Hypervalent iodine reagents are capable of oxidizing trivalent phosphorus compounds into pentavalent, by transferring their heteroatom ligands onto phosphorus. (uwaterloo.ca)
These pentavalent phosphorus compounds can have a different reactivity profile than either the hypervalentiodine(III) reagents or the parent phosphorus(III) compounds. (uwaterloo.ca)
The goal of this project is to synthesize pentavalent phosphorus species from trivalent phosphorus compounds using relatively cheap, environmentally benign, hypervalentiodine reagents. (uwaterloo.ca)
Treatment of N H-sulfoximines with pseudocyclic benziodoxole triflate results in N-I bond formation leading to a new type of sulfoximidoyl-containing hypervalentiodine(III) reagents in high yields. (researcher-app.com)
Hypervalent iodine reagents have recently emerged as powerful tools for late-stage peptide and protein functionalization. (chemrxiv.org)
Hypervalent iodine reagents can overcome this hurdle, but are usually employed in stoichiometric amounts. (chemistryviews.org)
Compounds4
In 1990, Magnusson published a seminal work definitively excluding the significance of d-orbital hybridization in the bonding of hypervalent compounds of second-row elements. (wikipedia.org)
Hypervalent tellurium compounds (telluranes) are promising therapeutical agents with negligible toxicities for some diseases in animal models. (unifesp.br)
Recently, extended hypervalent bonds are shown to play an important role in physical, chemical and biological properties of the compounds [ 41 - 50 ]. (hindawi.com)
correspondingly "hypervalent" phosphorous compounds have a total of five bonds to phosphorous. (ccl.net)
Reagent1
On the course of this project, we found that branched allylic CF3 products are accessible by copper-catalyzed trifluoromethylation of allylsilanes with hypervalentiodine reagent (Chem. (europa.eu)
Bonds3
Our strategy to construct the extended hypervalent bonds is to employ the interactions caused by direct orbital overlaps between nonbonded atoms [ 1 - 11 , 19 - 21 ]. (hindawi.com)
It will be great interest if the ethynyl group is joined to the extended hypervalent bonds constructed by the group 16 elements, such as I (Scheme 1). (hindawi.com)
It is shown that the P−O and S−O bonds are highly polarized covalent bonds and, thus, the increase in the valence population following three‐center four‐electron bonding is not sufficient to yield hypervalent phosphorus or sulfur atoms, respectively. (unibe.ch)
Molecule1
In chemistry, a hypervalent molecule (the phenomenon is sometimes colloquially known as expanded octet) is a molecule that contains one or more main group elements apparently bearing more than eight electrons in their valence shells. (wikipedia.org)
Phosphorus2
Phosphorus pentachloride (PCl5), sulfur hexafluoride (SF6), chlorine trifluoride (ClF3), the chlorite (ClO−2) ion, and the triiodide (I−3) ion are examples of hypervalent molecules. (wikipedia.org)
The attempt to actually prepare hypervalent organic molecules began with Hermann Staudinger and Georg Wittig in the first half of the twentieth century, who sought to challenge the extant valence theory and successfully prepare nitrogen and phosphorus-centered hypervalent molecules. (wikipedia.org)
Formally1
Hypervalent molecules were first formally defined by Jeremy I. Musher in 1969 as molecules having central atoms of group 15-18 in any valence other than the lowest (i.e. 3, 2, 1, 0 for Groups 15, 16, 17, 18 respectively, based on the octet rule). (wikipedia.org)
Atoms1
These atoms are referred to as hypervalent. (unibe.ch)
Structures1
Without atomic valence shell expansions, many of these structures provide electronic interpretations for hypervalent 19th century type bond diagrams. (uni-muenchen.de)
Species1
Nevertheless, a 2013 study showed that although the Pimentel ionic model best accounts for the bonding of hypervalent species, the energetic contribution of an expanded octet structure is also not null. (wikipedia.org)
