Hyperplasia was significantly increased. Medical search. Frequent questions

Benign prostatic hyperplasia (BPH), also known as benign prostatic hypertrophy, is a histologic diagnosis characterized by proliferation of the cellular elements of the prostate, leading to an enlarged prostate gland. (medscape.com)
Management of Benign Prostatic Hyperplasia: Could Dietary Polyphenols Be an Alternative to Existing Therapies? (frontiersin.org)
The incidence of benign prostatic hyperplasia (BPH) is gradually on the increase. (frontiersin.org)
Benign prostatic hyperplasia (BPH) is the most common urological condition among elderly men, affecting approximately half of men over 80 years of age. (frontiersin.org)
Perito Urology now offers a new procedure proven to significantly improve the quality of life for those suffering Benign Prostatic Hyperplasia (BPH) better known as enlarged prostate. (peritourology.com)
A 3 month study published in the British Journal of Urology by B.-E. Carbin, B. Larsson, and O. Lindahl concluded that phytosterols significantly improved the symptoms of benign prostatic hyperplasia [2] . (consumerhealthdigest.com)
One of its main pathologies is benign prostatic hyperplasia (BPH), the most common benign disease in older men. (intechopen.com)
In this organ, estrogens promote or limit cell proliferation depending on the activated receptor, with implications for the pathophysiology of benign prostatic hyperplasia (BPH) and prostate cancer (PCa). (intechopen.com)
Unfortunately, PSA levels can also be elevated due to confounding conditions like benign prostate hyperplasia (BPH) and prostatitis. (carislifesciences.com)
Benign Prostatic Hyperplasia (BPH) refers to the noncancerous enlargement of the prostate gland. (trionds.com)
[ 7 ] The PSA level also tends to rise in men with benign prostatic hyperplasia (BPH) and is a good marker for prostate volume. (medscape.com)
K17 was not detected in the epithelial cells of benign glandular lesions, but groups of cuboidal cells, residing beneath the epithelial layer of benign glands, were frequently positive for K17, especially in cases of microglandular hyperplasia. (medscape.com)

Increased airway smooth muscle (ASM) mass due to hyperplasia/hypertrophy contributes significantly to overall airway remodeling and correlates with decline in lung function. (harvard.edu)
The incidences of hepatocyte hypertrophy and lymphoid hyperplasia of the spleen in the 10 and 25 mg/kg/day groups, chronic inflammation of the lung in the 3, 10, and 25 mg/kg/day groups, and mammary gland hyperplasia, suppurative inflammation of the skin, and ulcer of the skin in the 25 mg/kg/day group were significantly increased compared to the vehicle control group. (nih.gov)
Moreover, as a result of the obstructive process, increased collagen deposition and muscle hypertrophy can significantly thicken the bladder wall. (medscape.com)
Hypertrophy and hyperplasia of the detrusor muscle and increases in connective tissue limit bladder compliance during filling. (medscape.com)

Antibodies against transforming growth factor-beta 1 suppress intimal hyperplasia in a rat model. (jci.org)
Intimal hyperplasia is induced by therapeutic vascular interventions and often results in clinically important narrowing of the vascular lumen. (jci.org)
We conclude that TGF-beta 1 is causally involved in the development of intimal hyperplasia, and that anti-TGF-beta 1 agents may be useful in achieving at least partial control of this condition. (jci.org)
Alteration of the HIF pathway may contribute to vascular graft failure through the formation of intimal hyperplasia. (ox.ac.uk)

A mutation or deletion of any of the genes that code for enzymes involved in cortisol or aldosterone synthesis results in congenital adrenal hyperplasia. (medscape.com)

Thickening of the forestomach mucosa (hyperplasia and hyperkeratosis) and lymphoid depletion of the thymus in exposed males and females and testicular degeneration in exposed males, observed primarily in the 12,500 and 25,000 ppm groups, were associated with decreased survival and increased morbidity in these groups. (nih.gov)
1998). Airway bronchial-associated lymphoid tissue hyperplasia, and peribron- responses have been induced after inhalation challenge with chiolar plasma cell infiltrates. (cdc.gov)

