OrganismsChemicals and DrugsHealth Care
Protocatechuate-3,4-DioxygenaseHydrocarbonsHydrocarbons, AromaticReceptors, Aryl HydrocarbonPolycyclic Hydrocarbons, AromaticAmino Acids, AromaticPolycyclic CompoundsTetrachlorodibenzodioxinHydrocarbons, HalogenatedBenzo(a)pyreneCytochrome P-450 CYP1A1Aryl Hydrocarbon Receptor Nuclear TranslocatorPyrenesBiodegradation, EnvironmentalHydrocarbons, ChlorinatedBenz(a)AnthracenesAryl Hydrocarbon HydroxylasesAlkanesPetroleumBenzopyrenesCarbon-Carbon LyasesRhodocyclaceaeAcetate-CoA LigasePetroleum PollutionBetaproteobacteriaPolypodiaceae
PolycyclicCompoundsMetabolismPathwayHeterocyclicMicrobialBacterialAlkeneFattyAminoMeatsGenesProteinHumansIsolateSubstancesPotentialEffectsIncludesEssentialProductionHealthPolycyclicPAHsPetroleum HydrocarbonsDegradation of hydrocarbonsTolueneMetabolitesPseudomonasBenzeneToxicBiosynthesisGene clusterConcentrationsExposureAerobicAlkylFamilyEnvironment
Polycyclic10
  • EI-Sheekh MM, Ghareib MM, EL-Souod GW A (2011) IBiodegradation of Phenolic and Polycyclic Aromatic Compounds by Some Algae and Cyanobacteria. (omicsonline.org)
  • The degradation of polycyclic aromatic hydrocarbons by different algae seems to be related to the molecular structures of the compound and physiological metabolism of the algae. (omicsonline.org)
  • 2006. Microbial dioxygenase gene population shifts during polycyclic aromatic hydrocarbon biodegradation. (nih.gov)
  • Plant-mediated effects on polycyclic aromatic hydrocarbon (PAH) degradation by bacteria in the rhizosphere of the salt marsh grasses, Spartina alterniflora and Phragmites australis. (nih.gov)
  • An example of these would be polycyclic aromatic hydrocarbons (PAHs). (dailyhealthvalley.com)
  • Comamonas testosteroni (C. testosteroni) is able to catabolize a variety of steroids and polycyclic aromatic hydrocarbons. (idexlab.com)
  • Comamonas testosteroni is able to catabolize a variety of steroids and polycyclic aromatic hydrocarbons and might be used in the bioremediation of contaminated environments. (idexlab.com)
  • Within PyOM, the metabolism of specific chemistries differed strongly between unlimited and oxygen-limited conditions - degradations of anhydrosugars, phenols, and polycyclic aromatic hydrocarbons (PAHs) were more favorable under oxygen limitation than other molecules. (copernicus.org)
  • Anaerobic degradation of polycyclic aromatic hydrocarbons and alkanes in petroleum-contaminated marine harbor sediments. (umass.edu)
  • Anaerobic, sulfate-dependent degradation of polycyclic aromatic hydrocarbons in petroleum-contaminated harbor sediment. (umass.edu)
Compounds8
  • There are few examples of algae degrading aromatic compounds [ 5 , 6 ] examined the effects of the chlorophyte alga, Selenstrum capriconutum , on benzo pyrene. (omicsonline.org)
  • The selection of the genes for the anaerobic degradation of aromatic compounds was based on the proteogenomics-based reconstruction of their catabolism in the denitrifying Aromatoleum aromaticum EbN1 [78] and the sulfate-reducing Desulfobacula toluolica Tol2 [15]. (biomedcentral.com)
  • One of the typically unused fractions of biomass is the structural component, referred to as lignin, that makes up 15 to 30% of the material and when depolymerized generates a heterogeneous mixture of toxic aromatic compounds. (wustl.edu)
  • Taken together, this work greatly advances the ability to engineer R. opacus for any desired application, in addition to providing understanding into its catabolism of aromatic compounds. (wustl.edu)
  • They may be grouped further into aliphatic-chain compounds, such as n -hexane, and as aromatic compounds with a 6-carbon ring, such as benzene or xylene. (medscape.com)
  • Rhodococcus opacus PD630 is a promising strain for the biological upgrading of lignin due to its ability to tolerate and utilize lignin-derived aromatic compounds. (biomedcentral.com)
  • Anaerobic degradation of aromatic compounds coupled to Fe(III) reduction by Ferroglobus placidus. (umass.edu)
  • Pyridines and derivatives are compounds containing a pyridine ring, which is a six-member aromatic heterocycle which consists of one nitrogen atom and five carbon atoms. (hmdb.ca)
Metabolism3
  • Metabolism comprises two directions: catabolism and anabolism. (ppt-online.org)
  • d) It is highly significant in the liver and kid-neys of birds which excrete uric acid as the end product of purine metabolism and also of protein and amino acid catabolism. (biologydiscussion.com)
  • For the stage of metabolism, see catabolism . (wikipedia.org)
Pathway1
  • Streptomyces coelicolor gylR, a repressor of the gylCABX operon for the glycerol catabolism pathway. (expasy.org)
Heterocyclic1
  • It is a relatively simple heterocyclic aromatic organic compound that is structurally related to benzene, with one CH group in the six-membered ring replaced by a nitrogen atom. (hmdb.ca)
Microbial2
  • The goal of this dissertation is to greatly expand the genetic toolbox available in R. opacus in order to provide insight into its aromatic catabolism and to promote its use as a microbial chassis for the conversion of biomass-derived products into biofuels or other value-added products. (wustl.edu)
