HypothyroidismRadioactive iodineAplastic anaemiaThrombocytopeniaHepaticOvertThyroxinePathophysiologyInhibitionTachycardiaHepatotoxicityClinicalPatientsInteractionsOnsetModalitiesCardiovascularAntithyroid drugsDosesThyroid glandSymptomsTransientPropylthiouracilAmiodaroneTreatmentMedicationDepressionDecreaseVariationLithiumCasesTreatmentsRecurrentChronicSerumClassLevelsDiseaseImmuneTherapeuticFever
Hypothyroidism4
- Levothyroxine (LT4) is the drug of choice for patients who develop lithium-induced hypothyroidism or goiter (when discontinuation of lithium therapy is not feasible). (medscape.com)
- The thyroid gland is underactive with hypothyroidism and overactive with hyperthyroidism. (simplenursing.com)
- Hypothyroidism and hyperthyroidism are commonly encountered in clinical practice. (racgp.org.au)
- Long-term management of patients with hyperthyroidism requires careful consideration of the likely outcomes of treatment including the risk of hypothyroidism. (racgp.org.au)
Radioactive iodine4
- First-line treatment of hyperthyroidism is almost always based on medical therapy (with thioamides, beta-adrenergic blocking agents, glucocorticoids), radioactive iodine or total thyroidectomy, tailored to the patient's diagnosis. (bvsalud.org)
- Conventional management of Interferon-α-Induced Hyper thy roidism (IIH) with radioactive iodine (RAI) may be used when treatment with beta blockers or anti thy roid drugs (ATD), proves ineffective or is contraindicated. (nel.edu)
- Patients with GD are treated with any of the following: antithyroid drugs (ATDs), radioactive iodine (RAI) therapy, or thyroidectomy. (e-jyms.org)
- Treatment modalities for hyperthyroidism include antithyroid medications, radioactive iodine therapy and thyroidectomy. (racgp.org.au)
Aplastic anaemia1
- In humans, phenylbutazone can induce blood disorders like aplastic anaemia, which causes the bone marrow to stop producing enough red and white blood cells and platelets. (studybuff.com)
Thrombocytopenia1
- 3. Hematologic System: Hemolytic anemia, thrombocytopenia, agranulocytosis. (benadryl.com.ph)
Hepatic1
- Acetaminophen-induced hepatotoxicity is manifested as hepatic necrosis, jaundice, bleeding and encephalopathy. (wellrx.com)
Overt2
- Clinical manifestations of hyperthyroidism can vary from subclinical to overt forms. (bvsalud.org)
- A diagnosis of hyperthyroidism can be established by measurement of TSH levels, which will be suppressed with either elevated or normal free thyroxine (T4) and/or triiodothyronine (T3) levels (overt or subclinical hyperthyroidism). (e-jyms.org)
Thyroxine1
- Hyperthyroidism ( overactive thyroid) occurs when the thyroid gland produces too much of the hormone thyroxine. (simplenursing.com)
Pathophysiology1
- The pathophysiology of the condition determines the specific hyperthyroidism variation. (simplenursing.com)
Inhibition3
- [ 8 ] While reports suggested either (1) lack of lithium effects on cAMP synthesis or (2) lithium-induced inhibition of cAMP synthesis, later work in a strain of rat thyroid follicular cells (FRTL-5) and a cell line of Chinese hamster ovary fibroblasts stably transfected with the human thyrotropin receptor (CHO-TSHR) showed significant potentiation by lithium of the cAMP response to exogenous thyrotropin. (medscape.com)
- Clinical pharmacology studies have confirmed the beta-blocking activity of metoprolol in man, as shown by (1) reduction in heart rate and cardiac output at rest and upon exercise, (2) reduction of systolic blood pressure upon exercise, (3) inhibition of isoproterenol-induced tachycardia, and (4) reduction of reflex orthostatic tachycardia. (nih.gov)
- Name the drugs that are used extensively currently due to effective inhibition of inflammatory component of asthma. (findmedarticle.com)
Tachycardia2
- May mask clinical signs (eg, tachycardia) of developing or continuing hyperthyroidism. (medicscientist.com)
- Pacerone (amiodarone HCl) is an antiarrhythmic drug indicated for treatment of recurrent ventricular fibrillation and recurrent hemodynamically unstable ventricular tachycardia only when these conditions have not responded to documented adequate doses of other available antiarrhythmics or when alternative agents could not be tolerated. (rxlist.com)
Hepatotoxicity2
- Both cimetidine and ethanol can affect the severity of acetaminophen-induced hepatotoxicity. (wellrx.com)
- Aspirin-induced hepatotoxicity, presenting as hepatitis, is a dose-related reaction and is usually reversible after discontinuation of aspirin therapy. (wellrx.com)