Obese OA mice had a more severe cartilage destruction and increased levels of synovial apoptotic cells (ACs) than OA mice in the control group. (elifesciences.org)
The synovial fluid concentration of interleukin-1 receptor antagonist (assessed by use of mouse anti-interleukin-1 receptor antagonist antibody) was increased following treatment with ACS. (avma.org)

Cleared by the U.S. Food and Drug Administration in September 2013, clinical research has shown that patients receiving the UroLift® System implants reported rapid improvement in their symptoms including increased urinary flow rates and preserved sexual function. (peritourology.com)
It has an 8-10% prevalence in men 40 years of age and older, increasing to more than 90% in men over 90 years, with lower urinary tract symptoms being one of its main complications. (intechopen.com)
Existing treatments significantly reduce clinical symptoms, including lower urinary tract symptoms. (intechopen.com)
A Whole Health approach to women's health incorporates complementary and integrative practices, including supplements and herbal remedies, to improve health and well-being and manage symptoms related to underlying conditions. (va.gov)
A special garlic extract (Kastamonu Garlic) reduced prostate size and significantly improved urinary symptoms in one study. (clarksnutrition.com)
While it isn't a life-threatening condition, it can significantly impact a man's quality of life due to the urinary symptoms it presents. (trionds.com)
BPH can cause a range of urinary symptoms that can significantly impact day-to-day living. (trionds.com)
The most common symptoms include increased urinary frequency, urinary urgency, and the sensation of incomplete bladder emptying. (trionds.com)

The incidence of mineralization of the renal papilla was significantly increased in 1000 ppm males. (europa.eu)
Treatment with sodium saccharin significantly increased the incidence and extent of preneoplastic lesions, papillary or nodular (PN) hyperplasia, in rats treated with BBN for 4 weeks. (nih.gov)
Administration of 5% aspartame or 5% stevioside in the diet did not, however, affect the incidence or extent of PN hyperplasia in BBN-treated rats. (nih.gov)
At present, the incidence of obesity continues to increase ( Caballero, 2019 ). (elifesciences.org)
PSA-screening testing led to a significant increase in the incidence of prostate cancer, peaking in 1992. (mlo-online.com)
In contrast, late menopause is associated with an increase in the incidence of breast cancer. (who.int)
Although screening programs have been very effective in decreasing the incidence of SCC by as much as 80%, [ 8 ] studies have shown a contrasting increase in the incidence of cervical adenocarcinoma, particularly in younger women. (medscape.com)

NTP stated that alpha-methylstyrene showed some evidence of carcinogenicity based on the increased incidences of renal tubule adenomas and carcinomas (combined) in male rats, while there was no evidence of carcinogenicity in female rats. (europa.eu)
The in vivo neointimal hyperplasia model was established 2 weeks after the carotid artery balloon injury in SHR rats. (hindawi.com)
Absorption, distribution, and excretion Rats fed diets containing 4.1% lipids extracted from chlorine- treated flour showed a decrease in polyunsaturated fatty acids and a corresponding increase in palmitic, oleic, and palmitoleic acids in fat depots when compared with controls receiving 4.1% lipid from untreated flour. (inchem.org)
Perfluoroheptanoic acid induces Leydig cell hyperplasia but inhibits spermatogenesis in rats after pubertal exposure. (bvsalud.org)

The phenotypic transformation of proliferation and migration in vascular smooth muscle cells (VSMCs) from media to intima is the basic pathology of neointimal hyperplasia after angioplasty in hypertensive patients. (hindawi.com)
Neointimal hyperplasia after vascular injury plays a critical role in the process of vascular restenosis, but the mechanism has not been fully elucidated yet [ 3 ]. (hindawi.com)
Via AT1a receptor, AngII increased oxidative stress, which is a critical regulator of VSMC proliferation and migration in hypertension and vascular remodeling [ 6 - 8 ]. (hindawi.com)
Increased activation of the HIF pathway causes aberrant expression of angiogenic factors contributing to the formation and maintenance of vascular malformations. (ox.ac.uk)

