Loading...
  • HHUS1B
  • Recently, paralogues of human and mouse HUS1 , deemed HHUS1B and Mhus1B , respectively, have been identified (12) , and the former has been characterized in some detail. (aacrjournals.org)
  • These findings suggested that HHUS1 and HHUS1B have related but not identical functions in cell cycle checkpoint control and perhaps other as of yet undefined cellular processes. (aacrjournals.org)
  • interactions
  • Physical interactions among human checkpoint control proteins HUS1p, RAD1p, and RAD9p, and implications for the regulation of cell cycle progression. (genesilico.pl)
  • somatic cells
  • 1994). Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle. (core.ac.uk)
  • chromosome
  • 2009). A mechanism for chromosome segregation sensing by the NoCut checkpoint. (core.ac.uk)
  • Failure to establish this checkpoint results in catastrophic mitoses, where acentric chromosome fragments are lost and incompletely repaired chromosomes fail to segregate. (genetics.org)