• a study of collagen metabolism in cell cultures by fluorometric determination of proline and hydroxyproline. (liverpool.ac.uk)
  • Associated relative increases in the hydroxyproline contents of the (peri)anastomotic colonic segments suggest that an altered collagen metabolism might contribute to this enhancement of the anastomotic repair. (gazi.edu.tr)
  • The aim of the study was to evaluate the efficacy of 2% Cynara scolymus L. extracts in reverse disturbances of collagen metabolism and inflammation in D-galactose induced skin aging model in rats. (scirp.org)
  • Local prolonged treatment with artichoke extracts improved collagen metabolism and attenuated the progression of inflammation in D-galactose induced skin aging model. (scirp.org)
  • This collagen (type III) is gradually replaced by the adult-type collagen (type I). It has been reported that thiamine deficiency has a detrimental effect on collagen metabolism [ 191. (coek.info)
  • Oxalate is involved in various metabolic and homeostatic mechanisms in fungi and bacteria and may play an important role in various aspects of animal metabolism, including mitochondrial activity regulation, thyroid function, gluconeogenesis, and glycolysis. (medscape.com)
  • Metabolism, or the metabolic rate, is defined as the series of chemical reactions in a living organism that create and break down energy necessary for life. (scalarlight.com)
  • BP antagonized metabolic disruption of sphingolipid and glycosaminoglycan metabolism by RSV+Cd, consistent with BP effect on inflammatory markers. (bvsalud.org)
  • In the realm of metabolism, L-Proline may be involved in several metabolic pathways. (codeage.com)
  • Inborn errors of metabolism form a large group of genetic diseases involving defects in genes coding for enzymes, receptors, cofactors etc. in metabolic pathways [ 1 ]. (alliedacademies.org)
  • Inborn errors of metabolism are now often referred to as congenital metabolic diseases or inherited metabolic disorders. (alliedacademies.org)
  • Vitamin C also helps with the metabolism of tyrosine, folic acid, and tryptophan. (naturatomica.com)
  • Urinary compounds, particularly those indicative of bone metabolism and protein turnover -- such as calcium, sodium, potassium, 3-methylhistidine, creatinine, corticosterone, histidine, n-telopeptide, hydroxyproline, pyridinoline, and deoxypyridinoline -- are one of the most valuable sources of data for studying musculoskeletal changes over time in response to altered stimuli, including loading environment. (nasa.gov)
  • Amino acid metabolism has extremely extensive effects in cancer cells, including, but not limited to, (1) establishing amino acid pools as building blocks, especially the production of non-essential amino acids … An overview of the metabolism of the sulfur amino acids is depicted in Fig. The outline of glycine metabolism is depicted in Fig. Oxidation via TCA cycle to produce energy (about 10-15% of body needs). (slimwithlynne.com)
  • Wellbeing Korean Collagen with complete amino acid profile - 18 amino acids including glycine, proline & hydroxyproline ensures complete absorption, making it more potent and efficient. (medcrest.in)
  • Glycine is known to boost metabolism and increase energy levels. (medcrest.in)
  • This enzyme participates in glutamate metabolism and arginine and proline metabolism. (wikipedia.org)
  • The stereoisomer (S)-1-pyrroline-5-carboxylate is an intermediate in glutamate metabolism, arginine degradation, and proline biosynthesis and degradation. (hmdb.ca)
  • Signs and symptoms may include bone pain and/or deformity, neurologic disorders, elevated cardiac output and other vascular disorders, and increased serum alkaline phosphatase and/or urinary hydroxyproline levels. (nih.gov)
  • The serum level of hydroxyproline excretion correlates well with its urinary level. (medscape.com)
  • [ 1 ] However, urinary hydroxyproline better discriminates (x 100) between normal and metastatic disease of the bone. (medscape.com)
  • The ratio of hydroxyproline/creatinine in a fresh specimen of early morning urine, considered the total urinary hydroxyproline, is the best index of collagen breakdown in metastatic bone disease. (medscape.com)
  • Although serum hydroxyproline and urinary hydroxyproline measurements are strongly correlated, urinary hydroxyproline measurement in 24-hour or spot urine is easier to collect. (medscape.com)
  • Klein L. Urinary Hydroxyproline during Late Pregnancy and Postpartum Involution. (medscape.com)
  • Chronically high levels of pyrroline-5-carboxylate are associated with at least five inborn errors of metabolism, including hyperprolinemia type I, hyperprolinemia type II, iminoglycinuria, prolinemia type II, and pyruvate carboxylase deficiency. (hmdb.ca)
  • Spectrum of common and rare small molecule inborn errors of metabolism diagnosed in a tertiary care centre. (alliedacademies.org)
  • Hyperhydroxyprolinemia is a benign condition caused by a defect in 4-hydroxyproline dehydrogenase. (medscape.com)
  • Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase. (wakehealth.edu)
  • In addition, oxalate is created from endogenous sources in the liver as part of glycolate metabolism. (medscape.com)
  • We recently showed that eRSV re-programs metabolism and potentiates Cd toxicity in the lung, and our transcriptome-metabolome-wide study showed strong associations between S-palmitoyl transferase expression and Cd-stimulated lung inflammation and fibrosis signaling. (bvsalud.org)
