• In humans, a major roadblock in achieving successful SCNT leading to embryonic stem cells has been the fact that human SCNT embryos fail to progress beyond the eight-cell stage. (news-medical.net)
  • They derived several human embryonic stem cell lines from these cloned embryos whose DNA was an exact match to the adult cell that donated the DNA. (news-medical.net)
  • No objective, even though noble in itself, such as a foreseeable advantage to science, to other human beings or to society, can in any way justify experimentation on living human embryos or foetuses, whether viable or not, either inside or outside the mother's womb. (archdiocese-no.org)
  • To create embryos with the intention of destroying them, even with the intention of helping the sick, is completely incompatible with human dignity, because it makes the existence of a human being at the embryonic stage nothing more than a means to be used and destroyed. (archdiocese-no.org)
  • Embryonic stem cell research "uses special cells found in three-to-five day old human embryos to seek cures for a host of chronic disease" (PRC). (ipl.org)
  • Specifically, the disputes are aroused by the issues of human cloning, which presumes artificial production of living beings, and stem cell research that requires killing the embryos. (prime-essay.org)
  • Furthermore, the individuals who are against using embryos' biomaterial for stem cell research base their rationale on the belief that these embryos are already separate individuals. (prime-essay.org)
  • Summing up the above-mentioned, it is appropriate to state that despite the hostile attitude towards contemporary genetic engineering (in particular, human cloning and using human embryos for stem cell research) the enhancement of life quality is more relevant. (prime-essay.org)
  • Most human embryos reproduced by most human cloning techniques would actually be genetically unique -- i.e., having never existed before. (lifeissues.net)
  • The legislation, which bans reproductive cloning as well as embryonic stem cell research in which human life is destroyed, was amended in the House last week to outlaw the cloning process to create human embryos for research, but would allow importation of embryonic stem cell lines created outside the state for research. (lifenews.com)
  • Elsewhere on this site I describe my own conversations with a British scientist in the 1980s who was attempting then to clone human embryos - with some success. (globalchange.com)
  • The stem cells suits human needs, does not cause harm and can be obtained from both adult and fetal does not conflict with religious beliefs, it has tissues, umbilical cord and early embryos. (who.int)
  • Unicellular for those cells that are derived from human organisms are primed to replicate (clone) pre-embryos, which seem to have a high themselves by nature. (who.int)
  • 2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
  • 3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
  • 7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
  • 3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
  • 5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
  • Many of these accurate definitions can also be used in bills and treaties concerning related issues, e.g., human embryonic stem cell research, human genetic engineering, abortion, the use of abortifacients, conscience clauses, IVF and other artificial reproductive technology research and regulation, etc. (lifeissues.net)
  • Note that each and every individual "loophole" discussed below that permits human cloning by default (and most bills have literally dozens of such loopholes) thus permits it for both "therapeutic" and for "reproductive" human cloning. (lifeissues.net)
  • Governor Blanco discussed the bills with the Louisiana Coalition for Ethical Stem Cell Research on the final day of the session, and said that bills banning reproductive cloning but allowing for destructive embryonic research, such as the one sponsored by Senate President Don Hines (D-Bunkie), would not receive her support. (lifenews.com)
  • These preparatory interregional and interdisciplinary meetings focused on the following areas: cloning and human reproductive health, biologicals, organ transplantation, research, and medical genetics. (who.int)
  • The main objection to the use of human cloning for reproductive purposes is that it would be contrary to human dignity as it would violate the uniqueness and indeterminateness of the human being. (who.int)
  • Some, however, consider that reproductive cloning could be acceptable in certain cases, such as otherwise untreatable infertility, or to avoid inherited genetic diseases. (who.int)
  • In terms of existing ethical guidelines for biomedical research involving human subjects, human cloning for reproductive purposes raises concerns about risk in relation to benefit, informed consent, and accountability. (who.int)
