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  • Patients
  • Find Clinical Trials for Hydroxyurea - Check for trials from NCI's list of cancer clinical trials now accepting patients. (cancer.gov)
  • Researchers from the University of Pittsburgh, Duke University, and Dulman, Germany, have reported that the combination of Gleevec (imatinib mesylate) plus hydroxyurea provides benefit for approximately one-half of patients with recurrent glioblastoma multiforme. (fdanews.com)
  • The drug hydroxyurea is used to inhibit the abnormally high level of bone marrow cell proliferation in patients with MPDs. (clinicaltrials.gov)
  • Hydroxyurea has been available for almost fifty years, and has been used to treat patients with MPDs, sickle cell anemia, and congenital heart disease for very prolonged periods of time, up to twenty or more years in individual patients. (clinicaltrials.gov)
  • In the current protocol, we hypothesize that treating patients with PAH with hydroxyurea will decrease the level of circulating immature bone marrow cells and interrupt the abnormal narrowing and occlusion of lung arteries. (clinicaltrials.gov)
  • Hydroxyurea was administered in a clinical trial to fourteen patients with documented disseminated malignant melanoma. (aacrjournals.org)
  • The response of three patients receiving radiotherapy to metastatic brain lesions in combination with hydroxyurea was encouraging enough to warrant a further evaluation of this type of combination therapy. (aacrjournals.org)
  • Data from randomized, controlled clinical trials involving more than 500 patients [6- indicate that hydroxyurea is safe and augments the suppression of HIV replication when used in combination with didanosine (ddI) or ddI/stavudine as initial therapy in patients without extensive antiretroviral experience. (lww.com)
  • Four randomized clinical trials [6- evaluated the effects of hydroxyurea-based antiretroviral regimens in HIV patients at various stages of infection, except during primary HIV infection (PHI). (lww.com)
  • Treatments with therapeutic phlebotomy and hydroxyurea are associated with improved overall survival and decreased risk of thrombosis in older patients with polycythemia vera, according to a recent retrospective cohort study published in Blood Advances. (ajmc.com)
  • Determine the partial and complete response rates in patients with unresectable benign meningioma treated with hydroxyurea. (knowcancer.com)
  • OUTLINE: Patients receive oral hydroxyurea twice daily for 2 years in the absence of disease progression or unacceptable toxicity. (knowcancer.com)
  • used hydroxyurea , a chemotherapeutic agent which induces Hb F production, at a dose of 10 mg/kg, in their patients assuming that since pathophysiology of Hb SD-Punjab is similar to Hb SS, increasing the level of Hb F might decrease the vaso- occlusive events. (thefreedictionary.com)
  • dose
  • After the last dose of hydroxyurea, a man must use birth control for much longer than a woman. (adventisthealthcare.com)
  • Depending on the dose and length of time you have been on hydroxyurea, you may have a reduced response to the skin test. (drugs.com)
  • The recommended dose of hydroxyurea varies according to the specific condition being treated, the response to therapy, the other medications used, whether radiation is being used at the same time, the stage of condition, and the body weight of the recipient. (medbroadcast.com)
  • genetic
  • The GDN earlier reported that more than 40 per cent of sufferers being cared for at the Genetic Blood Disease Centre in SMC are now taking hydroxyurea that was first made widely available in Bahrain last year. (thefreedictionary.com)
  • replication
  • However, the response of BS cells to replication stress induced by hydroxyurea (HU), which strongly slows the progression of replication forks, remains unclear due to publication of conflicting results. (hindawi.com)