• From the ethical point of view, so-called therapeutic cloning is even more serious. (archdiocese-no.org)
  • It is gravely immoral to sacrifice a human life for therapeutic ends. (archdiocese-no.org)
  • Therapeutic cloning, which creates embryonic stem cells . (medlineplus.gov)
  • The heated debate in our society over reproductive cloning, as well as therapeutic cloning to obtain embryonic stem cells, has been fueled by misconceptions and hyperbole on both sides. (flfamily.org)
  • In therapeutic cloning, the blastocyst is not transferred to a womb. (eurostemcell.org)
  • Another long-term hope for therapeutic cloning is that it could be used to generate cells that are genetically identical to a patient. (eurostemcell.org)
  • To date, no human embryonic stem cell lines have been derived using therapeutic cloning, so both these possibilities remain very much in the future. (eurostemcell.org)
  • 5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
  • With Hwang discredited, both the field of therapeutic cloning and the public's trust in science have suffered a serious setback. (nature.com)
  • A well-respected medical ethicist from one of Canada's leading universities says Canada must not legalize embryonic cloning for any purpose, including therapeutic purposes. (catholicnewsagency.com)
  • The reader benefits from the scholar's clear explanation about embryonic stem-cell research and therapeutic cloning. (catholicnewsagency.com)
  • Human cloning ought to be banned, both reproductive cloning and so-called therapeutic cloning-or as Stanford University recently referred to it, "human nuclear transplantation. (probe.org)
  • The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)
  • Although attempts have not yet been made to create a therapeutic transplant from embryonic stem cells, the methods have been developed to allow the creation of functional, mature cells using human cell cloning technology. (news-medical.net)
  • An Australian ban on therapeutic cloning was lifted in December 2006 after a long debate in Federal parliament. (bioedge.org)
  • With this background information as a foundation, we then discuss each of the key questions in relation to the upcoming therapeutic trial and critically assess if the time is ripe for clinical translation of parthenogenetic stem cell technology in Parkinson's disease. (lu.se)
  • Opponents argue that any embryo has the potential to develop into a mature human. (cbc.ca)
  • After many divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original donor who provided the adult cell - a genetic clone. (eurostemcell.org)
  • Bush promised in January to review a Clinton administration rule that allowed federal funding for researchers experimenting on embryo cells from fertility clinics. (christianitytoday.com)
  • Under the rule, a third party could destroy the embryo by taking it apart and preserving the remaining living stem cells for research. (christianitytoday.com)
  • But many believe the destruction of a human embryo is the destruction of human life and should not be allowed for any reason. (christianitytoday.com)
  • 2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
  • Ellington, who refused to compromise even at the urging of Gov. Blanco, said his support stems from his views that the embryo is not a human life. (lifenews.com)
  • We want real cures now available from ethical adult stem cell research, not illusory promises from unproductive embryo research,' the Louisiana Coalition for Ethical Stem Cell Research said in a statement. (lifenews.com)
  • For instance, he wonders-just an intellectual puzzle, he assures me, that he would never want to do-What would happen if scientists injected human stem cells into a monkey embryo? (discovermagazine.com)
  • Nearly all the cells in the stalled embryo had turned into brain cells, simply because a single protein had been stopped. (discovermagazine.com)
  • They instead refer to the embryo as a "clump of cells" or as "potential human life," Somerville says, "despite the fact that they are, given the right conditions, human life with the potential to go on living for years and years, just like all of us. (catholicnewsagency.com)
  • This means that anything that happens to the embryo from that point onward is the harming of a human being. (ipl.org)
  • In fact to get a embryonic stem cell a human embryo has to be disassembled. (ipl.org)
  • The destruction and use of a human embryo should not be allow to happen. (ipl.org)
  • People who believe that an embryo should not be destroyed tend to say that embryonic stem cell research should not be conducted. (ipl.org)
  • But Democratic Party Senator Mary Landrieu opposes the embryo cloning and stem cell work being done in South Korea. (voanews.com)
  • Cloning, or somatic cell nuclear transfer (SCNT), is the technique used to produce Dolly the sheep, the first animal to be produced as a genetic copy of another adult. (eurostemcell.org)
  • Somatic cell nuclear transfer (SCNT) is a type of cloning that has to be done in a lab. (bartleby.com)
  • One cloning technology that has been developed for mammalian and human cells is somatic cell nuclear transfer (SCNT). (news-medical.net)
  • The most famous clone was a Scottish sheep named Dolly. (medlineplus.gov)
  • To produce Dolly, the cloned blastocyst was transferred into the womb of a recipient ewe, where it developed and when born quickly became the world's most famous lamb. (eurostemcell.org)