  • The aim of this study was to examine the microbial community in a petroleum contaminated site, and isolate organisms potentially able to degrade hydrocarbons. (springeropen.com)
Bacterial2
  • Through successive enrichment of soil microorganisms from samples of an historic petroleum contaminated site in Wietze, Germany, we isolated a bacterial consortium using diesel fuel hydrocarbons as sole carbon and energy source. (springeropen.com)
  • The analysis of both the metagenome of the consortium and the reconstructed metagenome-assembled genomes show that the most abundant bacterial genus in the consortium, Acidocella , possess many of the genes required for the degradation of diesel fuel aromatic hydrocarbons, which are often the most toxic component. (springeropen.com)
Alkene1
  • Fig.2 A, B). IsoMO is a member of the soluble di-iron monooxygenase (SDIMO) family of proteins and has homology to alkene/aromatic monooxygenases and soluble methane monooxygenase. (jcmurrell.co.uk)
Fatty1
  • The up-regulated members of ABC transport systems, aromatics degradation, and fatty acid degradation indicated a reinforced transfer and utilization of E2. (bvsalud.org)
Amino1
  • Tryptophan contains an α-amino group, an α-carboxylic acid group, and a side chain indole, making it a non-polar aromatic amino acid. (pinnacleclinic.com)
Meats1
  • where the mother and infant without catabolism of lean meats and vegetables, and toxin from the l. (revivemedicalny.com)
Genes1
  • Four additional genes, isoGHIJ, are adjacent the IsoMO structural genes and encode enzymes involved in the subsequent steps in isoprene catabolism. (jcmurrell.co.uk)
Protein1
  • Ensuring protein intake is essential to avoid muscular catabolism, which prevents the development of sarcopenia in the medium and long term. (dailyhealthvalley.com)
Humans1
  • 1994). Because of the long-half life of most of the halogenated aromatic hydrocarbons, animals or humans will be exposed for relatively long periods of time following single exposures. (cdc.gov)
Isolate1
  • Acetate catabolism in the dissimilatory iron-reducing isolate GS-15. (umass.edu)
Substances1
  • Catabolism includes reactions of substances decomposition, which come into the organism with food. (ppt-online.org)
Potential2
  • Lignin is a recalcitrant aromatic polymer that is a potential feedstock for renewable fuel and chemical production. (biomedcentral.com)
  • We successfully isolated and analysed a potential hydrocarbon-degrading consortium. (springeropen.com)
Effects1
  • Alternative sources of energy and chemicals are needed, however, as hydrocarbon reserves continue to deplete and the effects of burning fossils on the planet become better understood. (wustl.edu)
Includes1
  • Outer membrane transport proteins (OMPP1/FadL/TodX) family includes several proteins that are involved in toluene catabolism and degradation of aromatic hydrocarbons. (wikipedia.org)
Essential1
  • It was also indicated that the rich presence of essential oil (oleoresins) determines the aromatic flavoring, coloring and pungent properties of pepper fruits. (projecttopics.com)
Production2
  • Most of the carbon tetrachloride produced is used in the production of chlorofluorocarbons (CFCs) and other chlorinated hydrocarbons. (projecttopics.com)
  • Volatile hydrocarbon production by Ascocoryne sacroides was studied over its growth cycle. (springeropen.com)
Health1
Polycyclic7
  • Nitrated polycyclic aromatic hydrocarbons (nitro-PAHs) enter the environment from natural sources and anthropogenic activities. (nih.gov)
  • The identity of the small molecule/compound represented by the molecular features differing statistically between preterm birth cases and term controls was identified as ranging from those involved with endogenous metabolic pathways (including lipid catabolism, steroids, and steroid-related molecules) to exogenous exposures (including avocadyne, diosgenin, polycyclic aromatic hydrocarbons, acetaminophen metabolites, aspartame, and caffeine). (nih.gov)
  • Oil spills are costly and ecologically damaging as polycyclic aromatic hydrocarbons have been linked to cardiac arrhythmia in marine organisms. (kenyon.edu)
  • 13 Pseudomonas stutzeri's relative abundance was seen as a result of its ability to utilize aromatic hydrocarbons such as xylene, toluene, phenol, as well as polycyclic aromatic hydrocarbons , such as naphthalene . (kenyon.edu)
  • Alkane degradation ability was near ubiquitous among candidate hydrocarbon degraders, whereas just three harbored elaborate gene inventories for the degradation of alkanes and aromatic and polycyclic aromatic hydrocarbons (PAHs). (nature.com)
  • Another important risk factor, in particular with regards to occupational settings, is the chronic exposure to polycyclic aromatic hydrocarbons (PAH) which are formed during incomplete combustion of organic material and thus can be found in coal tar, creosote, bitumen and related working materials. (frontiersin.org)
