac.uk)
  • A review on machine learning principles for multi-view biological data integration. (cdc.gov)
  • Provides students with the knowledge required to collect, analyze and interpret molecular sequence data using phylogenetic methodologies. (csueastbay.edu)
  • However, since pathogenic mutations can sometimes be located deep within introns, as was recently shown for retinal degeneration genes as well [ 7 , 8 ], we decided to analyze the full MDH1 sequence. (molvis.org)
  • These data also will be used to develop new diagnostic tools (descriptions, images, illustrations, keys) to permit more rapid and accurate identifications. (usda.gov)
  • 5%), may be considered as a diagnostic molecular biomarker of sGBM [ 5 - 9 ]. (oncotarget.com)
  • Implementation of Rapid Molecular Infectious Disease Diagnostics: The Role of Diagnostic and Antimicrobial Stewardship. (cdc.gov)
  • Topics include aligning molecular sequence data, analyzing data with parsimony, likelihood and Bayesian methods, and utilizing phylogenetic information for hypothesis testing. (csueastbay.edu)
  • The introduction of molecular analysis of the relationships between these major groups, in the form of DNA sequence data, has revolutionised the subject in the last twenty years. (nmmra.org)
  • The phylogenetic affinities of the chaetognaths: a molecular analysis. (ox.ac.uk)
  • Furthermore, we augmented cell-free RNA network analysis with single-cell RNA sequencing data which enables the contextualization of the identified network modules with cell-type specific transcriptomes from the liver. (frontiersin.org)
  • To date, many studies have focused on WGCNA analysis of bulk or single-cell RNA (scRNA) sequencing data from tissue samples. (frontiersin.org)
  • Hence, we performed WGCNA analysis on cfRNA data derived from the blood of HCC patients. (frontiersin.org)
  • By taking part in the laboratory work you will learn modern genetic techniques as well as general skills in observation, team work, time management, data analysis and critical thinking which are key to careers in fundamental and applied sciences. (exeter.ac.uk)
  • The second reason this paper grabbed me is the sheer amount of data and analysis effort that went into this study. (molecularecologist.com)
  • Comparative expressed sequence tag analysis. (mpg.de)
  • This module will provide experience in some of these techniques, as well as covering the underlying population genetic principles needed to translate molecular information into biological insight in the field. (exeter.ac.uk)
  • You will learn about practical methods illustrated by diverse empirical examples, and also gain a grounding in the genetic theory needed to interpret molecular data. (exeter.ac.uk)
  • In this article (and the linked assignments and student readings), students examine and interpret data that the team used to study the genes undergoing artificial selection during the development of different dog breeds. (berkeley.edu)
  • The Hong Kong study data are at http://web.hku.hk/,bcowling/influenza/HK_NPI_study.htm The Bangkok dataset is available upon request, and cannot be included in a public repository because it is owned by a third party. (cdc.gov)
  • Mathematical members will be responsible for implementing clustering algorithms to quantify bristle pattern data and detect pattern differences. (clarkson.edu)
  • Codon substitution models can be used to quantify selective pressure on molecular sequences. (temple.edu)
  • Consequently, distributional and trait data are often difficult to link directly to primary DNA sequence data without extensive and time-consuming curation. (datadryad.org)
  • Phoenix has a small team of dedicated data curation scientists, who meticulously curate and update TAIR data, and software engineers, who maintain and update TAIR's database and tools. (biologists.com)
  • CDC's National Hypothesis Generating Questionnaire ) and unstructured questions about exposures, can give clues to develop hypotheses regarding the outbreak source. (cdc.gov)
  • Using Team Science to Build Communities Around Data As the data portals grow and evolve, the research communities further expand around them. (doe.gov)
  • For further insight, research efforts have focused on investigating GBM molecular profiles. (oncotarget.com)
  • Although the data are promising , much of the research has been conducted with mice or come from trials of short-term use in humans. (medscape.com)
  • Surveillance also provides information for generating research hypotheses on cancer causes and outcomes, and for developing and evaluating interventions for cancer prevention and treatment. (cdc.gov)
  • Support Research grants are competed for in order to afford frontline genomic methods and expert data handling. (lu.se)
  • Regular reviews of the data identify patterns in the geographic distribution of illnesses and the time periods when people became ill, facilitating identification of outbreaks. (cdc.gov)
  • Review of the data can identify a pattern of illness suggestive of an outbreak. (cdc.gov)