• Hypercapnia (increased pCO2) sometimes needs to be tolerated in order to achieve these lower tidal volumes. (wikipedia.org)
  • Recent research has shown that moderate hypercapnia is a more scientific and effective treatment. (alliedacademies.org)
  • Influence of moderate hypercapnia on neural activity in monkey by simultaneous intracortical recordings and fMRI at 4.7T . Talk presented at 35th Annual Meeting of the Society for Neuroscience (Neuroscience 2005). (mpg.de)
  • In this study, we used combined intracortical recordings and fMRI in the visual cortex of anesthetized macaque monkeys to show that spontaneous neuronal activity is in fact significantly reduced by moderate hypercapnia. (mpg.de)
  • Symptoms of early hypercapnia (i.e. where PaCO2 is elevated but not extremely so) include flushed skin, full pulse, extrasystoles, muscle twitches, hand flaps, and possibly a raised blood pressure. (wikipedia.org)
  • However, because horses can develop large discrepancies between their PaCO2 and P E CO 2 during anesthesia PE CO 2 should not be relied upon alone to accurately measure the magnitude of hypercapnia, and PaCO2 should be checked using blood gas analysis (see Measurement of carbon dioxide section below). (vetstream.com)
  • The ability of brain cells to regulate intracellular pH (pHi) and several phosphate metabolites was evaluated during 1 h of hypercapnia (inspiratory CO2 fraction of 0.10 and 0.05) in anesthetized rats by 31P high-field (145.6 MHz) nuclear magnetic resonance spectroscopy. (biomedsearch.com)
  • Male Wistar rats (n = 10 per group) were unventilated (CON), mechanically ventilated for 18 hours without (MV) or with hypercapnia (MV + H, Fico 2 = 0.05). (biomedcentral.com)
  • Hypercapnia is often used to accelerate emergence from general anesthesia in the operating room, but little is known about the postoperative effects that may carry over to recovery in the post anesthesia care unit. (usu.edu)
  • Contrary to our expectation, we did non find any potentiation of oxygen induced toxic effects upon the lungs during immersion/hyperoxia/hypercapnia exposures. (sae.org)
  • We determined the influence of brief mild normocapnic hyperoxia, hypoxia, and hyperoxic hypercapnia on human muscle sympathetic nerve activity and R-R intervals, as quantified by both time- and frequency-domain analyses. (unthsc.edu)
  • Average R-R intervals tended to increase during hyperoxia, and decrease during hypoxia and hypercapnia. (unthsc.edu)
  • To investigate the effect of O 2 and CO 2 inhalation (hyperoxia and hypercapnia) on retinal blood vessel calibre and inner retinal function at early stages in the streptozotocin (STZ) model of diabetes. (arvojournals.org)
  • Hypercapnia and hyperoxia produce robust vasodilation and vasoconstriction respectively. (arvojournals.org)
  • Hypercapnia did not affect whole animal oxygen consumption over a period of 4 days. (physiology.org)
  • Role of nitric oxide in regulating cerebrocortical oxygen consumption and blood flow during hypercapnia. (semanticscholar.org)
  • Comparison of hypercapnia-based calibration techniques for measurement of cerebral oxygen metabolism with MRI. (ox.ac.uk)
  • Cerebral metabolic rate of oxygen (CMRO2) can be obtained with magnetic resonance imaging (MRI) by calibrating BOLD using hypercapnia. (mpg.de)
  • Sleep apnea can cause hypercapnia as you are not breathing properly while sleeping, which can result in low oxygen levels and high levels of CO2. (1stclassmed.com)
  • Obesity can also be a cause of hypercapnia, as your body may not get enough oxygen it needs with too much weight pressing on the lungs. (1stclassmed.com)
  • There are a handful of medical conditions that can be the cause of hypercapnia. (1stclassmed.com)
  • We investigated the effect of different levels of hypercapnia on total pulmonary resistance (RL) in 13 subjects ranging from nonsnorers with low RL to snorers with high RL and dynamic narrowing of the upper airway during inspiration. (biomedsearch.com)
  • During NREM sleep, low levels of hypercapnia did not affect RL. (biomedsearch.com)
  • Thus, acute hypercapnia appears to have no adverse inotropic or lusitropic effects on cardiac function, although repolarization abnormalities, reflected by an increase in QT dispersion, and its effects on pulmonary vasoconstriction may have important sequelae in man. (nih.gov)
  • In this pilot study, we hypothesized that hypercapnia would decrease the emergence time from propofol anesthesia by increasing cardiac output and cerebral blood flow. (ekja.org)
  • Inspiratory gases modulated the frequency distribution of muscle sympathetic nerve activity strikingly: hypoxia increased sympathetic power at respiratory frequencies and hypercapnia increased sympathetic power at both respiratory and (primarily in one subject) cardiac frequencies. (unthsc.edu)
  • Hypercapnia had no effect on such indicators of stress as plasma catecholamine or cortisol levels, plasma osmolality or standard metabolic rate. (biologists.org)
  • Constant hypercapnia (60 mm Hg) and lowpH (pH = 6.5) both significantly increased the duration of the SDA response by 22% and 29%, respectively.Hypercapnia had no effect on standard metabolic rate,while constant or oscillating hypercapnia significantly lowered the maximum metabolic rate compared to controls, causing a significant reduction of the aerobic scope during constant hypercapnia. (dtu.dk)
  • Cerebral metabolic rate in hypercapnia: controversy continues. (semanticscholar.org)
  • IMSEAR at SEARO: Metabolic changes in coma and pre-coma states due to hypoxia and hypercapnia. (who.int)
  • We hypothesised that nocturnal NIV would improve QoL, functional and physiological outcomes in subjects with stable CF with impaired nocturnal gas exchange and daytime hypercapnia. (bmj.com)
  • Kawata N, Terada J, Tatsumi K (2016) Persistent daytime hypercapnia predicts poor prognosis in OSAS undergoing CPAP therapy. (springer.com)
  • When hypercapnia occurs, in general, it can result from excess CO2 production or reduced CO2 exhalation from the lungs. (verywellhealth.com)
  • Normoxic hypercapnia and isocapnic hypoxia were induced through a rebreathing method. (elsevier.com)