• In her current position as a biologist, her focus on human DNA polymerases continues and expands towards studying genome-wide gene expression changes in yeast strains. (nih.gov)
  • Here, we examined the expression of the HE4 gene and protein in a large series of normal and malignant adult tissues by oligonucleotide microarray and tissue microarray, respectively. (nature.com)
  • In a series of 175 human adult tumors, gene expression was highest in ovarian serous carcinomas. (nature.com)
  • Using tissue microarrays and full tissue sections of normal and 448 neoplastic tissues, HE4 immunoreactivity was found in normal glandular epithelium of the female genital tract and breast, the epididymis and vas deferens, respiratory epithelium, distal renal tubules, colonic mucosa, and salivary glands, consistent with HE4 gene expression. (nature.com)
  • Knowledge of the expression patterns of HE4 in our survey is useful for application in histopathologic diagnosis, and should be taken into consideration in future studies that examine the role of HE4 as a serological tumor biomarker or as a target for gene-based therapy. (nature.com)
  • Here, we used oligonucleotide and tissue microarrays to survey HE4 gene and protein expression in a large group of malignant and normal tissues from adults. (nature.com)
  • HE4 is one of more than 8900 different human genes represented on U95a GeneChips (Affymetrix, Santa Clara, CA, USA), which we used previously to develop a molecular classification of 175 human carcinomas based on patterns of gene expression. (nature.com)
  • 18 With the exception of the ovarian neoplasms, the same carcinomas analyzed for gene expression were also examined for HE4 by immunohistochemistry on tissue microarrays (see below). (nature.com)
  • By examining the relationship between these non-coding RNAs and the hGH gene, researchers hope to understand how these remote regions impact hGH gene expression and dysfunction. (sciencedaily.com)
  • Although non-coding RNAs fail to produce functional proteins, researchers believe that in some cases these RNAs may control gene expression. (sciencedaily.com)
  • While mutations to the hGH gene often lead to abnormal growth in children and adults, these mutations have provided researchers with key clues regarding the genomic areas that appear to control expression of the hGH gene. (sciencedaily.com)
  • This blockade led to the five-fold repression of hGH gene expression. (sciencedaily.com)
  • FANTOM, a large international consortium led by RIKEN releases today the first comprehensive map of gene activity across the human body, and provides the first holistic view of the complex networks that regulate gene expression across the wide variety of cell types that make up a human being. (riken.jp)
  • Using a highly sensitive technique called Cap Analysis of Gene Expression (CAGE), developed at RIKEN (ref. 4, 5), the researchers monitored the activity of promoters and enhancers across over 180 human primary cells. (riken.jp)
  • Unlike other large-scale genomics projects, FANTOM5 focused on identifying gene expression on normal primary cells rather than cell lines derived from cancers. (riken.jp)
  • SCIENCE TRANSLATIONAL MEDICINE Scientists at Massachusetts General Hospital and Harvard Medical School have-for the first time-imaged epigenetic regulation of gene expression in the living human brain. (the-scientist.com)
  • The team applied its modified PET imaging approach on eight healthy volunteers, monitoring where the HDACs were switching off brain gene expression over time. (the-scientist.com)
  • Here, we defined the single-cell spatiotemporal gene expression landscape of human embryonic development with stem-cell-derived organoids. (newswise.com)
  • In humans, mRNA expression of hTERT ( hEST2 ), the candidate telomerase catalytic subunit gene, appears to parallel the levels of telomerase enzyme activity, suggesting that induction of hTERT is necessary and perhaps sufficient for expression of telomerase activity in tumor cells. (nature.com)
  • The results of these analyses revealed that the differentially expressed exosomal miRNAs participate in multiple biological processes, such as gene expression, synthesis of biomolecules, cell development, differentiation, and signal transduction, among others. (hindawi.com)
  • This study aims to explore its mechanism by defining changes in gene expression between neoplastic and normal tissue samples before and after treatment. (karger.com)
  • The up-regulation of proto-oncogene may be the consequence of epigenetic control of gene expression by demethylase, and mbd2 is involved in the regulation of hMSH2 expression in human gastric cancer. (wjgnet.com)
