• However, regardless of how strongly you support life, you may unknowingly be cooperating in aborted fetal cell research by purchasing products that use aborted fetuses either in the product itself or in its development. (hli.org)
  • Associated with new knowledge on the human genome, it could be used to facilitate genotype selection and encourage social and parental intolerance of disability or, potentially, perceived genetic defects. (who.int)
  • Last month, two research groups independently published proof that the fetal genotype - the genetic status at a given locus - can be derived for thousands of sites from samples of fetal DNA with just a 10-millilitre blood draw from a pregnant woman 2 , 3 . (nature.com)
  • 2000. Breast adipose tissue concentrations of polychlorinated biphenyls and other organochlorines and breast cancer risk. (cdc.gov)
  • Downregulated adipose tissue expression of browning genes with increased environmental temperatures. (medscape.com)
  • that an object of investigation cannot be accessed outside of human conceptual frameworks to address and provide insights into the nature of causality, identity and nature. (kathleenrogers.co.uk)
  • In over 100 years of unrestricted investigation, human fetal tissue research has had ample time to prove useful, yet it has failed to do so. (californiafamily.org)
  • Therefore, in the last years characterization of macrophage phenotype in vivo during tissue repair has been a matter of active investigation. (hindawi.com)
  • For this investigation, a cluster-associated case was defined as isolation of L. monocytogenes serotype 1/2a from a normally sterile site (e.g., blood or cerebrospinal fluid) or from placental or fetal tissue (in the setting of miscarriage or stillbirth) since January 1, 2010, and PFGE pattern combination GX6A16.0001 and GX6A12.0001. (cdc.gov)
  • Recent on-going artworks are based on an EPRSC funded, Pathways to Impact (PiA) residency at the University of Southampton in the School of Medicine on Stem Cells and Regenerative Medicine exploring the use of stem cells in the area of Bone and Joint research. (kathleenrogers.co.uk)
  • Engendering public engagement with biotechnological, stem cell and regenerative medicine research, my work engages with the impact of these life sciences on human identity, culture and society. (kathleenrogers.co.uk)
  • I have harnessed elements regenerative medicine space to create a new body of research, developing this most recent artworks on an EPRSC funded, Pathways to Impact (PiA) residency in the School of Medicine on Stem Cells and Regenerative Medicine exploring the use of stem cells in the area of Bone and Joint research. (kathleenrogers.co.uk)
  • Exploring the different ways people might come to experience regenerative medicine, the work also reflects on how visual arts led research can improve public understanding of stem cell research. (kathleenrogers.co.uk)
  • Mesenchymal stem cells (MSCs) are the most commonly used cells in tissue engineering and regenerative medicine. (frontiersin.org)
  • Here, we identified the coding sequence of the EZH2 gene and characterized its expression pattern in fetal tissues of Duroc pigs at 65- and 90-day postcoitus (dpc). (hindawi.com)
  • Alternative splicing of gene can generate multiple transcripts and proteins to regulate tissue and organ development [ 17 ]. (hindawi.com)
  • Six patients had one or more underlying medical conditions (i.e., human immunodeficiency virus [HIV] infection, alcohol abuse, cancer, and diabetes mellitus). (cdc.gov)
  • On June 6, 1994, the U.S. Public Health Service convened a workshop in Bethesda, Maryland, to develop recommendations for the use of zidovudine to reduce the risk for perinatal transmission of human immunodeficiency virus (HIV). (cdc.gov)
  • These recommendations update the interim guidelines (1) developed by the U.S. Public Health Service for the use of zidovudine (ZDV) to reduce the risk for perinatal transmission of human immunodeficiency virus (HIV) infection. (cdc.gov)
  • Worldwide, perinatal (i.e., mother-to-infant) transmission accounts for most human immunodeficiency virus (HIV) infections among children. (cdc.gov)
  • 1990. A pilot study on the effects of Aroclor 1254 ingestion by rhesus and cynomolgus monkeys as a model for human ingestion of PCBs. (cdc.gov)
  • To do this, they had to produce an army of never-tiring taste testers - that is, flavor receptors engineered from human embryonic kidney cells (HEK-293, a fetal kidney cell line popular in pharmaceutical research). (hli.org)
  • EZH2, a methyltransferase catalyzing H3K27me3, has been abundantly studied in human and mouse embryonic development. (hindawi.com)
