Humans bacterial killing. Medical search. Frequent questions

Do Macrophages & Bacteriovorus Protozoa/Amoeba Have Similar Mechanisms in Killing Bacteria? (medscape.com)
In each case biphasic killing of bacteria was observed after a lag phase, and a biexponential model of microbial death could be fitted to the data. (nih.gov)
It works by killing the bacteria that cause infection. (medlineplus.gov)
An experimental cholesterol-fighting drug can also strip staph bacteria of their golden color and make the microbes more susceptible to killing by the immune system. (nih.gov)
Most potential antibiotics aim to directly kill bacteria. (nih.gov)
Like humans, bacteria can become infected with viruses. (voanews.com)
Some of them slowly kill the bacteria they infect. (voanews.com)
The bacteria are transmitted from animals to humans by ingestion through infected food products, direct contact with an infected animal, or inhalation of aerosols. (medscape.com)
The method involves white blood cells of the immune system called macrophages that eat bacteria, and a group of compounds that are naturally produced in mice and humans called epoxyeicosatrienoic acids or EETs. (nih.gov)
Many of these bacteria are also deadly to humans. (nih.gov)
Humans and animals have natural defense systems that produce antibodies in the blood to combat bacteria and other harmful substances invading the body. (nih.gov)
SIVEXTRO is an oxazolidinone antibacterial indicated in adult and pediatric patients 12 years of age and older for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by designated susceptible bacteria. (nih.gov)
Bacteriophages selectively kill bacteria and present an alternative to antibiotics. (zhaw.ch)
Phages are viruses that can kill or neutralize specific bacteria while leaving non-target bacteria and human cells unharmed. (nih.gov)
Nanowerk News ) An international research team led by the Institute of Bioengineering and Nanotechnology (IBN) of the Agency for Science, Technology and Research (A*STAR) and IBM Research developed a synthetic molecule that can kill five deadly types of multidrug-resistant bacteria with limited, if any, side effects. (nanowerk.com)
To address this problem, Dr Yi Yan Yang from IBN brought together a multidisciplinary research team from the US, China and Singapore to develop a new class of antimicrobial polymers called guanidinium-functionalized polycarbonates with a unique killing mechanism that can target a broad range of multidrug-resistant bacteria. (nanowerk.com)
The polymer kills bacteria in the following way. (nanowerk.com)
Image on right showed that the cytoplasmic substances within the bacterial cell membrane have precipitated, killing the bacteria. (nanowerk.com)
Once the polymer finishes its job of killing the bacteria, it will be naturally degraded after three days and will not remain in the body. (nanowerk.com)
This therapy uses naturally-occurring viruses, called bacteriophages (phages) which infect and kill bacteria to treat bacterial infections. (akcchf.org)
Phage therapy has a long history of safe and effective use in humans and has the advantages that it can target drug resistance bacteria with few side effects. (akcchf.org)
In lab work done with mice and human blood, researchers found high doses of the vitamin increased the ability of immune cells to kill the bacteria by 1,000 times. (medicalnewstoday.com)
Although antibiotics are very effective against bacterial infections, an increasing number of bacteria types, especially Staphylococcus aureus , are becoming resistant to them, leaving fewer and fewer options for treatment. (medicalnewstoday.com)
Working on this problem led to finding that nicotinamide can "switch on" some of the disabled anti-microbial genes , giving immune cells greater capacity to kill infectious bacteria. (medicalnewstoday.com)
In this latest study, the team showed mice bred to be deficient in C/EBPε were severely affected by infection with S. aureus , and it was deficiency of the C/EBPε protein in their neutrophils (a type of white blood cell that kills and devours harmful bacteria), that was responsible. (medicalnewstoday.com)
Our findings suggest that C/EBPε is an important target to boost killing of bacteria by the innate immune system," conclude the authors. (medicalnewstoday.com)