  • Gene expression signature of human neuropathic pain identified through transcriptome analysis. (iasp-pain.org)
  • Previous data has reported similarity between human brain and testis gene expression patterns. (karger.com)
  • Hence, it means that human testis could also play a crucial role in human speciation if these two tissues exhibit similar gene expression patterns. (karger.com)
  • Determining the large scale anatomy of gene expression patterns of various human tissues could draw a more convincing conclusion, and better our understanding of the correlation/inter-correlation among different tissues. (karger.com)
  • Among the 17 tissues, the highest similarity in gene expression patterns was between human brain and testis, based on DDD and clustering analysis. (karger.com)
  • Present results provide evidence to support the proposal that human testis and brain share the highest similarity of gene expression patterns. (karger.com)
  • Audic S, Claverie JM: The significance of digital gene expression profiles. (karger.com)
  • The ectopic expression of human papilloma virus (HPV) E6/E7 gene has successfully been employed to establish these cell lines. (lu.se)
  • To induce differentiation and maturation of the immortalized cell lines, terminating the HPV-E6/E7 expression through a gene induction system has been believed to be essential. (lu.se)
  • Here, we report that erythroid cell lines established from human bone marrow using simple expression of HPV-E6/E7 are capable of normal erythroid differentiation, without turning gene expression off. (lu.se)
  • MicroRNAs are important post-transcriptional regulators of gene expression , with mutations in several microRNAs causal to specific human diseases . (bvsalud.org)
  • Multi-walled carbon nanotube -induced gene expression in the mouse lung: association with lung pathology. (cdc.gov)
  • Furthermore, 4 genes from these two sets of significant genes, coiled-coil domain containing-99 (Ccdc99), muscle segment homeobox gene-2 (Msx2), nitric oxide synthase-2 (Nos2), and wingless-type inhibitory factor-1 (Wif1), showed significant mRNA expression perturbations at both time points. (cdc.gov)
  • Altered gene expression and PTSD symptom dimensions in World Trade Center responders. (cdc.gov)
  • Analysis of gene expression from these individuals can help in identifying biomarkers of PTSD. (cdc.gov)
  • Using bulk RNA-sequencing from whole blood, we examined the association between gene expression and WTC-related PTSD symptom severity on (i) highest lifetime Clinician-Administered PTSD Scale (CAPS) score, (ii) past-month CAPS score, and (iii) PTSD symptom dimensions using a 5-factor model of re-experiencing, avoidance, emotional numbing, dysphoric arousal and anxious arousal symptoms. (cdc.gov)
  • An ERh gene expression profile was identified and was markedly different from the ERa signature. (lu.se)
  • Conclusion: Expression of ERh is an independent marker for favorable prognosis after adjuvant tamoxifen treatment in ERa-negative breast cancer patients and involves a gene expression program distinct from ERa. (lu.se)
  • The human genome is comprised of both non-coding DNA and coding regions, or genes. (sciencedaily.com)
  • We observed a downregulation in the expression of genes involved in host response, such as TNF signaling, IL-1β production, and phagosome formation in Mφ, and phosphatidylinositol signaling and TNF signaling in PMNs, being in line with the ability of the pathogen to survive within phagocytes. (frontiersin.org)
  • After many years of concerted effort to systematically analyze the expression of genes in all human cells and tissues, RIKEN and the FANTOM consortium publish the findings today in two landmark Nature reports, and 16 related articles in ten other scholarly journals (ref.1,2,3). (riken.jp)
  • The papers published in Nature describe maps of promoters and enhancers - short regions of DNA that influence the activity of genes - encoded in the human genome, and their activity across the vast wealth of human cell types and tissues of the human body. (riken.jp)
  • The FANTOM project (for Functional Annotation of the Mammalian genome) is a RIKEN initiative launched in 2000 to build a complete library of human genes using the capabilities offered by new, state-of-the-art cDNA technologies. (riken.jp)
  • In FANTOM5, we have for the first time systematically investigated exactly what genes are used in virtually all cell types across the human body, and the regions which determine where the genes are read from the genome," explains Dr. Alistair Forrest, scientific coordinator of FANTOM5. (riken.jp)