  • Limited information is available on the mechanism by which eRSV re-programs metabolism and potentiates Cd toxicity in the lung. (bvsalud.org)
  • Collagen protein is critical to a healthy metabolism. (medcrest.in)
  • Urea is the end product of protein metabolism (amino acid metabolism). (slimwithlynne.com)
  • Protein metabolism is more appropriately learnt as metabolism of amino acids. (slimwithlynne.com)
  • It also protects the immune system and helps in protein metabolism . (amaliebeauty.com)
  • Maturation defects in both collagen and mineral ( 45 Ca) metabolism were documented as early as 2 wk after the induction of uremia, when total bone calcium, inorganic phosphate, and hydroxyproline content were unchanged. (jci.org)
  • This compound, also known as EHDP, regulates bone metabolism. (nih.gov)
  • Paget's disease of bone (osteitis deformans) is an idiopathic, progressive disease characterized by abnormal and accelerated bone metabolism in one or more bones. (nih.gov)
  • Valproic acid influenced the levels of amino acids and related metabolites involved in the metabolism of serine, methionine, and leucine. (elsevierpure.com)
  • The vitamin that is a coenzyme in amino acid and nucleic acid metabolism is. (slimwithlynne.com)
  • Disorders that affect the metabolism of amino acids include phenylketonuria, tyrosinemia, homocystinuria, non-ketotic … Essential and nonessential amino acids are degraded to products that can be metabolized for energy. (slimwithlynne.com)
  • Spot urine testing is measurement of choice in screening for bony involvement by malignancy because collagen intake does not influence hydroxyproline/creatinine. (medscape.com)
  • High-fat, low-carbohydrate (CHO) diets increase whole-body rates of fat oxidation and down-regulate CHO metabolism. (edu.au)
  • In addition, lung hydroxyproline content was greater in the cristobalite-exposed animals. (nih.gov)
  • This study shows that Cd exposure following eRSV has a significant impact on subsequent inflammatory response and lung metabolism, which is mediated by Pr-S-Pal, and warrants future research for a therapeutic target. (bvsalud.org)
  • Influence of artichoke extracts restored skin relative weight and led to an increase of solubility in neutral salt and acid, and decreased pepsin solubility collagen fraction, restored the hexosamine/collagen (hydroxyproline) ratio and decreased the activity of nuclear transcription factor (NF-kB). (scirp.org)
  • The liver is the major site of amino acid metabolism in the body and the major site of urea synthesis. (slimwithlynne.com)
  • If not for oxalate's high affinity for calcium and the low solubility of calcium oxalate, oxalate and oxalate metabolism would be of little interest. (medscape.com)
  • [ 9 ] Moreover, hydroxyproline level measurements may permit illness monitoring and assessment of treatment response in such settings. (medscape.com)
  • However, the content of hydroxyproline HPro was 4 to 5 times higher. (ncsu.edu)
  • To determine the effect of thiamine (vitamin B,) on collagen production during wound healing, hydroxyproline content (HP), lysyl oxidase activity (LO), and pepsin-solubilized collagen components were examined in dermis, wound fluid, and artificially induced granulation tissue from surgically wounded rats. (coek.info)
  • The term "non-essential" can be misleading since all amino acids are essential for proper metabolism and certain non-essential amino acids, such as glutamine, become very essential. (criticalbench.com)
  • 67.20, an outline of glutamate and glutamine metabolism is given. (slimwithlynne.com)
  • a technique of derivatization of proline (pro) and 4-hydroxyproline (hyp) by 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole permitted the measurement of pro and hyp radioactivities, concentrations, and specific activities in the main fractions separated from cultures of fibroblast cells (extracellular collagen and non-collagen proteins, intracellular free pro and hyp, pro- and hyp-containing peptides, procollagen, and non-collagen proteins). (liverpool.ac.uk)
  • Amino acids play central roles both as building blocks of proteins and as intermediates in human metabolism. (insideu.ca)
  • Specific differences in metabolism have not been characterized in small dogs as compared to larger dogs. (hindawi.com)
  • Screening infants for increased levels of amino acids can help detect problems with metabolism. (medlineplus.gov)
  • Two isomeric forms of hydroxyproline have been identified in collagenTrans-4-hydroxy-L-proline is found in type I and type III collagen, whereas higher amounts of trans-3-hydroxy-L-proline are found in type IV collagen. (medscape.com)
  • If you have found yourself on this page, you, or someone you know, may be feeling a metabolism imbalance leading toward a desire for sleep, food or depression and you are seeking to restore the balance. (scalarlight.com)
  • It is different for everyone.While the process sounds simple, metabolism, and how it functions in each body, is complex. (scalarlight.com)
  • When your metabolism is working properly for your body type and sex, it should be a background system that your body does not notice. (scalarlight.com)
  • If you are finding that you feel very tired, very hormonal and very hungry, to name a few signs, your metabolism may not be working properly for your body. (scalarlight.com)