  • Human cloning for reproductive purposes is seen as having the potential to disrupt intergenerational relations and family structures, with major psychological, social and legal consequences for the individuals and communities concerned. (who.int)
  • Some also perceive reproductive cloning as a high-technology intervention of little relevance to the health needs of the vast majority of the world's population. (who.int)
  • Before the announcement in February 1997 of the cloning of a sheep by somatic cell nuclear transfer, existing legislation in a number of countries already precluded human cloning for reproductive purposes, sometimes implicitly. (who.int)
  • Since then, many countries have adopted government decrees or introduced legislation to impose an explicit ban on human cloning for reproductive purposes. (who.int)
  • Cloning technology, however, is perceived as having the potential for reproductive cloning, which raises serious ethical and moral concerns. (who.int)
  • Reproductive cloning versus germ cell (egg, ovum). (who.int)
  • Several members of the chemokine-receptor family serve, in conjunction with CD4, as receptors for the entry of human immunodeficiency virus type I (HIV-1) into cells. (nih.gov)
  • SIV strains will also infect CD4+ cells that lack CCR5, which suggests that these strains use as yet unidentified receptors. (nih.gov)
  • Here we use an expression-cloning strategy to identify SIV receptors and have isolated genes encoding two members of the seven-transmembrane G-protein-coupled receptor family that are used not only by SIVs, but also by strains of HIV-2 and M-tropic HIV-1. (nih.gov)
  • Usage of these new receptors following experimental infection of non-human primates with SIV strains may provide important insight into viral transmission and the mechanisms of SIV- and HIV-induced acquired immune-deficiency syndrome. (nih.gov)
  • Sequencing of the T-cell receptors of the OspA reactive clones showed significant skewing of the T-cell receptor repertoire. (ox.ac.uk)
  • To address whether the expression of the CD8 receptor on the cell membrane was associated to differences in the physiology of the T-cells, we isolated, from the same clone, CD4 single positive (SP) cells from those co-expressing CD4/CD8 receptors (DP cells) and stimulated them in vitro with antigen presenting cells (APC) carrying TSHR. (uninsubria.it)
  • Understanding of the molecular interactions between T cell receptors (TCR) and self-epitopes may explain how T cells escape thymic education and initiate an autoimmune reaction. (ox.ac.uk)
  • Restricted T cell receptor expression by human T cell clones specific for mycobacterial 65-kDa heat-shock protein: selective in vivo expansion of T cells bearing defined receptors. (ox.ac.uk)
  • The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)
  • Although attempts have not yet been made to create a therapeutic transplant from embryonic stem cells, the methods have been developed to allow the creation of functional, mature cells using human cell cloning technology. (news-medical.net)
  • From the ethical point of view, so-called therapeutic cloning is even more serious. (archdiocese-no.org)
  • It is gravely immoral to sacrifice a human life for therapeutic ends. (archdiocese-no.org)
  • Since some therapeutic approaches in various human diseases are based on the manipulation of helper and suppressor functions, the question whether committed suppressor cells exist has important practical implications in medicine. (ox.ac.uk)
  • Therapeutic cloning possesses enormous potential for revolutionizing medical and thera- peutic techniques. (who.int)
  • This is therapeutic cloning. (who.int)
  • This cell then has therapeutic cloning: the global the capacity to divide and grow into an exact replica of the original from whom the debate somatic cell was taken. (who.int)
  • SCNT is a method of cloning mammalian cells that can be used to create personalized embryonic stem cells from an adult animal or human. (news-medical.net)
  • Embryonic stem cells are immortal, and have the potential to develop into any type of adult cell, even after months growing in culture dishes. (news-medical.net)
  • By transferring adult cell DNA into an embryonic stem cell, it is possible to create a line of immortal embryonic cells that are able to develop into any type of adult cell, genetically identical to the donor. (news-medical.net)
  • The cloning method is based on the fact that cytoplasmic factors in mature, metaphase II oocytes are able to reset the identity of a transplanted adult cell nucleus to an embryonic state. (news-medical.net)
  • This was the first successful reprogramming of human somatic cells into embryonic stem cells using a cloning technique, SCNT. (news-medical.net)
  • Dermal fibroblasts were taken from a 35-year old male and a 75-year-old male and used to create embryonic stem cells. (news-medical.net)
