Hydrogels of chitosan. Medical search. Frequent questions

Adding MMP20 to amelogenin-chitosan hydrogel improves biomimetic enamel repair. (iadr.org)

Preparation and enhanced mechanical properties of hybrid hydrogels comprising ultralong hydroxyapatite nanowires and sodium alginate. (nature.com)
PEG-penetrated chitosan-alginate co-polysaccharide-based partially and fully cross-linked hydrogels as ECM mimic for tissue engineering applications. (docksci.com)
In the current study, novel polyethylene glycol interpenetrated cross-linked hydrogel scaffold based on a co-polysaccharide (PIAC) synthesized from two marine heteropolysaccharides, alginate and chitosan, was designed. (docksci.com)
The physiochemical evaluations of both the hydrogels revealed the presence of alginate fraction and extensive -OH groups on the surface, sufficient water content and water holding capacity. (docksci.com)
Effect of Chitosan on alginate-based macroporous hydrogels for the capture of glioblastoma cancer cells. (polymtl.ca)
An alginate-based macroporous hydrogel matrix to trap cancer cells. (polymtl.ca)
Characterization and Mathematical Modeling of Alginate/Chitosan-Based Nanoparticles Releasing the Chemokine CXCL12 to Attract Glioblastoma Cells. (polymtl.ca)

Synthesis of interpenetrating polymer network (IPN) of chitosan-gelatin (Cs-Ge) (as a primary network) and N-isopropylacrylamide (NIPAAm) monomer (as the secondary network) was carried out with different ratio. (techno-press.org)
Methods of synthesis of hydrogels … a review. (nature.com)
A porous hydrogel nanocomposite with semi-interpenetrating network of chitosan (CS) and graphene oxide (GO) was fabricated, which acted as a nanoreactor for in-situ synthesis of silver nanoparticles (AgNPs) and their subsequent immobilization. (thapar.edu)
1] E.-R. Kenawy, E. A. Kamoun, M. S. M. Eldin, and M. A. El-Meligy, "Physically crosslinked poly(vinyl alcohol)- hydroxyethyl starch blend hydrogel membranes: Synthesis and characterization for biomedical applications," Arabian Journal of Chemistry , vol. 7, pp. 372-380, 2014. (edu.vn)
Controlling the distribution of nanoparticles in hydrogels via interfacial synthesis. (polymtl.ca)

Then chitosan (CS) and cyclodextrin grafted glutamic acid (CD-g-Glu) were used to prepare chitosan/cyclodextrin derivatives thermosensitive hydrogel (CS/CD-g-Glu) to improve the properties of chitosan-based thermosensitive hydrogels. (korea.ac.kr)

Moreover, the osmolality of the medium in contact with the hydrogel was in the range of 310-330 mmol kg(-1). (ox.ac.uk)
MTT assay on hydrogel extracts and direct contact assay showed the nontoxic effects of fibroblast cells upon contact with the hydrogel. (docksci.com)

The POSTECH researchers claim that this chitosan (a biodegradable polymer) hydrogel film can quickly swell and contract like a super sponge: it can absorb water around it at nearly 1,000 weight percentage of its dried weight. (allaboutcircuits.com)
This highly-absorbant quality comes from the hydrogen bonding between water molecules and the chitosan polymer. (allaboutcircuits.com)

abstract = "A novel preparation method for modified chitosan membranes was developed. (elsevierpure.com)

Overcoming the impermeability of the mucin layer and the urothelium is a large focus of many intravesical drug formulations, and is key to an efficacious intravesical treatment The main ways researchers are currently overcoming the problems in intravesical drug delivery are through developing formulations using mucoadhesives, nanoparticles, liposomes, polymeric hydrogel, expandable delivery devices, and electromotive drug administration. (wikipedia.org)
In the present study, a biogenically-derived polymeric nanocomposite of nano-silver/chitosan/graphene oxide hydrogel was synthesized in order to evaluate its catalytic performance to degrade methylene blue (MB) as a model dye under sunlight illumination. (thapar.edu)
The hydrogel nanocomposites were characterized using electron microscopy which indicated a stable formation of nanocomposite with immobilized AgNPs onto polymeric networks. (thapar.edu)

