ZoloftSelective serotoninTabletsParoxetineSSRIEfficacy of sertralineAntidepressantsFluoxetineDepressionSSRIsCapsulePediatric patientsAntidepressant actionAmitriptyline2020StrengthChemical NameObsessive-compulsiNortriptylinePanic DisorderPost TraumatiPhase IV clinical studyTreatmentActive ingredientsPTSDInhibitsSignificantlyDosageSideOccursInteractionsPatientsPregnancyPfizer
Zoloft16
- Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. (wikipedia.org)
- The Zoloft generic is sertraline. (canadapharmacy.com)
- The active ingredient in Zoloft is sertraline. (canadapharmacy.com)
- In re Zoloft (Sertraline Hydrochloride) Prod. (dechert.com)
- But millions of people around the globe have fought off depression and led more fulfilling lives thanks in part to his discovery-sertraline hydrochloride, better known as Zoloft . (reed.edu)
- I tested every one of those isomers-one turned out to be a selective serotonin reuptake inhibitor [SSRI], and that compound became sertraline hydrochloride, which developed into Zoloft. (reed.edu)
- Does CBD Interact With Sertraline (Zoloft)? (dailycbd.com)
- CBD may act as a competitive inhibitor for the same enzymes that metabolize sertraline (Zoloft). (dailycbd.com)
- Because of CBD's effects on the enzymes that metabolize sertraline (Zoloft), the latter drug is likely to be more potent than usual. (dailycbd.com)
- If you want to mix CBD with sertraline (Zoloft), talk to your doctor first . (dailycbd.com)
- Because CBD lacks extensive studies on its effectiveness, it cannot be considered a good alternative to sertraline (Zoloft). (dailycbd.com)
- What Is Sertraline (Zoloft)? (dailycbd.com)
- Sertraline hydrochloride was invented and marketed by Pfizer with the brand name Zoloft. (dailycbd.com)
- What Does Sertraline (Zoloft) Do? (dailycbd.com)
- Sertraline (Zoloft) is an SSRI and inhibits the reuptake of serotonin in the brain. (dailycbd.com)
- Like most other medications, sertraline (Zoloft) also has side effects. (dailycbd.com)
Selective serotonin3
- Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. (medchemexpress.com)
- Sertraline hydrochloride is a selective serotonin reuptake inhibitor (SSRI) for oral administration. (prescriptiondrugs.com)
- Sertraline is classified as an SSRI (selective serotonin reuptake inhibitor). (dailycbd.com)
Tablets5
- These highlights do not include all the information needed to use SERTRALINE HYDROCHLORIDE TABLETS safely and effectively. (nih.gov)
- See full prescribing information for SERTRALINE HYDROCHLORIDE TABLETS. (nih.gov)
- Protriptyline hydrochloride tablets are indicated for the treatment of symptoms of mental depression in patients who are under close medical supervision. (nih.gov)
- Protriptyline hydrochloride tablets are contraindicated in patients who have shown prior hypersensitivity to it. (nih.gov)
- Providing you the best range of amitriptyline hydrochloride tablets ip 10, escitalopram oxalate tablets, eszopiclone 1,2,,3 mg tablets, tranylcypromine tablets 10 mg, desvenlafaxine extended release tablets and low dose naltrexone tablets with effective & timely delivery. (bombaymedicos.com)
Paroxetine4
- Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. (rawsgearpharma.com)
- Sertraline appears to work better in melancholic depression than fluoxetine, paroxetine, and mianserin and is similar to the tricyclic antidepressants such as amitriptyline and clomipramine. (wikipedia.org)
- Second, the first-line treatments ("fluoxetine", "paroxetine", "sertraline", "venlafaxine", "trauma-focused cognitive behavioral therapy", "cognitive processing therapy", "EMDR", "prolonged exposure", "stress management" and "narrative exposure therapy" ) recommended in the current guidelines [6-9] were combined with OR. (ugeskriftet.dk)
- We included randomised clinical trials evaluating the outcome of a trauma-focused psychotherapy, cognitive behavioural therapy (CBT), prolonged exposure therapy (PE), cognitive processing therapy, eye movement desensitisation and reprocessing (EMDR), or narrative exposure therapy or stress management compared with treatment by sertraline, paroxetine, fluoxetine or venlafaxine, or combinations of these, to reduce PTSD symptoms in adults. (ugeskriftet.dk)
SSRI1