Immunohistochemical staining showed that two TGF-beta 1-induced extracellular matrix components, EDA + fibronectin and versican, were greatly increased in the untreated neointimal lesions, but were almost completely absent from the lesions of the anti-TGF-beta 1-treated animals. (jci.org)
It is unknown whether fisetin would inhibit neointimal hyperplasia. (hindawi.com)
The rat thoracic aortic smooth muscle cells (A10 cells) stimulated by AngII were used as the in vitro neointimal hyperplasia model, where AngII significantly induced the proliferation and migration in A10 cells. (hindawi.com)
Administration of fisetin (ip 3 mg/kg daily for 2 weeks) right after the injury significantly increased PON2 expression in the artery, inhibiting ROS production, and efficiently reduced carotid neointimal hyperplasia. (hindawi.com)
These results indicate that fisetin increases the expression of antioxidant PON2 via activation of PPAR γ , reducing oxidative stress, inhibiting VSMC proliferation and migration, and alleviates neointimal hyperplasia after intimal injury. (hindawi.com)

The chlorine content of adipose tissue was, however, only slightly increased. (inchem.org)
Rarely, but significantly, CoolSculpting can cause a condition known as paradoxical adipose hyperplasia. (magnoliabodysculpting.com)
It has been observed that cryolipolysis is more likely to cause paradoxical adipose hyperplasia in male individuals. (magnoliabodysculpting.com)
To eliminate the increased fat cells, those affected by paradoxical adipose hyperplasia may require corrective treatment, such as liposuction. (magnoliabodysculpting.com)

Six of 10 rabbits in the 45mg/kg group had hepatocyte necrosis and bile duct hyperplasia. (cdc.gov)

In the nose, the incidences of basal cell hyperplasia were significantly increased in all exposed groups of males and females, and the incidences of degeneration of the olfactory epithelium were increased in 1000 ppm males and females and 300 ppm females. (europa.eu)
The incidences of hepatocellular adenoma or carcinoma (combined) were significantly increased in the 100 and 600 ppm males and in all exposed groups of females. (europa.eu)
Final mean body weights and mean body weight gains of all exposed groups except 1,562 ppm females were significantly lower than those of the controls. (nih.gov)
the final mean body weight of 12,500 ppm females and the mean body weight gains of 12,500 ppm males and females were significantly lower than those of the controls. (nih.gov)
Absolute and relative liver weights of 3,125, 6,250, and 12,500 ppm males and of 12,500 ppm females and the absolute and relative right kidney weights of 12,500 ppm males were significantly lower than those of the controls. (nih.gov)
Final mean body weights and mean body weight gains of all groups of exposed males and of females exposed to 1,562, 3,125, and 6,250 ppm were significantly lower than those of the controls. (nih.gov)
Absolute and relative adrenal gland weights of exposed males and of 3,125 and 6,250 ppm females were significantly greater than those of the controls. (nih.gov)
NOEL = 20 mg/kg (Females at 80 mg/kg had increased perineal soiling (satellite & main group). (fluoridealert.org)
NOEL = 80 mg/kg (There was a significantly decreased bodyweight gain in both sexes at 250 mg/kg (primarily females). (fluoridealert.org)
Relative (to bodyweight ) liver and kidney weights were significantly increased in females at 250 mg/kg. (fluoridealert.org)

Increased HIF-1α may contribute to atherosclerosis through alteration of smooth muscle cell proliferation and migration, angiogenesis, and lipid metabolism. (ox.ac.uk)
Our study revealed that Ang II influences EC cells in terms of cancer-related processes, and is responsible for increased proliferation, reduction in apoptosis, increased mobility and modulation of adhesion potential. (spandidos-publications.com)
This proliferation may be mediated by increasing BCL2 and phosphorylation of AKT, ERK1/2, and JNK, and decreasing BAX level. (bvsalud.org)

Other follicles showed signs of hyperactivity manifested by the presence of microfollicles, follicular epithelial cell stratification, and extensive vacuolated colloid, with an increase in the number of lysosomes. (poisonfluoride.com)
Goblet cell hyperplasia and epithelial thickening were evident after just 4 d. (monash.edu)