  • 687 genes differentiated tumor samples before and after treatment, among which 310 genes did not show the same differential expression in the placebo group or normal samples. (karger.com)
  • To identify key genes differentially expressed in the human retinal pigment epithelium (hRPE) following low-level West Nile virus (WNV) infection. (molvis.org)
  • RNA extracted from mock-infected and WNV-infected cells was assessed for differential expression of genes using Affymetrix microarray. (molvis.org)
  • Low-level WNV infection of hRPE cells induced expression of genes that are typically associated with the host cell response to virus infection. (molvis.org)
  • Bortoluzzi S, Alessi FD, Romualdi C, Danieli GA: Differential expression of genes coding for ribosomal proteins in different human tissues. (karger.com)
  • A widely accepted theory is that human growth, development and disease occurrence depends upon a complicated interaction between inherited genes and interactions with the environment. (cdc.gov)
  • At 7 and 56days post-exposure, a set of 7 genes and a set of 11 genes, respectively, showed differential expression in the lungs of mice exposed to MWCNT vs. the control group. (cdc.gov)
  • It was also found that the expression changes of these 4 overlapping genes at 7days post-exposure were attenuated at 56days post-exposure. (cdc.gov)
  • Berlin, December 23, 2022) - Uzbekistan's Information and Mass Communications Agency should withdraw a draft Information Code that, if adopted, would violate freedom of expression, including media freedom, Human Rights Watch said today. (hrw.org)
  • Uzbekistan's lawmakers shouldn't rush ahead with this draft law without considering the serious implications for freedom of expression and the nondiscrimination principle," said Mihra Rittmann , senior Central Asia researcher at Human Rights Watch. (hrw.org)
  • Uzbekistan is a party to the International Covenant on Civil and Political Rights (ICCPR), which among other rights guarantees the rights to freedom of expression, including the right to seek, receive, and impart information, and to be protected against discrimination. (hrw.org)
  • Uzbekistan partners should make it clear that Uzbekistan's stated reform agenda is incompatible with adoption of legislation that is discriminatory, violates freedom of expression, and is in breach of multiple obligations under the ICCPR. (hrw.org)
  • The topics of the visit were balancing security and human rights in the South East, freedom of expression and the administration of justice. (coe.int)
  • Long-standing problems concerning freedom of expression, arising from Turkish legislation and the practice of the judiciary, have also been severely exacerbated in this tense environment. (coe.int)
  • Mazen Darwish is the president of the Damascus-based Syrian Centre for Media and Freedom of Expression (SCM) , which he founded in 2004 to promote freedom of opinion and expression. (hrw.org)
  • General Comment 34 emphasises that freedom of expression and opinion are the foundation stone for a free and democratic society and a necessary condition for the promotion and protection of human rights. (humanrights.gov.au)
  • General Comment No. 25 deals with freedom of expression in the context of participation in public affairs and the right to vote. (humanrights.gov.au)
  • This participation is supported by ensuring freedom of expression, assembly and association. (humanrights.gov.au)
  • This includes freedom of expression. (humanrights.gov.au)
  • The Australian Constitution does not explicitly protect freedom of expression. (humanrights.gov.au)
  • This Seminar is a first step to identify synergies between the work of the CoE and the ENNHRI in the promotion and protection of the freedom of expression. (coe.int)
  • It was exploratory in nature and, with safety of journalists as a starting point, also focused on other aspects of freedom of expression. (coe.int)
  • when a State party imposes restrictions on the exercise of freedom of expression, these may not put in jeopardy the right itself. (humanrights.gov.au)
  • Given the fundamental nature of this right, international human rights bodies have scrutinised with great care any limitations on freedom of expression, including the introduction of regulatory schemes for media. (humanrights.gov.au)
  • A law may not confer unfettered discretion for the restriction of freedom of expression on those charged with its execution. (humanrights.gov.au)
  • Whether particular restrictions on freedom of expression which are designed to protect these rights are justifiable will depend on more specific consideration of the restrictions concerned and the circumstances. (humanrights.gov.au)