Clinical5
- After the correct clinical evaluation, oral antidiabetic drugs were added. (bvsalud.org)
- In rare cases, hyperthyroidism may represent a clinical emergency, requiring admission to an intensive care unit due to an acute and severe exacerbation of thyrotoxicosis, known as a thyroid storm. (bvsalud.org)
- Ophthalmopathy may also occur before the onset of hyperthyroidism or as late as 20 years afterward and frequently worsens or abates independently of the clinical course of hyperthyroidism. (msdmanuals.com)
- Adult obese subjects instructed in dietary management and treated with "anorectic" drugs lose more weight on the average than those treated with placebo and diet, as determined in relatively short-term clinical trials. (nih.gov)
- 3. Tiamkao S, Tiamkao Si, Chotmongkol V, Jitpimolmard S. Prevalence and clinical features of myasthenia gravis only and myasthenia gravis with hyperthyroidism. (kku.ac.th)
Patients7
- Vulnerability to infection is extremely high in patients with agranulocytosis, which is the virtual absence of neutrophils in peripheral blood, with ANC typically lower than 100/μL. (medscape.com)
- Granulocytopenia, which can be seen in patients with Graves' disease during treatment with antithyroid agents, could be a self resolving transient episode or can imply the beginning of life threatening agranulocytosis requiring a change in treatment modality. (e-enm.org)
- Diphenhydramine hydrochloride has an atropine-like action, and therefore, should be used with caution in patients with a history of bronchial asthma, increased intraocular pressure, hyperthyroidism, cardiovascular disease, or hypertension. (benadryl.com.ph)
- The magnitude of increased weight loss of drug-treated patients over placebo-treated patients averages some fraction of a pound a week. (nih.gov)
- A rare case of Interferon-alpha-Induced Hyper thy roidism in patients with a chronic hepatitis C with granulocytopenia and transaminasemia treated successfully with radioiodine. (nel.edu)
- Continuing drug treatment for an extended time is now encouraged in patients with a high possibility of remission with low-dose MMZ. (e-jyms.org)
- Patients receiving methotrexate must be well hydrated and, depending on the therapy, may be treated with sodium bicarbonate for urinary alkalinization to enhance drug excretion. (unboundmedicine.com)
Interactions2
- Drug Interactions: MAO inhibitors prolong and intensify the anti-cholinergic effects of antihistamines. (benadryl.com.ph)
- Protein-binding-induced drug interactions with venlafaxine are not expected. (drugs.com)
Onset1
- Aspirin-induced esophagitis is characterized by sudden onset odynophagia, retrosternal pain, and dysphagia. (wellrx.com)
Modalities1
- Although single drugs in one or two classes were available for the treatment of depression several decades ago, multiple therapeutic modalities now exist, often with many agents within each class. (beatcfsandfms.org)
Cardiovascular1
- Pharmacologic activity at these receptors is hypothesized to be associated with the various anticholinergic, sedative, and cardiovascular effects seen with other psychotropic drugs. (drugs.com)
Antithyroid drugs1
- Transient granulocytopenia could be a manifestation of hyperthyroidism itself, or a mild side effect of antithyroid drugs. (e-enm.org)
Doses1
- In clinically useful doses, lithium induces a marked decrease in the release of preformed thyroid hormone (TH) from the thyroid. (medscape.com)
Thyroid gland1
- Primary hyperthyroidism is an endocrine disorder characterized by excessive thyroid hormone synthesis and secretion by the thyroid gland. (bvsalud.org)
Symptoms2
- Abrupt withdrawal may exacerbate symptoms of hyperthyroidism, including thyroid storm. (medicscientist.com)
- Explain that drug will be tapered slowly before stopping to prevent rebound symptoms and adverse effects. (medicscientist.com)
Transient3
- A Case of Transient Granulocytopenia during Treatment of a Patient with Graves' Disease and Type 1 Diabetes Mellitus - Differential Diagnosis from Agranulocytosis by a Single Injection of G-CSF. (e-enm.org)
- Therefore, differentiation of agranulocytosis and transient granulocytopenia, is important, but is not practically easy. (e-enm.org)
- This case confirms a diagnostic tool for differentiating transient granulocytopenia and PTU-induced agranulocytosis. (e-enm.org)
Propylthiouracil1