For successful UTI treatment, we must predict how bacteria will evade killing by phage and identify the downstream consequences of phage resistance during bacterial infection. (nih.gov)
In our current study, we found that while phage-resistant bacteria quickly emerged in vitro , these bacteria were less capable of growing in human urine and colonizing the murine bladder. (nih.gov)
Instead of Killing Bacteria, Can We Just 'Turn Off' Its Ability To Cause Infections? (smithsonianmag.com)
We do already have some so-called antivirulence drugs that don't kill bacteria but make them harmless so that the body's immune system can clear them out without leaving any behind to become resistant to the drug. (smithsonianmag.com)
This is a really important challenge in medicine right now, because bacteria that are resistant to antibiotics kill 700,000 people a year worldwide . (smithsonianmag.com)
Bacteria regularly develop and deploy new antibiotics in a never-ending arms race to kill other bacterial species that compete for mutual resources. (phys.org)
Vaccine research at the time focused on using whole bacteria that had been killed or weakened. (nih.gov)
Using polysaccharide-based vaccines eliminated many of the side effects of killed-bacteria vaccines, while still producing ample amounts of antibody (molecules made by the immune system) in adults and older children to prevent disease. (nih.gov)
In vitro, rhu-pGSN rapidly improved lung macrophage uptake and killing of bacteria (Streptococcus pneumoniae, Escherichia coli, and Francisella tularensis). (nih.gov)
Through extensive use of synthetic biology, the team designed four bacterial viruses that use CRISPR technology to kill the unwanted bacteria precisely. (sciencedaily.com)
Along with killing the bad bacteria in his stomach, these antibiotics also wiped out the good bacteria. (losethebackpain.com)
The molecule, known as KKL-55, is one of a suite of recently identified molecules that interfere with a key bacterial mechanism known as trans -translation, essentially shutting down the ability of bacteria to grow. (emory.edu)
Cross-toxicity, or harmful effects on humans, is another key drawback of some of the drugs used in a last-ditch effort to kill antibiotic-resistant bacteria. (emory.edu)
This bacteria can cause a wide range of illnesses in humans ( 5 ). (healthline.com)
The findings, which are presented in the open access journal BMC Biology , suggest that the bacteria may potentially be used in future, to control roundworm infections in animals, plants, and, potentially, humans. (phys.org)
In the laboratory experiments, the worms remained on the bacterial lawns cultivated by the researchers and actively ingested the bacteria, which multiplied inside the worms' pharynx and digested them from the inside out. (phys.org)
The bacteria only lives in humans, not animals. (nih.gov)
In 1896, Germans Richard Pfeiffer and Wilhelm Kolle proved that inoculation with killed typhoid bacteria resulted in immunity. (nih.gov)
Food-grade antimicrobials are approved for use by the U.S. Department of Agriculture and the Food & Drug Administration as a very safe and effective way to kill or inhibit the growth of any potential bacteria and foodborne pathogens, like Salmonella . (nationalchickencouncil.org)
CPC is an antiseptic that kills bacteria and other microorganisms. (nationalchickencouncil.org)
A bacterial extract containing 95% TDA was effective against a range of human-pathogenic bacteria, including both Gram-negative and Gram-positive bacteria. (dtu.dk)
it kills bacteria and promotes inflammation (4). (bodyecology.com)
This bacterium is commonly found in soils and water, where bacteria are constantly under threat of being consumed by bacterial predators, e.g., protozoa. (edu.au)
To escape being killed, bacteria have evolved a suite of mechanisms that protect them from being consumed or digested. (edu.au)
The effects on bactericidal activity were evaluated by determining the ability of the macrophages to phagocytize or kill Staphylococcus-aureus bacteria. (cdc.gov)
These studies have led us to the discovery of a large class of ancient CDC relatives that have spread throughout the Bacteria kingdom and are present in many major species of the human microbiome. (hhs.gov)