Consistent with the hyaline droplet accumulation, an exposure related increase in alpha2u-globulin was detected in the kidneys of males exposed to alpha-methylstyrene. (europa.eu)
As these kinds of health effects data become available and methods to assess levels of significant human exposure improve, these MRLs will be revised. (cdc.gov)
Strong cytochrome P450 (CYP) 3A inhibitors may increase exposure to doxazosin and increased risk of hypotension. (nih.gov)
Increasing youth's awareness about the adverse health effects of excessive noise exposure and simple preventive measures to reduce risk can help prevent or reduce NIHL. (cdc.gov)

additional males with focal hyperplasia or adenoma were identified. (europa.eu)
The incidences of renal tubule adenoma and carcinoma (combined) in the 1000 ppm males were significantly greater than those in the chamber controls when the single and step sections were combined. (europa.eu)

The screening and diagnosis of PCa would be significantly improved by identifying biomarkers that are both highly specific and sensitive as well as easily surveyed from the blood or urine. (carislifesciences.com)
Volatile aldehydes are enriched in esophageal adenocarcinoma (EAC) patients' breath and could improve early diagnosis, however the mechanisms of their production are unknown. (nature.com)

Tissue and breath concentrations of the medium-chain alkanal decanal are correlated, and increased decanal is linked to reduced ALDH3A2 expression, TP53 deletion, and adverse clinical features. (nature.com)

In pulmonary hypertension, HIF-1α contributes to the increase of intracellular K(+) and Ca(2+) leading to vasoconstriction of pulmonary smooth muscle cells. (ox.ac.uk)

While estradiol levels are generally preserved, follicle stimulating hormone levels (FSH) increase slightly. (medscape.com)
It significantly increased serum testosterone , luteinizing hormone , and follicle-stimulating hormone levels at a dose of 100 mg/kg without affecting serum estradiol levels. (bvsalud.org)

The main effects of parathyroid hormone are to increase the concentration of plasma calcium by increasing the release of calcium and phosphate from bone matrix, increasing calcium reabsorption by the kidney, and increasing renal production of 1,25-dihydroxyvitamin D-3 (calcitriol), which increases intestinal absorption of calcium. (medscape.com)

In chronically challenged mice, these changes persisted and, in addition, subepithelial collagen deposition was significantly increased. (monash.edu)
This collagen deposition was associated with a failure to upregulate matrix metalloproteinase (MMP)-2, in conjunction with increased transforming growth factor-beta and MMP-9 expression. (monash.edu)
Keratinocyte hyperproliferation, condensed dermal collagen, and mononuclear perivascular infiltrate increased with lymphedema stage, which suggested progressive chronic inflammation and fibrosis. (cdc.gov)

Alterations in the thyroid structure were further confirmed by the results of the hormonal assay, which showed a significant and a highly significant decrease in serum T4 and T3, respectively, with a subsequent increase in TSH. (poisonfluoride.com)
Free and total serum thyroxine (T4) were significantly decreased in the 10 and 25 mg/kg/day groups, and total triiodothyronine (T3) was significantly decreased in the 25 mg/kg/day group. (nih.gov)

High levels of K17 expression were significantly associated with decreased patient survival. (medscape.com)

Dr. Paul Perito, renowned thought leader in Men's Sexual Health said, "Perito Urology is looking forward to changing the lives of many men through the UroLift® procedure which is proven to improve urinary flow rates and preserve sexual function. (peritourology.com)

While these conventional drugs have been found to be efficacious in the treatment of BPH, the adverse effects associated with them, ranging from impotence and gynaecomastia to orthostatic hypotension, abnormal ejaculation amongst others, have led to increased search for alternative means of managing this disease. (frontiersin.org)

Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions of severe hypertension can provide substantial benefit. (nih.gov)
While some subcutaneous fat is required for proper body function, excessive amounts have been linked to an increased risk of severe conditions like cardiovascular disease and type 2 diabetes. (magnoliabodysculpting.com)

