• Jurkat cells are an immortalized line of human T lymphocyte cells that are used to study acute T cell leukemia, T cell signaling, and the expression of various chemokine receptors susceptible to viral entry, particularly HIV. (wikipedia.org)
  • IHC-P: Human tonsil tissue. (abcam.com)
  • 2000 ). The encapsulation of cells has been developed to avoid immune rejection in cell/tissue transplantation. (springer.com)
  • Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 11265-1-AP (CD31 antibody) at dilution of 1:4000 (under 10x lens). (ptglab.com)
  • Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 11265-1-AP (CD31 antibody) at dilution of 1:4000 (under 40x lens). (ptglab.com)
  • Recent findings in our laboratory and those of others, however, have shown that the EBV receptor is also present on T cells. (nih.gov)
  • J.RT3-T3.5 cells have a mutation in the T cell receptor beta chain locus precluding expression of this chain. (wikipedia.org)
  • they do not express surface CD3 or produce the T cell receptor alpha/beta heterodimer. (wikipedia.org)
  • Since they are deficient in the TCR complex, these cells are a useful tool for transfection studies using T cell receptor alpha and beta chain genes and are widely used in labs in which T cell receptor gene transfer technologies are studied. (wikipedia.org)
  • The D1.1 cell line does not express the CD4 molecule, an important co-receptor in the activation pathway of helper T cells. (wikipedia.org)
  • The J.gamma1 subline contains no detectable phospholipase C-gamma1 (PLC-γ1) protein and therefore has profound defects in T cell receptor (TCR) calcium mobilization and activation of nuclear factor of activated T cells (NFAT, an important transcription factor in T cells). (wikipedia.org)
  • Blockade of inhibitory receptor programmed cell death protein 1 (PD-1) in vivo increased mTOR activity in virus-specific CTLs, and its therapeutic effects were abrogated by the mTOR inhibitor rapamycin. (nih.gov)
  • simultaneously bind to major histocompatibility complex published a study of seven patients with severe streptococ- class II molecules and T-cell receptor molecules bearing a cal infections: SPE-A was detected in serum samples from four patients (27). (cdc.gov)
  • In this study, we compared how different signaling pathways determine extracellular nucleotide pools in control Jurkat cells versus Jurkat lines that lack the Fas-associated death domain (FADD) or receptor-interacting protein kinase 1 (RIP1) cell death regulatory proteins. (aspetjournals.org)
  • Stimulation of T cells through the T-cell receptor results in the activation of a series of signaling pathways that leads to the secretion of interleukin (IL)-2 and cell proliferation. (cdc.gov)
  • Since epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors, including gefitinib (GEF) have been reported to induce the apoptosis of several cancer cell lines, in the present study, we examined whether the cytotoxic effects of GEF are further enhanced under amino acid starvation (AAS) culture conditions. (spandidos-publications.com)
  • We assessed cell proliferation, clonogenic survival and delayed luminescence of treatedcells. (unict.it)
  • Protein kinase B (also known as AKT) and the mechanistic target of rapamycin (mTOR) are central regulators of T cell differentiation, proliferation, metabolism, and survival. (nih.gov)
  • Bcl-2 protein blocks apoptosis (programmed cell death), and thereby may contribute to tomorigenesis by prolonging cell survival rather than by accelerating the rate of cell proliferation. (bdbiosciences.com)
  • Jurkat T cells encapsulated with a double layer of PSS-GNR/PAH (PSS-GNR/PAH@Jurkat) showed the highest rate of cell proliferation when compared to 24-h encapsulated cells. (springer.com)
  • Gene expression must be appropriately maintained to regulate development, differentiation, and proliferation of cells. (intechopen.com)
  • In cell coculture assays, ICOVIR-15K-cBiTE-mediated oncolysis resulted in robust T-cell activation, proliferation, and bystander cell-mediated cytotoxicity. (aacrjournals.org)
  • These findings show exogenous 24:6ω-3 can be incorporated into primary human T lymphocytes and Jurkat cells and induces changes in fatty acid composition consistent with its conversion to 22:6ω-3 via a mechanism involving peroxisomal β-oxidation that is regulated independently from the integrity of the upstream PUFA synthesis pathway. (soton.ac.uk)