  • But aggressive campaigns to greatly exaggerate these imperfections, as part of the ongoing effort to delegitimize Israel facilitated by the soft-power of groups not subject to any democratic accountability, should not be assisted by a United Nations framework focusing on freedom of expression and freedom. (israelbehindthenews.com)
  • 3) Israel systematically protects the rights of its minority populations to freedom of expression and to protest. (israelbehindthenews.com)
  • 8) Therefore, NGO Monitor urges the Special Rapporteur to subject accusations from organizations and individuals regarding the state of freedom of expression in Israel to careful scrutiny and independent verification, and to avoid erasing the context of these allegations. (israelbehindthenews.com)
  • Our Human Rights team has an outstanding track record for defending freedom of expression and human rights. (howardkennedy.com)
  • Without freedom of expression there can be no democracy. (norway.no)
  • Freedom of expression and access to reliable information are important not only for each individual, but for the sustainable development of societies. (norway.no)
  • A commission mandated by my government, has reviewed the frameworks for freedom of expression in Norway. (norway.no)
  • Even if there is a high degree of freedom of expression, the commission reports challenges connected to for example hate speech and harassment. (norway.no)
  • Efforts are needed to ensure that freedom of expression is safeguarded as new forms of communication and new digital platforms are developed. (norway.no)
  • Data protection issues, surveillance technologies, online harassment, the spread of disinformation, and protection of the freedom of expression, are among these concerns. (norway.no)
  • Measures against hate speech must however not lead to restrictions in the freedom of expression that are contradictory to international standards. (norway.no)
  • Norway strongly supports the work of the OSCE, and in particular of the Representative on Freedom of the Media, to assist States in implementing their commitments to safeguard the freedom of expression and the right to receive and impart information without interference and regardless of frontiers. (norway.no)
  • In this podcast, they talk about hate speech, freedom of expression, the presence of neo Nazis at the political week of Almedalen in Sweden and many other places around the country. (lu.se)
  • Furthermore, IL-21 promotes differential expression of many cytokines including interleukins and chemokines. (intechopen.com)
  • The expression of normally spliced CYP3A5 mRNA in all human fetal liver samples varied 235-fold whereas CYP3A5 SV1 mRNA was only detected in fetal liver samples with at least one CYP3A5*3 allele. (aspetjournals.org)
  • NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
  • Over at Edge Armand Leroi was interviewed about human genetics & variation. (gnxp.com)
  • 156 (9.9%) were identified as human genomics/genetics publications. (cdc.gov)
  • All human genomics/genetics articles were coded according to topic and phase of translational research . (cdc.gov)
  • Vitronectin-integrin signaling, a major contributor to megakaryocyte maturation, was predominant in the yolk sac niche in HEMO and to human fetal samples. (newswise.com)
  • Upon differentiation, other ELLU clones shift from fetal to adult hemoglobin expression, giving rise to more mature cells. (lu.se)
  • Human epididymis protein 4 (HE4) was first identified in the epithelium of the distal epididymis and originally predicted to be a protease inhibitor involved in sperm maturation. (nature.com)
  • however, the expression in normal and malignant adult tissues has not been examined in detail. (nature.com)
  • An atlas of active enhancers across human cell types and tissues. (riken.jp)
  • We established the human embryonic organoid (HEMO) from expanded potential stem cells and achieved both embryonic and extraembryonic tissues in the same organoid. (newswise.com)
  • In contrast, the developmental expression of CYP3A5 is less well understood due to polymorphic expression of the enzyme in human tissues as a result of the prevalence of the CYP3A5*3 allele, which leads to alternative splicing. (aspetjournals.org)
  • In the present study, MDR1 P-gp was immunodetected by Western blot analysis in 60 human brain tumors, including meningiomas, schwannomas, low-grade gliomas (astrocytomas, pilocytic astrocytomas) and high-grade gliomas (anaplastic astrocytomas, glioblastomas and anaplastic oligodendrogliomas). (nih.gov)
  • These results indicate that the majority of primary brain tumors express MDR1 P-gp and that its high expression levels in meningiomas may be a marker for this type of brain tumor. (nih.gov)