  • These results validated a different transcript in pigs and characterized its expression profile in fetal tissues of different gestation stages, which indicated that EZH2 played important roles during porcine embryonic development. (hindawi.com)
  • The investigators hope that this research will eventually lead to clinical trials of targeted treatments for LMS patients. (sarcomahelp.org)
  • Non-invasive prenatal genetic diagnosis is already in clinical use for fetal blood-type screening. (nature.com)
  • The Application Guidance Notes (AGNS) provide question by question guidance for filling out the UBC Clinical research ethics application. (ubc.ca)
  • The recent results of AIDS Clinical Trials Group Protocol 076, a controlled clinical trial sponsored by the National Institutes of Health in collaboration with the National Institute of Health and Medical Research and the National Agency of Research on AIDS in France, indicate that zidovudine administered to a selected group of HIV-infected women and their infants can reduce the risk for perinatal transmission of HIV by approximately two-thirds. (cdc.gov)
  • Biologists have known for decades that some fetal cells pass through the placenta and into the mother's blood stream. (nature.com)
  • The LeioMyoSarcoma Direct Research Foundation and the Liddy Shriver Sarcoma Initiative have come together to fund a $150,000 grant for promising leiomyosarcoma research at Stanford University. (sarcomahelp.org)
  • Two of the leading researchers in cell-free fetal DNA testing - Dennis Lo of the University of Hong Kong and Steve Quake of Stanford University in California - use different methods to analyse fetal cell-free DNA from maternal serum. (nature.com)
  • A common scenario is emerging, in which soon after injury infiltrating macrophages are mainly proinflammatory M1 macrophages, whereas M2 macrophages are the primary effectors of later stages of tissue repair or remodelling phases [ 10 - 12 ]. (hindawi.com)
  • The brave new world of widespread prenatal genetic diagnosis has been always 'arriving' since Nature published a paper by Danish researchers Fritz Fuchs and Povl Riis in 1956, reporting the first prenatal genetic testing in humans 4 . (nature.com)
  • Beyond their role in innate immunity, macrophages play increasingly defined roles in orchestrating the healing of various injured tissues. (hindawi.com)
  • A lot of evidence demonstrated that after acute injury M1 macrophages infiltrate early to promote the clearance of necrotic debris, whereas M2 macrophages appear later to sustain tissue healing. (hindawi.com)
  • In this paper, we discuss the current available information about the role that different phenotypes of macrophages plays after injury and during the remodelling phase in different tissue types, with particular attention to the skeletal muscle. (hindawi.com)
  • Macrophages are essential for the efficient healing of numerous tissues. (hindawi.com)
  • Macrophages participate in all the different phases of tissue repair: they can promote phagocytosis of cellular debris and apoptotic neutrophils and produce cytokines that may help orchestrate the healing response. (hindawi.com)
  • However, due to the release of proinflammatory cytokines and cytotoxic radical species, uncontrolled activity of macrophages may also be detrimental to tissue repair. (hindawi.com)
  • Indeed, several human diseases are characterized by attenuated repair responses and imbalances in the inflammatory response with increased number of infiltrating macrophages [ 3 - 5 ]. (hindawi.com)
  • Heterogeneity and plasticity of macrophages could explain these apparently contrasting roles in tissue healing. (hindawi.com)
  • Treatment of human alveolar macrophages (AMs) with the synthetic GC dexamethasone (Dex) did not alter the expression of TLRs −1, −4, and −6. (frontiersin.org)
  • Alveolar macrophages (AMs) are the tissue-resident macrophages in the lung alveolar space. (frontiersin.org)
  • The pig is an increasing important animal model for molecular study and pharmaceutical research. (hindawi.com)
  • The site-specific research was produced in association with Professor Richard OC Oreffo and the Bone and Joint Research Group at the Centre for Human Development, Stem Cells and Regeneration, Human Development and Health, Faculty of Medicine. (kathleenrogers.co.uk)
  • Use of trade names and commercial sources is for identification only and does not imply endorsement by the National Association of State Public Health Veterinarians, Council of State and Territorial Epidemiologists, Association of Avian Veterinarians, American Veterinary Medical Association, or the U.S. Department of Health and Human Services. (cdc.gov)