  • The adult cell nuclei were transferred into metaphase-II stage human oocytes, producing a karyotypically normal diploid embryonic stem cell line from each of the adult male donor cells. (news-medical.net)
  • Help us to be faithful to this sacred trust so that we may protect and promote the dignity of every human life from the very moment of conception, particularly the tiniest humans in the embryonic stage of human development who are so often forgotten by society & used by modern science. (archdiocese-no.org)
  • In fact to get a embryonic stem cell a human embryo has to be disassembled. (ipl.org)
  • but one of the most arguable topics of all time is the use of embryonic stem cells. (ipl.org)
  • In recent years, several competing viewpoints have emerged about embryonic stem cell research. (ipl.org)
  • All of this debate raises an important question, Should embryonic stem cell research be conducted for treatment of present and future diseases? (ipl.org)
  • People who believe that an embryo should not be destroyed tend to say that embryonic stem cell research should not be conducted. (ipl.org)
  • On the other hand, people who believe that embryonic stem cell research creates means of curing diseases reply that the research should be conducted. (ipl.org)
  • Embryonic stem cell transplants have been an ethical, social, and legal controversy since the first successful transplant of human stem cells in 1998. (ipl.org)
  • However, there is hope for the future as Governor Kathleen Blanco told pro-life advocates that she does not support embryonic stem cell research, and favors the wholesale cloning bans that pro-life organizations had backed. (lifenews.com)
  • During debate on his bill, Beard stated that opponents of his bill place a 'false hope' in embryonic stem cell research. (lifenews.com)
  • As of yet no useful embryonic stem cell lines have been created, and all breakthroughs in stem cell research have been done with adult stem cells, which do not require the destruction of human life. (lifenews.com)
  • Judging by the successful growth of the combined human-cow clone creation it appears that cow mitochondria may well be compatible with human embryonic development. (globalchange.com)
  • Some people are very uneasy about creating a human embryo and then dismembering it, however early the stage, to obtain embryonic stem cells from which useful tissues might be grown. (globalchange.com)
  • they might feel more comfortable with a hybrid solution, if it were shown that the embryonic cow-human stem cells were viable as tissue producers but not capable of becoming a baby. (globalchange.com)
  • The stage-specific embryonic antigen 4 (SSEA4) is com- isolate the NSCs from neonatal mice and rats (Campos monly used as a cell surface marker to identify the pluri- et al. (lu.se)
  • 2005). Notch1 and syndecan-1 potent human embryonic stem (ES) cells. (lu.se)
  • Immunohisto- have been used for positive selection of NSCs from em- chemistry on human embryonic central nervous system bryonic mice (Nagato et al. (lu.se)
  • Human cloning is intrinsically illicit in that, by taking the ethical negativity of techniques of artificial fertilization to their extreme, it seeks to give rise to a new human being without a connection to the act of reciprocal self-giving between the spouses and, more radically, without any link to sexuality. (archdiocese-no.org)
  • The use of the technique of nuclear transfer for reproduction of human beings is surrounded by strong ethical concerns and controversies and is considered a threat to human dignity. (who.int)
  • This technique is surrounded by strong ethical concerns and is considered a threat to human dignity. (who.int)
  • We want real cures now available from ethical adult stem cell research, not illusory promises from unproductive embryo research,' the Louisiana Coalition for Ethical Stem Cell Research said in a statement. (lifenews.com)
  • It reports on implementation of resolution WHA50.37 concerning ethical, scientific and social implications of cloning in human health. (who.int)
  • Resolution WHA50.37 requested the Director-General to clarify the potential applications of cloning procedures in human health and their ethical, scientific and social implications. (who.int)
  • The principal receptor for entry of macrophage-tropic (M-tropic) HIV-1 strains is CCR5, whereas that for T-cell-line-tropic (T-tropic) strains is CXCR4. (nih.gov)
  • In this study we characterized a subset of CD4+ clones, from a healthy donor, that is specific for the thyrotropin receptor (TSHR) and that showed cells co-expressing the CD8 receptor. (uninsubria.it)
  • In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. (wikipedia.org)
  • Human self-reactive T cell clones expressing identical T cell receptor beta chains differ in their ability to recognize a cryptic self-epitope. (ox.ac.uk)