  • The interaction of FAS/FASL in immature dendritic cells (DCs) induces functional maturation. (biolegend.com)
  • This study compared the effect of incubation with 24:6ω-3 on the fatty acid composition of two related cell types, primary CD3+ T lymphocytes and Jurkat T cell leukemia, which differ in the integrity of the polyunsaturated fatty acid (PUFA) biosynthesis pathway. (soton.ac.uk)
  • Incubation with 24:6ω-3 induced similar increments in the amount of 22:6ω-3 in both cell types and modified the homeoviscous adaptations fatty acid composition induced by activation of T lymphocytes. (soton.ac.uk)
  • To investigate whether carbamate pesticides also induce apoptosis in human T lymphocytes, in the present study Jurkat human T cells were treated in vitro with thiram, maneb, carbaryl or ziram. (researchgate.net)
  • Human T lymphocytes play an important role in the immune system and have been used in immunotherapy (Juan et al. (springer.com)
  • Therefore, cell encapsulation of T lymphocytes might help mitigate this problem and increase the efficiency of immunotherapy in many diseases. (springer.com)
  • Human peripheral blood lymphocytes (PBLs) were from mice infected with a SAg-producing S. pyogenes purified from blood of a healthy donor by using strain (29). (cdc.gov)
  • Despite the existence of a highly immunosuppressive tumor environment, adenovirus-infected cells can nonetheless be efficiently cleared by infiltrating cytotoxic T lymphocytes (CTL) without compromising tumor burden. (aacrjournals.org)
  • Inhibition of cytotoxic effect of FASL on Jurkat cells in the presence of recombinant human FAS. (biolegend.com)
  • The cytotoxic effects in the HL60, Jurkat and THP-1 lineages were mediated via an apoptotic mechanism when treated with crude ethanol extracts from these species. (iomcworld.com)
  • For immunohistochemistry of paraffin-embedded sections, the monoclonal mouse anti-human Bcl-2 (clone Bcl-2/100, Cat. (bdbiosciences.com)
  • Explore our solutions for multiple applications - vaccines, monoclonal antibodies, recombinant proteins, cell or gene therapy. (vwr.com)
  • OriGene offers a range of tools to analyze CD markers including cDNA clones, antibodies, overexpression cell lysates and more. (origene.com)
  • Approx 55kDa band observed in lysates of cell line Jurkat (calculated MW of 55.2kDa according to NP_055121.1). (prosci-inc.com)
  • The JCaM1.6 cell line is deficient in Lck activity due to the deletion of part of the LCK gene (exon 7) from the LCK transcript. (wikipedia.org)
  • Translocation of bcl-2 sequences from chromosome 18 onto the transcriptionally active immunoglobulin locus at chromosome band 14q32 in B-cells deregulates bcl-2 gene expression, resulting in high levels of bcl-2 mRNA. (bdbiosciences.com)
  • Global analysis of gene expression in cells of the immune system II. (cheric.org)
  • Caspase-activated DNase (CAD) or DNA fragmentation factor subunit beta is a protein that in humans is encoded by the DFFB gene. (wikipedia.org)
  • Recent global analyses of gene transcripts revealed that specific transcription factors (TFs) and their networking systems physiologically correspond to the onset of human diseases, including cancer. (intechopen.com)
  • Mutations in the CACNA1S gene change single protein building blocks (amino acids) used to make the CACNA1S protein, which alters the structure and function of calcium channels in skeletal muscle cells. (medlineplus.gov)
  • A synthetic peptide containing amino acids 61-76 of the human Bcl-2 protein was used as immunogen. (bdbiosciences.com)
  • Here, we present a method that allows the measurement of asymmetric organelle partitioning, and we use it to simultaneously measure the partitioning of three kinds of cellular elements, i.e. cytoplasm, membrane, and mitochondria in a proliferating population of human Jurkat T-cells. (biorxiv.org)
  • We found that although cell cytoplasm is divided symmetrically, mitochondria and membrane lipids are asymmetrically distributed between the two daughter cells and present a stable positive correlation with cytoplasm apportioning, which is incompatible with an independent division mechanism. (biorxiv.org)
  • Therefore, our findings show that asymmetric segregation mechanisms can also arise in cancer cell populations, and that, in this case, membrane lipids and mitochondria do not respectively segregate independently from the cytoplasm. (biorxiv.org)
