Human renal allograft. Medical search. Frequent questions

When analyzed in 45 kidney transplant recipients at the time of late for-cause biopsy, the T1/T2 ratio was independently associated with allograft dysfunction over the next 5 years. (whiterose.ac.uk)
Cytomegalovirus (CMV) prophylaxis may prevent CMV indirect effects in renal transplant recipients. (biomedcentral.com)
From November 2007 through April 2012, adult renal transplant recipients were randomized, in an open-label, single-center study, at a 1:1 ratio to 3-month prophylaxis with valganciclovir ( n = 60) or valacyclovir ( n = 59). (biomedcentral.com)
In contrast, DSBT given to backcrossed recipients expressing the RT1c/c (c/c) phenotype elicited a transient IgM response that switched to a very low IgG response and was associated with renal allograft acceptance. (duke.edu)
Analysis of IgG isotypes demonstrated that DSBT prevented production of IgG1 and IgG2a, and to a lesser extent IgG2b and IgG2c alloantibodies in c/c but not u/c renal allograft recipients. (duke.edu)
A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts. (medigraphic.com)
3. To what extent has recombinant human growth hormone (rhGH) been utilized in growth retarded recipients after transplantation and has its use resulted in accelerated post-transplantation growth? (emmes.com)
Prope tolerance, perioperative campath 1H, and low-dose cyclosporin monotherapy in renal allograft recipients. (ox.ac.uk)
The present study was designed to investigate the effects of this drug on human leukocyte(HLA) antibody production in general and donor-specific antibody (DSA) formation in particular in 154 recipients of renal allografts. (uni-regensburg.de)
PATIENTS AND METHODS: Renal allograft recipients were subdivided into three groups. (uni-regensburg.de)
CONCLUSION: The MMF reduces anti-HLA class I and II antibody production and consequently DSA production in renal allograft recipients. (uni-regensburg.de)
The presence of DSA in the serum of renal allograft recipients is associated with poorer graft function (higher serum creatinine and more rejection episodes). (uni-regensburg.de)
However, chronic allograft dysfunction in the form of bronchiolitis obliterans remains a major hurdle that threatens both the quality of life and long-term survival of the recipients. (ersjournals.com)
Dendritic cell deficiency associated with development of BK viremia and nephropathy in renal transplant recipients. (cdc.gov)
Association of interferon gamma gene polymorphisms with BK virus infection among Hispanic renal allograft recipients. (cdc.gov)
High-risk human papillomavirus in non-melanoma skin lesions from renal allograft recipients and immunocompetent patients. (granturieuropene.ro)
Post-transplantation anemia is common among renal transplant recipients (RTR). (medpharmres.com)
This case report describes two male renal transplant recipients who infected HPV B19 after kidney transplantation with severe anemia. (medpharmres.com)
In conclusion, when anemia develops rapidly and severely in renal transplant recipients in the absence of rejection and hemolysis, parvovirus B19 infection should be considered. (medpharmres.com)
Renal transplant recipients are up to 5 times more likely to develop malignant melanoma compared with the general population, [ 4 ] and those with melanoma are more likely to die of their disease. (medscape.com)
But are some renal transplant recipients more likely than others to develop malignant melanoma ? (medscape.com)
This large retrospective cohort analysis confirms that renal transplant recipients have a fivefold increased risk of developing malignant melanoma. (medscape.com)
In this context, renal transplant recipients should be monitored closely for suspicious or changing pigmented lesions, and routine total body skin exams (annual or biannual, depending on history and other risk factors) should be the standard of care. (medscape.com)
These study findings also raise a therapeutic challenge, because renal transplant recipients with melanoma need to be treated. (medscape.com)
As more renal transplant recipients develop cancer-including malignant melanoma-over time, these practical questions will need to be addressed. (medscape.com)