  • This study confirms that alterations in the expression of exosomal miRNAs can promote osteogenic differentiation of ADSCs, which also provides the foundation for further research on the regulatory functions of exosomal miRNAs in the context of ADSC osteogenesis. (hindawi.com)
  • Signature MicroRNA expression patterns identified in humans with 22q11.2 deletion/DiGeorge syndrome. (bvsalud.org)
  • We characterized the microRNA expression patterns in the peripheral blood of patients with 22q11.2 deletion syndrome (n=31) compared to normal controls (n=22). (bvsalud.org)
  • 22q11.2 deletion syndrome cohort exhibited microRNA expression hyper-variability and group dysregulation. (bvsalud.org)
  • In summary, microRNA profiling of chromosome 22q11.2 deletion syndrome /DiGeorge patients revealed a signature microRNA expression pattern distinct from normal controls with clinical relevance . (bvsalud.org)
  • Human rights abuses are happening right now - start a monthly gift today. (hrw.org)
  • As crisis engulfed Syria in 2011, SCM and its staff worked to document serious and widespread human rights abuses with a view to contributing to a process leading to truth, justice, and reconciliation. (hrw.org)
  • Hamburg, Germany-based photographer Ralph Hargarten is behind this intriguing new series called A Dog's Life where he's shot portraits of dogs with facial expressions we often attribute to humans. (mymodernmet.com)
  • We are looking for a Blender artist to add shape keys to an existing 3D character for controlling facial expressions. (blenderartists.org)
  • Discriminatory or hateful expressions that are not, and should not be, prohibited, may nevertheless be harmful. (norway.no)
  • Regional and cellular dystrophin distribution was evaluated in both human and rat hippocampi and in rat cerebellar tissue by immunofluorescent colocalization with neuronal (NeuN and calbindin) and glial (GFAP) markers. (frontiersin.org)
  • Brain is the most important tissue in human speciation. (karger.com)
  • Tissue tropism and pathogenesis of influenza A virus subtype H5N1 disease in humans is not well defined. (cdc.gov)
  • The tissue tropism of the virus in humans has also not been clearly established by immunohistochemical analyses ( 10 , 11 ). (cdc.gov)
  • These chemicals do not break down in the body quickly, and they are stored in fatty tissue of animals and humans. (cdc.gov)
  • 6) In contrast, the history of reporting by UN frameworks on human rights in Israel has been characterized by biased mandates, false and unverifiable allegations, double standards, and hypocrisy - from Jenin (2002) through Goldstone (2009), as well as reports by special rapporteurs Jean Ziegler, John Dugard, and Richard Falk. (israelbehindthenews.com)
  • Explore the big challenges, opportunities, debates and frameworks for business and human rights. (business-humanrights.org)
  • The expression of telomerase, the enzyme that synthesizes telomeric DNA de novo , is suppressed in normal somatic human cells but is reactivated during tumorigenesis. (nature.com)
  • To clone a human CTR (hCTR), a BIN-67 cDNA library was screened using a cDNA probe from a porcine renal CTR (pCTR) that we recently cloned. (jci.org)
  • Interleukin-21 (IL-21) was first identified in 2000 through screening of a cDNA library from CD3+ human T cells [ 1 ]. (intechopen.com)
  • This report summarizes the epidemiology of human papillomavirus (HPV) and associated diseases, describes the licensed HPV vaccines, provides updated data from clinical trials and postlicensure safety studies, and compiles recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) for use of HPV vaccines. (cdc.gov)
  • Since 2011, OGPPH staff have assembled and curated an online, searchable database of CDC/ATSDR publications in human and pathogen genomics. (cdc.gov)
  • The Council of Europe and the European Network of National Human Rights Institutions (ENNHRI) organised a high level seminar as a follow-up activity to the SG's report on the State of democracy, human rights and the rule of law in Europe 2015. (coe.int)
  • Technologies have led to unprecedented human progress, but this digital era has also brought with it new challenges in protecting human rights and democracy. (norway.no)
  • Chronic exposure of humans to high level natural background radiation leads to robust expression of protective stress response proteins. (ncbs.res.in)
  • The substantial interindividual variability that remains even after stratification for CYP3A5 genotype suggests that factors such as environmental exposure and epigenetic alterations act in addition to genetic variation to contribute to the variability of CYP3A5 expression in human prenatal liver. (aspetjournals.org)