  • The transport of serum amino acids into cells is an active process that is facilitated by plasma membrane-localized amino acid transporters. (spandidos-publications.com)
  • Serum components, like serum amyloid P component (SAP), together with membrane receptors on phagocytes play essential roles in the phagocytosis of apoptotic cells. (biomedcentral.com)
  • Calcium channels made with the CACNA1S subunit are located in the outer membrane of muscle cells, so they can transmit electrical signals from the cell surface to inside the cell. (medlineplus.gov)
  • RYR1 channels are located in the membrane of a structure inside the cell that stores calcium ions. (medlineplus.gov)
  • An IL-2 producing cell line, derived by incubating the cells at 41°C for 48 hours followed by a limiting dilution cloning over macrophages. (sigmaaldrich.com)
  • Interestingly, when encapsulated cells were co-cultured with THP-1 macrophages, co-cultures exhibited TNF-α production enhancement. (springer.com)
  • Human tumor necrosis factor alpha (TNF alpha) is a proinflammatory cytokine expressed mainly by activated monocytes and macrophages. (ancell.com)
  • It is detected in human alveolar macrophages, osteoclasts, spleen and liver. (thermofisher.com)
  • Human peripheral blood monocytes were isolated and cultured for 7 days to obtain monocyte derived macrophages. (biomedcentral.com)
  • Phagocytosis was performed by incubation of macrophages for 30 minutes with EA or LA cells in the presence of human serum (HS) and depicted as phagocytosis index (PI, number of Jurkatt internalized by 100 macrophages). (biomedcentral.com)
  • SAP binds to late apoptotic cells and is involved in the phagocytosis of these cells by human monocyte derived macrophages. (biomedcentral.com)
  • We previously found that carbamate pesticides induced significant apoptosis in human natural killer cells. (researchgate.net)
  • The Jurkat cell line (originally called JM) was established in the mid-1970s from the peripheral blood of a 14-year-old boy with T cell leukemia. (wikipedia.org)
  • Different derivatives of the Jurkat cell line that have been mutated to lack certain genes can now be obtained from cell culture banks. (wikipedia.org)
  • The I 2.1 cell line is functionally defective for FADD and the I 9.2 cell line is functionally defective for caspase-8, both defective molecules being essential to apoptosis or necroptosis of cells. (wikipedia.org)
  • The STR profile of these cell lines match that of its parental cell line - ECACC catalog number 88042803. (sigmaaldrich.com)
  • This product is a panel of eleven (11) genetically modified cell lines targeting MHC Class I HLA molecules in a Jurkat T lymphocyte parental cell line background. (sigmaaldrich.com)
  • The full HLA panel consists of a Beta-2 microglobulin (β2M) knockout cell line and an additional ten (10) monoallelic HLA expression cell lines. (sigmaaldrich.com)
  • CompoZr ® Zinc Finger Nuclease (ZFN) technology was used to generate the β2M knockout cell line, which does not express endogenous cell surface MHC Class I HLA molecules (HLA-A or HLA-B) as measured by fluorescence-activated cell sorting (FACS). (sigmaaldrich.com)
  • Tested for Mycoplasma, bacterial and fungal content, post-freeze viability, and short terminal repeat (STR) analysis for cell line identification. (sigmaaldrich.com)
  • This cell line has been recommended as a control cell line for use with the Telomere PNA Kit/FITC for flow cytometry from DakoCytomation. (sigmaaldrich.com)
  • We previously found that ziram, a carbamate pesticide, significantly reduced perforin, granzyme A (GrA), granzyme B (GrB), granzyme 3/K (Gr3/K), and granulysin (GRN) levels in NK-92MI cells, a human natural killer (NK) cell line. (researchgate.net)
  • The differences in extracellular ATP/AMP accumulation correlated with cell-line-specific expression of ectonucleotidases that metabolized the released ATP/AMP. (aspetjournals.org)
  • Combined treatment of FWGE and 5-fluorouracil or dacarbazine resulted in a synergistic effect in the HCR-25 human cancer cell line and B16 murine melanoma cell line [ 6 ]. (hindawi.com)
  • Herein we report that DCPA attenuates the normal elevated and sustained [Ca2+](i) that follows internal store depletion in the human leukemic Jurkat T cell line and primary mouse T cells. (cdc.gov)
  • This size is consistent with that of B cell CR2 mRNA. (nih.gov)
  • Analysis of Jurkat and Raji mRNA by PCR demonstrated the presence of this novel splice variant in both cell lines. (nih.gov)