- Sertraline used for the treatment of depression in elderly (older than 60) patients is superior to placebo and comparable to another SSRI fluoxetine, and tricyclic antidepressants (TCAs) amitriptyline, nortriptyline and imipramine. (wikipedia.org)
Efficacy of sertraline7
- The efficacy of Sertraline hydrochloride in the treatment of a major depressive episode was established in six to eight week controlled trials of adult outpatients whose diagnoses corresponded most closely to the DSM-III category of major depressive disorder (see Clinical Trials under CLINICAL PHARMACOLOGY ). (medlibrary.org)
- The efficacy of sertraline hydrochloride in maintaining an antidepressant response for up to 44 weeks following 8 weeks of open-label acute treatment (52 weeks total) was demonstrated in a placebo-controlled trial. (medlibrary.org)
- The efficacy of Sertraline hydrochloride was established in 12-week trials with obsessive-compulsive outpatients having diagnoses of obsessive-compulsive disorder as defined according to DSM-III or DSM-III-R criteria (see Clinical Trials under CLINICAL PHARMACOLOGY ). (medlibrary.org)
- The efficacy of Sertraline hydrochloride in maintaining a response, in patients with OCD who responded during a 52-week treatment phase while taking Sertraline hydrochloride and were then observed for relapse during a period of up to 28 weeks, was demonstrated in a placebo-controlled trial (see Clinical Trials under CLINICAL PHARMACOLOGY ). (medlibrary.org)
- The efficacy of Sertraline hydrochloride was established in three 10-12 week trials in adult panic disorder patients whose diagnoses corresponded to the DSM-III-R category of panic disorder (see Clinical Trials under CLINICAL PHARMACOLOGY ). (medlibrary.org)
- The efficacy of sertraline for depression is similar to that of other antidepressants, and the differences are mostly confined to side effects. (wikipedia.org)
- Multiple controlled clinical trials established efficacy of sertraline for the treatment of depression. (wikipedia.org)
Antidepressants8
- Angle Closure Glaucoma: Avoid use of antidepressants, including sertraline hydrochloride, in patients with untreated anatomically narrow angles. (nih.gov)
- Sertraline is better tolerated than the older tricyclic antidepressants. (wikipedia.org)
- Similar to other antidepressants, the use of sertraline for depression may be associated with a mildly elevated rate of suicidal thoughts in people under the age of 25 years old. (wikipedia.org)
- In general, sertraline efficacy is similar to that of other antidepressants. (wikipedia.org)
- For example, a meta-analysis of 12 new-generation antidepressants showed that sertraline and escitalopram are the best in terms of efficacy and acceptability in the acute-phase treatment of adults with depression. (wikipedia.org)
- There are differences between sertraline and some other antidepressants in their efficacy in the treatment of different subtypes of depression and in their adverse effects. (wikipedia.org)
- A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as sertraline during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). (discountcanadadrugs.com)
- You should know that your mental health may change in unexpected ways when you take sertraline or other antidepressants even if you are an adult over 24 years of age. (discountcanadadrugs.com)
Fluoxetine1
- Sertraline may be more efficacious for the treatment of depression in the acute phase (first four weeks) than fluoxetine. (wikipedia.org)
Depression9
- Sertraline (10 mg/kg) is shown to produce the optimal anti-depression effectsin chronic unpredictable mild stress (CUMS)-exposed mice [3] . (medchemexpress.com)
- Sertraline is used for a number of conditions including: major depression, obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder and social anxiety disorder.It has also been used for premature ejaculation and vascular headaches but evidence of the effectiveness in treating those conditions is not robust. (rawsgearpharma.com)
- Continued treatment with sertraline prevents both a relapse of the current depressive episode and future episodes (recurrence of depression). (wikipedia.org)