However, current overviews in recent publications involving chitin and chitosan research advances appear lacking. (mdpi.com)
With the opening of this Special Issue, Advances in Marine Chitin and Chitosan in Marine Drugs , we plan to produce a strong, very exciting issue that will encompass breakthroughs in high value, scientific and industrial chitin and chitosan research. (mdpi.com)

Here, Biodegradable composite hydrogels comprised of carboxymethyl chitosan (CMCS) and clindamycin (CDM)- loaded mesoporous silica nanoparticles (MCM-41), possessing dual antibacterial activity and osteogenic potency, were developed. (mahidol.ac.th)
More specifically synthetic polylactic/glycolic acid nanoparticles (11 12 and thermo-reversible triblock copolymer poloxamer 407 hydrogels Lu AE58054 (13-15) have been utilized for the controlled release of encapsulated molecules including dexamethasone across the RWM with encouraging results. (ecolowood.com)

This review focuses on the current use of injectable in situ chitosan hydrogels in cancer treatment. (edu.au)
Preparation, fabrication and biocompatibility of novel injectable temperature-sensitive chitosan/glycerophosphate/collagen hydrogels. (ox.ac.uk)
This paper introduces a novel type of injectable temperature-sensitive chitosan/glycerophosphate/collagen (C/GP/Co) hydrogel that possesses great biocompatibility for the culture of adipose tissue-derived stem cells. (ox.ac.uk)
This study demonstrated a chitosan (CS)/polyglutamate (PG) polyelectrolyte complex (PEC) hydrogel combined with spherical hydroxyapatite (HAp) particles as an injectable dermal filler for soft-tissue augmentation. (tmu.edu.tw)

Composite gels made from a cross-linked mixture of chitosan and BSA exhibited the swelling behavior of BSA combined with the mechanical properties of chitosan and were therefore considered most suitable for use in a gastric environment. (uea.ac.uk)
The hydrogel is prepared conveniently with hydroxyethyl acrylate, cross-linker, gelatin and photoinitiator, and can be printed into certain 3D patterns with the direct ink write (DIW) 3D printer designed and developed by the research group.Design/methodology/approachIn this paper, the authors designed a composite sensitization initiation system that is suitable for hydrogels. (deepdyve.com)
With the DIW 3D printer, pre-gel hydrogel solution can be printed into objects with certain dimension.Originality/valueIn this work, a composite sensitization initiation system was designed, and fast curing hydrogels with adjustable mechanical properties had been prepared conveniently, which has high equilibrium water content and 3D printability with the DIW 3D printer. (deepdyve.com)

As a step prior to clinical trials, this study aimed to examine the efficacy of CS-AMEL hydrogel in biomimetic repair of human enamel with erosive or caries-like lesions in pH-cycling systems. (sciedupress.com)

The gelation temperature of the FA-G/C/GP hydrogel was 32.17 °C. NP cells submitted to oxidative stress promoted by H 2 O 2 , and post-treated with FA-G/C/GP exhibited down-regulation of MMP-3 and up-regulation aggrecan and type II collagen in mRNA level. (tau.ac.il)
The C/GP/Co hydrogel is prepared by mixing 2.2% (v/v) chitosan with 50% (w/w) β-glycerophosphate at different proportions and afterwards adding 2 mg/ml of collagen. (ox.ac.uk)
Mechanical stimulation led to a significant increase in chondrogenic gene expression, while histological analysis detected sulphated glycosaminoglycans and collagen II only in loaded specimens, confirming MC hydrogel suitability to support load induced MSCs chondrogenesis. (nature.com)

The inner structure of the hydrogel presented a porous spongy structure, as observed by scanning electron microscopy. (ox.ac.uk)
The biological evaluations confirmed the healthy being and 3D growth of fibroblasts on the porous networks of both the hydrogels. (docksci.com)
Development and Characterization of Functional Polylactic Acid/Chitosan Porous Scaffolds for Bone Tissue Engineering. (polymtl.ca)

Herein we report on a detailed study about the gelation kinetics of carboxymethyl chitosan-zinc (CMCh-Zn) supramolecular hydrogel by taking advantage of its intrinsic fluorescence property. (unisa.it)