  • We have examined the T cell receptor (TcR) expression of clones specific for epitopes of mycobacterial 65-kDa heat-shock protein (hsp65) in the context of two different HLA molecules, and used this system as a model to assess the selection of T cells responsive to this antigen in vivo. (ox.ac.uk)
  • This means that anything that happens to the embryo from that point onward is the harming of a human being. (ipl.org)
  • The destruction and use of a human embryo should not be allow to happen. (ipl.org)
  • 2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
  • Thus to use the phrase "of an existing or previously existing human being" to refer to the product of human cloning would not be a scientifically accurate description of the cloned or genetically engineered human embryo -- thus creating yet another loophole in the bill or treaty. (lifeissues.net)
  • Ellington, who refused to compromise even at the urging of Gov. Blanco, said his support stems from his views that the embryo is not a human life. (lifenews.com)
  • Characterization of in vivo expanded OspA-specific human T-cell clones. (ox.ac.uk)
  • If cloning were to be done for reproduction, this would impose on the resulting individual a predetermined genetic identity, subjecting him - as has been stated - to a form of biological slavery, from which it would be difficult to free himself. (archdiocese-no.org)
  • nevertheless, many people express hostility towards genetic engineering justifying their attitude with the objection that humans should not play God. (prime-essay.org)
  • A clone is an organism that is a genetic copy of an existing one. (who.int)
  • 1. What genetic information is required to clone a human or an animal? (scienceteacherprogram.org)
  • Associated with new knowledge on the human genome, it could be used to facilitate genotype selection and encourage social and parental intolerance of disability or, potentially, perceived genetic defects. (who.int)
  • Complete sequencing of both alpha and beta chains of a subset of clones showed that at least two distinct T-cell clones were expanded in vivo. (ox.ac.uk)
  • In normal human subjects a small proportion of peripheral blood T-cells simultaneously express both CD4 and CD8 differentiation antigens. (uninsubria.it)
  • WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)
  • We have studied five human in vivo activated T cell clones specific for the region 535-551 of human thyroid peroxidase (TPO) established from a Graves' patient. (ox.ac.uk)
  • Our findings define a route by which human self-reactive T cells may escape thymic selection and become activated in vivo, thus possibly leading to autoimmunity. (ox.ac.uk)
  • Moreover, The use of animals as surrogate rine host, can provide a platform for animal models for tumour viruses in hosts for the study of human tu- in vivo infection. (who.int)
  • For instance, mice are able to reconstitute most lymphomas in monkeys and humans woodchuck hepatitis virus induces major components of the human provides strong support for a direct hepatocellular carcinoma (HCC) haematolymphoid system including oncogenic role of EBV in vivo. (who.int)
  • Several international health-related professional associations and religious bodies have issued statements calling for the careful monitoring and regulation of scientific developments in the field of cloning and human genetics. (who.int)
  • It is suggested that a single T cell clone, depending on the signals it receives from its environment, may release either helper or suppressor cytokines. (ox.ac.uk)
  • We have shown that thyroid epithelial cells (TEC), the only cells that produce TPO, express HLA class II molecules in Graves' disease and can act as an antigen-presenting cells, presenting TPO after endogenous processing to autoantigen-reactive T cell clones. (ox.ac.uk)
  • DR3-restricted clones were raised from both the synovial fluid (SF) and peripheral blood (PB) of a patient with reactive arthritis in three separate cloning events. (ox.ac.uk)
  • Fine epitope mapping using nested peptides showed that clones using identical TCR beta chains, identical V alpha, but a different J alpha recognized distinct, nonoverlapping epitopes in the TPO 535-551 region. (ox.ac.uk)
  • General Assembly the adoption of a declaration on human cloning by which Member States were called upon to prohibit all forms of human cloning inasmuch as they are incompatible with human dignity and the protection of human life. (who.int)
  • Additionally, Gov. Blanco's now-apparent position could further influence legislators to pass a wholesale cloning ban. (lifenews.com)
  • Often aborted babies are harvested for Stem Cell Research. (archdiocese-no.org)
  • STEM CELL RESEARCH is a very controversial topic in today's time. (ipl.org)
  • Stem cell research is not worth supporting. (ipl.org)