This is often the case, since such pathogens and humans are genetically distant. (wikipedia.org)
We propose that when CFA arrives at the airway, it rapidly adsorbs AMPs and creates negative complexes, thereby decreasing the functional amount of AMPs capable of killing pathogens. (nih.gov)
Neutrophil extracellular traps, or NETs, are formed in response to microbial pathogens and have been shown to ensnare these pathogens and inactivate or kill them. (nih.gov)
Here you will find information on different pathogens in humans and animals. (ages.at)
Dramatic worldwide increase in antibiotic resistance to human pathogens is of great concern. (zhaw.ch)
We study the molecular basis of persistence of one of the deadliest bacterial pathogens, Mycobacterium tuberculosis (Mtb), which kills over a million people every year. (wadsworth.org)

Phage-resistant strains displayed several in vitro phenotypes, including alterations to adherence to and invasion of human bladder epithelial HTB-9 cells and increased biofilm formation in some isolates. (nih.gov)
Interestingly, these phage-resistant UPEC isolates demonstrated reduced growth in pooled human urine, which could be partially rescued by nutrient supplementation and were more sensitive to several outer membrane-targeting antibiotics than parental strains. (nih.gov)
Antibiotics no longer work on some strains of A. baumannii - and the World Health Organization recently ranked it as the greatest bacterial threat to human health . (smithsonianmag.com)
Gut bacterial strains have been discovered that boost immune cells that have cell-killing capacity and that can target cancer and protect against infection. (natureasia.com)
Possible underlying causes of recurrent canine pyoderma can be categorized as persistent underlying skin disease, bacterial hypersensitivity, immunodeficiency, resistant strains of Staphylococcus spp. (vin.com)
They found that the ancient Peruvian TB bacterium was most akin not to any human strain, but to strains that infect pinnipeds-seals and sea lions. (archaeology.org)
The researchers isolated two new bacterial strains-JUb129 and JUb275-from free-living roundworms found on a rotten apple in Paris, France, and a rotten fig in Bangalore, India. (phys.org)
In a pilot study of 24 sera and 5 MenB strains, we tested intrinsic killing and observed seventeen sera (71%) showed intrinsic killing against all strains. (nih.gov)
From analyzing the bacteria's various strains, scientists have been able to test their theories about how humans colonized Pacific islands 30,000 years ago. (livescience.com)
Inhibition of biofilm formationwas significant with the three bacterial strains. (ias.ac.in)

Bacteriophages are bacterial viruses that are attracting increasing attention worldwide as a promising alternative to conventional antibiotics. (zhaw.ch)
For more than a century, researchers have considered the potential use of phages as therapeutics, theorizing that mixtures of bacteriophages might be used on their own, or in conjunction with antibiotics, to treat bacterial infections-especially those resistant to antibiotics. (nih.gov)
Antibiotics are poisons that kill tiny bacterial organisms in tiny doses. (knowthecause.com)
Then antibiotics would become grossly overprescribed and perhaps be contributing to much human suffering. (knowthecause.com)
Antibiotics are fungal mycotoxins and as such, they are toxic to the brain, lungs, immune system and heart and every human tissue. (knowthecause.com)
During treatment, the veterinarians gave Dax antibiotics to fight the bacterial infection. (losethebackpain.com)

Here, we review bacterial and host factors, focusing on the role of neutrophils and their elastase, which contribute to the progression of pneumococcal pneumonia. (frontiersin.org)
5. Garenoxacin-induced increase of CD11b expression on human polymorphonuclear neutrophils does not affect phagocytosis and killing of Staphylococcus aureus. (nih.gov)
14. The in vitro effects of methotrexate on the phagocytosis and intracellular killing of Staphylococcus aureus by human neutrophils. (nih.gov)
In another experiment, they also found that vitamin B3 increased the activity of the gene, and selected bacterial targets, particularly in neutrophils. (medicalnewstoday.com)
And finally, in a mouse model, as well as in mouse and human blood cultures, they showed vitamin B3 "enhanced killing of S. aureus by up to 1,000 fold", but it had no effect when given to mice that were either deficient in C/EBPε or in mice depleted of neutrophils. (medicalnewstoday.com)
We also demonstrate that CodY repression of sae restrains production of secreted cytotoxins that kill human neutrophils. (nih.gov)
Transcriptional and post-transcriptional - the control of gene expression at the RNA level - processing regulates expression of human cathelicidin peptides, such as the active form LL37 released from neutrophils (2). (bodyecology.com)
The effects on chemotaxis was evaluated by measuring the ability of the macrophages to recruit human neutrophils using a blind well chemotaxis chamber technique. (cdc.gov)

An antimicrobial should not be confused with an "antibiotic," which is medicine used to treat bacterial infections in humans and animals. (nationalchickencouncil.org)

This bacterium is a leading cause of bacterial pneumonia, otitis media, meningitis, and septicemia, and is a major cause of morbidity and mortality worldwide. (frontiersin.org)
NIH scientists say the approach may be a novel way to treat pneumonia in humans. (nih.gov)
Researchers at the National Institutes of Health have discovered a therapy that targets host cells rather than bacterial cells in treating bacterial pneumonia in rodents. (nih.gov)
In a mouse model of primary pneumococcal pneumonia, recombinant human pGSN (rhu-pGSN) caused enhanced bacterial clearance, reduced acute inflammation, and improved survival. (nih.gov)
Prophylaxis with immunomodulators may be especially relevant for patients at risk for secondary bacterial pneumonia, e.g., after influenza. (nih.gov)
pGSN is a potential immunomodulator for improving lung host defense against primary and secondary bacterial pneumonia. (nih.gov)

