• In addition, formalin fixed paraffin embedded tissue was obtained from eight patients with an earlier diagnosis of sarcoidosis who were still being followed up. (bmj.com)
  • To study the effect of tap water `softening' (i.e. calcium extraction) on H&E stains, 5 sets of slides from 30 different paraffin-embedded human pathologic tissue blocks were prepared in the same way except for washing with 5 different types of water. (who.int)
  • Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC-exosomes) attenuate AD-like symptoms by reducing multiple inflammatory cytokine levels. (mdpi.com)
  • 18 F -fluorodeoxyglucose positron emission tomography combined with computed tomography (FDG-PET/CT) is widely used as a standard method for evaluating human brown adipose tissue (BAT), a recognized therapeutic target of obesity. (spiedigitallibrary.org)
  • Brown adipose tissue (BAT) is known to play a critical role in cold-induced nonshivering thermogenesis (CIT) to maintain body temperature. (spiedigitallibrary.org)
  • That adipose tissue will be burned off as a result. (fosep.org)
  • From the Uppsala EXODIAB biobank, we can also receive other tissues such as muscle, liver and adipose tissue which are targets for insulin action, blood vessels which are involved in development of complications, lymph nodes and spleen which are important tissues for assessing type 1 diabetes, and intestine which secretes hormones important for insulin secretion. (lu.se)
  • METHODS Fresh tissue samples (node or lung biopsy) taken from 23 patients with newly diagnosed sarcoidosis, 10 with other respiratory disease, and four patients with culture positive tuberculosis were analysed using PCR to amplify a 123 bp fragment of IS6110, the insertion element present in MTb, and nested PCR to further amplify an 85 bp sequence within the 123 bp product. (bmj.com)
  • We first determined the level of total CYP2A13 mRNA in 18 normal lung biopsy tissues to assess the extent of interindividual variation. (aspetjournals.org)
  • In the present study, we aimed to investigate the effects of continuous intake of aqueous extract from I. obliquus on tumor suppression. (researchgate.net)
  • Main methods: Anticancer activity of the I. obliquus extract was examined in mouse models of Lewis lung carcinoma growth and spontaneous metastasis after 3 weeks of continuous extract intake at the dose of 6 mg/kg/day, which corresponded to that ingested daily with Chaga infusion in Japan. (researchgate.net)
  • miR-127 is originally found to be highly expressed in human and murine embryos and has a critical role in lung development and placental formation [ 34 , 35 ]. (hindawi.com)
  • In this study, we sought to determine the expressions of miR-127 in the lung tissues of sodium taurocholate-induced AP models in rats and that in plasma of AP patients and to preliminarily explore the association of miR-217 levels and LI. (hindawi.com)
  • The aim of this study was to identify any impact of CYP2A13 single-nucleotide polymorphisms (SNPs) on CYP2A13 expression in human lung. (aspetjournals.org)
  • CYP2A13 genetic polymorphisms may be associated with interindividual differences in susceptibility to tobacco-related tumorigenesis, because the resultant variations in CYP2A13 expression and metabolic activity can significantly alter the extent of NNK metabolic activation in human lung. (aspetjournals.org)
  • In the present study, we determined the potential impact of selected CYP2A13 SNPs on levels of CYP2A13 expression in human lung. (aspetjournals.org)
  • Click on any transcript to open the specific mRNA page, to see the exact cDNA clone support and eventual SNPs and to get details on tissues, sequences, mRNA and protein annotations. (nih.gov)
  • 1% sodium bicarbonate (NaHCO ) dis- ions in tissues such as collagen or muscle. (who.int)
  • Collagen is the most plentiful protein found in humans and animals. (healthline.com)
  • Luckily, collagen can be extracted from these parts by boiling them in water. (healthline.com)
  • In addition, DNA and proteins can be recovered, which makes AGPC an attractive source for integrative analysis on tissues of which little material is available, such as clinical specimens. (nih.gov)
  • A total of 30 different human pathology tis- available as powders or ready-to-use solu- sue specimens embedded in paraffin tions. (who.int)
  • The tissue specimens included lon campechianum [ 1 ]. (who.int)
  • Employing human proteome arrays, we profiled the antibodies extracted from explanted SAH, alcoholic cirrhosis (AC), nonalcoholic steatohepatitis (NASH), primary biliary cholangitis (PBC), autoimmune hepatitis (AIH), hepatitis B virus (HBV), hepatitis C virus (HCV) and HD livers and found that antibodies of IgG and IgA isotypes were highly accumulated in SAH and recognized a unique set of human proteins as autoantigens. (elifesciences.org)
