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Hydrogen PeroxideHydroxylationHydrogenPeroxidesHydrogen BondingCatalaseOxidantsHydrogen SulfideMixed Function OxygenasesOxidation-ReductionCytochrome P-450 Enzyme SystemPeroxidasesLipid PeroxidesMicrosomes, LiverOxidative StressHydroxyl RadicalReactive Oxygen SpeciesProcollagen-Proline DioxygenaseFree RadicalsKineticsSuperoxide DismutaseGlucose OxidaseOxygenAmitroleSteroid HydroxylasesHydroxidesSuperoxidesCatalysisTooth BleachingPeroxiredoxinsAntioxidantsAryl Hydrocarbon HydroxylasesBenzoyl PeroxideAcatalasiaFree Radical ScavengersBiotransformationHorseradish PeroxidaseSteroid 16-alpha-HydroxylaseMolecular Sequence DataGlutathioneHypochlorous AcidSubstrate SpecificitySpectrophotometryChromatography, High Pressure LiquidDebrisoquinAscorbic AcidIronCholestanetriol 26-MonooxygenaseMolecular StructureTooth Bleaching AgentsModels, MolecularMephenytoinAmino Acid SequenceHydrogen-Ion ConcentrationLactoperoxidaseNADPH-Ferrihemoprotein ReductaseGlutathione PeroxidaseElectron Spin Resonance SpectroscopyCytochrome P-450 CYP3ANADPMass SpectrometryPeroxidaseDealkylationModels, ChemicalOxidoreductases, N-DemethylatingOxygenasesOxidoreductasesCells, Culturedtert-ButylhydroperoxideParaquatStereoisomerismMicrosomesXanthine OxidaseHydroxylysineEscherichia coliHydrogen CyanideRecombinant ProteinsDose-Response Relationship, DrugBacterial ProteinsBenzene DerivativesEnzyme InhibitorsFerrous CompoundsLipid PeroxidationProlineCopperMutationSulfhydryl Compounds2,2'-DipyridylMitochondriaHydroxybenzoatesNADTime FactorsMagnetic Resonance SpectroscopySpectrophotometry, UltravioletDeferoxaminePhenolsBenzopyrene HydroxylaseGas Chromatography-Mass SpectrometryCell LineCholestanes
PhenolOxidationOxidantOxidativeBenzeneDemethylationReactionCysteineAsymmetricAmino acidMicrobialCollagenDegradationOxygenSuperoxideSelectiveMineralizationReactionsProteinsGeometrySpeciesPreparationWaterSelectiveEpoxidationCatalyticDecompositionHydroxylChemistryH2O2CytochromeProlineDIOXIDEAlcoholsResiduesOrganicSyntheticHypoxiaEtherRadicalsBondsCompoundSubstratesBiologicalProductionComplexPresenceAgentSolutionDegreeActivityPatternAdds
Phenol4
  • A second route involves hydroxylation of phenol. (camlinfs.com)
  • Catechol is produced by hydroxylation of phenol with hydrogen peroxide in presence of Titanium Silicalite. (cfseuropespa.com)
  • The work presented in this thesis is mainly centered on the synthesis and characterization of some encapsulated transition metal complexes and the catalytic activity of the synthesized complexes in certain organic reactions.thesis deals with the catalytic activity of ruthenium-exchanged zeolite and the zeolite encapsulated complexes of SSC, SOD, SPD, AA, ABA, DMG, PCO, PCP, CPO and CPP in the hydroxylation of phenol using hydrogen peroxide. (cusat.ac.in)
  • 1989). In the first pathway involving ring hydroxylation, opening of the epoxide ring is followed by aromatization resulting in formation of phenol. (cdc.gov)
Oxidation6
  • Using bis(trimethylsilyl) peroxide as the oxidant and simply exchanging dichloromethane, the classical solvent for Baeyer-Villiger oxidation, for the ionic liquid bmimNTf 2 , results in increased product yields. (organic-chemistry.org)
  • One oxidant, hydrogen peroxide, functions as a messenger that can activate cell proliferation through oxidation of cysteine residues in signaling proteins, producing sulfenic acid (i.e. (rdworldonline.com)
  • The catalytic activities for hydrogen peroxide decomposition and oxidation of benzyl alcohol and ethylbenzene of zeolite complexes are reported. (cusat.ac.in)
  • Two isostructural trinuclear coordination polymers (CPs) have been synthesized, characterized and successfully applied as robust heterogeneous catalysts for the oxidation of arylboronic acids into phenols with aqueous hydrogen peroxide (H2O2). (magnusgroup.org)
  • b) They transfer hydrogen from one substrate to another by oxidation-reduction reac-tion not involving a respiratory chain (shown in Fig. 12.4. (biologydiscussion.com)
  • E 0 = 2.8 V, vs. normal hydrogen electrode) which may promote the oxidation of a variety of organic contaminants. (scielo.br)
Oxidant1
Oxidative2
  • The greatly increased extensibility of hydrogen peroxide prepared zein doughs and their improved water-holding are not due to oxidative cross-linking. (edu.au)
  • The attenuation of metal/peroxide oxidative chemistry, as well as lipid peroxidation, appears to be the major chemical mechanisms by which NO may limit oxidative injury to mammalian cells. (researchgate.net)