  • Advocates of stem cell research believe that the cells are not equivalent to human life because it is inside the womb even facing the fact that the start of a human life is in the moment of conception. (ipl.org)
  • To ensure better health conditions and general prosperity of the future generations, the contemporaries should consider the necessity of stem cell research, as well as acknowledge the relevance to create the needed biomaterial artificially. (prime-essay.org)
  • Finally, the cloners see that there is no political stability for their clone and kill labs in Louisiana, meaning that effective adult stem cell research can continue to thrive in Louisiana," concluded Bordlee. (lifenews.com)
  • One of the greatest controversies triggered tissue, a stem cell encoding for heart tissue by the rapid pace of evolution in biology, will eventually develop into heart tissue particularly in genomics and biotechnology, and so on. (who.int)
  • When the nucleus of a stem cell has been the technique of cloning. (who.int)
  • The con- is removed and replaced by a nucleus of cept of human cloning has long been in the another cell type, the stem cell will then imagination of many scientists, scholars and be reprogrammed to produce the product fiction writers [ 1 ]. (who.int)
  • To confirm that clones 37 (and its sisters) and 43 recognize different epitopes, the T cell clones were stimulated with a TPO-transfected autologous Epstein-Barr virus (EBV) cell line (TPO-EBV) that presents TPO epitopes afer endogenous processing. (ox.ac.uk)
  • Topics covered will include cell membrane structure and function, metabolism, cell motility and division, genome structure and replication, the regulation of gene expression and protein production, genotype to phenotype relationship, and basic principles of inheritance. (middlebury.edu)
  • A panel of CD4 T-cell clones was isolated from synovial fluid by single cell flow cytometry from a patient with treatment-resistant Lyme arthritis using a DRB1*0401 major histocompatibility complex (MHC) class II tetramer covalently loaded with outer surface protein A (OspA) peptide164-175, an immunodominant epitope of Borrelia burgdorferi. (ox.ac.uk)
  • In addition, T-cell clones were tested functionally for their reactivity to the wild-type peptide as well as to altered peptide ligands (APLs) and peptide libraries based on the OspA epitope in order to determine the TCR contact residues and the stringency in T cell recognition. (ox.ac.uk)
  • Only clone 37 and its sisters recognizes the TPO-EBV cell line, suggesting that the epitope recognized by clone 43 is not presented upon endogenous processing. (ox.ac.uk)
  • Subtle differences in epitope specificity were detected for two clones with differing TcR. (ox.ac.uk)
  • WHA50.37, which states "the use of cloning for the replication of human individuals is ethically unacceptable and contrary to human integrity and morality. (who.int)
  • However, it appears that the ability of the In its simplest form, cloning is defined stem cells to transform is limited, except as the exact replication of cells. (who.int)
  • As a decisive step towards the artificial production of human beings, it would increase the risk of reducing people to objects. (who.int)
  • For a start it raises the biggest question of all: how many human genes does a cow or monkey have to gain before we give it human rights? (globalchange.com)
  • only the adeno-associated parvoviruses (members of the dependovirus genus) and B19 are known to infect humans. (cdc.gov)
  • For this reason, the infect humans, this virus can infect cordance between humans and ex- question about tumour site concor- several other species - including perimental animals. (who.int)
  • One cloning technology that has been developed for mammalian and human cells is somatic cell nuclear transfer (SCNT). (news-medical.net)
  • 3. What does the nucleus of a somatic cell contain that is necessary for this process? (scienceteacherprogram.org)
  • This paper outlines the debates prompted through a reproduction mechanism involv- by progress in cloning research, with special ing male and female germ cells. (who.int)
  • Panophthalmitis cells in vitro ( 6 - 10 ). (cdc.gov)
  • These in vitro, and their expression in these human tumour virus. (who.int)
  • For instance, he assumes that the artificial correction of human genes would help to solve the problem of HIV, bird flu and other health issues. (prime-essay.org)
  • 4. How are genes transferred from a sperm to an egg cell? (scienceteacherprogram.org)
  • 8. Draw a diagram of how genomic imprinting theoretically works to turn on a cell s ability to read genes. (scienceteacherprogram.org)
  • They took a cell from Dr Jose Cibelli, a research scientist and combined it with a cows egg from which the genes had already been removed. (globalchange.com)
  • The genes activated and the egg began to divide in the normal way up to the 32 cell stage at which it was destroyed. (globalchange.com)