  • 1. The administration of polycyclic aromatic hydrocarbons (PAHs) causes the biosynthesis of cytochrome P:-450, a molecular species of cytochrome P-450 not normally detectable in appreciable amounts of microsomes from untreated or phenobarbital-treated animals. (nih.gov)
PAHs1
Petroleum Hydrocarbons2
  • Bioremediation is a strategy that uses naturally occurring organisms to break down pollutants, such as petroleum hydrocarbons, into less toxic substances. (kenyon.edu)
  • This is further supported by CONCAWE 2019 (An Evaluation of the Persistence, Bioaccumulation and Toxicityof Petroleum Hydrocarbons) attached to IUCLID section 13. (europa.eu)
Degradation of hydrocarbons1
  • Researchers were able to amplify the genes for the enzymes used in the degradation of hydrocarbons from Pseudomonas stutzeri . (kenyon.edu)
Toluene2
  • Outer membrane transport proteins (OMPP1/FadL/TodX) family includes several proteins that are involved in toluene catabolism and degradation of aromatic hydrocarbons. (wikipedia.org)
  • These enzymes include: benzoate dioxygenase, toluene 1,2-dioxygenase, and catechol 1,2-dioxygenase, which play a role in aromatic hydrocarbon degradation, and methanol dehydrogenase, which is involved in aliphatic hydrocarbon degradation. (kenyon.edu)
Metabolites2
  • In further assessing the type of metabolites formed, it has been demonstrated that for all the major classes of hydrocarbons, the major metabolites are in most cases less toxic, and always less bioaccumulative than the parent molecule. (europa.eu)
  • Consequently, it is concluded that for PBT and risk assessment purposes, the metabolites of hydrocarbons do not require any further assessment. (europa.eu)
Pseudomonas4
  • Species in the bacterial genus Pseudomonas present high potential for hydrocarbon degradation due to their metabolic diversity, their abundance in microbial communities, and their resistance to chemical remediation agents present at contamination sites. (kenyon.edu)
  • 10 Pseudomonas species have been found to dominate hydrocarbon degrading bacterial communities even in the Artic-an environment that entails extreme temperature conditions, limited availability of nutrients such as nitrogen, and low levels of available water. (kenyon.edu)
  • Pseudomonas abundance dropped off after a year, at t = 1y, after prolonged degradation of available hydrocarbons. (kenyon.edu)
  • In a metagenomic analysis of the microbial population in petroleum pipelines, Pseudomonas stutzeri was detected as the most abundant hydrocarbon degrading organism. (kenyon.edu)
Benzene1
  • 2008. The roles of ring-hydroxylating dioxygenases in styrene and benzene catabolism in Rhodococcus sp. (ubc.ca)
Toxic1
  • are capable of utilizing this aromatic compound [ 10 - 15 ], there are a considerable number of studies about the toxic effects of hydroquinone. (hindawi.com)
Biosynthesis1
  • magadii contained three genes en coding putative enzymes from the later on phases from the fol ate biosynthesis pathway. (cgrpreceptor.com)
Gene cluster2
  • Analysis of the complete genome of strain JS3065 indicated that the gene cluster encoding 1-nitronaphthalene catabolism ( nin ) is located on a plasmid. (nih.gov)
  • 2007. A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages. (ubc.ca)
Concentrations2
  • This makes it difficult to assess environmental exposure of petroleum substances from field monitoring studies because measured concentrations of constituents or total hydrocarbons detected in the environment can no longer be directly related to the original petroleum substance. (europa.eu)
  • A further complication is multiple hydrocarbon sources, both man-made and natural, which may contribute to concentrations observed in each environmental compartment (CONCAWE, 1999). (europa.eu)
Exposure1
  • To quantify environmental exposure resulting from multimedia distribution and degradation of hydrocarbon components that comprise a complex petroleum substance the 'Hydrocarbon Block Method', has been proposed by CONCAWE (1996) and EC (2003) and subsequently implemented in REACH (ECHA, 2008). (europa.eu)
Aerobic1
  • Hydrocarbons are degraded (under aerobic conditions) via mono-oxygenases or di-oxygenases, and are subsequently carboxylated and ultimately hydroxylated. (europa.eu)
Alkyl1
  • an aromatic ring (Ar−X), or an alkyl group. (openstax.org)
Family1
  • 2008. Distinct roles for two CYP226 family cytochromes P450 in abietane diterpenoid catabolism by Burkholderia xenovorans LB400. (ubc.ca)
Environment2
  • When a complex petroleum substance is released into the environment, the hydrocarbon constituents distribute to the different environmental compartments according to individual physico-chemical properties (e.g. volatility, water solubility, partition coefficients). (europa.eu)
  • In this approach, individual hydrocarbons with different partitioning and degradation properties are used to simulate petroleum substance fate in the environment. (europa.eu)