The neutralising capacity of the available antivenoms with regard to those venom components that possess haemorrhagic and myonecrotic activity is most probably small, as these effects occur rapidly after the injection of venom (Gutierrez 1990). (vapaguide.info)
Occur1
Although neurotoxic factors can be detected in moccasin venom, clinically significant neurotoxicity does not occur with envenomation by copperheads or cottonmouths. (medscape.com)
Components1
Moccasin venom is complex, with nearly 50 identified components. (medscape.com)
Envenomation4
CROFAB is a sheep-derived antivenin indicated for the management of adult and pediatric patients with North American crotalid envenomation. (nih.gov)
For a more detailed discussion of coagulopathy induced by pit viper venom, see Rattlesnake Envenomation . (medscape.com)
However, this could exacerbate local swelling, which is almost always present in crotalid envenomation. (medscape.com)
INTRODUCTION: Compartment syndrome (CS) is a rare but serious complication after crotalid envenomation in the United States. (bvsalud.org)
Pathophysiology1
Explain the pathophysiology of the venom from cottonmouth snakes and its effects on local tissue. (nih.gov)
Crotalinae2
The term crotalid is used to describe the Crotalinae subfamily (formerly known as Crotalidae) of venomous snakes which includes rattlesnakes, copperheads and cottonmouths/water moccasins. (nih.gov)
The distribution and relative potency of post-synaptic neurotoxic activity within Crotalinae venoms has been the subject of less investigation in comparison with Elapidae snake venoms. (bvsalud.org)
Viper venom1
Pit viper venom is used to facilitate the capture and digestion of prey and can cause significant toxicity in humans. (nih.gov)
Snakes1
red on black, venom lack" is commonly used to distinguish coral snakes from nonvenomous species, but there are many exceptions. (medscape.com)
Patients1
Do not administer CROFAB to patients with a known history of hypersensitivity to any of its components, or to papaya or papain unless the benefits outweigh the risks and appropriate management for anaphylactic reactions is readily available. (nih.gov)
Effects1
Nonsteroidal anti-inflammatory drugs (NSAIDs) are not recommended because of their potential hematologic effects, which could compound with venom-induced coagulopathies. (medscape.com)