Although I had study bacteriophages in gengeral in my microbiology class, I really did not understand how important bacteriophages may be to cure bacterial infections. (topdocumentaryfilms.com)
May bacteriophages evolve to kill human cells? (topdocumentaryfilms.com)

It has been reported that bacterial virulence factors directly damage human tissues or cause malfunctioning of the human immune system, resulting in an excessive inflammatory response. (frontiersin.org)
This human pathogen intercepts host cues and activates a transcriptional response via the S. aureus exoprotein expression (SaeR/SaeS [SaeR/S]) two-component system to secrete virulence factors critical for pathogenesis. (nih.gov)

Then, the polymer is transported across the bacterial cell membrane into the cytoplasm, where it causes precipitation of the cell contents (proteins and genes), resulting in cell death. (nanowerk.com)
So if we can create drugs that make these changes to bacterial proteins in this way, we could have a new way of stopping infections. (smithsonianmag.com)
Our findings reveal a strategy by which S. aureus delays the production of immune evasion and immune-cell-killing proteins until key nutrients are depleted. (nih.gov)

However, no bacteriaphage is strong enough to stop a galloping bacterial infection inside a human or animal. (voanews.com)

7. Bovine pulmonary alveolar macrophages: antemortem recovery and in vitro evaluation of bacterial phagocytosis and killing. (nih.gov)
rhu-pGSN failed to enhance bacterial killing by NOS3(-/-) macrophages in vitro or bacterial clearance in NOS3(-/-) mice in vivo. (nih.gov)
The effects of a bacterial endotoxin on the functional status of alveolar macrophages were studied in-vitro. (cdc.gov)

6. Interaction between human polymorphonuclear leucocytes and Staphylococcus aureus in the presence and absence of opsonins. (nih.gov)
11. Synergistic effect of cefepime on the phagocytic killing of Staphylococcus aureus by human polymorphonuclear leucocytes and the determination of this effect by means of nitrite production. (nih.gov)
12. Effects of selenium-vitamin E injection on bovine polymorphonucleated leukocytes phagocytosis and killing of Staphylococcus aureus. (nih.gov)
17. Clindamycin at subinhibitory concentrations enhances antibody- and complement-dependent phagocytosis by human polymorphonuclear leukocytes of Staphylococcus aureus. (nih.gov)
Mutation of this gene is responsible for neutrophil-specific granule deficiency in humans, a condition that confers susceptibility to Staphylococcus aureus infection. (medicalnewstoday.com)
Staphylococcus aureus subverts innate defenses during infection in part by killing host immune cells to exacerbate disease. (nih.gov)
TDA was bactericidal against Salmonella enterica serovar Typhimurium SL1344 and Staphylococcus aureus NCTC 12493 and killed both growing and nongrowing cells. (dtu.dk)

Researchers have developed a new antibiotic that not only kills the anthrax strain used in last October's U.S. attacks but also could be used to rapidly detect areas, such as buildings, suspected of anthrax contamination. (voanews.com)
Because each bacterium has a bacteriaphage, the scientists say they could use the same approach they used to develop an antibiotic against anthrax to target other bacterial infections, including strep and menningitis. (voanews.com)
The discovery opens the door to a new arsenal of tools for dealing with antibiotic-resistant bacterial infections, such as those caused by methicillin-resistant S. aureus or MRSA , that have killed thousands of people around the world. (medicalnewstoday.com)
We recently studied a possible way to affect bacterial epigenetics that might be able to stop infections without using antibiotic drugs. (smithsonianmag.com)
Treatment of mice with pGSN challenged with pneumococci on postinfluenza day 7 (the peak of enhanced susceptibility to secondary infection) caused a ∼15-fold improvement in bacterial clearance, reduced acute neutrophilic inflammation, and markedly improved survival, even without antibiotic therapy. (nih.gov)
Scientists have shown how a molecule with broad-spectrum antibiotic activity works by disabling a process vital to bacterial growth without affecting the normal functioning of human cells. (emory.edu)
If we use a conventional antibiotic which kills the Pseudomonas, there will always be some survivors, some of which may develop antibiotic resistance. (sciencecodex.com)

however, phage-bacterial interactions within the urinary environment are poorly defined. (nih.gov)
In both bacteriologic medium and pooled human urine, we identified phage resistance arising within the first 6 to 8 h of coincubation. (nih.gov)
These results have implications for developing cocktails of phage with multiple different bacterial targets, of which each is evaded only at the cost of bacterial fitness. (nih.gov)
A new paper in Nature Biotechnology titled 'Engineered phage with antibacterial CRISPR-Cas selectively reduce E. coli burden in mice' describes the development of the drug candidate to a stage where it is ready for tests on humans. (sciencedaily.com)