Benzene2
  • The formation of octahedral vanadium oxide samples possess much removable mobile ligands in the catalytic center that could be easily substituted by hydrogen peroxide and yielded the active peroxo intermediate for further hydroxylation of benzene. (tmu.edu.tw)
  • The tetrahedral coordination of vanadium oxide catalysts showed less mobile ligands in the catalytic medium and yielded lower activity toward the hydroxylation of benzene. (tmu.edu.tw)
Demethylation1
Reaction4
  • In a 2009 study, Carroll found that sulfenic acid served as an early warning biomarker of the reaction between hydrogen peroxide and cysteine. (rdworldonline.com)
  • Peptidylglycine α-hydroxylating monooxygenase (PHM) performs the first step of the amidation reaction-the hydroxylation of peptidylglycine substrates at the Cα position of the terminal glycine. (uconn.edu)
  • The hydroxylation reaction is copper- and O 2 -dependent and requires 2 equiv of exogenous reductant. (uconn.edu)
  • a) Enzymes that catalyse the removal of hy-drogen from a substrate but use only oxy-gen as a hydrogen acceptor to form water as a reaction product (with the exception of uricase and monoamine oxidase which form H 2 O 2 ). (biologydiscussion.com)
Cysteine2
  • The new technique focuses on the process of cysteine S-hydroxylation, which plays a role in a number of events related to physiology in both health and disease, including the regulation of signaling proteins in various disease states. (rdworldonline.com)
  • OH can modify proteins by reacting with tyrosine, tryptophan, cysteine, and methionine residues, promoting hydroxylation and nitration in peptides and proteins, impairing their normal function [ 7 ] . (encyclopedia.pub)
Asymmetric1
  • In this 1.98-Å-resolution structure (hydro)peroxide binds solely to Cu M in a slightly asymmetric side-on mode. (uconn.edu)
Amino acid1
Microbial2
Collagen2
Degradation1
  • Considering that one of the first steps in the degradation of aromatic compounds is the benzenic ring hydroxylation due to electrophilic addition of hydroxyl radical, the generation of di and trihydroxylated intermediates may occur and contribute to the reduction of Fe III species. (scielo.br)
Oxygen3
  • a) They catalyse the removal of hydrogen from a substrate and use either oxygen or artificial substances such a methylene blue as hydrogen acceptor. (biologydiscussion.com)
  • Their isotope-labeling experiments show that the hydroxylation of the peroxy radical (≡SiOO？) is the predominant pathway for H 2 O2 generation, followed by the decomposition of H 2 O 2 into O 2 and H 2 O, while only a small portion of oxygen in ROS derives from water. (cas.cn)
  • A mineral based origin of Earth's initial hydrogen peroxide and molecular oxygen. (cas.cn)
Superoxide1
Selective1
  • These probes, which are highly selective for sulfenic acid, allow the S-hydroxylation process to be monitored at the exact site of the modification. (rdworldonline.com)
Mineralization1
  • Furthermore, the presence of organic carbon and higher salt content in SWW and RE led to lower mineralization per dose of hydrogen peroxide compared to DW and SW. (unboundmedicine.com)
Reactions1
Proteins3
  • Chronic disease states such as cancer can involve the modification of signaling proteins through S-hydroxylation, but other housekeeping proteins may also be targets," she said. (rdworldonline.com)
  • Key to distinguishing which of these proteins may be involved in pathogenesis is the ability to measure the amount of S-hydroxylation at specific sites within a protein. (rdworldonline.com)
  • It should allow researchers to identify proteins with altered S-hydroxylation profiles whose function may lend insight into events in disease progression and have utility as potential markers for disease detection. (rdworldonline.com)
Geometry1
  • The geometry of the observed side-on coordinated peroxide ligand in L 3 Cu M (II)O 2 2− is in good agreement with the results of a hybrid quantum mechanical-molecular mechanical optimization of this species. (uconn.edu)
Species1
  • The O-O interatomic distance of the copper-bound ligand is 1.5 Å, characteristic of peroxide/hydroperoxide species, and the Cu-O distances are 2.0 and 2.1 Å. (uconn.edu)
Preparation1
  • Hydrogen peroxide and peroxidase increased zein dough extensibility compared to preparation with water. (edu.au)
Water2