Hydrogel: preparation, characterization, and applications: a review. (nature.com)
Orthogonal optimisation experiments were designed to obtain optimal process parameters for hydrogel preparation with the cellulose dosage of 0.40 g, initiator dosage of 0.20 g, polymerisation temperature of 70°C, cross-linking agent of 0.25 g, and monomer dosage of 3.0 mL. (techscience.com)

the IPN hydrogels showed a interpenetrated network of NIPAAm/chitosan has layers with more minute stoma and canals compared to interpenetrated network of NIPAAm/gelatin. (techno-press.org)
In the study, we developed the thermosensitive FA-gelatin/chitosan/glycerol phosphate (FA-G/C/GP) hydrogel which was applied as a sustained release system of FA to treat NP cells from the damage caused by oxidative stress. (tau.ac.il)
Similarly natural hydrogels made of gelatin (16-20) hyaluronate. (ecolowood.com)
While adding various content of gelatin and cross-linker, the mechanical properties of hydrogels show from soft and fragile (elastic modulus of 121.18 kPa and work of tension of 218.11 kJ·m−3) to rigid and tough (elastic modulus of 505.15 kPa and work of tension of 969.00 kJ·m−3). (deepdyve.com)

Hypothesis A chitosan-hydrogel-based nanoparticle (nanohydrogel) delivery system can be used to deliver therapeutic biomaterials across the round windows membrane (RWM) into the inner ear in a mouse model. (ecolowood.com)
Close-up view of a metallic nanoparticle hydrogel-mirror etalon under a humid and dry state surrounding. (allaboutcircuits.com)

Unique molecular interactions between graphene derivatives and various small or macromolecules enable the fabrication of various functional hydrogels appropriate for different biomedical applications. (nature.com)
In this mini-review, we highlight the recent progress in GO-incorporated hydrogels for biomedical applications while focusing on their specific uses as mechanically strong materials, electrically conductive scaffolds/electrodes, and high-performance drug delivery vehicles. (nature.com)
Recent developments in tough hydrogels for biomedical applications. (nature.com)
Hydrogels for biomedical applications. (nature.com)
Chai Q, Jiao Y, Yu X. Hydrogels for biomedical applications: their characteristics and the mechanisms behind them. (nature.com)
Biomedical applications of hydrogels: a review of patents and commercial products. (nature.com)

Graphene and graphene derivatives (e.g., graphene oxide (GO)) have been incorporated into hydrogels to improve the properties (e.g., mechanical strength) of conventional hydrogels and/or develop new functions (e.g., electrical conductivity and drug loading/delivery). (nature.com)
Functionalized carbon nanotube and graphene oxide embedded electrically conductive hydrogel synergistically stimulates nerve cell differentiation. (nature.com)

Fan, Jun 2021-06-04 00:00:00 This paper aims to show a series of hydrogels with adjustable mechanical properties, which can be cured quickly with visible light. (deepdyve.com)

Chitosan hydrogel had been widely used in cell culture and tissue engineering, but its long gel time, weak mechanical strength, and weak antibacterial performance limited its application. (korea.ac.kr)
More importantly, the CS/CD-g-Glu hydrogel loaded with BBH showed prefect antibacterial activity against E. coli and S. aureus. (korea.ac.kr)
The antibacterial studies done under liquid culture and solid media indicated that the pure GO-CS hydrogels could not demonstrate any significant antibacterial effect. (thapar.edu)

7] E. A. Kamoun, X. Chen, M. S. M. Eldin, and E.-R. S. Kenawy, "Crosslinked poly(vinyl alcohol) hydrogels for wound dressing applications: A review of remarkably blended polymers," Arabian Journal of Chemistry , vol. 8, pp. 1-14, 2015. (edu.vn)

Therefore, the CS/CD-g-Glu hydrogel has great promising applications in drug delivery, tissue engineering, biotechnological, and biomedical fields. (korea.ac.kr)
Human adipose tissue-derived stem cells (ADSCs) were seeded into the developed C/GP and C/GP/Co hydrogels (The ratios of C/GP and C/GP/Co were 5:1 and 5:1:6, respectively), and the cellular growth was periodically observed under an inverted microscope. (ox.ac.uk)
Chitosan (CS) is a polycationic polysaccharide comprising glucosamine and N- acetylglucosamine and constitutes a potential material for use in cartilage tissue engineering . (bvsalud.org)
In conclusion, CS hydrogels were able to stimulate tissue ingrowth and accelerate the process of cartilage repair in animal studies. (bvsalud.org)
Song F, Li X, Wang Q, Liao L, Zhang C. Nanocomposite hydrogels and their applications in drug delivery and tissue engineering. (nature.com)
The present hydrogel can form an ECM mimic and can form a potent candidate for various tissue engineering applications. (docksci.com)

