- Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. (joplink.net)
- May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. (joplink.net)
- Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. (joplink.net)
- It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides. (lookformedical.com)
- By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS. (lookformedical.com)
- It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. (lookformedical.com)
- [17] Exposure to ultraviolet (UV) radiation can cause direct photooxidation and decompose peroxides and carbonyl molecules. (wikipedia.org)
- The tissue concentration of malondialdehyde was measured to evaluate lipid peroxidation. (asahq.org)
- The beneficial action of propofol is probably correlated with reduction of the hydrogen peroxide-induced lipid peroxidation. (asahq.org)
- [2,3] These reactive oxygen species cause lipid peroxidation of the cell membrane and intracellular Calcium 2 + overload, which are responsible for mechanical and metabolic damage. (asahq.org)
- [5,6] We have demonstrated that treatment with H 2 O 2 produces mechanical dysfunction and metabolic changes, including lipid peroxidation in the isolated perfused heart. (asahq.org)
- Where lipid peroxidation was induced by carbon tetrachloride, curcumin significantly decreased the level of lipid peroxidation. (curcuminhealth.info)
- Ferroptosis, a type of non-apoptotic programmed cell death, is characterized by iron-dependent lipid peroxidation caused by lipoxygenases (e.g. (nature.com)
- In addition, selenium serves as a cofactor of glutathione peroxidase 4 (Gpx4) that inhibits lipid peroxidation, resulting in the attenuation of ferroptosis 17 . (nature.com)
- Thus, it is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. (nih.gov)
- Studies have found that magnesium is critical to the system that can scavenge free radicals and prevent lipid peroxidation, which is a process that damages cell membranes and leads to cell death (1). (dremekblair.com)
- May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. (nih.gov)
- Trace element iodine is an essential component of the thyroid hormones triiodothyronine (T3) and thyroxine (T4), which promote basal metabolism, lipid metabolism, and protein synthesis. (nature.com)
- Hydrogen peroxide (600 microM) significantly increased the left ventricular end-diastolic pressure, decreased the left ventricular developed pressure (i.e., it produced mechanical dysfunction), and decreased tissue concentrations of adenosine triphosphate and creatine phosphate (i.e., metabolic damage). (asahq.org)
- These mechanical and metabolic alterations induced by hydrogen peroxide were significantly attenuated by propofol (25 microM or 50 microM), while the increase in malondialdehyde was completely suppressed by propofol. (asahq.org)
- The current study demonstrates that in the isolated heart, propofol attenuates both mechanical and metabolic changes induced by exogenously applied hydrogen peroxide. (asahq.org)