  • Technically 1% of the human clone genes would have belonged to the cow - the mitochondria genes. (globalchange.com)
  • Monkeys and humans have 97% of genes in common so if the right 1.6% were transferred from a human to a monkey we could land up with a monkey more human than animal. (globalchange.com)
  • And for the theologians another question: how many human genes does an animal have to have to need salvation? (globalchange.com)
  • Inoculation with a high dose strains of LMP1 transgenic mice vide a powerful tool in mechanistic of EBV caused a B-cell lymphopro- were established that express LMP1 studies on the role of individual viral liferative disorder in these mice, under the control of the immunoglob- genes in cancer. (who.int)
  • T cell clone 37 recognizes the TEC, whereas it is stimulated poorly by the TPO loaded to autologous peripheral blood mononuclear cells (PBMC). (ox.ac.uk)
  • 1. What types of animals have been successfully cloned? (scienceteacherprogram.org)
  • But even they omitted to tell us anything until Dolly was seven months old, well over a year after the cloning technique was successfully carried out and a good two to three years perhaps after they began their secretive work. (globalchange.com)
  • Regulatory interactions among autologous T cell clones. (ox.ac.uk)
  • Human bifunctional T cell clones regulate the activity of an autologous T cell clone. (ox.ac.uk)
  • Clone 43, which fails to recognize the TPO-EBV, also fails to recognize the TEC, but is activated by exogenous TPO presented by autologous PBMC. (ox.ac.uk)
  • In addition, the morphogen retinoic acid, alone or in combination with dibutyryl cAMP, gives a 22-fold induction of PDGF alpha R gene promoter activity in human teratocarcinoma cells. (nih.gov)
  • The results demonstrated that CD8 co-expression has a profound effect on the physiology of T helper (Th) cells. (uninsubria.it)
  • The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. (wikipedia.org)
  • Unphosphorylated or inactive STAT5a may suppress tumor growth in colorectal cancer and active STAT5a expression in premalignant and tumor lesions has shown potential as a prognostic marker in oral squamous cell carcinoma. (wikipedia.org)
  • Studies originally showed a correlation between high STAT5a expression and tumor differentiation in mice models, but histopathological analysis of human breast cancer tissue has shown a different trend. (wikipedia.org)
  • Similar studies of TcR expression were carried out on hsp65-specific, DP4-restricted clones derived from the SF of a patient with rheumatoid arthritis by two independent cloning procedures. (ox.ac.uk)
  • Of the 101 T-cell clones sequenced, 81 possessed TCR beta chains that were present in at least one other clone isolated. (ox.ac.uk)
  • Sequencing alpha and beta chains of representative V beta 5.2+ and V beta 5.6+ PB-derived clones revealed TcR which were identical to those utilized by the SF-derived clones, showing that the repertoire for recognition of this antigen is stable over time. (ox.ac.uk)
  • the right to religious freedom has its foundation in the very dignity of the human person as this dignity is known through the revealed word of God and by reason itself. (archdiocese-no.org)
  • This leads to manipulation and abuses gravely injurious to human dignity. (archdiocese-no.org)
  • The basic techniques of of the implanted nucleus, when it fully cloning have been known for some time, and develops. (who.int)
  • Three clones (37, 72, and 73) expressed identical TCR beta and alpha chains rearranging V beta 1.1 and V alpha 15.1, and were considered sister clones. (ox.ac.uk)
  • The alpha chains expressed by V beta 5.2+ and V beta 5.6+ clones were from different families, V alpha 2.4 and V alpha 23.2, respectively. (ox.ac.uk)
  • Once more, T cell clones with identical alpha and beta TcR chains were obtained from the separate cloning procedures, suggesting oligoclonalty of T cells with this defined specificity in the patient's SF. (ox.ac.uk)
  • un tel dialogue prendra en considération non seulement les bienfaits scientifiques mais également les implications morales, éthiques et juridiques. (who.int)
  • Cloning of human cells is a technology that holds the potential to cure many diseases and provide a source of exactly matched transplant tissues and organs. (news-medical.net)
  • genic models are inadequate for number of activated CD8-positive T LMP1 was strongly expressed in the understanding the cancer etiology in cells increased considerably in the lymphoma tissues but was hardly the context of natural viral infection. (who.int)
  • While many people say the use of the cell research is a way to advance medical knowledge and expand treatments, there is no guarantee that the treatments will work. (ipl.org)
  • The "pros" and "cons" of human cloning research have already been dealt with at length in the literature, so they will not be reviewed here. (lifeissues.net)