  • Fig. 2: Anti-CD80 TKMG48 enables PD-1 to inhibit T cell activation in the presence of CD80. (nature.com)
  • Fig. 3: Anti-human CD80 TKMF5 enables human PD-1 to inhibit T cell activation in the presence of human CD80 by dissociating cis duplex of human PD-L1 and CD80. (nature.com)
  • This binding results in the activation have been implicated with streptococcal toxic shock syn- of a large proportion of antigen-presenting cells and T drome (STSS). (cdc.gov)
  • Ectopic Mcl-1 expression attenuates Bak activation and apoptosis by ABT-737 + roscovitine, whereas cells overexpressing Bcl-2 or Bcl-xL remain fully sensitive. (aacrjournals.org)
  • Robust extracellular ATP/AMP accumulation was observed in the FADD-deficient cells during necroptosis, but not during apoptotic activation of Panx1 channels. (aspetjournals.org)
  • Apoptotic activation triggered equivalent proteolytic gating of Panx1 channels in all three Jurkat cell lines. (aspetjournals.org)
  • Differential expression of particular ectonucleotidases in tumor cell variants will determine whether chemotherapy-induced activation of Panx1 channels drives accumulation of immunostimulatory ATP versus immunosuppressive adenosine within the tumor microenvironment. (aspetjournals.org)
  • Caspase-3 activation is a cell requirement during early stages of the skeletal myoblast differentiation. (wikipedia.org)
  • Caspase signals resulting from the activation of nuclease CAD indicate that the cell differentiation is due to a CAD modification in chromatin structure. (wikipedia.org)
  • The cell diversity is originated by cell differentiation, which has been attributed to the activation of specific transcription factors. (wikipedia.org)
  • 3,4-Dichloropropionanilide (DCPA) inhibits T-cell activation by altering the intracellular calcium concentration following store depletion. (cdc.gov)
  • Influx of calcium (Ca2+) from the extracellular environment, following internal Ca2+ store depletion, provides the elevated and sustained intracellular calcium concentration ([Ca2+](i)) critical for optimal T-cell activation. (cdc.gov)
  • Taken together, these data indicate that DCPA inhibits T-cell activation by altering Ca2+ homeostasis following store depletion. (cdc.gov)
  • Although only two SpeC residues (Tyr(15) and Arg(181)) are critical for activation of virtually all human CD3(+) T cells, a larger cluster of four hot spot residues are required for interaction with Vbeta2.1. (uwo.ca)
  • In this study, the protective effect of a fermented wheat germ extract (FWGE) against LPS-induced inflammation and oxidative stress in IPEC-J2 porcine intestinal epithelial cells was studied. (hindawi.com)
  • and how oxidative stress is associated with the biological processes underlying human ageing. (otago.ac.nz)
  • Our study shows that Jurkat human T cells have a molecule that reacts with both anti-CR2 antibodies and the third component of complement, C3. (nih.gov)
  • Reacts with human ANXA8 / Annexin A8. (covalab.com)
  • After 24 hours 65% of cells were annexinV and propidiumiodide positive (late apoptotic cells, LA). EA and LA cells were incubated with FITC labeled SAP in the presence or absence of Ca 2+ and subsequent binding was measured by flowcytometry. (biomedcentral.com)
  • Fig. 4: Anti-CD80 TKMG48 augments PD-1-binding capacities of DCs and suppresses antigen-specific T cell responses in vivo. (nature.com)
  • RELA tunes innate-like interferon I/III responses in human T cells. (nih.gov)
  • Accumulation of extracellular ATP/AMP was similarly absent in RIP1-deficient Jurkat cells during apoptotic responses to chemotherapeutic agents. (aspetjournals.org)
  • Infections caused by pathogenic bacteria and consequent inflammatory responses can cause human disease and can result in significant economic losses in animal industry. (hindawi.com)
  • In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. (lu.se)
  • HUVEC cells were subjected to SDS PAGE followed by western blot with 11265-1-AP (CD31 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. (ptglab.com)
  • Be the first to review Human Jak3 Alexa Fluor® 594-conjugated Antibody and earn rewards! (rndsystems.com)
  • Have you used Human Jak3 Alexa Fluor® 594-conjugated Antibody? (rndsystems.com)
  • These monoallelic HLA cell lines can be used to study peptide binding and presentation in the context of individual HLA subtypes. (sigmaaldrich.com)