  • He stayed on to earn his Ph.D. in molecular biology at Cambridge, training under the legendary geneticist John Gurdon, whose breakthroughs in the 1950s and 1960s were key to the experiments performed by Ian Wilmut, a Gurdon student who cloned Dolly the sheep in 1997. (discovermagazine.com)
  • This has led to a lot of interest in SCNT, which is best known as the method used to pioneer whole animal cloning technology, such as Dolly the sheep. (news-medical.net)
  • He was in high school when he heard about Dolly, one of the world's most extreme examples of cell reprogramming. (lu.se)
  • Through the cloning of Dolly, we learned that the cell nucleus contains all the genetic information needed for the cell to develop into any type of cell. (lu.se)
  • Instead, embryonic stem cells are isolated from the cloned blastocyst. (eurostemcell.org)
  • In SCNT they take the nucleolus out of an egg cell, replace it with the nucleolus of a somatic cell (body cell with two complete sets of chromosomes), and make the egg cell divide into a blastocyst ("What Is Cloning? (bartleby.com)
  • Embryonic stem cells are pluripotent - they have the ability to become virtually any type of cell within the body. (cbc.ca)
  • The resulting cells were pluripotent and could be differentiated into insulin-producing beta cells to restore the function of the pancreas in the donor. (news-medical.net)
  • Using our recently established haploid human pluripotent stem cells (hPSCs), we generated a genome-wide loss-of-function library targeting 18,166 protein-coding genes to define the essential genes in hPSCs. (nature.com)
  • The proliferation and differentiation of pluripotent stem cells give rise to progeny that can populate the entire immunologic and hematopoietic systems through committed progenitors of both the lymphoid and myeloid lineages. (medscape.com)
  • Dr Hwang, 52, gained worldwide fame after producing the world's first cloned human embryos and stem cells tailored to be used on individuals. (bbc.co.uk)
  • Often aborted babies are harvested for Stem Cell Research. (archdiocese-no.org)
  • Catholic teaching on difficult issues, like stem cell research and cloning, must be understood in order to recognize and respect all human life. (catholicscomehome.org)
  • The professor said he was resigning from all public posts, including his chairmanship of the World Stem Cell Hub, which is designed to produce stem cell lines for disease research worldwide. (bbc.co.uk)
  • The research conducted by his team requires large numbers of human eggs, which are difficult to obtain. (bbc.co.uk)
  • In December 1999, the editors of Science, the journal devoted to scientific and medical matters, called stem cell research the 'Breakthrough of the Year. (cbc.ca)
  • Since then, there has been a flurry of announcements about developments in stem cell research and hints of promising treatments for diseases such as Alzheimer's, Parkinson's and cancer. (cbc.ca)
  • In May 2007, Ontario and California announced a $30-million stem cell research deal aimed at finding new therapies for those diseases. (cbc.ca)
  • Ontario and California together account for about 70 per cent of the stem cell research currently conducted in North America. (cbc.ca)
  • Some of that money would be aimed at turning the state into the second-largest stem cell research region in the United States. (cbc.ca)
  • This new method of generating stem cells does not require embryos as starting points and could be used to generate cells from many adult tissues, such as a patient's own skin cells,' said principal author Andras Nagy, senior investigator at Mount Sinai's Samuel Lunenfeld Research Institute. (cbc.ca)
  • Paul Wagle, M.A., discusses his experience with a life-saving adult stem cell treatment, and the importance of promoting ethical approaches to medical research. (flfamily.org)
  • CLI's Vice President and Research Director, Dr. David Prentice, recently joined Molly Smith, host of From the Median, to explain the science, history, and politics of stem cells. (flfamily.org)
  • Pro-cloning forces have been working hard to convince state governments to pass constitutional amendments enshrining a "right" to clone and to destroy embryos for research. (flfamily.org)
  • Lee Byeong-chun and Kang Seung-keun have been charged with faking, together with Wang Woo-suk, the results of embryonic stem cell research and of embezzling public funds for the studies. (asianews.it)
  • Seoul (AsiaNews) Seoul National University (SNU) yesterday suspended two colleagues of Hwang Woo-suk, a vet and university professor charged with faking his research results on human cloning. (asianews.it)
  • What is cloning, and what does it have to do with stem cell research? (eurostemcell.org)
  • This form of cloning is unrelated to stem cell research. (eurostemcell.org)
  • The rule circumvented a 1995 congressional ban on using federal money for biomedical research on embryos outside the womb by allowing researchers to use stem cells extracted by a third party. (christianitytoday.com)
  • The Family Research Council, Focus on the Family, Concerned Women for America, the National Right to Life Committee and the Catholic Alliance had all stepped up pressure on Bush, arguing that federal funding would condone the destruction of human lives in the name of medical research. (christianitytoday.com)
  • The prolife lobby also received help from Do No Harm, a coalition of researchers, bioethicists, and doctors who spearheaded a nationwide petition urging Bush to oppose destructive human embryonic stem-cell research. (christianitytoday.com)