- Aganulocytosis is a rare, but major complications of the termination drug, propylthiouracil (PTU), requiring prompt termination of the medication, and intensive care. (e-enm.org)
Amiodarone2
- Our Pacerone (Amiodarone HCl) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
- Pacerone® (Amiodarone HCl) Tablets are a member of a class of antiarrhythmic drugs with predominantly Class III (Vaughan Williams' classification) effects, available for oral administration in 100 mg and 200 mg strengths of amiodarone hydrochloride. (rxlist.com)
Treatment4
- The Drug of choice" for the short term treatment of sleep disturbances is: A. Phenobarbitalum B. Diazepamum C. Medazepamum ar oxazepamum D. Clonazepamum E. Nitrazepamum ar triazolamum 19. (findmedarticle.com)
- Which drug is the drug of choice for the treatment of ulcerative colitis? (findmedarticle.com)
- Dapsone remains the main drug for treatment, but it requires monitoring of possible side effects, some potentially lethal. (scielo.br)
- To monitor specific drugs for subtherapeutic, therapeutic, or toxic levels in evaluation of treatment and to detect toxic levels in suspected overdose. (unboundmedicine.com)
Medication1
- Chlorpromazine is a psychiatric medication that belongs to the class of drugs called phenothiazine antipsychotics. (studybuff.com)
Depression1
- The most serious adverse effects of phenylbutazone are related to bone-marrow depression and include agranulocytosis and aplastic anemia. (studybuff.com)
Decrease2
- The latter induces a decrease in the activity of type I 5'-deiodinase enzyme. (medscape.com)
- The rate of weight loss is greatest in the first weeks of therapy for both drug and placebo subjects and tends to decrease in succeeding weeks. (nih.gov)
Variation1
- This kinetic profile results in relatively consistent plasma drug levels with about a fourfold interpatient variation. (sgpharma.com)
Lithium1
- Of note, although lithium stimulates thyrocyte proliferation via activation of assorted pro-proliferative tyrosine kinase cascades and the Wnt/beta-catenin signaling pathway, the aggregate in vitro evidence suggest that this drug is not a bona fide thyroid epithelial carcinogen. (medscape.com)
Cases2
- in other cases of parkinsonism (including drug-induced) in combination with centrally acting anticholinergic agents. (benadryl.com.ph)
- Graves disease (GD) is the most common cause of hyperthyroidism, accounting for more than 90% of cases in Korea. (e-jyms.org)
Treatments1
- Several treatments are available for hyperthyroidism. (simplenursing.com)
Recurrent1
- For the long-term management of recurrent GD, it is important to induce remission by evaluating the patient's drug response, stopping ATDs at an appropriate time, and actively switching to surgery or RAI therapy, if indicated. (e-jyms.org)
Chronic1
- The elimination half-life of oral CARDATEN is approximately 6 to 7 hours and there is no alteration of the kinetic profile of the drug by chronic administration. (sgpharma.com)
Serum1
- Hyperthyroidism is characterized by hypermetabolism and elevated serum levels of free thyroid hormones. (msdmanuals.com)
Class4
- Diethylpropion hydrochloride is a sympathomimetic amine with some pharmacologic activity similar to that of the prototype drugs of this class used in obesity, the amphetamines. (nih.gov)
- Tolerance has been demonstrated with all drugs of this class in which these phenomena have been looked for. (nih.gov)
- Drugs of this class used in obesity are commonly known as "anorectics" or "anorexigenics. (nih.gov)
- Chloroquine phosphate is in a class of drugs called antimalarials and amebicides. (studybuff.com)
Levels2
- If hyperthyroidism is suspected, thyroid hormone levels are first checked. (e-jyms.org)
- thereafter, plasma levels decay with a half-life similar to that of orally administered drug. (sgpharma.com)
Disease1
- The drug produces symptomatic relief only and usually does not alter the disease processes for which it is indicated. (studybuff.com)
Immune1
- [ 3 ] Major causes of acquired neutropenia are infection, drugs (through direct toxicity or immune effects), and autoimmunity. (medscape.com)
Therapeutic1
- Be careful and be sure to specify the information on the section Therapeutic indications in the instructions to the drug Restex directly from the package or from the pharmacist at the pharmacy. (pillintrip.com)
Fever1
- Phenylbutazone is a nonsteroidal anti-inflammatory drug (NSAID) effective in treating fever, pain, and inflammation in the body. (studybuff.com)