• Inhibition of Human Dhodh by 4-Hydroxycoumarins, Fenamic Acids, and N-(Alkylcarbonyl)Anthranilic Acids Identified by Structure-Guided Fragment Selection. (expasy.org)
  • The rodenticide chemicals are sometimes incorrectly referred to as "coumadins" rather than 4-hydroxycoumarins (Coumadin is a brandname for warfarin). (wikipedia.org)
  • Warfarin-induced skin necrosis or, anticoagulant-induced skin necrosis is a condition in which skin and subcutaneous tissue necrosis occurs due to acquired protein C deficiency following treatment with anti-vitamin K anticoagulants (4-hydroxycoumarins, such as warfarin). (capsulehealth.one)
  • 4-Hydroxycoumarins are a class of vitamin K antagonist (VKA) anticoagulant drug molecules derived from coumarin by adding a hydroxy group at the 4 position to obtain 4-hydroxycoumarin, then adding a large aromatic substituent at the 3-position (the ring-carbon between the hydroxyl and the carbonyl). (wikipedia.org)
  • The identification of dicoumarol in 1940 is the precursor of the drug class known as 4-hydroxycoumarins. (wikipedia.org)
  • Furthermore, by the Fold-Change analysis carried out on each phenolic sub-class, Naviglio extractor resulted to recover less common compounds such as chalcones, curcuminoids, hydroxycoumarins, and stilbenes, when compared with samples extracted with Ultra-turrax. (unipg.it)
  • X. Observations on the acetylation of 4-hydroxycoumarin and synthesis of 3-(alpha-aminophenylacetyl)-4-hydroxycoumarins]. (nih.gov)
  • 4-Hydroxycoumarins are a class of vitamin K antagonist (VKA) anticoagulant drug molecules derived from coumarin by adding a hydroxy group at the 4 position to obtain 4-hydroxycoumarin, then adding a large aromatic substituent at the 3-position (the ring-carbon between the hydroxyl and the carbonyl). (wikipedia.org)
  • danish mice (mus musculus domesticus) genetically resistant to the anticoagulant action of two 4-hydroxycoumarins, warfarin and bromadiolone, were examined to determine their mechanism of resistance. (liverpool.ac.uk)
  • Ox idative stress indices and histopathological effects of the nonsteroidal antiinflammatory drug napr ox en in adult zebrafish (Danio rerio). (nel.edu)
  • The aim of this study was to investigate the effects of the nonsteroidal antiinflammatory drug napr ox en on adult zebrafish (Danio rerio). (nel.edu)