  • Bush's announcement grieved patients' groups and many in the scientific and medical communities who believe embryonic stem-cell research could provide a cure for millions. (christianitytoday.com)
  • A report published by the nonpartisan Center for Public Integrity (CPI) quoted a National Institutes of Health official who said that "the fledgling stem-cell industry would profit tremendously from federal funding that would cover embryonic stem-cell research. (christianitytoday.com)
  • Biotechnology companies specializing in stem-cell research stand to reap huge financial windfalls from successful therapies developed via this science," said the CPI report. (christianitytoday.com)
  • Funding for stem cell research in two of the most liberal states in the nation - California and Maryland - appears to be shifting away from embryonic to adult stem cells. (womenofgrace.com)
  • However, there is hope for the future as Governor Kathleen Blanco told pro-life advocates that she does not support embryonic stem cell research, and favors the wholesale cloning bans that pro-life organizations had backed. (lifenews.com)
  • Governor Blanco discussed the bills with the Louisiana Coalition for Ethical Stem Cell Research on the final day of the session, and said that bills banning reproductive cloning but allowing for destructive embryonic research, such as the one sponsored by Senate President Don Hines (D-Bunkie), would not receive her support. (lifenews.com)
  • The two other cloning bans, both wholesale bans that would have prohibited the destructive research, overcame many obstacles to come close to passage, and eventually garnered the support of a majority of the legislature. (lifenews.com)
  • The legislation, which bans reproductive cloning as well as embryonic stem cell research in which human life is destroyed, was amended in the House last week to outlaw the cloning process to create human embryos for research, but would allow importation of embryonic stem cell lines created outside the state for research. (lifenews.com)
  • Finally, the cloners see that there is no political stability for their clone and kill labs in Louisiana, meaning that effective adult stem cell research can continue to thrive in Louisiana," concluded Bordlee. (lifenews.com)
  • Rep. Beard had pointed out that a total human cloning ban does not impede research, as his opponents, including Senator Hines, have accused. (lifenews.com)
  • During debate on his bill, Beard stated that opponents of his bill place a 'false hope' in embryonic stem cell research. (lifenews.com)
  • As of yet no useful embryonic stem cell lines have been created, and all breakthroughs in stem cell research have been done with adult stem cells, which do not require the destruction of human life. (lifenews.com)
  • In January 2006, Hwang's home research institution, Seoul National University, delivered a damning report about Hwang's work on cloned human embryos, concluding it was all based on fraudulent data. (nature.com)
  • A chronology of Woo Suk Hwang's stem-cell research. (nature.com)
  • Scientists, many of whom are sold on utilitarian-based ethical analysis, try to downplay the issue of human life in stem-cell research. (catholicnewsagency.com)
  • And yet, all of us would be appalled at the idea of terminating their lives so we could harvest their tissues or organs in order to save others," she says, in reference to the common utilitarian argument that embryonic stem-cell research is valid in an effort to find cures that could save people's lives. (catholicnewsagency.com)
  • While some observers disagree with any use of embryos for scientific research, the overall position taken by the Assisted Human Reproduction Act seeks to maintain respect for human life and its transmission," she says in her conclusion. (catholicnewsagency.com)
  • Not only that, but poor Eve, who I believe is a full human being with a soul, will be a research subject all her life, however long that is. (probe.org)
  • He is the co-author of the book The Natural Limits to Biological Change , served as general editor of Creation, Evolution and Modern Science , co-author of Basic Questions on Genetics, Stem Cell Research and Cloning (The BioBasics Series) , and has published numerous journal articles. (probe.org)
  • Its new frontier is embryonic stem-cell and human cloning research. (lifenews.com)
  • STEM CELL RESEARCH is a very controversial topic in today's time. (ipl.org)
  • Stem cell research is not worth supporting. (ipl.org)
  • Advocates of stem cell research believe that the cells are not equivalent to human life because it is inside the womb even facing the fact that the start of a human life is in the moment of conception. (ipl.org)
  • While many people say the use of the cell research is a way to advance medical knowledge and expand treatments, there is no guarantee that the treatments will work. (ipl.org)
  • In recent years, several competing viewpoints have emerged about embryonic stem cell research. (ipl.org)
  • All of this debate raises an important question, Should embryonic stem cell research be conducted for treatment of present and future diseases? (ipl.org)
  • On the other hand, people who believe that embryonic stem cell research creates means of curing diseases reply that the research should be conducted. (ipl.org)
  • Embryonic stem cell research "uses special cells found in three-to-five day old human embryos to seek cures for a host of chronic disease" (PRC). (ipl.org)
  • The South Korean government has established an international stem cell research program with scientists in the United States and Britain. (voanews.com)