  • Employing in vitro cell culture of inherited mitochondrial disease and an in vivo animal experimental model of low-grade inflammation (high fat feeding), we show human-derived MSCs to alter mitochondrial function. (frontiersin.org)
  • AceView: gene:dpy-21, a comprehensive annotation of human, mouse and worm genes with mRNAs or ESTsAceView. (nih.gov)
  • Conserved transcription factor-binding sites within promoter regions of human RON genes were then searched. (spandidos-publications.com)
  • The cornea is one of the most transparent and non-vascularized tissues in the human body, and several active genes [ 1 , 2 ] are thought to be involved in maintaining the homeostasis of the cornea. (molvis.org)
  • Chronic infections around the tooth root can destroy bone, ligaments, and other supporting tissues. (cdhp.org)
  • The methylation status and protein expression levels of RUNX3 were measured by methylation-specific PCR and Western blot in 136 and 72 different malignancy grade glioma tissues, respectively. (hindawi.com)
  • We analyse two comprehensive transcriptome datasets from human tissues and human-derived cell lines in terms of the expression profiles of the SLC and ABC families of membrane transporters. (biorxiv.org)
  • The Gini index (coefficient) characterises inequalities of distributions, and is used in a novel way to describe the distribution of the expression of each transporter among the different tissues and cell lines. (biorxiv.org)
  • Similar trends hold true for the expression profiles of transporters in different cell lines, suggesting that cell lines exhibit largely similar transport behaviour to that of tissues. (biorxiv.org)
  • A comprehensive understanding of gene expression in human RB is essential for the development of safe and effective new therapies. (molvis.org)
  • We reviewed published microarray and RNA sequencing studies in which gene expression profiles were compared between human RB and normal retina tissues. (molvis.org)
  • Expression of DCT was absent or barely detected in retina tissues, various human ocular cells, and major organs. (molvis.org)
  • To this end RNA-sequencing will be performed to study differences in allele specific expression and splice isoform pattern between different human tissues. (lu.se)
  • Despite this potential, AGPC has only scarcely been used for proteomic analysis, mainly due to difficulties in extracting proteins. (nih.gov)
  • We have used a quantitative mass spectrometry method to show that proteins can readily be recovered from AGPC extracted tissues with high recovery and repeatability, which allows this method to be used for global proteomic profiling. (nih.gov)
  • We sought to determine if there was antibody deposition in SAH livers and whether antibodies extracted from SAH livers were cross-reactive against both bacterial antigens and human proteins. (elifesciences.org)
  • The aim of this study was to collect prospectively tissue from patients with sarcoidosis in whom tuberculosis had been excluded, and to use polymerase chain reaction (PCR) to search for DNA sequences specific for MTb. (bmj.com)
  • The aim of this study was to collect prospectively tissue from a carefully characterised cohort of patients with newly diagnosed sarcoidosis in whom tuberculous infection or prior disease had been excluded and to use PCR to search for DNA sequences specific for MTb. (bmj.com)
  • La teneur faible en ions calcium et magnésium et élevée en ions sodium de l'eau douce affecte négativement les résultats de la coloration de routine à l'hématoxyline-éosine. (who.int)
  • We analyzed immunoglobulins (Ig) in explanted livers from SAH patients (n=45) undergoing liver transplantation and tissue from corresponding healthy donors (HD, n=10) and found massive deposition of IgG and IgA isotype antibodies associated with complement fragment C3d and C4d staining in ballooned hepatocytes in SAH livers. (elifesciences.org)
  • The study would benefit from a broader analysis of gut microbiota proteome and further characterization of B cells infiltrating the liver tissue including their numbers/field and their origin (infiltrating versus resident cells). (elifesciences.org)
  • Thus, BAT is expected to be a therapeutic target for obesity and related metabolic disorders in humans. (spiedigitallibrary.org)
  • CYP2A13 is a human cytochrome P450 monooxygenase that is efficient in the metabolic activation of tobacco-specific nitrosamines. (aspetjournals.org)
  • The levels of miR-127 in the tissues and plasma were detected using quantitative reverse transcription-polymerase chain reaction (qRT-PCR). (hindawi.com)