  • Rather, after having published analyses of dozens of state, national, federal and international legislative attempts to ban human cloning research, I simply wish to offer seriously considered suggestions for the use of scientifically accurate language and definitions to be used in such endeavors in order to prevent loopholes which would result in much human cloning not being really banned. (lifeissues.net)
  • The two other cloning bans, both wholesale bans that would have prohibited the destructive research, overcame many obstacles to come close to passage, and eventually garnered the support of a majority of the legislature. (lifenews.com)
  • Rep. Beard had pointed out that a total human cloning ban does not impede research, as his opponents, including Senator Hines, have accused. (lifenews.com)
  • In this lesson, students act as research scientist and investigate the development of animal and human cloning. (scienceteacherprogram.org)
  • They then report their findings, both orally and visually, to their colleagues at a symposium on cloning research. (scienceteacherprogram.org)
  • Explain to students that they will be acting as teams of research scientist preparing for a symposium on developments in human cloning. (scienceteacherprogram.org)
  • Assign each group one of the following aspects of cloning-related topics to research using all available classroom resources. (scienceteacherprogram.org)
  • They emphasize the need to promote the teaching of ethics in medical education and to establish effective measures to protect developing countries from the risk of unregulated expatriate research involving human subjects. (who.int)
  • Those were spindle removal, donor cell fusion, and cytoplast activation. (news-medical.net)
  • Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. (wikipedia.org)
  • This has led to a lot of interest in SCNT, which is best known as the method used to pioneer whole animal cloning technology, such as Dolly the sheep. (news-medical.net)
  • Let's wind back the clock: these scientists had already carried out successful human nuclear transfer into an unfertilised egg before Dolly the sheep clone had been made. (globalchange.com)
  • But SCNT can also be used to clone human cells for transplant or other therapies. (news-medical.net)
  • In 2013, scientists reported a successful SCNT procedure by modifying the protocol for specific human oocyte biology. (news-medical.net)
  • Another successful attempt at human SCNT was made using cells from two adult males. (news-medical.net)
  • This work was partly supported by in human lymphoid cell lines. (cdc.gov)
  • The mitochondrial DNA of the stem cells, however, matched the donor egg's mitochondrial DNA. (news-medical.net)
  • The resulting cells were pluripotent and could be differentiated into insulin-producing beta cells to restore the function of the pancreas in the donor. (news-medical.net)
  • It can also cause TAC in other conditions in which increased red cell production is necessary to maintain stable red cell indices, as may occur in anemia due to blood loss. (cdc.gov)
  • One exception is hu- humanized SCID mice, the use of al oncogenic viruses that are strictly man T-cell lymphotropic virus type 1 surrogate hosts has not proven very species-specific, causing cancer in (HTLV-1): in addition to its ability to useful for defining tumour site con- humans only. (who.int)
  • In this combined immunodeficiency (SCID) cancer is low in these species (as it chapter, some aspects of this issue mice, in which the human target is in humans), which renders cancer are discussed. (who.int)
  • 1 Department of Cell Biology, University of Nijmegen, The Netherlands. (nih.gov)
  • The lesson is this: today's headlines on human cloning tell us history. (globalchange.com)
  • Animal models for human tumour mental animals is not easy to answer does induce adult T-cell leukaemia/ viruses that make use of animal virus- for these agents, because cancer bi- lymphoma (ATLL), albeit in monkeys es are scarce. (who.int)
  • If the clone had been allowed to continue beyond implantation it would have developed as Dr Cibelli's identical twin. (globalchange.com)
  • These cells have been sought after as potential therapies for diseases ranging from heart disease to Parkinson's to cancer. (news-medical.net)
  • Inhibiting these molecules has been shown to increase neuroprotection, enhance axonal regeneration, and facilitate the implementation of cell replacement therapies. (bvsalud.org)
  • that is histopathological y very simi- T cel s, B cel s, natural kil er cel s, LMP1 of EBV can transform ro- lar to that caused by hepatitis B vi- macrophages, and dendritic cells, dent fibroblasts and is expressed rus (HBV) in humans, but it does so and this humanized mouse model in most of the human cancers as- through a different mechanism. (who.int)