  • The collaboration gives U.S. researchers a way to overcome funding restrictions imposed by the Bush administration and participate in stem cell research. (voanews.com)
  • The project, called the World Stem Cell Hub, is headquartered at Seoul National University, where researchers led by Hwang Woo-Suk have been in the vanguard of stem cell research. (voanews.com)
  • According to the English-language newspaper South Korea Herald , the Ministry of Health and Welfare says the new World Stem Cell Hub combines South Korean expertise in stem cell research with broader U.S. and European knowledge of diseases. (voanews.com)
  • U.S. stem cell research has lagged because of Bush administration funding restrictions. (voanews.com)
  • The government, the country's largest source of research grants, provides money only for study on stem cells obtained before August, 2001, when President Bush announced this restriction. (voanews.com)
  • I applaud what they are doing, but I regret that the United States is falling farther behind in world leadership in scientific research generally and specifically on stem cell research,' said Mr. Specter. (voanews.com)
  • News reports quote South Korean President Roh Moo-hyun as saying that his government will try to resolve the ethical issues surrounding stem cell research so that the scientists can continue their work. (voanews.com)
  • It reportedly has access to 7,200 human eggs for its research. (bioedge.org)
  • The director of the lobby group Australians for Ethical Stem Cell Research, David van Gend, criticised the issuing of the licence. (bioedge.org)
  • He said cloning research was no longer necessary because of recent advances in stem cell science. (bioedge.org)
  • Great Iranian Muslim scholars netics, stem cell research, and organ trans- laid huge emphasis on teaching and practis- plantation are some of the medical issues ing ethics. (who.int)
  • Recently, research has increased in the area of transplanting embryonic cells across species and growing kidneys and endocrine pancreas cells in situ. (medscape.com)
  • 9,10] Organs from pigs have been the focus of much of the research in xenotransplantation, in part because of the public acceptance of killing pigs and the physiologic similarities between pigs and human and nonhuman primates. (medscape.com)
  • Pereira's research also involves reprogramming skin cells into dendritic cells, which are the sentinels of the immune system. (lu.se)
  • Recent news of an impending clinical cell transplantation trial in Parkinson's disease using parthenogenetic stem cells as a source of donor tissue have raised hopes in the patient community and sparked discussion in the research community. (lu.se)
  • Help us to be faithful to this sacred trust so that we may protect and promote the dignity of every human life from the very moment of conception, particularly the tiniest humans in the embryonic stage of human development who are so often forgotten by society & used by modern science. (archdiocese-no.org)
  • the right to religious freedom has its foundation in the very dignity of the human person as this dignity is known through the revealed word of God and by reason itself. (archdiocese-no.org)
  • This leads to manipulation and abuses gravely injurious to human dignity. (archdiocese-no.org)
  • To create embryos with the intention of destroying them, even with the intention of helping the sick, is completely incompatible with human dignity, because it makes the existence of a human being at the embryonic stage nothing more than a means to be used and destroyed. (archdiocese-no.org)
  • The use of the technique of nuclear transfer for reproduction of human beings is surrounded by strong ethical concerns and controversies and is considered a threat to human dignity. (who.int)
  • General Assembly the adoption of a declaration on human cloning by which Member States were called upon to prohibit all forms of human cloning inasmuch as they are incompatible with human dignity and the protection of human life. (who.int)
  • This technique is surrounded by strong ethical concerns and is considered a threat to human dignity. (who.int)
  • In short, the remaining ethical barriers that preserve human dignity and God's rights in Creation are steadily coming down. (lifenews.com)
  • It is important in the pursuit of progress to not undermine human dignity, and there is a line that can be drawn between progress and human dignity,' she noted. (voanews.com)
  • Michael Cook edits BioEdge, a bioethics newsletter, and MercatorNet, an on-line magazine whose focus is human dignity. (bioedge.org)
  • The U.S. Food and Drug Administration (FDA) has approved the world's first human clinical trial of a therapy involving embryonic stem cells, a move that has been condemned by the Vatican as "unacceptable. (womenofgrace.com)
  • This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Human CD138 Positive Selection Kit II (Catalog #1877) and EasySep™ Human Whole Blood and Bone Marrow CD138 Positive Selection Kit II (Catalog #17887). (stemcell.com)
  • Embryonic stem cells come from embryos, embryonic germ cells from testes, and adult stem cells can come from bone marrow. (cbc.ca)
  • The etiology of bone marrow failure (BMF) includes defective stem/progenitor cells and/or stroma/accessory cells/growth factors, as well as deficient nonspecific nutrients or, as in the case of acquired aplastic anemia, immune-mediated abnormalities. (medscape.com)