In conclusion of the three mutagenicity studies, DT827B was considered to cause no mutagenicity under the conditions used in the present experiments except the increase in polyploidy, which probably is due to a toxic effect of the compound. (go.jp)
In conclusion, PFHpA induces Leydig cell hyperplasia due to the increase in the secretion of luteinizing hormone through negative feedback after down-regulating the expression of steroidogenic enzymes and inhibiting testosterone production in individual Leydig cells . (bvsalud.org)

This heightened sensitivity to cortisol stimulates fat cells to further increase in size. (wikipedia.org)

The absolute kidney weight of the 25 mg/kg/day group was also significantly increased compared to the vehicle control group. (nih.gov)

Saw Palmetto also has powerful antioxidants which help repair damage to the prostate and bladder and improve functioning. (consumerhealthdigest.com)
When the urine remains in the bladder for extended periods due to poor bladder emptying, it creates a breeding ground for bacteria, increasing the risk of infection. (trionds.com)
Practicing pelvic floor exercises, also known as Kegel exercises, can strengthen the muscles around the prostate and improve bladder control. (trionds.com)
As patients with PUV age, bladder decompensation may develop, resulting in detrusor failure and increased bladder capacity. (medscape.com)

When soft-wheat flours were treated with chlorine, the chlorine content of the lipids was markedly increased, that of water-soluble components to a lesser extent, and of the gluten only slightly. (inchem.org)

This platform has been used to identify a plasma-based exosome biosignature for prostate cancer (PCa) that is superior to current tests, which rely on increased levels of either PSA in the blood or elevated levels of the PCA3 transcript in the urine. (carislifesciences.com)
Taking garlic can improve cholesterol levels and help prevent heart disease. (clarksnutrition.com)
Growth hormone levels were significantly and progressively elevated in both types of smoking. (who.int)
As men grow older, testosterone levels decrease, and estrogen levels increase. (trionds.com)

If obesity is redefined using WHR instead of BMI, the proportion of people categorized as at risk of heart attack worldwide increases threefold. (wikipedia.org)
In postmenopausal women, obesity increases the risk of breast cancer. (who.int)

Semen acid- phosphatase activity was increased in the 45mg/kg group. (cdc.gov)

EDB did not significantly affect male fertility or cause any fetal malformations. (cdc.gov)
Congenital anomalies are also a leading cause of fetal death and an increasing cause of neonatal mortality in countries undergoing the epidemiological transition (for example, China). (who.int)

While conventional drugs such as the α1-adrenergic receptor antagonists and 5α-reductase inhibitors have been found to be useful in the treatment of BPH, the adverse side effects associated with their usage, have led to increased search for alternative means of managing this disease. (frontiersin.org)

Almost all of the additional chlorine was in water-solubles and gluten (including lipid), and treatment did not significantly increase the chlorine in the prime starch. (inchem.org)
A 2009 study indicated that the use of a case manager for the treatment of patients with hip fractures can lead to more frequent use of appropriate osteoporosis treatment and may result in fewer fractures, increased life expectancy, and significant health-care cost savings. (medscape.com)

Results -Osteochondral fragmentation induced significant increases in various variables indicative of joint pain and disease. (avma.org)
Facial asymmetry is relatively common, but it becomes a disease when condylar hyperplasia is involved. (scielo.cl)
PCOS is associated with an increased risk of developing diabetes mellitus and cardiovascular disease. (va.gov)
Region present for the first time at stages two and three, indicating the need for increased community awareness and early detection of the disease. (who.int)

Results -Exercised horses were significantly lamer at the end of the study than control horses. (avma.org)

and an increased number of Treg cells in draining lymph nodes. (nih.gov)
Rosiglitazone, a PPAR γ agonist, could increase PON2 expression in A10 cells, while the PPAR γ inhibitor prevented the effect of fisetin on PON2. (hindawi.com)
Also, hyperplasia was observed in parafollicular cells and confirmed statistically. (poisonfluoride.com)
In hyperplasia, the number of cells increases while the size of the cells themselves does not. (scielo.cl)
PFHpA induced Leydig cell hyperplasia (increased number of CYP11A1 -positive Leydig cells ) at a dose of 100 mg/kg, but down-regulated the expression of Cyp11a1 , Hsd3b1, and Cyp17a1 in individual Leydig cell pe se and up-regulated the expression of Fshr in the Sertoli cell pe se. (bvsalud.org)
At this point, the treated area's fat cells do the opposite of what was hoped for and increase. (magnoliabodysculpting.com)