Where we mix the enzyme the [anthrax] bacterium in a test tube and showed that we could kill millions of organisms in a very short period of time,' he said. (voanews.com)
MICROBES -tiny organisms too small to be seen with the naked eye-have altered human history. (nih.gov)
All organisms, from microbes to humans, are governed by the genetic code embedded in their DNA. (nih.gov)
1. Antibacterial - One of the main benefits of tea tree oil is its ability to act as an antibacterial disinfectant for cuts and abrasions of the human body, but it is also known for this because it kills all three infection organisms: bacterial, viral and fungal. (massage-education.com)

Leptospiral species, including the heat-killed and nonpathogenic saprophytic strain, induced NET formation as measured both by visual examination of cells adhered to microscope slides and by assays for quantification of extracellular DNA and increased myeloperoxidase accumulation in cultured cells. (nih.gov)
In contrast with earlier studies with human cells, bovine PMNs, while activated by the presence of Leptospira , are not effective in killing the Leptospira . (nih.gov)
The phages in the cocktail are highly specific and do not attack human cells. (nih.gov)
It is biodegradable and non-toxic to human cells. (nanowerk.com)
In humans, mitochondrial DNA spans about 16,500 DNA building blocks (base pairs), representing a small fraction of the total DNA in cells. (nih.gov)
Bacterial cells have their own version of histone known as HU, which organizes their DNA and is involved in making all its functions work. (smithsonianmag.com)
or 2) in vitro comparison of immune profiles in primary human cells and primary cells from dirty mice. (nih.gov)
Microorganisms in the human gut can affect immune-system cells. (natureasia.com)
Researchers engineer a synthetic circuit that promotes bacterial invasion of tumour cells. (wikipedia.org)
Human cells have efficient ways to test mRNAs and ultimately remove the defective ones. (emory.edu)
Bacterial cells, however, have no nucleus or organized center for quality control. (emory.edu)
Because of their antioxidant content, test-tube studies show that both black and white truffles may even help kill cancer cells and reduce inflammation ( 4 ). (healthline.com)

Neisseria meningitidis is a major cause of bacterial meningitis and remains a major public health problem. (nih.gov)

Recent studies have demonstrated that neutrophil accumulation, which is generally considered to play a critical role in host defense during bacterial infections, can significantly contribute to lung injury and immune subversion, leading to pneumococcal invasion of the bloodstream. (frontiersin.org)

Once we verify the link between specific epigenetic changes and bacterial infection, we can begin looking for substances that alter bacteria's epigenetics in this way to make it less harmful. (smithsonianmag.com)

Many drug molecules are enzyme inhibitors that inhibit an aberrant human enzyme or an enzyme critical for the survival of a pathogen such as a virus, bacterium or parasite. (wikipedia.org)
In the 1970s, scientists inserted a human gene into the genetic material of a common bacterium. (nih.gov)
P. aeruginosa , a serious and sometimes deadly bacterium frequently acquired in healthcare settings, is the most common bacterial cause of CF exacerbations. (nih.gov)
It contains a cocktail of four bacteriophage species that naturally infect P. aeruginosa and take over its cellular processes, killing the bacterium in the process. (nih.gov)
Our study looked at the bacterium Acinetobacter baumannii , which is a major cause of the infections people can catch in hospitals and which kills up to 70 percent of people who are infected with it . (smithsonianmag.com)
These worms were killed by the bacterium in the same way as C. elegans . (phys.org)
Many people who carry the bacterium won't ever experience any symptoms of the infection, but it's the culprit behind most ulcers and many cases of stomach cancer - and it hid, unidentified, inside human stomachs for thousands of years. (livescience.com)