  • Inherited bone marrow failure syndromes (IBMFS) are usually the result of intrinsic stem cell/progenitor defects. (medscape.com)
  • Aplastic anemia is a disorder of the hematopoietic stem cell that results in a loss of blood cell precursors, hypoplasia or aplasia of bone marrow, and cytopenias in two or more cell lines (red blood cells, white blood cells, and/or platelets). (msdmanuals.com)
  • Hematopoietic stem cell transplantation (bone marrow, cord blood, or peripheral blood stem cells) may cure aplastic anemia and prevent myelodysplastic syndrome or leukemia. (medscape.com)
  • When the cloning process is used in this way, to produce a living duplicate of an existing animal, it is commonly called reproductive cloning. (eurostemcell.org)
  • In most countries, it is illegal to attempt reproductive cloning in humans. (eurostemcell.org)
  • 2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
  • 3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
  • 7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
  • 3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
  • CD14 is also found on tissue macrophages, Langerhans cells, and dendritic cells. (stemcell.com)
  • In a study published in the online journal Nature on March 1, 2009, Canadian researches described a new method for generating stem cells from adult human tissue. (cbc.ca)
  • Cloning describes the processes used to create an exact genetic replica of another cell, tissue or organism. (medlineplus.gov)
  • Researchers hope to use these cells to grow healthy tissue to replace injured or diseased tissues in the human body. (medlineplus.gov)
  • Researchers value the cells for their ability to replicate quickly and turn into any kind of human tissue. (christianitytoday.com)
  • Stem cells are the basic, undifferentiated cells in embryos that can develop into any kind of tissue. (voanews.com)
  • WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)
  • Note: Please read The Little Lamb That Made a Monkey of Us All for the author's comments on the news of a successful lamb cloning (March 7, 1997). (probe.org)
  • There are no international laws governing the use of cells and embryos, but scientists said a tough regulatory climate - like that in force in the UK - could prevent such abuses or misunderstandings. (bbc.co.uk)
  • Scientists have been all abuzz in the last few years over stem cells - cellular magicians that promise to dazzle and amaze. (cbc.ca)
  • Scientists say embryonic stem cells are the most useful type because they have the potential to become any type of cell within the body. (cbc.ca)
  • Scientists are fascinated by the ability of stem cells to become any type of cell. (cbc.ca)
  • Scientists announced this week that they have successfully produced embryonic stem cells by transferring the DNA of human skin cells into unfertilized human eggs to produce embryos, a technique the Church considers to be an abuse of human life. (womenofgrace.com)
  • Scientists at Stanford University in California have been able to coax embryonic stem cells into becoming eggs and sperm, which could one day lead to the creation of children through entirely artificial means. (womenofgrace.com)
  • British scientists are hailing the recent creation of human sperm cells that they believe could revolutionize fertility treatment. (womenofgrace.com)
  • 1. Cloning is an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. (who.int)
  • Scientists produced embryonic stem cells from the DNA of one person combined with a human donor egg. (technologyreview.com)
  • In 2013, scientists reported a successful SCNT procedure by modifying the protocol for specific human oocyte biology. (news-medical.net)
  • South Korean researchers would travel regularly to the labs to perform the complex task of creating embryos outside the womb and extracting new stem cell lines American, British, and other scientists could use for experiments on cures. (voanews.com)
  • Scientists say the old stem cell lines deteriorate and new ones are needed to advance work in this area. (voanews.com)
  • Chinese scientists have successfully created chimeric embryos containing a combination of human and pig cells. (bioedge.org)
  • A cloning pioneer regarded as a hero in his South Korean homeland has resigned and apologised for using human eggs from his own researchers. (bbc.co.uk)
  • Researchers there are working on technology that induces human skin cells to change into the kind of stem cells that have been created by embryos. (cbc.ca)
  • However, researchers at the Harvard Stem Cell Institute say reprogrammed cells won't eliminate the need or value of studying embryonic stem cells. (cbc.ca)
  • The stem cells could be studied in the laboratory to help researchers understand what goes wrong in diseases like these. (eurostemcell.org)
  • The groups argue that rather than waste embryos that will be destroyed along with their stem cells, researchers should use them to help save those whose lives are being cut short by disease. (christianitytoday.com)
  • Two other independent researchers, Severino Antinori (an Italian working in an undisclosed Muslim country) and Panos Zavos (from Lexington, Kentucky) have also been hinting at human cloning success and suggesting that a birth will be announced soon. (probe.org)
  • This incredibly high 50% success rate for human cloning leaves most researchers believing that either this isn't really a clone or they simply aren't revealing all the other failures. (probe.org)
  • Researchers have determined that several steps in the protocol were critical for human cellular reprogramming. (news-medical.net)