The properties of cross-linked chitosan hydrogels were explained in terms of its polyelectrolyte behavior, which led to a gradual increase in swelling ratio below the pK value, but whereby its swelling ability was eliminated by the presence of salt that screened the charges. (uea.ac.uk)

Formulation protocols for in situ hydrogel systems, their cytotoxic properties, loading and in vitro release of drugs, their effect on cell growth in vitro and inhibition of tumor growth in vivo using mouse models, and future directions to enhance this technology are discussed. (edu.au)

Matured raw Alphonso mango fruits were simple dip treated/coated and air dried with our newly developed chitosan based formulation (for industry) with additives. (degruyter.com)
The scientific story behind this effective chitosan based coating formulation development has been discussed. (degruyter.com)

Chitosan hydrogel membranes were prepared by immersing an aqueous acetic acid solution of chitosan in KOH solution and modified with 3,3′‐dithiodipropionic acid (DTPA), which has a functional group that causes the thiol ⟷ disulfide transition through a redox reaction. (elsevierpure.com)
6] Z. Abdeen, S. G. Mohammad, and M. S. Mahmoud, "Adsorption of Mn (II) ion on polyvinyl alcohol/chitosan dry blendingfrom aqueous solution," Environmental Nanotechnology, Monitoring &Managemen , vol. 3, pp. 1-9, 2015. (edu.vn)

Permeabilities of KCl, sucrose, and urea through these modified chitosan membranes were investigated. (elsevierpure.com)

This information is also important to study chitosan/derivatives elicitation in molecular level to improve mango flavor as well as in identification of genes responsible for flavor quality. (degruyter.com)

Affinity-controlled capture and release of engineered monoclonal antibodies by macroporous dextran hydrogels using coiled-coil interactions. (polymtl.ca)
Macroporous dextran hydrogels for controlled growth factor capture and delivery using coiled-coil interactions. (polymtl.ca)

Experimental and theoretical investigations of the swelling and mechanical properties of hydrogels formed from chitosan, bovine serum albumin (BSA), and chitosan/BSA mixtures cross-linked with genipin were performed. (uea.ac.uk)

In: Emerging concepts in analysis and applications of hydrogels. (nature.com)
Hydrogels as emerging materials for translational. (nature.com)

Live/dead assay using ethidium bromide/acridine orange cocktail on fibroblast cells grown on the hydrogels after 5 days of initial seeding displayed green nucleus revealing the non-apoptotic cells. (docksci.com)

Montheil T, Echalier C, Martinez J, Subra G, Mehdi A. Inorganic polymerization: an attractive route to biocompatible hybrid hydrogels. (nature.com)

Obviously, CD44 expression on 3A6 and SW620 cells was dynamic and diverse when they were in the aggregated state suspended on chitosan, while Hs68 cells were relatively stable. (degruyter.com)
Furthermore, we discuss how to regulate CD44 expression of 3A6 and SW620 cells by the interactions between cell and cell, cell and chitosan, as well as cell and microenvironment. (degruyter.com)
Finally, the possible mechanism of chitosan to control CD44 expression of cells is proposed, which may lead to the careful use of chitosan for potential clinical applications. (degruyter.com)
The results suggest that the thermosensitive FA-G/C/GP hydrogel can treat NP cells from the damage caused by oxidative stress and may apply in minimally invasive surgery for NP regeneration. (tau.ac.il)
After 7 days of culture, cells within the C/GP/Co hydrogels displayed a typical adherent cell morphology and good proliferation with very high cellular viability. (ox.ac.uk)
It was found that cartilage repair was improved with the treatment of CS hydrogel , especially the one enriched with cells . (bvsalud.org)

Then, cellulose hydrogel was prepared by graft copolymerisation using N, N'-methylenebisacrylamide as the cross-linking agent, sodium persulfate as the initiator, and acrylic acid as the monomer. (techscience.com)

The synthesized hydrogels showed remarkable swelling capacities with swelling ratio of 83.17% and 80.23% for GO-CS and GO-CS-Ag respectively. (thapar.edu)