  • Thus, NIR TRS can be applied for quantitative assessment of BAT in longitudinal intervention studies in humans. (spiedigitallibrary.org)
  • Such extracts aid in accelerating the absorption of nutrients. (fosep.org)
  • Acid guanidinium thiocyanate, phenol, and chloroform extraction (AGPC) is a commonly used procedure to extract RNA from fresh frozen tissues and cell lines. (nih.gov)
  • Tissue quantification of neutral and acid mucins in the mucosa of the colon with and without fecal stream in rats. (scielo.br)
  • The exact amino acid composition varies depending on the type of animal tissue used and the method of preparation. (healthline.com)
  • To verify if the application of enemas containing oily extracts of curcumin preserves the tissue content of mucins in the glands of the colonic mucosa without fecal stream. (scielo.br)
  • On the other hand, we have what are called protomorphogens, or extracts of tissues from glands such as adrenal, pancreas, pituitary, thyroid, and ovary, which can be taken orally to help support those particular tissues in humans. (healthy.net)
  • On the positive side, it is likely that the basic components of those gland tissues may offer the precursor substances that our own bodies and glands can use to enhance their functions. (healthy.net)
  • Some evidence from radioisotope studies suggests that glands, when eaten, do in fact get to the human glands and influence them. (healthy.net)
  • Technology and medical endocrinology evolved this therapy by isolating specific hormones at the source of the glands' activities (just as we extracted the active pharmaceutical drugs from whole plants). (healthy.net)
  • Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)
  • Herbs and herbal tinctures address the specific, rare nutritional imbalances that cause connective tissue inflammation. (life-enthusiast.com)
  • The human tissue laboratory (HTL) is collaboration between EXODIAB and the Nordic Network for Clinical Islet Transplantation. (lu.se)
  • Sociodemographic data on vaccination and clinical characteristics of Covid-19 cases were extracted from the national COVID-19databases of the Public Health Emergency Center and the Expanded Program on Immunization. (bvsalud.org)
  • In vivo experiments confirmed mitochondrial abundance and mitochondrial oxygen consumption rates were elevated in host tissues following MSC treatment. (frontiersin.org)
  • T he use of animal tissues in treatment of disease and support of health is a controversial one in medicine, with opinions ranging from useless to miraculous. (healthy.net)
  • Extracting protruding, misaligned or blocked-out canines can help create space for movement and alignment of other teeth as part of an orthodontic treatment plan. (cdhp.org)
  • Mean ± SD scores for lameness (A), joint flexion (B), and joint effusion (C) in horses that had undergone experimental induction of osteoarthritis in 1 middle carpal joint and a sham operation in the other middle carpal joint, followed by oral treatment with ASU extracts (1:2 [avocado-to-soybean] ratio mixed in 6 mL of molasses) or molasses (6 mL) alone (placebo treatment) once daily from days 0 to 70. (avma.org)
  • Near-infrared time-resolved spectroscopy ( NIR TRS ) is a technique for evaluating human BAT density noninvasively. (spiedigitallibrary.org)
  • process, tissue fixation methods, pH and 1. (who.int)
  • Mesenchymal stem cells (MSCs) are the most commonly used cells in tissue engineering and regenerative medicine. (frontiersin.org)
  • The nuclei of cells samples from the endometrium, appendix, are stained by its active product, haematin, gall bladder, spleen and other gastric and which is produced when an oxidizing agent pleural tissues obtained by surgery, curet- is added. (who.int)
  • A growing number of publications are based on results from the Human Tissue Laboratory. (lu.se)
  • BACKGROUND Although some studies have reported the presence of Mycobacterium tuberculosis (MTb) DNA in tissues affected by sarcoidosis, the data are conflicting. (bmj.com)
  • MSCs can promote host tissue repair through several different mechanisms including donor cell engraftment, release of cell signaling factors, and the transfer of healthy organelles to the host. (frontiersin.org)
  • Finally, receiving human donor material is a great opportunity coupled to great responsibilities. (lu.se)
  • This article will take an in-depth look at the key considerations around canine tooth extraction in humans. (cdhp.org)
  • Abnormal fluid-filled sacs or benign/malignant tissue growths on canines may necessitate extraction. (cdhp.org)
  • Afin d'étudier l'effet de l'adoucissement de l'eau du robinet (extraction du calcium) sur les colorations à l'hématoxyline et à l'éosine, cinq (5) séries de lames issues de 30 blocs de tissus pathologiques humains différents inclus en paraffine ont été préparées de la même manière, sauf pour le lavage qui a été effectué avec cinq types d'eau différents. (who.int)