  • In humans, CD38 is expressed by the majority of hematopoietic cells at levels which vary according to the differentiation and activation status of the cells. (stemcell.com)
  • Derivation and differentiation of haploid human embryonic stem cells. (nature.com)
  • Aim: To detect the expression of molecules associated with Notch signaling pathway in stem cells from human exfoliated deciduous teeth (SHED) cultured in specific differentiation medium, namely, keratinocyte growth medium (KGM). (bvsalud.org)
  • Notch-1, Jagged-1, Jagged-2, and stem cell marker Nanog are expressed in SHED cultured in KGM which may be involved in the differentiation into epithelial-like cells in human dental pulp tissues. (bvsalud.org)
  • Since the Notch signaling pathway molecules play an important role in differentiation of epithelial cells, it is important to identify the presence of notch signaling molecules in SHED during the process of cell differentiation. (bvsalud.org)
  • The Notch signaling pathway provides important intercellular signaling mechanisms essential for cell fate specification and it regulates differentiation and proliferation of stem or progenitor cells by para-inducing effects 3-4 . (bvsalud.org)
  • Notch signaling pathway is also involved in the regulation of epithelial cell differentiation in various tissues 5-6 . (bvsalud.org)
  • Eve was delivered by Caesarian section from her twin sister (the woman who donated the nuclear genetic material from which she was cloned also served as the surrogate mother). (probe.org)
  • No objective, even though noble in itself, such as a foreseeable advantage to science, to other human beings or to society, can in any way justify experimentation on living human embryos or foetuses, whether viable or not, either inside or outside the mother's womb. (archdiocese-no.org)
  • By learning more about these topics, you will begin to see how the Church teaching matches up to God's plan and design for human beings. (catholicscomehome.org)
  • Creating embryonic stem cells and creating human beings for the purpose of destroying them for science crosses that line in my opinion. (voanews.com)
  • Professor Hwang Woo-suk was chairman of the World Stem Cell Hub, which opened this month, based in Seoul. (bbc.co.uk)
  • Earlier this month Gerald Schatten, a prominent American colleague of Dr Hwang, broke off their collaboration saying he was concerned by the way the group procured human eggs. (bbc.co.uk)
  • Lee Byeong-chun and Kang Seung-keun were accused of faking the outcome of studies on cloning human stem cells while working with Hwang. (asianews.it)
  • The South Korean stem-cell researcher Woo Suk Hwang has been at the centre of one of the largest investigations of scientific fraud in living memory. (nature.com)
  • The rapidly emerging "regenerative" field of medicine is relying heavily on the use of ethically obtained stem cells. (flfamily.org)
  • WHA50.37, which states "the use of cloning for the replication of human individuals is ethically unacceptable and contrary to human integrity and morality. (who.int)
  • The concept was pioneered a century ago, when transplanting human organs was considered ethically controversial. (medscape.com)
  • Somatic base substitution mutation rates in intestinal epithelial cells were elevated 2 to 4-fold in all individuals, except for one showing a 31-fold increase, and were also increased in other tissues. (bvsalud.org)
  • Induction of stem-like cells with malignant properties by chronic exposure of human lung epithelial cells to single-walled carbon nanotube s. (cdc.gov)
  • Methods: Non-tumorigenic human lung epithelial cells were chronically exposed to well-dispersed SWCNT for a period of 6 months at the physiologically relevant concentration of 0.02 mu g/cm(2) surface area dose. (cdc.gov)
  • Results: We demonstrated for the first time the existence of CSC-like cells in all clones of chronic SWCNT-exposed lung epithelial cells. (cdc.gov)
  • If cloning were to be done for reproduction, this would impose on the resulting individual a predetermined genetic identity, subjecting him - as has been stated - to a form of biological slavery, from which it would be difficult to free himself. (archdiocese-no.org)
  • The copied material, which has the same genetic makeup as the original, is referred to as a clone. (medlineplus.gov)
  • These stem cells are genetically matched to the donor organism, holding promise for studying genetic disease. (eurostemcell.org)
  • A clone is an organism that is a genetic copy of an existing one. (who.int)
  • A third view says that cloning will provide for the possibility of improvement by giving birth to children who are free of birth defects, because when any two people create a child through sex there is the possibility for genetic defects. (bartleby.com)
  • However, since clones are the exact replicas of someone already alive, their genetic dispositions will have already surfaced. (bartleby.com)
  • Wutz, A. Haploid mouse embryonic stem cells: rapid genetic screening and germline transmission. (nature.com)
  • Genetic modification and screening in rat using haploid embryonic stem cells. (nature.com)
  • Embryonic stem cell transplants have been an ethical, social, and legal controversy since the first successful transplant of human stem cells in 1998. (ipl.org)
  • A new controversy is brewing over government backing of Ebola vaccines that are using aborted fetal cell lines even though vaccines developed from moral alternatives are just as effective. (womenofgrace.com)