Exist1
Lewis formulas containing a hypervalent central atom exist for all three anions. (unibe.ch)
Bond1
However, for the highly covalent Cl−O bond, most bonding indicators imply a hypervalent chlorine atom. (unibe.ch)
Introduction1
Herein we report a tyrosine bioconjugation methodology for the introduction of hypervalentiodine onto biomolecules under physiological conditions. (chemrxiv.org)
Oxidation1
A Selectfluor ® ‐mediated oxidation converts the catalyst to a hypervalent ArIF 2 species in situ (pictured below). (chemistryviews.org)
Alkynyl2
Based on the results of the aforementioned studies, we present the synthesis of 4-imidazolidinones from various diamides with ethynyl benziodoxolones through double Michael-type addition, which is an unprecedented reaction mode for hypervalent alkynyl iodine compounds (Scheme 1). (gifu-pu.ac.jp)
In conclusion, we achieved the efficient synthesis of 4-imidazolidinones from a variety of diamides by double Michael-type addition, a novel reaction mode for hypervalent alkynyl iodine compounds, and a formal reductive elimination sequence using in situ generated EBX from TMS-EBX or EBX-MeCN. (gifu-pu.ac.jp)
Dive into the research topics of 'Hypervalent Iodine in Synthesis. (aston.ac.uk)
In organic synthesis, the iodation of organic compounds is of great interest and hypervalentiodine compounds are used for their oxidizing properties. (ens-lyon.fr)
Advanced Building Block Synthesis via HypervalentIodine(III) Mediated Amination. (uvigo.gal)
Recently, due to our interest in the development of the reaction with hypervalentiodine compounds, we reported the synthesis of cis-β-amide-vinylbenziodoxolones from sulfonamide, including amino acid derivatives, with an ethynyl benziodoxolone-chloroform complex. (gifu-pu.ac.jp)
Octet rule1
Hypervalent molecules were first formally defined by Jeremy I. Musher in 1969 as molecules having central atoms of group 15-18 in any valence other than the lowest (i.e. 3, 2, 1, 0 for Groups 15, 16, 17, 18 respectively, based on the octet rule). (wikipedia.org)
Reactivity1
Investigation of Reactivity of Hypervalent Iodines Bearing an Imidazolinium Moiety in Oxidative Reaction (Grad. (csj.jp)
Molecules4
Phosphorus pentachloride (PCl5), sulfur hexafluoride (SF6), chlorine trifluoride (ClF3), the chlorite (ClO−2) ion, and the triiodide (I−3) ion are examples of hypervalent molecules. (wikipedia.org)
The attempt to actually prepare hypervalent organic molecules began with Hermann Staudinger and Georg Wittig in the first half of the twentieth century, who sought to challenge the extant valence theory and successfully prepare nitrogen and phosphorus-centered hypervalent molecules. (wikipedia.org)
Chemical Bonding in Hypervalent Molecules Revised. (mit.edu)
The force field supports hypervalent molecules (such as SF6) and transition metal complexes. (nih.gov)
Chemistry3
In chemistry, a hypervalent molecule (the phenomenon is sometimes colloquially known as expanded octet) is a molecule that contains one or more main group elements apparently bearing more than eight electrons in their valence shells. (wikipedia.org)
A revision of the kinetic and mechanistic results of the interaction of carbohydrates of biological importance with hypervalent chromium done by the Bioinorganic Chemistry Research Group at the General Chemistry Area Department of the Biochemistry and Pharmaceutical Science Faculty at the National University at Rosario, during the last ten years is reported. (cognizure.com)
I want to get the latest chemistry news from C&EN in my inbox every week. (acs.org)
Expanded octet1
Nevertheless, a 2013 study showed that although the Pimentel ionic model best accounts for the bonding of hypervalent species, the energetic contribution of an expanded octet structure is also not null. (wikipedia.org)
Synthetic1
New synthetic approach towards avibactam analogues and hypervalentiodine(III)-mediated cyclizations of unsaturated N-alkoxyureas. (viaf.org)