If those headlines above were treated with anti-fungal drugs, instead of anti-bacterial drugs, I doubt that they would be headlines at all. (knowthecause.com)
In the third aim we plan to study the mechanism of bacterial killing by a novel class of anti-bacterial toxins that are produced by a few species of the Provote/la and Bacteroides found in the oral and intestinal microbiome of humans. (hhs.gov)
Finally, these studies will reveal the molecular mechanism of a unique class of anti-bacterial toxins, which could potentially be used in therapies for infections. (hhs.gov)

Additionally, high-quality studies should be conducted to determine how the antibacterial properties of truffles may affect these bacterial infections in humans. (healthline.com)

According to the UK Review on Antimicrobial Resistance, superbugs kill around 700,000 people worldwide each year. (nanowerk.com)
The spread of antimicrobial resistance is a major threat to modern medicine, for both humans and animals. (akcchf.org)
Antimicrobial resistance in S. pseudintermedius is making infections more difficult to treat which is affecting dog welfare and might pose a threat to humans too. (akcchf.org)

In a preliminary experiment, the researchers treated staph-infected mice with BPH-652 and found that bacterial levels dropped significantly compared to untreated mice. (nih.gov)
The polymers eliminated the bacterial infections in both groups of mice with negligible toxicity. (nanowerk.com)
Dr Yi Yan Yang, Group Leader at IBN said, "We have demonstrated the first example of a biodegradable synthetic macromolecule with broad-spectrum antimicrobial activity in mice, unique killing mechanism and no toxicity. (nanowerk.com)
This Notice of Special Interest (NOSI) solicits research on immunologic characterization of mice with diverse microbial exposures (commonly referred to as "dirty mice") to determine their usefulness as research tools to advance understanding of human immune function in homeostasis and in response to infectious or immune-mediated diseases. (nih.gov)
However, despite the utility of mice in immunological and vaccine research, there are multiple differences in immune responses between laboratory mice and humans that limit the translatability of mouse findings to humans. (nih.gov)
and normobiotic mice, which are generated via cecal ligation and puncture, implantation of heat-killed cecal contents, or implantation of cecal tissue. (nih.gov)
Recent studies comparing dirty mice and mice maintained under standard specific pathogen-free (SPF) conditions suggest that the presence of a diverse microbiome may account for some of the differences in immune responses between laboratory mice and humans, since microbial exposure significantly influences development and function of both the innate and the adaptive arms of the immune system. (nih.gov)
Additionally, SPF mice poorly recapitulate mature human immune responses and exhibit responses more like human neonates. (nih.gov)
In contrast, dirty mice react to immune stimuli more like human adults, making them a potentially better research tool. (nih.gov)

The blacklegged tick ( Ixodes scapularis ) is a frequent human-biter and vector of viral, bacterial, and parasitic agents causing human illness, including Lyme disease ( 1 ). (cdc.gov)
Unregulated minimum risk 25(b) exempt products are proliferating in the marketplace but there is concern about their effectiveness to kill and repel ticks, as expressed in the 2020 report by the Tick Biology, Ecology, and Control subcommittee of the Tick-Borne Disease Working Group established by the US Department of Health and Human Services ( 6 ). (cdc.gov)
It is also theoretically possible to 'eliminate' a disease in humans while the microbe remains at large, as in the case of neonatal tetanus, for which the World Health Organization (WHO) in 1989 declared a goal of global elimination by 1995. (cdc.gov)
NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
Citrus greening is a bacterial disease that reduces production and can kill trees. (southeastagnet.com)
The disease specifically attacks citrus plants and presents no threat to humans or animals. (southeastagnet.com)
Human immune deficiency virus is a life threatening immune deficiency disease causing virus. (omicsonline.org)
IMPORTANCE Bacterial mechanisms that mediate the switch from a commensal to pathogenic lifestyle are among the biggest unanswered questions in infectious disease research. (nih.gov)
Tuberculosis (TB), a bacterial infection that kills more than a million people each year and sickens many more, has a short but complicated natural history involving humans, migration around the world, and animals that also carry the disease. (archaeology.org)
Typhoid fever is a bacterial disease caused by Salmonella typhi . (nih.gov)
Individuals whose sera lacked bactericidal killing were at risk for developing disease. (nih.gov)

FPCN containing specific antigen are capable to stimulate T-cell very well to kill the viruses. (omicsonline.org)
How can viruses pathogenic to humans can be destroyed? (topdocumentaryfilms.com)

This is a serious threat to human health. (zhaw.ch)