  • They are in an early stage of development and have the ability to become any type of cell to form skin, bones, organs or other body parts. (cbc.ca)
  • Cloning of human cells is a technology that holds the potential to cure many diseases and provide a source of exactly matched transplant tissues and organs. (news-medical.net)
  • Xenotransplantation involves the transplantation of nonhuman tissues or organs into human recipients. (medscape.com)
  • In light of the lack of supply of human organs for transplantation, several alternatives have been investigated and debated. (medscape.com)
  • Additionally, organs from animal sources could be transplanted into patients currently excluded from the human organ transplantation list. (medscape.com)
  • Finally, most patients perceive xenotransplantation as an acceptable bridge to transplantation of human organs in life-threatening situations. (medscape.com)
  • Human cloning science offers the possibility that stem cells harvested from cloned embryos could be used to treat diseases like Parkinson's, diabetes and heart disease. (bbc.co.uk)
  • These cells have been sought after as potential therapies for diseases ranging from heart disease to Parkinson's to cancer. (news-medical.net)
  • 4] Porcine skin has been grafted onto burn patients,[5] and pig neuronal cells have been transplanted into patients with Parkinson (Parkinson's) disease and Huntington (Huntington's) disease. (medscape.com)
  • Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016? (lu.se)
  • Based on discussions held by a global collaborative initiative on translation of stem cell therapy in Parkinson's disease, we have identified a set of key questions that we believe should be addressed ahead of every clinical stem cell-based transplantation trial in this disorder. (lu.se)
  • In this article, we first provide a short history of cell therapy in Parkinson's disease and briefly describe the current state-of-art regarding human stem cell-derived dopamine neurons for use in any patient trial. (lu.se)
  • Stem cell-based therapies for Parkinson's dis- ogy company International Stem Cell Corporation ease (PD) are rapidly moving towards clinical trials. (lu.se)
  • The report notes that the AAR, which bills itself as the leading citizen advocacy organization for improving the health of older Americans, "also happens to receive funding from private-sector biotechnology companies that have a financial stake in the outcome of the stem-cell debate, including Geron," the for-profit corporation that isolated embryonic stem cells in 1998. (christianitytoday.com)
  • Margaret Somerville, founding director of the McGill Centre for Medicine, Ethics and Law at McGill University in Montreal, makes her case from a purely academic and secular perspective in a comment published in the National Post last week, called "The ethics of stem cells. (catholicnewsagency.com)
  • The right to have children is understood in very different ways and people's ethics and values are put to the test each and everyday when they find out they not only must take care of themselves but the lives of another human being. (bartleby.com)
  • This baby and the others to follow are human experiments with high odds to develop life-threatening complications. (probe.org)
  • It is unspeakable that we should continue this project of creating living human embryos with the sole purpose of destroying them when the compelling justification for such experiments has gone,' Dr van Gend said. (bioedge.org)
  • Carrie Gordon Earl, bioethics analyst for Focus on the Family, said, "This is about nonconsensual human experimentation. (christianitytoday.com)
  • Indeed, some observers believe the demand for stem cells is dangerously close to spawning a huge commercial industry around the sale of and experimentation on human embryos. (christianitytoday.com)
  • Although the simple use of the word 'clone' may have negative connotations, many people have resigned themselves to the idea of cloning cows that produce more milk or using a cloned mouse for use in controlled experimentation. (bartleby.com)
  • For example, stem cells could be generated using the nuclear transfer process described above, with the donor adult cell coming from a patient with diabetes or Alzheimer's. (eurostemcell.org)
  • By transferring adult cell DNA into an embryonic stem cell, it is possible to create a line of immortal embryonic cells that are able to develop into any type of adult cell, genetically identical to the donor. (news-medical.net)
  • Those were spindle removal, donor cell fusion, and cytoplast activation. (news-medical.net)
  • The mitochondrial DNA of the stem cells, however, matched the donor egg's mitochondrial DNA. (news-medical.net)
  • The adult cell nuclei were transferred into metaphase-II stage human oocytes, producing a karyotypically normal diploid embryonic stem cell line from each of the adult male donor cells. (news-medical.net)
  • Reprogramming skin cells to blood stem cells could potentially provide an unlimited source of cells for transplantation to patients with blood disorders. (lu.se)
  • The HIT2 antibody reacts with CD38, an ~45 kDa type II transmembrane glycoprotein expressed by many cell types, especially leukocytes. (stemcell.com)
  • 4. Dilute the antibody 1:10 in 1× PBS, and stain the cells by adding 50 µl of the diluted antibody conjugate to each well and incubating for 1 hour at RT. (bdbiosciences.com)
