HyoscyamineButylbromideAlkaloidsSulfateScopolamine or hyoscineAlkaloidMorphineMuscarinic acetylchoAnticholinergicsAntispasmodicsHydrobromideAnticholinergic syndromeNightshadeMethylTherapeutic1795-1867Closely relatedRacemateDrugsDosesDerivativesReducesReceptorsStructuralEffectsProducesCompoundFormTabletsCommonlyBodySolutionRoleAction
Hyoscyamine6
- In herbal medicine the leaves of this plant that contains numerous alkaloids with anticholinergic and antimuscarinic properties are used: l-hyoscyamine and atropine, scopolamine or hyoscine and, all of them potentially high toxic. (e-lactancia.org)
- The plant contains high levels of the alkaloids atropine, hyoscine and hyoscyamine, which inhibit the movement of smooth muscles in the intestines and the secretion of saliva. (farmersweekly.co.za)
- Hyoscyamine is the 3(S)-endo isomer of atropine. (lookformedical.com)
- Only the 1: 1 mixture of ( R ) - and ( S ) -hyoscyamine is called atropine (see Cahn-Ingold-Prelog convention for naming). (zxc.wiki)
- Datura is deliriant because of three main active principles such as hyoscine (scopolamine), hyoscyamine, and atropine. (forensicmcq.com)
- Hyoscyamine should not be confused with hyoscine, an older alternate name for the related nightshade-derived anticholinergic scopolamine . (curecrowd.com)
Butylbromide6
- Each 1 mL contains 20 mg of hyoscine butylbromide. (pharmachoice.com)
- Hyoscine butylbromide is effective in treating cramp abdominal pain. (pharmaxlifesciences.com)
- Hyoscine butylbromide is effective in reducing the duration of the first stage of labour, and it is not associated with any obvious adverse outcomes in mother or neonate. (pharmaxlifesciences.com)
- Each tablet contains hyoscine butylbromide 10 mg. (janusinfo.se)
- There are limited data from the use of hyoscine butylbromide in pregnant women. (janusinfo.se)
- There is insufficient information on the excretion of hyoscine butylbromide and its metabolites in human milk. (janusinfo.se)
Alkaloids3
- Henbane belongs in the Solanaceae family and is highly poisonous containing the alkaloids hyoscamine, hyoscine and atropine, which are responsible for the traditional image of a witch riding a broom. (pagosasun.com)
- Atropine and Hyosine are natural alkaloids which differ quantitatively, main differences being in the action on CNS. (howmed.net)
- It is the levorotary isomer of atropine (third of the three major nightshade alkaloids) and thus sometimes known as levo-atropine. (curecrowd.com)
Sulfate2
- Atropine sulfate is now rarely used for premedication but still has an emergency role in the treatment of vagotonic side effects and is also used to treat acute arrhythmias after myocardial infarction. (formularywkccgmtw.co.uk)
- Atropine sulfate, a very vicinity of nodules from dr. (visitavalladolid.com)
Scopolamine or hyoscine1
- This alkaloid is called scopolamine or hyoscine. (medprep.info)
Alkaloid1
- in the factory isolation of the alkaloid from plants, it is traditionally obtained its inactive racemate - atropine in the form of a salt - Atropini sulfas. (medprep.info)
Morphine2
- In the 1850s, atropine was used as antispasmodic in asthma treatment and as morphine antidote for its mydriatic effect. (wikipedia.org)
- This product has been tested for the prohibited substances caffeine, theophylline, theobromine, hyoscine, hordenine, morphine and atropine and does not contravene FEI rules or the Rules of Racing. (colliespetfood.co.uk)
Muscarinic acetylcho1
- Antimuscarinic agents (also known as muscarinic antagonists), including atropine and hyoscine, block acetylcholine at the muscarinic acetylcholine receptors. (wikipedia.org)
Anticholinergics1
- The anticholinergic effect of drugs such as tri- and tetracyclic antidepressants, antihistamines, quinidine, amantadine, antipsychotics (e.g. butyrophenones, phenothiazines), disopyramide and other anticholinergics (e.g. tiotropium, ipratropium, atropine-like compounds) may be intensified by Buscopan. (janusinfo.se)