  • Aniline induces methemoglobinemia, which impairs the delivery of oxygen to tissues. (cdc.gov)
  • In vivo experiments confirmed mitochondrial abundance and mitochondrial oxygen consumption rates were elevated in host tissues following MSC treatment. (frontiersin.org)
  • The aim of this study was to identify any impact of CYP2A13 single-nucleotide polymorphisms (SNPs) on CYP2A13 expression in human lung. (aspetjournals.org)
  • CYP2A13 genetic polymorphisms may be associated with interindividual differences in susceptibility to tobacco-related tumorigenesis, because the resultant variations in CYP2A13 expression and metabolic activity can significantly alter the extent of NNK metabolic activation in human lung. (aspetjournals.org)
  • In the present study, we determined the potential impact of selected CYP2A13 SNPs on levels of CYP2A13 expression in human lung. (aspetjournals.org)
  • We first determined the level of total CYP2A13 mRNA in 18 normal lung biopsy tissues to assess the extent of interindividual variation. (aspetjournals.org)
  • Since identification of EZH2 in the research of protooncogene product Vav [ 3 ], studies have shown that EZH2 is highly expressed in tumorigenesis, which regulates the expression of tumor suppressor genes, such as in breast cancer, prostate cancer, and lung cancer [ 4 - 6 ]. (hindawi.com)
  • Retrospective testing of 3,232 serum samples from the general population and 518 serum samples from a high-risk group showed no evidence of human exposure to Neospora caninum in England. (cdc.gov)
  • This retrospective study sought immunologic evidence of human exposure to N. caninum in England. (cdc.gov)
  • Atlanta, GA: U.S. Department of Health and HUman Services, Office of External Affairs, Exposure and Disease Registry Branch, Agency for Toxic Substances and Disease Registry. (cdc.gov)
  • Fourth National Report on Human Exposure to Environmental Chemicals. (cdc.gov)
  • The MMWR series of publications is published by the Epidemiology Program Office, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services, Atlanta, GA 30333. (cdc.gov)
  • References to non-CDC sites on the Internet are provided as a service to MMWR readers and do not constitute or imply endorsement of these organizations or their programs by CDC or the U.S. Department of Health and Human Services. (cdc.gov)
  • In the absence of a human positive control, we used a primate serum sample as a further positive control. (cdc.gov)
  • Analysing the free-floating fragments of fetal DNA that exist in a pregnant woman's blood serum is proving more successful. (nature.com)
  • Humans could become exposed to N. caninum by accidental ingestion of oocysts shed in the feces of canid definitive hosts or following the consumption of raw or inadequately cooked meat that contains tissue cysts. (cdc.gov)
  • The main objection to the use of human cloning for reproductive purposes is that it would be contrary to human dignity as it would violate the uniqueness and indeterminateness of the human being. (who.int)
  • Leaving newborns to die is horrible, but letting scientists pick through their bodies for parts is an even larger affront to human dignity. (californiafamily.org)
  • Jaime Herrera Beutler (R-Wash) said last year , "Treating these tiny humans like a junkyard, where groups like Planned Parenthood can scavenge for parts, is hardly the retail business anyone should want to hang a shingle over. (californiafamily.org)
  • Regenerative phenomena associated with stem cells touch on the deepest aspects of human identity. (kathleenrogers.co.uk)
  • Stem cell transfer treatments replace non-functioning and dead cells at tissue sites within the body with healthy donor cells. (kathleenrogers.co.uk)
  • Unfortunately in most cases these compounds also damage normal human cells, and that damage limits the amount of drug that can be tolerated by patients. (sarcomahelp.org)
  • Targeted' therapy starts with the discovery of a protein that is expressed on the surface of tumor cells but not (or in a limited way) in normal human tissues. (sarcomahelp.org)
  • Which Cosmetics Use Fetal Cells? (hli.org)
  • Your children might enjoy using coffee creamers and eat soup with artificial flavor enhancers (Senomyx and Firmenich) tested on artificial taste buds engineered from aborted fetal cells. (hli.org)
  • In a 2012 letter to Children of God for Life, PepsiCo stated that "Senomyx does not use HEK cells or any other tissues or cell lines derived from human embryos or babies for research performed on behalf of PepsiCo. (hli.org)
  • The merge does not seem to have stopped the use of aborted fetal cells in development. (hli.org)