  • Synthetic peptide surrounding aa 316 of human Annexin VIII. (covalab.com)
  • Synthetic peptide within Human Cleaved PARP1 aa 200-300. (abcam.com)
  • Two cDNA clones were identified upon screening of a Jurkat cell cDNA library with the B cell CR2 cDNA. (nih.gov)
  • Exposure of Jurkat cells to either DCPA or 50 mu M 2-APB attenuated the increase in [Ca2+](i) following thapsigargin or anti-CD3 induced store depletion in a similar manner. (cdc.gov)
  • SAP depletion of serum resulted in a 50% decrease of PI for LA cells, and complete restoration of PI could be demonstrated with SAP reconstitution up to 100 μg/ml. (biomedcentral.com)
  • SAP depletion had no effect on PI of EA cells. (biomedcentral.com)
  • Chen, L. & Flies, D. B. Molecular mechanisms of T cell co-stimulation and co-inhibition. (nature.com)
  • ED 50 = 10 - 50 ng/ml, corresponding to a specific activity of 0.02 - 0.1 x 10 6 units/mg, as determined by inhibition of apoptotic cell death induced by FASL on Jurkat cells. (biolegend.com)
  • Autophagic cell death was excluded as the inhibition of autophagy did not attenuate the cytotoxicity. (spandidos-publications.com)
  • Jurkat cells can produce interleukin 2, and are used in research involving the susceptibility of cancers to drugs and radiation. (wikipedia.org)
  • Cytotoxicity activities of the crude ethanol extracts from Chamaecostus subsessilis and Chamaecostus cuspidatus and the fractions obtained by liquid-liquid partition were observed when these species were assayed against a panel of six human cancer cell lineages (HL60, Jurkat, MDA-MB231, MCF-7, HCT, THP-1) and normal (Vero) cells using the MTT colorimetric assay. (iomcworld.com)
  • FAS was initially purified and cloned from SKW6.4 cells and a cDNA library of human T cell lymphoma KT-3 cells. (biolegend.com)
  • We analyzed 19 acute-phase serum sam- cells, with subsequent release of high systemic levels of ples for mitogenic activity from patients with severe strepto- cytokines (12-15). (cdc.gov)
  • VWR provides the cell culture community with access to the most reliable supply of exceptional quality Fetal Bovine Serum: VWR Life Science Seradigm. (vwr.com)
  • caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death. (enzolifesciences.com)
  • Caspase 3 is responsible for cellular differentiation, although it is unclear how this kind of protein can promote the cell apoptosis. (wikipedia.org)
  • Asymmetric inheritance of organelle and cellular compounds between daughter cells impacts on the phenotypic variability and was found to be a hallmark for differentiation and rejuvenation in stem-like cells as much as a mechanism for enhancing resistance in bacteria populations. (biorxiv.org)
  • For this porpoise, we use multiple live cell markers which permit us both to follow the partitioning process for multiple generations and to investigate the correlations between the partitioning of different cellular constituents. (biorxiv.org)
  • Immunoprecipitation experiments with anti-CR2 antibodies and SDS-PAGE analysis reveal a protein with an apparent molecular mass of 155 kDa which is higher than the one seen in B cells. (nih.gov)
  • In this study, we tested the hypothesis that tumor-infiltrating T cells could be more effectively activated and redirected by oncolytic adenoviruses that were armed with bispecific T-cell-engager (BiTE) antibodies. (aacrjournals.org)
  • We have learned that genes in mammalian cells are transcribed into messenger RNAs (mRNAs), which are to be translated into polypeptides (proteins). (intechopen.com)
  • Molecular mechanisms of the initiation of transcription from TATA box have been well known as the most essential nuclear events in mammalian cells. (intechopen.com)
  • SAP binds to apoptotic cells. (biomedcentral.com)
  • We evaluated SAP binding to early and late apoptotic cells and whether this binding has functional consequences for the phagocytosis of these cells. (biomedcentral.com)
  • After 4 hours 40% of cells stained with annexinV, and were propidiumiodide negative (early apoptotic cells, EA). (biomedcentral.com)
  • This might have consequences for diseases in which phagocytosis of early apoptotic cells is decreased. (biomedcentral.com)
  • HA14-1) that disable Bcl-2, resulting in induction of apoptosis in leukemia cell lines ( 8 ). (aacrjournals.org)