  • Confocal laser scanning microscopy revealed that in zein-starch doughs prepared with hydrogen peroxide a thin continuous zein matrix was formed around the starch granules, whereas doughs prepared with water exhibited clumps of granules. (edu.au)
  • Her research interests include the advanced materials processing of ideal electrode materials for electrochemical energy storage system applications such as supercapacitor, water splitting process, direct methanol fuel cells, and hydrogen generation. (rsc.org)
Selective5
  • The invention refers to on integrated process for selective oxidation of organic compounds, in liquid phase, which comprises a first step for direct synthesis of a non acidic hydrogen peroxide solution and a second step for oxidation an organic substrate with the reaction mixture of the first step. (justia.com)
  • However, past attempts to develop selective chemical oxidation processes based on hydrogen peroxide have encountered significant difficulties. (justia.com)
  • Accordingly, such conventionally produced hydrogen peroxide is generally too expensive for commercial use as an oxidizing agent for selective chemical oxidation processes. (justia.com)
  • The grain size of the titanium-silicon molecular sieve is less than 1 micrometer, and the titanium-silicon molecular sieve has high activity for selective oxidization reactions using hydrogen peroxide as an oxidant, such as epoxidation of olefins, hydroxylation of phenol, ammoxidation of cyclohexanone and the like. (patsnap.com)
  • 10. Selective carbon-hydrogen bond hydroxylation using an engineered cytochrome P450 peroxygenase. (nih.gov)
Epoxidation3
  • Wang Chuan, Yamamoto Hisashi: Tungsten-Catalyzed Asymmetric Epoxidation of Allylic and Homoallylic Alcohols with Hydrogen Peroxide. (iupac.org)
  • Srour Hassan, Le Maux Paul, Chevance Soizic, Simonneaux Gérard: Metal-catalyzed asymmetric sulfoxidation, epoxidation and hydroxylation by hydrogen peroxide. (iupac.org)
  • C157225 CBDD Terminology C157215 Epoxidation Epoxidation The conversion of a carbon-carbon double bond and oxygen, peroxide or peroxyacid into an a cyclic ether with a three-atom ring (epoxide or oxirane). (nih.gov)
Catalytic4
  • First, the electrochemical characteristics of Fenton's reagent (Fe( III ), Fe( II ) and hydrogen peroxide ), including its catalytic (EC′) behaviour were investigated. (rsc.org)
  • Oxidized compounds are produced in a continuous integrated process in liquid phase, which comprises: Step I, synthesis of non acidic hydrogen peroxide solutions by direct reaction between hydrogen and oxygen by catalytic reaction utilizing a noble metal catalyst. (justia.com)
  • The catalytic activities for hydrogen peroxide decomposition and oxidation of benzyl alcohol and ethylbenzene of zeolite complexes are reported. (cusat.ac.in)
  • The work presented in this thesis is mainly centered on the synthesis and characterization of some encapsulated transition metal complexes and the catalytic activity of the synthesized complexes in certain organic reactions.thesis deals with the catalytic activity of ruthenium-exchanged zeolite and the zeolite encapsulated complexes of SSC, SOD, SPD, AA, ABA, DMG, PCO, PCP, CPO and CPP in the hydroxylation of phenol using hydrogen peroxide. (cusat.ac.in)
Decomposition2
Hydroxyl2
  • The hydroxyl group is incorporated into one fragment of the compound and the hydrogen atom in the other. (nih.gov)
  • C157225 CBDD Terminology C157205 Hydroxylation Hydroxylation The process that introduces a hydroxyl group (-OH) into an organic acceptor molecule. (nih.gov)
Chemistry1
H2O23
Cytochrome3
  • The principal hydroxylation agent in nature is cytochrome P-450 , hundreds of variations of which are known. (wikipedia.org)
  • 9. Enabling Peroxygenase Activity in Cytochrome P450 Monooxygenases by Engineering Hydrogen Peroxide Tunnels. (nih.gov)
  • This laboratory has recently reported that, in a reconstituted enzyme system containing alcohol-induced isozyme 3a of liver microsomal cytochrome P-450, the sum of acetaldehyde generated by the monooxygenation of ethanol and of hydrogen peroxide produced by the NADPH oxidase activity is inadequate to account for the O 2 and NADPH consumed. (elsevierpure.com)
Proline3
  • [9] Proline hydroxylation is also a vital component of hypoxia response via hypoxia inducible factors . (wikipedia.org)
  • Deprivation of ascorbate leads to deficiencies in proline hydroxylation, which leads to less stable collagen, which can manifest itself as the disease scurvy . (wikipedia.org)
