• atypical adenomatous hyperplasia and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia. (ersjournals.com)
  • In addition of the categories of squamous dysplasia and carcinoma in situ , two additional lesions were added to the group of pre-invasive lesions: atypical adenomatous hyperplasia (AAH) and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). (ersjournals.com)
  • A multi-step carcinogenesis hypothesis suggests a progression from pulmonary atypical adenomatous hyperplasia (AAH) through AIS to invasive adenocarcinoma (AC), but to date this has not been formally demonstrated. (wikipedia.org)
  • There are simple, complex (adenomatous without atypia), and atypical hyperplasia representing also the ascending risk of becoming malignant. (lookformedical.com)
  • Chromosome 17p is frequently involved, which contains the p53 gene known to confer a poor prognosis in endometrial cancers when mutated or deleted, and which plays an important role in the transition to carcinoma from atypical hyperplasia. (medmuv.com)
  • Is the combination of bilateral pulmonary nodules and mosaic attenuation on chest CT specific for DIPNECH? (biomedcentral.com)
  • On chest CT, DIPNECH exhibits bilateral pulmonary nodules and mosaic attenuation in most patients. (biomedcentral.com)
  • We searched the Mayo Clinic records from 2015 to 2019 for patients with bilateral pulmonary nodules and mosaic attenuation on CT who had a diagnostic lung biopsy. (biomedcentral.com)
  • Various disorders can manifest the CT pattern of bilateral pulmonary nodules together with mosaic attenuation, and this combination is nonspecific for DIPNECH, which was found in only 10% of our cohort. (biomedcentral.com)
  • Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is characterized by multifocal proliferation of pulmonary neuroendocrine cells. (biomedcentral.com)
  • Systemic sclerosis is a rare chronic disease of unknown cause characterized by diffuse fibrosis and vascular abnormalities in the skin, joints, and internal organs (especially the esophagus, lower gastrointestinal tract, lungs, heart, and kidneys). (msdmanuals.com)
  • Rarely, a large or infiltrative tumor burden limits alveolar function (e.g., diffuse lepidic adenocarcinoma or lymphangitic carcinomatosis). (sts.org)
  • SMARCB1 deficient sinonasal carcinomas are rare neoplasms, classified under sinonasal undifferentiated carcinomas by the fourth edition of the World Health Organization (WHO) classification of head and neck tumors. (bvsalud.org)
  • Macroscopically, ulcerative carcinomas are poorly-differentiated adenocarcinomas, which invade deeply into the stomach wall. (poznayka.org)
  • Microscopically, fungating or polypoid carcinomas are well-differentiated adenocarcinomas, commonly papillary type. (poznayka.org)
  • Kirsten (Ki)-ras activating point mutations in codons 12 and 13 have been implicated in the development of atypical endometrial hyperplasias and endometrioid carcinomas in Japanese women, as well as in colon cancers. (medmuv.com)
  • As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
  • Microscopically, early gastric carcinoma is a typical glandular adenocarcinoma, usually well-differentiated. (poznayka.org)
  • Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). (samatashkhis.com)
  • In lymphomas I have conducted studies in rare aggressive primary cutaneous tumors such as gamma/delta T cell lymphoma (expanding the description of the epidermotropic variant) as well as more indolent entities such as lymphomatoid papulosis (type D) and CD4-positive small to medium size T cell lymphoproliferative disorders. (mdanderson.org)
  • The use of MRI and contrast agents has improved the accuracy of non-invasive diagnosis of these tumors, and especially in the identification of specific molecular subtypes of liver adenoma. (golearnweb.com)
  • Salivary Gland Polymorphous Adenocarcinoma: Clinicopathological Features and Gene Alterations in 36 Japanese Patients. (nagoya-u.ac.jp)
  • As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. (mdanderson.org)
  • An infection IN CCA CCA shows the histological quality of adenocarcinoma from the bile-duct epithelial cells, and it's been recommended that the development to cancers is comparable to that which is normally seen in the intestinal kind of gastric cancers: from hyperplasia to Fluopyram metaplasia, dysplasia, and, eventually, the introduction of adenocarcinoma. (baxkyardgardener.com)
  • Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. (cancerindex.org)
  • Through his research, Dr. Chung is studying how imaging can play a more significant role in patients with chronic lung diseases, specifically, interstitial lung disease, pulmonary fibrosis, occupational lung disease and nontuberculous mycobacterial pneumonia. (uchicago.edu)
  • Many studies now justify that AAH is a precursor to adenocarcinoma 4 - 14 . (ersjournals.com)
  • Type-I cystic adenomatoid malformation (CAM) has recently been identified as a precursor lesion for the development of mucinous AIS, but these cases are rare. (wikipedia.org)
  • In this Perspectives article, we review and synthesize these recent lines of evidence and propose a working nomenclature for SCLC subtypes defined by relative expression of these four factors. (cancerindex.org)
  • Defining the unique therapeutic vulnerabilities of these subtypes of SCLC should help to focus and accelerate therapeutic research, leading to rationally targeted approaches that may ultimately improve clinical outcomes for patients with this disease. (cancerindex.org)
  • Adrenal myelolipoma is a rare benign tumor originating from the adrenal cortex. (journalajrru.com)
  • The Noguchi classification system for small adenocarcinomas has received considerable attention, particularly in Japan, but has not been nearly as widely applied and recognized as the WHO system. (wikipedia.org)
  • The immune response is localized to the proximal small intestine and causes the characteristic histologic findings of villous atrophy, crypt hyperplasia, and intraepithelial lymphocytosis. (lecturio.com)
  • Although meningiomas commonly arise in locations where meningothelial cells are found, the embryonic origin of intraventricular and pulmonary meningiomas are intriguing. (medscape.com)
  • Hyperplasia of the mucous membrane of the lips, tongue, and less commonly, the buccal mucosa, floor of the mouth, and palate, presenting soft, painless, round to oval sessile papules about 1 to 4 mm in diameter. (lookformedical.com)
  • Most cases of paraneoplastic AN involve an adenocarcinoma,[5] most commonly one arising in the gastrointestinal tract (stomach or liver[3] ) and less commonly in the lungs, ovaries, uterus, breasts, kidneys, prostate or bladder. (medscape.com)
  • Adenocarcinoma in situ (AIS) of the lung -previously included in the category of "bronchioloalveolar carcinoma" (BAC)-is a subtype of lung adenocarcinoma. (wikipedia.org)
  • citation needed] The most recent 2015 World Health Organization (WHO) and 2011 International Association for the Study of Lung Cancer (IASLC) / American Thoracic Society (ATS) guidelines refine pulmonary adenocarcinoma subtypes in order to correspond to advances in personalized cancer treatment. (wikipedia.org)
  • Microscopically, it may be an adenocarcinoma or signet-ring cell carcinoma, extensively infiltrating the stomach wall, but due to marked desmoplasia cancer cells may be difficult to find. (poznayka.org)
  • Imaging, always based on clinical information, is an essential tool in the diagnosis of pulmonary diseases in patients with symptomatic AIDS. (webcir.org)
  • Thymus hyperplasia is present in two thirds of all patients with myasthenia gravis. (lookformedical.com)
  • The type of pulmonary condition to be developed by AIDS patients will depend on the stage of disease, which is generally determined based on the CD4 lymphocyte count. (webcir.org)
  • The superficial type may further be of flat, elevated to depressed subtypes. (poznayka.org)
  • Although the entity of AIS was formally defined in 2011, it represents a noninvasive form of pulmonary adenocarcinoma which has been recognized for some time. (wikipedia.org)
  • This case is being reported to highlight the diagnostic challenge associated with this rare entity. (bvsalud.org)
  • Immunologic mechanisms and heredity (certain human leukocyte antigen subtypes) play a role in etiology. (msdmanuals.com)
  • It is most common among people aged 20 to 50 and is rare in children. (msdmanuals.com)