Renal biopsy remains the gold-standard for detecting allograft rejection but is associated with significant morbidity and mortality. (hindawi.com)
Several animal models of allograft rejection exhibit monocyte and macrophage infiltration in allograft tissue [ 13 - 17 ], and these cells have a central role in human chronic allograft damage [ 18 , 19 ]. (hindawi.com)
The recipient had a fever 8 days after receiving the renal allograft, and a biopsy of it showed acute rejection. (cdc.gov)
Donor-specific antibodies (DSA) are associated with acute kidney graft rejection, but their role in small bowel/multivisceral allograft remains unclear. (lww.com)
We carried out a prospective study to understand the impact of DSA in the setting of intestinal allograft rejection. (lww.com)
The clinical rejection episodes in allografts were significantly associated with the presence of DSA ( P =0.041).We obtained 291 biopsy samples from graft ileum and date-matched DSA assay reports. (lww.com)
Donor-specific blood transfusion (DSBT) in animals and humans can either promote subsequent renal graft survival or lead to sensitization and graft rejection. (duke.edu)
In F1 rats produced by mating PVG (RT1c), a low IgG alloantibody responder to transfused ACI (RT1a) blood, with 3 different high-IgG responders [W/F (RT1u), LOU (RT1u), and LEW (RT1l)], high IgG alloantibody production was found to be inherited as a dominant trait and associated with acute rejection of ACI renal allografts. (duke.edu)
DSBT given to offspring of (PVG x W/F)F1 rats backcrossed to W/F with either RT1u/c (u/c) or RT1u/u) (u/u) phenotype induced high-IgG-alloantibody responses that were associated with acute renal allograft rejection. (duke.edu)
The OKT3 antibody has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. (thermofisher.com)
The similarity between hyperacute rejection of ABO-incompatible allografts and xenografts initiated his xenotransplantation research. (gu.se)
Meier-Kriesche HU, Schold JD, Srinivas TR, Kaplan B. Lack of improvement in renal allograft survival despite a marked decrease in acute rejection rates over the most recent era. (medigraphic.com)
Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: a randomised multicentre study. (medigraphic.com)
Human CMV infection is controlled by T cell-mediated immunity and in immunosuppressed transplant patients it is associated with acute allograft rejection as well as chronic allograft vasculopathy. (aai.org)
CMV infects endothelial cells (EC) and it is thought that CMV-specific host immune responses to infected allograft EC contribute to rejection. (aai.org)
These results provide a mechanism by which CMV can exacerbate allograft rejection and suggest a novel function of EC-derived exosomes that could contribute in a more general manner to immune surveillance. (aai.org)
Allograft rejection often involves injury of graft endothelium lining both large and small vessels. (aai.org)
For many years, chronic allograft nephropathy (CAN) was used to describe the progressive loss of renal function in transplanted kidneys over time not related to acute rejection. (biomedcentral.com)
Beyond GWAS—Could Genetic Differentiation within the Allograft Rejection Pathway Shape Natural Immunity to COVID-19? (mdpi.com)
The most frequent causes are erythropoietin deficiency, acute allograft rejection, iron deficiency, hemolytic anemia, adverse effects of immunosuppressive therapy, and virus infection. (medpharmres.com)
Consecutively, C4d is a stable split product remnant of classical complement activation and an established marker of antibody-mediated acute renal allograft rejection. (samatashkhis.com)
Due to its proclivity for endothelium, this component can be detected in peritubular capillaries in both chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. (samatashkhis.com)

Her research program includes hyperpolarized 13C MR spectroscopic imaging (MRSI) to assess renal tumor aggressiveness and diffuse renal disease (nephropathy), as well as quantitative imaging in pancreatic cancer. (ucsf.edu)
The cause of late renal allograft loss, once known as chronic allograft nephropathy, has been renamed "interstitial fibrosis and tubular atrophy" (IF/TA) to reflect the histologic pattern seen on biopsy. (biomedcentral.com)
Polyomavirus BK nephropathy (PVBKN) is an important cause of allograft dysfunction in patients with kidney transplantation [ 1 ]. (biomedcentral.com)