  • Today, both individual synthetic hormones and measured active thyroid tissue are used to support or replace thyroid activity. (healthy.net)
  • Synthetic peptide corresponding to Human VEGF Receptor 2 (phospho Y951). (abcam.com)
  • By contrast, the Gini coefficients for ABC transporters tend to be larger in cell lines than in tissues, implying that some kind of a selection process has taken place. (biorxiv.org)
  • The lowest four in tissues are FAM32A, ABCB7, MRPL21 and PCBP1, while the lowest three in cell lines are SF3B2, NXF1 and RBM45. (biorxiv.org)
  • PCBP1 is both reasonably highly expressed and has a low Gini coefficient in both tissues and cell lines, and is an excellent novel housekeeping gene. (biorxiv.org)
  • Altogether there are four main datasets, namely 409 "SLCs" in 59 tissue types and 56 cell lines, and 48 ABCs in the same tissue types and cell lines. (biorxiv.org)
  • Little information was found on the direct detection of sulfur mustard in biological tissues or fluids. (cdc.gov)
  • RESULTS MTb DNA was not detected in any of the tissue samples from patients with sarcoidosis or other respiratory disease but was found in all four patients with tuberculosis. (bmj.com)
  • Some investigators have found evidence of MTb in tissues using the polymerase chain reaction (PCR) to amplify mycobacterial DNA or rRNA 6-8 but more recent studies have failed to identify such organisms in the majority of tissue samples from patients with sarcoidosis. (bmj.com)
  • We found that DCT was highly expressed in six of 13 samples microdissected from Thai RB tissues. (molvis.org)
  • 5 , 6 Moreover, BAT is also suggested to participate in glucose homeostasis 7 - 10 and to improve blood lipid profiles 11 in humans. (spiedigitallibrary.org)
  • DNA was extracted from the blood and subjected to mutation analysis by sequencing of the PIKFYVE gene. (molvis.org)
  • BAT activity and/or mass can be quantified by FDG-PET/CT after acute cold exposure, which is widely used as a standard method in humans. (spiedigitallibrary.org)
  • Fresh tissue samples were prospectively collected from a cohort of 23 patients with newly diagnosed sarcoidosis all seen at one outpatient clinic at one hospital. (bmj.com)
  • Topical antibacterial and antifungal properties support healthy tissue regeneration to help repair skin sores and wounds Supports your natural internal cleansing response Helps cleanse urinary and digestive systems May increase strength needed for daily work Supports healthy sleep (rise earlier with more energy and strength). (life-enthusiast.com)
  • In many cases, transporters exhibit extremely high Gini coefficients, even when their supposed substrates might be expected to be available to all tissues, indicating a much higher degree of specialisation than is usually assumed. (biorxiv.org)
  • Influence of the application of enemas with oily extract of curcumin ( Curcuma longa ) on the tissue content of neutral and acidic mucins in the colonic mucosa without fecal stream ☆ ☆ Study conducted at Universidade São Francisco (USF), Programa de Pós-Graduação em Ciências da Saúde, Laboratório de Investigação Médica (LIM), Bragança Paulista, SP, Brazil. (scielo.br)
  • There was an increase in the tissue content of neutral mucins in animals treated with curcumin at a concentration of 50 mg/kg/day for four weeks, whereas in the group treated with 200 mg/kg/day there was an increase independent of the time of intervention. (scielo.br)
  • Significance: Our findings suggest that the I. obliquus extract could be used as a natural remedy for cancer suppression by promoting energy metabolism. (researchgate.net)
  • sulfate, were present in the same total amount and proportions in both tissues. (eurekamag.com)
  • A total of 236 acupuncture prescriptions were extracted, involving 61 acupoints, with a total frequency of occurrence being 846. (bvsalud.org)
  • Its di-electric properties are extracted by model calculations and compared to the properties of some selected human tissues. (jpier.org)
  • Mouse over the ending of each transcript gives tissues from which the supporting cDNAs were extracted. (nih.gov)
  • Moreover, I. obliquus extract-treated mice demonstrated the increase in tumor agglomeration and inhibition of vascularization. (researchgate.net)
  • The gelatin extracted during this process is flavorless and colorless. (healthline.com)
  • Even better, it has plenty of phytonutrients that should maintain the body's tissues young and vibrant. (fosep.org)
  • The 2 types of candidiasis that cause white oral tissue include pseudomembranous candidiasis and chronic/hyperplastic candidiasis. (medscape.com)