  • These theories may help guide future studies to explore whether inheritance of epigenetic modifications due to endocrine disruption exposure is possible in humans. (cdc.gov)
  • The immunohistochemical results showed prominent expression of CD44 in 13 of the patients and CD117 in 9 of the patients with new blister formation. (who.int)
  • Hippocampal full-length dystrophin (Dp427) levels are upregulated in human TLE, but not in AK rats, possibly indicating a compensatory mechanism in the chronic epileptic human brain. (frontiersin.org)
  • Expression of major histocompatibility antigens in human chronic pancreatitis. (bmj.com)
  • As expression of major histocompatibility (MHC) antigens is a prerequisite for organ specific autoimmunity, the expression of HLA class I (beta 2-microglobulin) and class II (HLA-DR) determinants have been analysed, together with the presence of T-lymphocytes, in 93 patients (64 men and 29 women, mean age 40.6 years) having an operation for chronic pancreatitis. (bmj.com)
  • No MHC expression was identified in 10 histologically normal pancreatic control specimens or in four cases of chronic pancreatitis secondary to obstruction by neuroendocrine tumours within the head of the pancreas. (bmj.com)
  • MHC determinant expression was not found in 10 cases (11%) of chronic pancreatitis. (bmj.com)
  • Aberrant MHC expression by exocrine pancreatic epithelial cells occurring in the presence of an appreciable T-cell infiltration confirmed that the appropriate cellular conditions were present for cell mediated cytotoxicity to contribute to the pathogenesis of chronic pancreatitis. (bmj.com)
  • A promoter level mammalian expression atlas. (riken.jp)
  • Bortoluzzi S, Alessi FD, Romualdi C, Danieli GA: The human adult skeletal muscle transcriptional profile reconstructed by a novel computational approach. (karger.com)
  • Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line. (jci.org)
  • To guide implementation, it is important to assess the current landscape of human genomics work at CDC and ATSDR (Agency for Toxic Substances and Disease Registry). (cdc.gov)
  • GPHPD was screened for CDC/ATSDR-authored publications about human genomics, including articles that assessed non-human genomes (e.g., pathogens, vectors). (cdc.gov)
  • We aimed to determine the significance of detecting expression of some antigens that might be pivotal to the process, namely CD44 and CD117, in patients with active pemphigus vulgaris. (who.int)
  • Her interests are directed towards understanding the fidelity of human DNA polymerases in addition to studying proteins involved in mismatch repair processes. (nih.gov)
  • Several proteins involved in diverse biological processes such as DNA repair, RNA processing, chromatin modifications and cytoskeletal organization showed distinct expression in HLNRA individuals, suggestive of both recovery and adaptation to low dose radiation. (ncbs.res.in)
  • Researchers recently discovered a novel mechanism that works over an extensive genomic distance and controls the expression of human growth hormone (hGH) in the pituitary gland. (sciencedaily.com)
  • Researchers at the University of Pennsylvania School of Medicine recently discovered a novel mechanism that works over an extensive genomic distance and controls the expression of human growth hormone (hGH) in the pituitary gland. (sciencedaily.com)
  • Most articles (n=1,348, or 85.8%) pertained to non-human genomic publications. (cdc.gov)
  • Taken together, this study provides for the first time an in-depth analysis of the transcriptomic alterations that take place in human phagocytes upon infection, and in peripheral blood immune populations during active disease. (frontiersin.org)
  • We performed quantitative discovery proteomics based on multiplexed isobaric tags (iTRAQ) coupled with LC-MS/MS on human peripheral blood mononuclear cells from HLNRA individuals. (ncbs.res.in)
  • They have insisted that States demonstrate convincingly the need for measures which prevent or restrict the operation of a free and independent media, and have been especially concerned about content-based restrictions and restrictions which might inhibit the expression of views that contribute to public and political debate. (humanrights.gov.au)
  • However, adenocarcinomas of the lung, and occasional breast, transitional cell and pancreatic carcinomas had moderate or high levels of HE4 expression. (nature.com)
  • However, limited previous data from human autopsies have not shown evidence of virus dissemination beyond the lung. (cdc.gov)
  • In contrast to disseminated infection documented in other mammals and birds, H5N1 viral replication in humans may be restricted to the lung and intestine, and the major site of H5N1 viral replication in the lung is the pneumocyte. (cdc.gov)