Charpentier and Doudna labs publish in Science the programming of CRISPR-Cas9 bacterial immunity for targeting DNA cleavage. (wikipedia.org)

The opportunistic pathogen Pseudomonas aeruginosa is ubiquitous in the environment, and in humans, it is capable of causing acute or chronic infections. (edu.au)
IMPORTANCE Pseudomonas aeruginosa is an opportunistic pathogen that causes both acute infections in plants and animals, including humans, and chronic infections in immunocompromised and cystic fibrosis patients. (edu.au)

Cytoplasmic leakage from each bacterial strain was also demonstrated on account of NP treatment. (ias.ac.in)

Nowadays Nano-Medicine is a promising field for manufacturing vaccines for various bacterial and viral diseases. (omicsonline.org)
Dr. John B. Robbins and colleagues also worked on typhoid vaccines, promoting the assessment of the Vi capsular polysaccharide for protection of humans against typhoid. (nih.gov)

The researchers then tested different drugs that act on the human cholesterol enzyme. (nih.gov)
The researchers found that in human blood, vitamin B3 was able to wipe out the staph infection in a few hours. (medicalnewstoday.com)
Researchers publish in Science the first synthetic bacterial genome, called M. mycoides JCVI-syn1.0. (wikipedia.org)

Dr Alan Smyth of the University's School of Human Development, who is leading the project, said: "The garlic components inhibit a bacterial communication system called quorum sensing (QS). (sciencecodex.com)

This research was published in Nature Medicine in August, and was selected as one of 2020's top advances in genomic medicine by The American Journal of Human Genetics . (nih.gov)

4. Influence of modified natural and synthetic surfactant preparations on bacterial killing by polymorphonuclear leucocytes. (nih.gov)

First, the polymer binds specifically to the bacterial cell. (nanowerk.com)

Some nematodes, such as hookworms, also infect humans. (phys.org)

a bacterial infection that may cause serious symptoms) in patients with human immunodeficiency virus (HIV) infection. (medlineplus.gov)

Production of O2- was significantly increased by the endotoxin or bacterial extract in a dose dependent manner. (cdc.gov)

This is an entirely new approach that seems to work in animals, and now we need to take the next step to explore if it will work in humans," said Oldfield. (nih.gov)
4] Humans have only a limited risk from wild animals, mainly because of lack of proximity or intimate contact and infrequent use of milk and meat products from these animals. (medscape.com)
We evaluate hazards along the food chain to assess the associated outgoing risk to humans, animals and plants. (ages.at)
Only the female mosquito feeds on the blood of humans or other animals. (capcvet.org)
Only female mosquitoes are found on or around humans and other animals. (capcvet.org)

Mtb is the causative agent of human tuberculosis (TB), which has inflicted humans since the prehistoric era. (wadsworth.org)

They puncture and destroy bacterial membranes, reducing the chance of bacterial drug resistance. (bodyecology.com)

For the first time, scientists have calculated the global impact of human activity on animal movement, revealing widespread impacts that threaten species survival and biodiversity. (phys.org)
This study describes a newly discovered bacterial species , called Chryseobacterium nematophagum - or golden death bacillus-that effectively kills a wide range of important nematode parasites. (phys.org)
To investigate which genes might be involved in conferring the nematode-killing ability of C. nematophagum , the authors compared the genomes of the two newly identified species to those of five other Chryseobacterium species that are not known for killing nematodes. (phys.org)

These results show that drugs can also be designed to weaken bacterial defenses and make them more vulnerable to the immune system. (nih.gov)

However, additional studies are needed to evaluate how truffles may impact cancer growth in humans when eaten rather than in concentrated extract form. (healthline.com)

This finding was reported in the scientific journal Nature Communications ( 'A Macromolecular Approach to Eradicate Multidrug Resistant Bacterial Infections While Mitigating Drug Resistance Onset' ). (nanowerk.com)
The CDC estimates that at least 2.8 million antimicrobial-resistant infections continue to occur in the United States each year, killing more than 35,000 people. (emory.edu)

This product is made from S. aureus of human origin. (vin.com)

Still, more research is needed to understand how eating normal amounts of truffles may influence levels of inflammation in humans. (healthline.com)

These results provide a novel translational insight into an early mechanism for how ambient PM increases the susceptibility of the airways to bacterial infection. (nih.gov)