  • The Ethical Debate Concerning Cloning In the year that has elapsed since the announcement of Dolly's birth, there has been much discussion of the ethical implications of cloning humans. (bartleby.com)
  • Do our only cloned primates come from the lab of Woo Suk Hwang's colleague? (nature.com)
  • The researcher claimed he had created stem cell lines from cloned human embryos. (asianews.it)
  • President Bush, saying he wanted to "proceed with great care," announced in a national address on August 9 that he would allow federal funding of an existing 60 stem-cell lines but would not permit tax dollars to pay for the destruction of any additional human embryos. (christianitytoday.com)
  • Do Ebola Vaccines Need to Use Embryonic Stem Cell Lines? (womenofgrace.com)
  • They derived several human embryonic stem cell lines from these cloned embryos whose DNA was an exact match to the adult cell that donated the DNA. (news-medical.net)
  • Congress is moving ahead with legislation to overturn Mr. Bush's ban and allow new stem cell lines to be created with government money. (voanews.com)
  • But SCNT can also be used to clone human cells for transplant or other therapies. (news-medical.net)
  • In humans, a major roadblock in achieving successful SCNT leading to embryonic stem cells has been the fact that human SCNT embryos fail to progress beyond the eight-cell stage. (news-medical.net)
  • This was the first successful reprogramming of human somatic cells into embryonic stem cells using a cloning technique, SCNT. (news-medical.net)
  • Another successful attempt at human SCNT was made using cells from two adult males. (news-medical.net)
  • It's adequately funded, but our main work is on finding therapies for human diseases. (medscape.com)
  • The cells carry the potential to cure neurological diseases, diabetes, and many other illnesses. (christianitytoday.com)
  • The diseases and treatments that could come from giving up a human life are not worth it. (ipl.org)
  • While at the hospital she was unaware that the doctors there were experimenting on her taking cell samples from her body, to help find a resolution to multiple diseases. (ipl.org)
  • But previous approaches required the use of viruses to deliver the four genes needed to activate the cell and accomplish that task. (cbc.ca)
  • hPSC-enriched essential genes mainly encode transcription factors and proteins related to cell-cycle and DNA-repair, revealing that a quarter of the nuclear factors are essential for normal growth. (nature.com)
  • Overall, we have constructed an atlas of essential and growth-restricting genes in hPSCs, revealing key aspects of cellular essentiality and providing a reference for future studies on human pluripotency. (nature.com)
  • Fig. 2: Analysis of cell-essential genes. (nature.com)
  • The precise pathophysiology of inherited single cell and multilineage cytopenias has not been elucidated despite the identification of many of the genes mutated in these disorders. (medscape.com)
  • This sparked Filipe Pereira's curiosity about the human body, and he put aside his plans to study architecture, choosing instead biology and later pursue a doctorate in epigenetics. (lu.se)
  • Haematopoietic stem cells or multipotent progenitors (HSC/MPPs) accumulated a mean of 17 mutations per year after birth and lost 30 base pairs per year of telomere length. (bvsalud.org)
  • Stem cells from human exfoliated deciduous teeth (SHED) are multipotent stem cells derived from the pulp tissues of extracted deciduous teeth 1 . (bvsalud.org)
  • South Korea's health ministry also admitted that other women were paid thousands of dollars for their eggs, though this took place without Dr Hwang's knowledge and before a new law outlawed trading in human eggs. (bbc.co.uk)
  • Science retracted both articles after the SNU revealed that the studies were faked, and that the stem cells had not been genetically created but had come from donors' eggs. (asianews.it)
  • Cloning: Do we even need eggs? (nature.com)
  • The Food and Drug Administration (FDA) is delaying a bid by biotech company Geron Corp. to become the first to conduct human trials with embryonic stem cells, pending review of new studies. (womenofgrace.com)
  • RNA was reverse-transcribed to obtain the cDNA and then proceeded with PCR using specific primers for the Notch signaling pathway molecules (Notch1, Jagged-1, Jagged-2 and, Hes1) as well as stem cell marker (Nanog). (bvsalud.org)
  • These cells also displayed aberrant stem cell markers, notably Nanog, SOX-2, SOX-17 and E-cadherin. (cdc.gov)
  • Some argue that the possibility of mimicking stem cells without acquiring them from embryos, side-steps that moral dilemma. (cbc.ca)
  • In cancer patients dendritic cells may become dysfunctional or excluded from tumors. (lu.se)
  • Therefore, new ways are needed to reprogram other cells into immune cells with the same capacity as the "natural" dendritic cells. (lu.se)
  • By using skin cells as the starting cell-type, he managed to identify the three molecules needed to "program" dendritic cells in just nine days. (lu.se)
  • In the next step, he used the same molecules to reprogram cancer cells into dendritic cells. (lu.se)
  • Topics covered will include cell membrane structure and function, metabolism, cell motility and division, genome structure and replication, the regulation of gene expression and protein production, genotype to phenotype relationship, and basic principles of inheritance. (middlebury.edu)
  • Both crRNA-tracrRNA duplexes and sgRNAs can be used to target SpCas9 for multiplexed genome editing in eukaryotic cells 1 , 3 . (cdc.gov)