Antispasmodics1
- Hyoscine belongs to the group of medications called antispasmodics . (pharmachoice.com)
Hydrobromide1
- Hyoscine hydrobromide reduces secretions and also provides a degree of amnesia, sedation and anti-emesis. (formularywkccgmtw.co.uk)
Anticholinergic syndrome1
- In some patients, especially the elderly, hyoscine may cause the central anticholinergic syndrome. (formularywkccgmtw.co.uk)
Nightshade1
Methyl2
- These are known as inverse agonists and include atropine, M1 selective drugs, Pirenzepine, methyl derivatives of Scopolamine (Hyosine) and trihexphenydle. (howmed.net)
- However, the peripherally acting derivative atropine methyl nitrate (2-10 mg/kg) also attenuated all naloxone-induced withdrawal symptoms except jumping, which was not significantly modified. (lml.com.ly)
Therapeutic1
- An anticholine drug with the therapeutic effect as atropin. (pharmaxlifesciences.com)
1795-18671
- The mydriatic effect was studied by the German chemist Friedlieb Ferdinand Runge (1795-1867), in which the active ingredient, atropine, was first discovered by Vaquelin in 1809 and was first isolated by Heinrich F. G. Mein in 1813. (wikipedia.org)
Closely related1
- The closely related drugs atropine and scopolamine and other members of the anticholinergic drug group like cyclobenzaprine , trihexyphenidyl , and orphenadrine are also used for this purpose. (curecrowd.com)
Racemate1
Drugs1
- Differences observed between atropine and hyoscine with regard to their modifying effects on withdrawal symptoms may be explained on the basis that the drugs may be acting on the different subpopulations of the muscarinic receptor or through non-cholinergic systems. (lml.com.ly)
Doses2
- Atropine was used in cardiopulmonary resuscitation in asystole and pulseless electrical activity (PEA) , doses of 0.5 to a maximum of 3 mg were administered intravenously. (zxc.wiki)
- Withdrawal jumping was potentiated by low and attenuated by high doses of hyoscine. (lml.com.ly)
Derivatives2
- Atropine derivatives. (lookformedical.com)
- Analogs and derivatives of atropine. (lookformedical.com)
Reduces1
- Hyoscine reduces spasms by relaxing smooth muscles within the stomach, intestines, bladder and urethra. (pharmachoice.com)
Receptors1
- Atropine is a competitive antagonist of acetyl choline and other muscarinic agonists on muscarinic receptors, it selectively reduce s or abolishes the muscarinic effects of acetyl choline. (howmed.net)
Structural1
Effects1
- Bezold and Bloebaum showed that atropine blocked the effects of vagal stimulation on the heart in 1867. (wikipedia.org)
Produces1
- When given intravenously it produces less tachycardia than atropine. (formularywkccgmtw.co.uk)
Compound1
- This compound group is defined by the SMILES string 'C(=O)(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)O'. For more information on SMILES, see https://en.wikipedia.org/wiki/Simplified_molecular-input_line-entry_system . (pharosproject.net)
Form2
Tablets1
- The usual dose of hyoscine tablets is 1 or 2 10 mg tablets per day. (pharmachoice.com)
Commonly2
- Hyoscine butyl bromide (HBB) is the most commonly used anti-spasmodic agent in patients undergoing colonoscopy. (gastrores.org)
- Isopto Atropine ( atropine ophthalmic ) is a member of the mydriatics drug class and is commonly used for Pupillary Dilation, Refraction - Assessment, and Uveitis. (drugs.com)
Body1
- Withdrawal body weight loss was dose-dependently attenuated but 'wet dog' shakes, burrowing and hypothermia were markedly potentiated by hyoscine. (lml.com.ly)
Solution1
Role1
- Atropine has limited role therapeutically. (howmed.net)
Action2
- The action of atropine and thioscyamine is antispasmodic, dilating the pupil, relaxing smooth muscles, analgesic, limiting the secretion of sweat glands, relieving the symptoms of motion sickness, and stimulating the central nervous system. (medprep.info)
- otherwise, its action is similar to that of atropine. (medprep.info)