  • Single-cell level characterization of embryonic development is a major benchmark of human developmental biology. (newswise.com)
  • Members of the cytochrome P450 3A (CYP3A) subfamily of drug metabolizing enzymes exhibit developmental changes in expression in human liver characterized by a transition between CYP3A7 and CYP3A4 over the first few years of life. (aspetjournals.org)
  • Humans are complex multicellular organisms composed of at least 400 distinct cell types. (riken.jp)
  • Alongside its core work providing a platform for Human Rights advocates, the Resource Centre runs several focused programme areas and regularly releases briefings and reports on areas of particular interest. (business-humanrights.org)
  • Uzbekistan's Information and Mass Communications Agency should withdraw the bill for further amendments and invite independent media and information law experts to review the draft and provide expert analysis, Human Rights Watch said. (hrw.org)
  • Analysis of the primary protein structure of the human serotonin1B (5-HT1B) receptor reveals consensus sites for phosphorylation and a putative site for palmitoylation. (nih.gov)
  • Overall, our study advances the spatiotemporal analysis of human embryonic development in stem-cell-derived organoids. (newswise.com)
  • Respect for human rights has deteriorated at an alarming speed in recent months in the context of Turkey's fight against terrorism" said Nils Muižnieks, the Council of Europe Commissioner for Human Rights at the end of a nine- day visit to Istanbul, Diyarbakir and Ankara. (coe.int)
  • Disclaimer: Business & Human Rights Resource Centre and its collaborative partners take no position on the diverse views presented in linked material within the database, nor can we guarantee the factual accuracy of all the articles and reports we make available. (business-humanrights.org)
  • Business & Human Rights Resource Centre Registered Charity in England & Wales no. 1096664, 501(c)(3) non-profit organization in USA and registered charitable association (e.V.) in Germany (VR 38088 B). (business-humanrights.org)
  • A local monazite-rich high level natural radiation area (HLNRA) in the state of Kerala on the south-west coast of Indian subcontinent show radiation doses extending from ≤ 1 to ≥ 45 mGy/y and thus, serve as a model resource to understand low dose mechanisms directly on healthy humans. (ncbs.res.in)
  • The two-week time frame for public discussion of this far-reaching law does not give the public or media and information law experts adequate time to engage properly and ensure that the law will not adversely affect the rights of journalists, bloggers, others who work in the information sphere, including human rights activists, and the public at large, Human Rights Watch said. (hrw.org)
  • In 2004, it caused widespread disease in poultry in Asia ( 4 ) and led to human disease in Thailand and Vietnam, with reported fatality rates of 66% and 80%, respectively ( 5 , 6 ). (cdc.gov)
  • In this context, allegations of human rights violations are part of political or soft-power warfare that accompanies the hard-power attacks and violence. (israelbehindthenews.com)
  • This page therefore provides general information on the link between human rights and WHO FCTC implementation, in the context of defending legal challenges to tobacco control measures. (who.int)
  • Howard Kennedy's human rights practice is focused on high-end and novel work. (howardkennedy.com)
  • Newborn Screening is perhaps the most classic example of established public health applications of human genomics in practice, and accordingly, this topic had the highest proportion (86%) of late-phase studies (T2-T4). (cdc.gov)
  • There are also significant commonalities between human rights principles at the national level. (who.int)
  • Human rights are based on the principles of dignity, equality and mutual respect, which are shared across cultures, religions and philosophies. (who.int)
  • It explicitly references international human rights treaties and instruments and enshrines human rights principles within its text. (who.int)
  • The Information and Mass Communications Agency should ensure that any restrictions on freedom of information enshrined in the draft code are strictly limited to the extent that is necessary and proportionate, and only for legitimate purposes, as provided for under international human rights law. (hrw.org)
  • With the emergence of a second wave of disease outbreaks in poultry in Thailand, Vietnam, and Indonesia, this disease poses a global threat to human health ( 4 ). (cdc.gov)