  • and (iv) by changes to the fine structure of collagens (e.g. degree of hydroxylation of proline and lysine), glycoproteins (variations of the carbohydrate structure), and proteoglycans (changes of the degree of sulfation of the glycosaminoglycan side chains) combined with certain splice variants of ECM molecules [ 27 ] (Figure 1). (medscape.com)
DIOXIDE2
Alcohols1
  • A second method for the production of hydrogen peroxide comprises the use of secondary alcohols such as isopropanol and methylbenzylalcohol (U.S. Pat. (justia.com)
Residues2
Organic4
  • Step II, this hydrogen peroxide solution is directly mixed with an organic substrate, a suitable catalyst and optionally a solvent. (justia.com)
  • Instead of using organic peroxides, hydrogen peroxide is a known desirable oxidizing agent. (justia.com)
  • also in the production of organic/inorganic peroxy compound like perasetic acid, sodium perborate, sodium percarbonate and calcium peroxide. (dinox.com)
  • US chemists have cracked one of the toughest challenges in organic synthesis: how to attack a complex molecule's unreactive carbon-hydrogen bonds, without resorting to wasteful synthetic aids like protecting and directing groups. (chemistryworld.com)
Synthetic1
  • Singh Rohit, Vince Robert: 2-Azabicyclo[2.2.1]hept-5-en-3-one: Chemical Profile of a Versatile Synthetic Building Block and its Impact on the Development of Therapeutics. (iupac.org)
Hypoxia3
  • These interventions maintained hydroxylation of HIF-1α protein and prevented stabilization of HIF-1α protein during hypoxia. (rupress.org)
  • Antioxidants maintained hydroxylation of HIF-1α protein and prevented stabilization of HIF-1α protein during hypoxia. (rupress.org)
  • In hypoxia, FIH-1 hydroxylation of Asn803 within the C-terminal transactivation domain does not occur and HIF-1α forms a fully active transcriptional complex. (biomedcentral.com)
Ether1
  • Hydrogen Peroxide is soluble in alcohol or ether. (fdocuments.in)
Radicals1
Bonds3
  • 5. Regiodivergent and Enantioselective Hydroxylation of C-H bonds by Synergistic Use of Protein Engineering and Exogenous Dual-Functional Small Molecules. (nih.gov)
  • Christina White and Mark Chen from the University of Illinois say their iron catalyst - which with hydrogen peroxide selectively and predictably oxidises C-H bonds into more reactive C-OH groups - will fundamentally alter the way complex molecules such as drugs are made in the laboratory. (chemistryworld.com)
  • Yet White and Chen's electrophilic iron catalyst, with hydrogen peroxide, selectively oxidised lone C-H bonds from complex molecules with ease. (chemistryworld.com)
Compound1
  • Hydrogen peroxide is a naturally occurring compound found in nature (oceans, lakes, rivers, rain and snow) and in all life forms. (fdocuments.in)
Substrates1
  • When the 4-electron oxidase activity is taken into account, measurements of NADPH oxidation and O 2 consumption are in accord with the amounts of products formed in the presence of various P-450 isozymes, either in the absence or presence of typical substrates, including those which undergo hydroxylation, N- or O-demethylation, or oxidation of hydroxymethyl to aldehyde groups. (elsevierpure.com)
Biological1
  • The biological response to implanted biomaterials strongly depends on their surface properties, such as roughness, chemical composition, charge, wettability and hydroxylation degree. (frontiersin.org)
Production1
  • Conventional hydrogen peroxide production utilizes the anthraquinone process, wherein the anthraquinone is first hydrogenated to anthrahydroquinone and then autoxidized to release hydrogen peroxide and the anthraquinone for recycle. (justia.com)
Complex1
  • Surface properties of biomaterials (e.g., roughness, chemical composition, charge, wettability, and hydroxylation degree) are key features to understand and control the complex interface phenomena that happens upon contact with physiological fluids. (frontiersin.org)
Presence1
Agent1
Solution1
  • Hydrogen peroxide is generated at low concentrations in the solution, and very large flows of anthraquinone and anthrahydroquinone must be handled in order to produce the desired hydrogen peroxide product. (justia.com)
Degree1
Activity1
  • His Sulfamethoxazole study combines topics from a wide range of disciplines, such as Antibacterial activity, Chromatography and Hydrogen peroxide. (research.com)
Pattern1
Adds1