Blood transfusions and renal allograft survival. (bmj.com)
Scholars@Duke publication: The association of enhancement of renal allograft survival by donor-specific blood transfusion with host MHC-linked inhibition of IgG anti-donor class I alloantibody responses. (duke.edu)
These findings demonstrate that the variable ability of DSBT to enhance renal allograft survival correlates with the inhibition of antidonor class I alloantibody responses of all IgG subclasses by a mechanism that is linked to host MHC. (duke.edu)
For example, in developing and developed countries alike, kidney transplantation not only yields survival rates and quality-of-life that are far superior to those obtained with other treatments for end-stage renal disease, such as haemodialysis, but is also less costly in the long run. (who.int)
Renal function and the mother's survival were followed until December 2002. (nih.gov)
Although kidney transplantation has been an important means for the treatment of patients with end stage of renal disease, the long-term survival rate of the renal allograft remains a challenge. (biomedcentral.com)
Identifying the mediators and factors that trigger IF/TA may be useful in early diagnosis and development of novel therapeutic strategies for improving long-term renal allograft survival and patient outcomes. (biomedcentral.com)
Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses. (immunetolerance.org)
After successful reduction of early complications, chronic allograft dysfunction has become the major obstacle to long-term survival. (ersjournals.com)

The role of monocytes and macrophages in chronic renal allograft damage has been well established [ 9 ]. (hindawi.com)
Monocytes and macrophages are known to play a role in chronic renal allograft damage [ 10 ] and are key promoters of fibrosis in other organs, such as the liver [ 11 , 12 ]. (hindawi.com)
Chronic renal failure leads to amenorrhea, and successful pregnancy is rare. (nih.gov)

Chronic allograft damage (CAD), characterised by interstitial fibrosis and tubular atrophy (IFTA), is the commonest cause of transplant failure following surgery [ 1 ]. (hindawi.com)
There is no imaging modality available to measure the development of graft fibrosis and current practice involves a biopsy when renal function deteriorates [ 8 ]. (hindawi.com)
Valganciclovir prophylaxis, as compared with valacyclovir, was associated with a reduced risk of moderate-to-severe interstitial fibrosis and tubular atrophy in patients after renal transplantation. (biomedcentral.com)
Interstitial fibrosis and tubular atrophy (IF/TA) describes the histologic characteristics of allograft destruction over time. (biomedcentral.com)

Current imaging techniques for monitoring allograft function involve the use of ultrasound to exclude ureteric obstruction or vascular compromise in the failing kidney. (hindawi.com)

To prove these hypotheses we plan an analysis of a large repository of human biopsy material from kidney transplants to elucidate and understand, in detail, the integrin-TGF-β-scarring pathway. (rotrf.org)
All these biopsy samples were evaluated with routine renal biopsy stains as well as IHC for SV40 (Simvian Virus 40) antigen. (biomedcentral.com)
Routine IHC study for SV40 in all transplanted kidney biopsy samples with new onset of allograft dysfunction, will enhance the diagnostic sensitivity of early stage disease detection. (biomedcentral.com)
Identification of human papillomavirus DNA in melanoma biopsy specimens of Greek population. (granturieuropene.ro)

Herein, we aim to further define B regulatory phenotype and determine whether B regulatory activity can serve as a prognostic marker for renal allograft dysfunction (graft loss or 2-fold fall in estimated glomerular filtration rate). (whiterose.ac.uk)
Again, the T1/T2 ratio was strongly and independently associated with allograft dysfunction over the ensuing 5 years. (whiterose.ac.uk)
In these clinically quiescent patients, a low T1/T2 ratio identified a 41-patient subgroup in which 35% developed allograft dysfunction, with 25% losing their allografts. (whiterose.ac.uk)
Chronic nephrotoxic effects of calcineurin inhibitors may be associated with late allograft dysfunction and reduced allograft half-life. (biomedcentral.com)
The patients who have presented with new onset of allograft dysfunction, at least 2 weeks after transplantation surgery, were included in our study. (biomedcentral.com)