[ 147 ] In addition, a physician reminder in conjunction with a patient risk assessment strategy can result in a reduction in patient fractures and an increase in osteoporosis therapy. (medscape.com)
intends to inform the audience--mostly occupational health practitioners, researchers, policy- and decision-makers, employers, and workers in potentially hazardous workplaces--so that improved risk-management practices may be developed to better protect workers from the risks of skin contact with the chemicals of interest. (cdc.gov)
A positive family history increases the risk of breast cancer in first- line relatives (mother, sister, or daughter). (who.int)
A small increase in the risk of breast cancer has been noted in users of oral contraceptives. (who.int)
The risk increases with duration of hormone use, while it decreases significantly following cessation of the therapy. (who.int)
Consumption of fruits and vegetables may reduce the risk of developing breast cancer, while dietary intake of fat seems to increase the risk. (who.int)
It might increase the risk of bleeding during and after surgery. (medlineplus.gov)
Taking lycopene along with medications that also slow blood clotting might increase the risk of bruising and bleeding. (medlineplus.gov)
Lycopene might slow blood clotting and increase the risk of bleeding. (medlineplus.gov)
Taking it with other supplements with similar effects might increase the risk of bleeding in some people. (medlineplus.gov)

The use of high doses increases the likelihood that potentially significant toxic effects will be identified. (fluoridealert.org)

Semen pH and ejaculate volume were significantly decreased in a dose related manner. (cdc.gov)
pulmonary EROD activity was increased only at the 25 mg/kg/day dose. (nih.gov)

Examination of the role of TGF-beta 1 in a rat carotid artery injury model confirmed the presence of a previously reported increase in TGF-beta 1 mRNA in the media of injured arteries. (jci.org)
The expression of HIF-1α is significantly elevated in aortic aneurysms compared with nonaneurysmal arteries. (ox.ac.uk)

As lymphedema progresses, the frequency of ADLA episodes generally increases (11,12). (cdc.gov)

The majority of these newly diagnosed cancers were clinically localized, which led to an increase in radical prostatectomy and radiation therapy - aggressive treatments intended to cure these early-stage cancers. (mlo-online.com)

Thus, we present a model for increased exhaled aldehydes based on endogenous accumulation from reduced detoxification, which also causes therapeutically actionable genotoxicity. (nature.com)

In core study animals, the mean body weight gains of 10 and 25 mg/kg/day groups and the final mean body weight of the 25 mg/kg/day group were significantly increased compared to the vehicle control group. (nih.gov)
At 3 months, the absolute and relative spleen weights of the 3, 10, and 25 mg/kg/day groups, liver weights of the 10 and 25 mg/kg/day groups, and lung weights of the 25 mg/kg/day group were significantly increased compared to the vehicle control group. (nih.gov)

Anatomy23

Organisms8

Diseases49

Chemicals and Drugs13

Analytical, Diagnostic and Therapeutic Techniques and Equipment17

Phenomena and Processes4

Disciplines and Occupations1

Technology, Industry, Agriculture1

Benign12

Hypertrophy4

Intimal hyperplasia4

Adrenal hyperplasia1

Lymphoid2

Synovial2

Symptoms8

Incidence7

Rats4

Vascular4

Neointimal5

Adipose4

Hepatocyte1

Females10

Proliferation3

Epithelial2

Exposure4

Males2

Diagnosis2

Clinical1

Contributes1

Follicle stimulating ho2

Renal1

Collagen3

Serum2

Associated with decreased1

Urinary1

Hypotension1

Severe2

Conclusion2

Cortisol1

Kidney1

Bladder4

Extent1

Levels4

Obesity2

Acid1

Fetal2

Receptor1

Treatment2

Disease4

Results1

Cells6

Risk10

Effects1

Dose2

Arteries2

Frequency1

Radiation therapy1

Model1

Group2