  • Each year, less than 2% of pregnant women in the United States undergo amniocentesis (in which a small amount of amniotic fluid containing fetal cells is taken for analysis) or chorionic villus sampling (CVS - in which fetal tissue is extracted from the placenta). (nature.com)
  • Technical problems have hampered attempts to isolate individual fetal cells and, even when such cells could be found, there was no guarantee that they were from the present pregnancy. (nature.com)
  • Skulls Unlimited International, Inc. is committed to providing legally and ethically obtained natural bone osteological specimens as well as the finest replica specimens to the educational, medical and research communities. (skullsunlimited.com)
  • These preparatory interregional and interdisciplinary meetings focused on the following areas: cloning and human reproductive health, biologicals, organ transplantation, research, and medical genetics. (who.int)
  • They emphasize the need to promote the teaching of ethics in medical education and to establish effective measures to protect developing countries from the risk of unregulated expatriate research involving human subjects. (who.int)
  • Gosden and his colleagues explored this idea by freezing strips of ovarian tissue donated by women undergoing medical treatments. (discovermagazine.com)
  • In order to achieve this important goal, we need to make sure that scientists and medical professionals have access to the research and resources necessary to protect the population and safeguard the most vulnerable among us, including pregnant women and children. (californiafamily.org)
  • Fetal tissue HAS NOT produced a single medical treatment. (californiafamily.org)
  • The Vaccine Chart of the Sound Choice Pharmaceutical Institute (SCPI) lists dozens of vaccines and medical products that contain aborted fetal cell lines. (hli.org)
  • A small sample - often antiques that simply do not qualify for medical/research grade usage - are made available to osteology enthusiasts worldwide so that they may continue to educate and inform. (skullsunlimited.com)
  • Before the announcement in February 1997 of the cloning of a sheep by somatic cell nuclear transfer, existing legislation in a number of countries already precluded human cloning for reproductive purposes, sometimes implicitly. (who.int)
  • My research engages with contemporary debates in biotechnology and stem cell research and I have developed numerous works through art and science collaboration that contribute to public critical understanding and discussion of these domains. (kathleenrogers.co.uk)
  • The research residency enabled close observation and artistic reflection on the science of osteo-specific differentiation, function and signaling pathways in stem cell populations. (kathleenrogers.co.uk)
  • The mature egg cell, observes Roger Gosden, a reproductive biologist at the University of Leeds in England, is the rarest cell in the human body. (discovermagazine.com)
  • The fetal skin cell line that PSPs are based on was taken from an electively aborted baby whose body was donated to the University. (hli.org)
  • Employing in vitro cell culture of inherited mitochondrial disease and an in vivo animal experimental model of low-grade inflammation (high fat feeding), we show human-derived MSCs to alter mitochondrial function. (frontiersin.org)
  • To date, a lot of EZH2 variants have been found in various cell and tissue types [ 18 - 20 ]. (hindawi.com)
  • The Initiative has funded five LMS research grants and one study open to several types of sarcoma patients, including those with LMS. (sarcomahelp.org)
  • It reports on implementation of resolution WHA50.37 concerning ethical, scientific and social implications of cloning in human health. (who.int)
  • Resolution WHA50.37 requested the Director-General to clarify the potential applications of cloning procedures in human health and their ethical, scientific and social implications. (who.int)
  • In terms of existing ethical guidelines for biomedical research involving human subjects, human cloning for reproductive purposes raises concerns about risk in relation to benefit, informed consent, and accountability. (who.int)
  • Regulators, doctors and patients need to prepare for the ethical, legal and practical effects of sequencing fetal genomes from mothers' blood, says Henry T. Greely. (nature.com)
  • Food and beverages do not contain any aborted fetal material but may be tastier because of the nature of the research done in their development. (hli.org)
  • In the present study, we examine the specific impacts of MSCs on mitochondrial morphology and function in host tissues. (frontiersin.org)