Amelogenin-chitosan ( CS-AMEL ) hydrogel has shown great potential for the prevention, restoration, and treatment of defective enamel. (sciedupress.com)
After pH cycling and treatment with CS-AMEL hydrogel, a synthetic layer composed of oriented apatite crystals was formed on the eroded enamel surface. (sciedupress.com)

In addition, CS hydrogel produced an upregulation of genes and proteins that act in the cartilage repair process, improving the biomechanical properties of gait . (bvsalud.org)
Fu J, In Het Panhuis M. Hydrogel properties and applications. (nature.com)
Improving hydrogels' toughness by increasing the dissipative properties of their network. (nature.com)

Later a more advanced model, developed in 1D geometry and solved numerically, is used to describe and predict experimental results, proving its reliability and the correct description of all the phenomena involved in the gelation process of CMCh-Zn hydrogel. (unisa.it)

These analyses have shown that the C/GP/Co hydrogels are structurally feasible for cell culture, while their biocompatibility was further examined. (ox.ac.uk)

Experiment conducted under sunlight (natural source) with GO-CS hydrogel showed a 99.7% degradation of MB (initial concentration, 40 ppm) within 5 hrs. (thapar.edu)
The CS/PG PEC hydrogel with oppositely charged ionic cross-linking, a high gel content, and low degradation rate was introduced as a carrier to achieve high shape and volume stability. (tmu.edu.tw)

We used chitosan to establish a suspension culture model to develop multicellular spheroids to mimic a three-dimension (3D) in vivo environment. (degruyter.com)
The search was done by the descriptors of the Medical Subject Headings (MeSH) defined below " Chitosan ," " hydrogel ," " cartilage repair," and "in vivo. (bvsalud.org)
The lack of any hydrogel-derived immunoreaction was demonstrated in vivo by mice subcutaneous implantation. (nature.com)

PIAC-P hydrogels were superior to certain aspects due to the availability of free functional groups than PIAC-F where most of these groups were utilized for cross-linking. (docksci.com)

Chen C-C, Wang J-M, Huang Y-R, Yu Y-H, Wu T-M, Ding S-J. Synergistic Effect of Thermoresponsive and Photocuring Methacrylated Chitosan-Based Hybrid Hydrogels for Medical Applications. (mdpi.com)
Bahram M, Mohseni N, Moghtader M. An introduction to hydrogels and some recent applications. (nature.com)
The Global Market for Hydrogels 2024-2034 provides a comprehensive analysis of the global hydrogel landscape, technologies, companies, and applications across major industry verticals. (researchandmarkets.com)
This study serves as a strategic guide for companies and investors looking to capitalize on the major growth opportunities for hydrogels across a diverse set of high-potential markets and applications. (researchandmarkets.com)

The CS/CD-g-Glu hydrogel had temperature sensitivity and stable three-dimensional network structure. (korea.ac.kr)

The results clearly demonstrate that the CS-AMEL hydrogel is effective at the restoration of erosive and carious lesions under pH-cycling conditions. (sciedupress.com)

The resonant frequency depended on the thickness and the refractive index of the hydrogel film. (allaboutcircuits.com)
By programming the imposed cathodic input signals, chitosan hydrogels with varying layer number and thickness can be fabricated. (rsc.org)

Anatomy5

Chemicals and Drugs34

Analytical, Diagnostic and Therapeutic Techniques and Equipment17

Phenomena and Processes14

Disciplines and Occupations3

Technology, Industry, Agriculture18

Amelogenin-chitosan hydrogel1

Alginate7

Synthesis5

Thermosensitive hydrogel1

Contact with the hydrogel2

Polymer2

Abstract1

Polymeric3

Chitin and Chitosan2

Nanoparticles2

Injectable4

Composite3

Biomimetic1

Collagen3

Porous3

Carboxymethyl1

Preparation2

Gelatin4

Nanoparticle2

Biomedical applications6

Graphene oxide2

20211

Antibacterial3

Polymers1

Tissue6

Polyelectrolyte1

Vitro1

Formulation2

Aqueous2

Membranes1

Derivatives1

Dextran2

Mechanical1

Emerging2

Fibroblast1

Biocompatible1

Cells6

Sodium1

Ratio1

Enamel2

Properties3

Gelation1

Biocompatibility1

Degradation2

Vivo3

Functional1

Applications4

Stable1

Demonstrate1

Thickness2