Thus, predation by protozoa and long-term colonization of the human host may represent similar environments that select for similar losses of gene function. (edu.au)

when you are trying to come up with a drug to counteract a specific agent, you want to kill off the microbes but not harm the patient. (flashcardmachine.com)

Since anti-pathogen inhibitors generally target only one enzyme, such drugs are highly specific and generally produce few side effects in humans, provided that no analogous enzyme is found in humans. (wikipedia.org)
A low concentration of the enzyme inhibitor reduces the risk for liver and kidney damage and other adverse drug reactions in humans. (wikipedia.org)
In collaboration with colleagues in Taiwan, the scientists confirmed that a bacterial enzyme needed to create the gold pigment had a structure that was similar to a human enzyme involved in cholesterol production. (nih.gov)
Structural studies also showed that several cholesterol-lowering drugs could bind tightly to the bacterial enzyme. (nih.gov)
Mr. Fischetti thinks the drug would work as well in humans and with virtually no side effects, since the enzyme is specifically targeted to attack the anthrax infection. (voanews.com)
The QS molecules also switch on bacterial weapons such as 'elastase', an enzyme which breaks down elastic tissue in the lung. (sciencecodex.com)

Streptococcus pneumoniae , also known as pneumococcus, is a Gram-positive diplococcus and a major human pathogen. (frontiersin.org)
Aug 10, 2011 (CIDRAP News) - An investigation into the origins of Minnesota's first human anthrax case in many years is focusing on where the patient might have been exposed to the deadly pathogen, Minnesota State Epidemiologist Dr. Ruth Lynfield said today. (blogspot.com)

There are already several molecules targeting human epigenetics in a similar way under preclinical development or in clinical trials . (smithsonianmag.com)

Bacterial drug resistance can lead to serious consequences. (bodyecology.com)

While Gila Monsters can inflict serious injury , their bite is not often deadly to humans. (a-z-animals.com)

This project has a team of veterinarians and scientists working together to isolate and characterize phages that kill S. pseudintermedius which may contribute to the development of new, exciting treatments to benefit dog health and wellbeing. (akcchf.org)
Scientists at ETH Zurich report the creation of the first bacterial genome , named Caulobacter ethensis-2.0 , made entirely by a computer, although a related viable form of C. ethensis-2.0 does not yet exist. (wikipedia.org)

The current research for treating bacterial infections rounds out our ability to someday treat a spectrum of infectious diseases with a single, new type of mechanism without the onset of resistance. (nanowerk.com)
This mechanism is vital to the proper functioning of the bacterial ribosome. (emory.edu)

Strategies to prevent human tick bites include broadcast of pesticide products (toxicants) to kill host-seeking ticks in the environment and potentially reduce the likelihood of encountering ticks, as well as use of repellent products applied to skin or clothing to reduce the chance of a tick encounter leading to a bite ( 2 ). (cdc.gov)

We found increased bacterial survival in CFA-exposed airway explants, ASL, and AMPs. (nih.gov)

Even other mammals, including cats and dogs, can transfer these fungal infections to humans. (medicinenet.com)

Hib is a commonly occurring bacterial infection. (nih.gov)

Anatomy32

Organisms34

Diseases18

Chemicals and Drugs83

Analytical, Diagnostic and Therapeutic Techniques and Equipment27

Phenomena and Processes62

Anthropology, Education, Sociology and Social Phenomena1

Information Science4

Health Care5

Bacteria52

Pathogens6

Strains10

Antibiotics6

Neutrophils8

Treat bacterial infections1

Pneumonia6

Bacteriophages2

Virulence2

Proteins3

Galloping bacterial infection1

Macrophages3

Staphylococcus7

Antibiotic7

Phage4

Organisms4

Cells12

Cause of bacterial1

Host defense1

Substances1

Bacterium7

Anti-bacterial3

Infections in humans1

Antimicrobial Resistance3

Mice9

Disease11

Viruses2

Threat1

Immunity1

Acute2

Cytoplasmic1

Vaccines2

Researchers3

Inhibit1

Genetics1

Synthetic1

Binds1

Infect humans1

Immunodeficiency1

Significantly1

Animals5

Tuberculosis1

Puncture1

Species3

Defenses1

Extract1

Resistant2

Aureus1

Inflammation1

Susceptibility1

Protozoa1

Microbes1

Enzyme6

Pathogen2

Molecules1

Drug resistance1

Deadly to humans1

Scientists2

Mechanism2

Potentially1

Survival1

Fungal infections1

Commonly1