- In several double-blind studies, sertraline was consistently more effective than placebo for dysthymia, a more chronic variety of depression, and comparable to imipramine in that respect. (wikipedia.org)
- Sertraline also improves the depression of dysthymic patients to a greater degree than psychotherapy. (wikipedia.org)
- For severe depression, sertraline is as good as clomipramine but is better tolerated. (wikipedia.org)
- In the treatment of depression accompanied by OCD, sertraline performs significantly better than desipramine on the measures of both OCD and depression. (wikipedia.org)
- Sertraline is equivalent to imipramine for the treatment of depression with co-morbid panic disorder, but it is better tolerated. (wikipedia.org)
- Sertraline is used to treat depression, obsessive-compulsive disorder (bothersome thoughts that won't go away and the need to perform certain actions over and over), panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks), posttraumatic stress disorder (disturbing psychological symptoms that develop after a frightening experience), and social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life). (discountcanadadrugs.com)
SSRIs3
- The incidence of diarrhea was higher with sertraline-especially when prescribed at higher doses-in comparison to other SSRIs. (rawsgearpharma.com)
- Sertraline shares the common side effects and contraindications of other SSRIs, with high rates of diarrhea, nausea, insomnia, and sexual dysfunction, but it appears not to lead to much weight gain, and its effects on cognitive performance are mild. (wikipedia.org)
- Sertraline belongs to a class of medications known as selective serotonin reuptake inhibitors (SSRIs). (pharmasave.com)
Capsule3
- Pill with imprint T 50 is Blue, Capsule/Oblong and has been identified as Sertraline Hydrochloride 50 mg. (drugs.com)
- Each yellow capsule contains sertraline hydrochloride equivalent to 25 mg of sertraline. (pharmasave.com)
- Each white and yellow capsule contains sertraline hydrochloride equivalent to 50 mg of sertraline. (pharmasave.com)
Pediatric patients1
- Protriptyline hydrochloride is not approved for use in pediatric patients. (nih.gov)
Antidepressant action1
- The antidepressant action of sertraline hydrochloride in hospitalized depressed patients has not been adequately studied. (medlibrary.org)
Amitriptyline2
- Compared with amitriptyline, sertraline offered a greater overall improvement in quality of life of depressed patients. (wikipedia.org)
- The leading psychopharmaceutical drugs prescribed are Citalopram Hydrobromide (14+ Million in 2017) and Amitriptyline Hydrochloride (13+ Million in 2017). (abbeycarefoundation.com)
20201
- In 2016, sertraline was the most commonly prescribed psychotropic medication in the United States and in 2020, it was the twelfth most commonly prescribed medication overall in the United States, with over 38 million prescriptions. (wikipedia.org)
Strength1
- EP 127 Color Yellow Shape Round View details WPI 2775 Metformin Hydrochloride Strength 850 mg Imprint WPI 2775 Color Orange Shape Oval View details Can't find. (borreliosidilyme.it)
Chemical Name1
- Sertraline hydrochloride has the following chemical name: (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride. (prescriptiondrugs.com)
Obsessive-compulsi3
- Sertraline is primarily prescribed for major depressive disorder in adult outpatients as well as obsessive-compulsive disorder, panic disorder, and social anxiety disorder, in both adults and children. (rawsgearpharma.com)
- Sertraline is effective for panic disorder, social anxiety disorder, generalized anxiety disorder (GAD), and obsessive-compulsive disorder (OCD). (wikipedia.org)
- Sertraline has been approved for major depressive disorder (MDD), obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder, and social anxiety disorder (SAD). (wikipedia.org)
Nortriptyline1
- Nortriptyline Hydrochloride ( Safe. (e-lactancia.org)
Panic Disorder1
- Panic Disorder - Sertraline hydrochloride is indicated for the treatment of panic disorder in adults, with or without agoraphobia, as defined in DSM-IV. (medlibrary.org)
Post Traumati1
- citation needed] Although approved for post-traumatic stress disorder (PTSD), sertraline leads to only modest improvement in this condition. (wikipedia.org)