  • Considering the varieties of EZH2 splicing variant, identifying its transcript in porcine fetal tissues is the foundation to study its function. (hindawi.com)
  • In this study, we identified a transcript variant of EZH2 in porcine fetal tissues by cloning and sequencing. (hindawi.com)
  • Please make sure you have added yourself as either the Principal Investigator, primary contact, co-investigator, or a study team member with online access in order to continue with the application. (ubc.ca)
  • Cosmopolitical Futures, The Anthropocenic Human series reflects my long time interest and research in foundational studies in theories of quantum physics and the nature of nature and the properties of living matter. (kathleenrogers.co.uk)
  • That was an excellent suggestion, as at that time I was orienting myself on which sarcoma I wanted to go into in more detail, and I felt that leiomyosarcomas were relatively understudied within the group of soft tissue tumors, while they constituted a considerable percentage of these tumors. (sarcomahelp.org)
  • Wasting no time in response, California Attorney General Xavier Becerra, along with 15 other Attorneys General, sent a letter on Thursday to President Trump and the Department of Health and Human Services, urging the administration to end the ban on federal funds for research using fetal tissue from abortions. (californiafamily.org)
  • They contribute to homeostatic tissue remodelling during foetal life [ 1 , 2 ] and in several tissues in the adult. (hindawi.com)
  • As a decisive step towards the artificial production of human beings, it would increase the risk of reducing people to objects. (who.int)
  • Products related to fetal material can be broken down into three categories: artificial flavors, cosmetics, and medicines/vaccines. (hli.org)
  • The healing process consists of overlapping phases of inflammation, tissue formation, and remodelling with reorganization of vasculature and extracellular matrix. (hindawi.com)
  • They participate in polarized Th2 reactions, parasite clearance, damping of inflammation, and promotion of angiogenesis and tissue remodelling [ 7 , 8 ]. (hindawi.com)
  • 1998. Profiles of Great Lakes critical pollutants: a sentinel analysis of human blood and urine. (cdc.gov)
  • The move by the Department of Health and Human Services is a step in the right direction - what Becerra is arguing in favor of - is not. (californiafamily.org)
  • US Department of Health and Human Services, Public Health Service Atalanta, GA. (cdc.gov)
  • He understood the intentional state of mind as arising from complex networks of human and non-human agents and ecologies of material conditions that exceed an individual and he saw how the paradoxical challenge for humankind was to make meaning and intelligibility in the light of unintelligibility and in doing so he endorsed, trans disciplinary creative processes and practices of poetry and the visual arts. (kathleenrogers.co.uk)
  • Because of the complexities of Food and Drug Administration (FDA) labeling, you would probably not know that these products use aborted fetal parts unless someone informed you. (hli.org)
  • If a primary contact is not selected, the PI will be the only person to receive all correspondence from the Research Ethics Board Administration (REBA). (ubc.ca)
  • 1977. The health effects of PCBS with particular emphasis on human high risk groups. (cdc.gov)
  • So far, the expression pattern and the function of EZH2 have been broadly studied in humans [ 11 ] and mice [ 12 , 13 ]. (hindawi.com)
  • We believe education is the greatest gift osteology can share and that every human specimen can contribute to the advancement of science. (skullsunlimited.com)
  • It is necessary in small amounts for human health, growth, and sense of taste. (medlineplus.gov)
  • The Initiative's Research Grants Program encourages collaboration to fight a disease that knows no borders. (sarcomahelp.org)
  • No one knew whether human ovarian tissue could survive the process--after all, that kind of deep freeze normally kills mature eggs. (discovermagazine.com)
  • One version of the approach he envisions involves giving a woman back some of her ovarian tissue if she has been somehow sterilized. (discovermagazine.com)
  • Roger Gosden is the most outspoken champion of transplanting ovarian tissue and has provided much of the experimental support for it. (discovermagazine.com)
  • But co-founder Josh Morrison hopes to show that there is broad support for human-challenge trials, which have the potential to deliver an effective coronavirus vaccine more quickly than standard trials. (nature.com)