  • Pannexin-1 (Panx1) channels mediate the efflux of ATP and AMP from cancer cells in response to induction of extrinsic apoptosis by death receptors or intrinsic apoptosis by chemotherapeutic agents. (aspetjournals.org)
  • FWGE has significant antiproliferative effects and kills tumour cells by the induction of apoptosis via the caspase-poly (ADP-ribose) polymerase pathway [ 9 ]. (hindawi.com)
  • It breaks up the DNA during apoptosis and promotes cell differentiation. (wikipedia.org)
  • CAD leads to the initiation of the DNA strand breakage, which occurs during terminal differentiation of some cell, such as skeletal muscle cell. (wikipedia.org)
  • Targeting of p21 promoter is responsible for inducing cell differentiation, which is promoted by modifying the DNA nuclear microenvironment. (wikipedia.org)
  • For this purpose, we first compared the ability of G and N proteins of a pathogenic and a nonpathogenic strain to trigger apoptosis of Jurkat rtTA by using an inducible Tet-on expression system. (pasteur.fr)
  • MISSION ® lentivirus was used to generate the ten (10) monoallelic HLA cell lines, which express individual HLA-A or HLA-B subtypes on the cell surface via a β2M:HLA fusion protein as described in Nature Biotechnology 35, 765-772, (2017) and as demonstrated via FACS analysis. (sigmaaldrich.com)
  • Abundant evidence implicates this protein in the suppression of apoptosis in many types of cells. (bdbiosciences.com)
  • Changes to insulin sensitivity in glucose clearance systems and redox following dietary supplementation with a novel cysteine-rich protein: A pilot randomized controlled trial in humans with type-2 diabetes. (otago.ac.nz)
  • The transplantation of cells or tissues has been applied for treating various human diseases (Bhatia et al. (springer.com)
  • Although the LAT family plays important roles in the development and function of normal tissues, they are frequently increased in cancer cells ( 3 ). (spandidos-publications.com)
  • The I 9.2 and I 2.1 cell lines. (wikipedia.org)
  • Unlike wild type Jurkat cells, which express multiple HLA subtypes, the Jurkat HLA panel cell lines express individual MHC Class I HLA subtypes. (sigmaaldrich.com)
  • DNA, RNA, cDNA derived from ECACC mammalian cell lines allow screening for genes or expression patterns to identify lines most suitable for specific research. (sigmaaldrich.com)
  • found that FWGE can promote apoptosis in different types of cancer cell lines such as SNU-5, MKN-45, SNU-620, SNU-1, and SNU-16. (hindawi.com)
  • Whether the same processes take place in the context of cancer cell lines is still poorly investigated. (biorxiv.org)
  • This helps us understand the high phenotypic variability reported in these cancer cell lines. (biorxiv.org)
  • Under AAS culture conditions, the cell killing effect of GEF was synergistically pronounced in the EGFR-expressing cell lines, namely, CAL 27, Detroit 562, A549 and PANC-1 cells compared with those treated with either GEF or AAS alone. (spandidos-publications.com)
  • EBV infects cells via the CR2 that was previously thought to be expressed only on the surface of B cells and certain epithelial cells. (nih.gov)
  • Our comprehensive approach, including mutagenesis, functional readouts from both bulk T cell populations, and an engineered Vbeta2.1(+) Jurkat T cell, as well as surface plasmon resonance binding analysis, has defined the SpeC "functional epitope" for TCR engagement. (uwo.ca)
  • The panel can also be used to develop cell-based assays to evaluate candidate cancer immunotherapies and identify tumor-specific neoantigens. (sigmaaldrich.com)
  • His interests then broadened to the impact of these oxidants on neighbouring cells during inflammation, and the controlled generation of oxidants by other cells during normal metabolism. (otago.ac.nz)
  • Human FAS, amino acids (Arg17-Asn173) (Accession# NM_000043), was expressed in 293E cells. (biolegend.com)
  • The addition of essential amino acids, but not non-essential amino acids to the cell culture medium resulted in the cancellation of this pronounced cytotoxicity. (spandidos-publications.com)
  • The members of the L-type amino acid transporter (LAT) family are Na + -independent transporters that deliver neutral amino acids into cells ( 2 ). (spandidos-publications.com)
  • Homo sapiens (Human) USCN(Wuhan USCN Business Co., Ltd. (uscnk.com)
  • It has unusually long telomeres, useful in tests where telomere length is determined, where it can be used as control cells with known telomere length. (sigmaaldrich.com)