Phase IV clinical study2
- The phase IV clinical study analyzes what interactions people who take Sertraline hydrochloride and Vytorin have. (ehealthme.com)
- The phase IV clinical study analyzes which people take Sertraline hydrochloride and have Excessive or unwanted hair in women. (ehealthme.com)
Treatment4
- If it occurs, discontinue sertraline hydrochloride and initiate supportive treatment. (nih.gov)
- Major Depressive Disorder - Sertraline hydrochloride is indicated for the treatment of major depressive disorder in adults. (medlibrary.org)
- Sertraline also alleviates the symptoms of premenstrual dysphoric disorder (PMDD) and can be used in sub-therapeutic doses or intermittently (luteal phase dosing) for its treatment. (wikipedia.org)
- Your healthcare provider will want to see you often while you are taking sertraline, especially at the beginning of your treatment. (discountcanadadrugs.com)
Active ingredients2
- Sertraline hydrochloride has active ingredients of sertraline hydrochloride . (ehealthme.com)
- It is based on sertraline hydrochloride (the active ingredients of Sertraline hydrochloride) and Sertraline hydrochloride (the brand name). (ehealthme.com)
PTSD2
- Patients with PTSD who received exposure or sertraline therapies evidenced improvements that were sustained for 24 months. (psychiatrist.com)
- 10 Reportedly, these therapies are more effective than sertraline for patients with PTSD. (psychiatrist.com)
Inhibits3
- Sertraline (1 μM, 12 hours) inhibits high mobility group box 1 (HMGB1)- or tumor necrosis factor-α (TNF-α)-induced microglial activation and inflammatory mediator production in microglia [3] . (medchemexpress.com)
- Sertraline (1 μM) inhibits the HMGB1/toll-like receptor 4 (TLR4)- and TNF-α/TNF receptor 1 (TNFR1)-mediated nuclear factor-kappa B (NF-κB) activation in HMGB1- or TNF-α-stimulated microglia [3] . (medchemexpress.com)
- Sertraline binds to the serotonin transporter (SERT) and inhibits the CNS neuronal retaking of serotonin (5HT). (dailycbd.com)
Significantly2
- The number of neurons in the vehicle group is significantly decreased compared with the control group, whereas neuron numbers in the CUMS-exposed mice treated with arctiin and Sertraline hydrochloride (SERT) are apparently recovered. (medchemexpress.com)
- N-Desmethyl sertraline is significantly less active analogue as compared to the methylated compound, Sertraline. (globalchemmall.com)
Dosage1
- Nevertheless, the physician who elects to use Sertraline hydrochloride for extended periods should periodically re-evaluate the long-term usefulness of the drug for the individual patient (see DOSAGE AND ADMINISTRATION ). (medlibrary.org)
Side3
- We study 23,420 people who have side effects when taking Sertraline hydrochloride. (ehealthme.com)
- 23,420 people reported to have side effects when taking Sertraline hydrochloride. (ehealthme.com)
- Because of this, sertraline might remain in the body for longer and could cause some side effects, ranging from simple ones to serious ones, such as serotonin syndrome. (dailycbd.com)
Occurs1
- Sertraline has much lower rates of adverse effects than these TCAs, with the exception of nausea, which occurs more frequently with sertraline. (wikipedia.org)
Interactions3
- Drug interactions are reported among 79 people who take Sertraline hydrochloride and Vytorin. (ehealthme.com)
- 79 people who take Sertraline hydrochloride and Vytorin together, and have interactions are studied. (ehealthme.com)
- Information on risks & possible interactions between CBD & sertraline. (dailycbd.com)
Patients2
- QTc Prolongation: Sertraline hydrochloride should be used with caution in patients with risk factors for QTc prolongation. (nih.gov)
- The usefulness of the drug in patients receiving sertraline hydrochloride for extended periods should be reevaluated periodically (see Clinical Trials under CLINICAL PHARMACOLOGY ). (medlibrary.org)
Pregnancy1
- Sertraline taken during pregnancy is associated with an increase in congenital heart defects in newborns. (wikipedia.org)
Pfizer1
- Sertraline was invented and developed by scientists at Pfizer and approved for medical use in the United States in 1991. (wikipedia.org)