Treatment is not recommended for subclinical anogenital or mucosal human papillomavirus (HPV) infection in the absence of coexistent dysplasia. (medscape.com)
CMV infection also promotes the development of chronic allograft vasculopathy (characterized by graft vessel arteriosclerosis) that underlies late graft failure ( 6 , 11 ). (aai.org)
On the initial stage of renal infection, characteristic viral inclusion bodies cannot be detected on routine morphologic study. (biomedcentral.com)
The clinical history and presentation of human papillomavirus (HPV) infection vary according to the anatomic area involved. (medscape.com)
One of the ethiopathogenic factors that cause skin carcinogenesis could be the infection with some genotypes of human papillomavirus HPV. (granturieuropene.ro)
Markers of cutaneous human papillomavirus infection in individuals with tumor-free skin, actinic keratoses and squamous cell carcinoma. (granturieuropene.ro)
Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck. (granturieuropene.ro)

These results have been applied in clinical practice to establish ABO-incompatible renal and liver transplantation programs in Gothenburg and Birmingham, UK. (gu.se)
resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver . (wikidoc.org)
IARC Monographs act entirely or largely by immuno- heart, liver, or lung) can be trans- carcinogenic to humans (Group 1). (who.int)
Solid organ transplantation, although lifesaving for patients with end-stage renal, liver, or heart disease, requires chronic immunosuppressive therapy that increases the risk for cancer, including lymphoma and skin cancer. (medscape.com)

Johnson RW, Kreis H, Oberbauer R, Brattstr m C, Claesson K, Eris J. Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure. (medigraphic.com)

Skin allografts or amnion grafts are effective burn-wound dressings and are within the reach of low- or medium-income countries. (who.int)

This idea has recently been challenged by a study showing that increased levels of resistin in people with chronic kidney disease are associated with lowered renal function and inflammation, but not with insulin resistance. (wikidoc.org)
The mechanisms leading to IF/TA in the transplanted kidney include inflammation, activation of renal fibroblasts, and deposition of extracellular matrix proteins. (biomedcentral.com)

Both SPKTx mothers have maintained normal renal and pancreatic allograft function 42 and 62 months postdelivery. (nih.gov)

Sirolimus-based therapy following early cyclosporine withdrawal provides significantly improved renal histology and function at 3 years. (medigraphic.com)
Sirolimus-based therapy with or without cyclosporine: long-term follow-up in renal transplant patients. (medigraphic.com)
It is evident that both cyclosporine and tacrolimus can cause renal and systemic vasoconstriction through increased release of endothelin-1, activation of the renin-angiotensin system, increased production of thromboxane A 2 , and decreased production of vasodilators such as nitric oxide and prostacyclin [ 7 ]. (biomedcentral.com)

Strategies to improve long-term outcomes after renal transplantation. (medigraphic.com)

Human transitional B cells express relatively high IL-10 and low TNF-α levels, which correlate with B regulatory activity in vitro. (whiterose.ac.uk)
MICA engagement by human Vgamma2Vdelta2 T cells enhances their antigen-dependent effector function. (bdbiosciences.com)
and the exploration of techniques to expand human natural killer cells in a closed-culture setting for treatment of minimal residual disease in leukemia. (umaryland.edu)
1. Injury in renal allografts causes increased epithelial stress which induces expression of TGF-β-activating αv integrins in epithelial cells, leading to increased activation of latent TGF-β, which leads to epithelial de-differentiation and scarring. (rotrf.org)
1 This includes human cells for transplantation such as haematopoietic stem cells from bone marrow, peripheral blood or cord blood. (who.int)
Human CMV grows only in human cells and replicates best in human fibroblasts. (medscape.com)
Staining of normal human peripheral blood cells with Anti-Human CD19 FITC (Product # 11-0199-42) and Mouse IgG2a K Isotype Control Super Bright 702 (Product # 67-4724-82) (left) or Anti-Human CD3 Super Bright 702 (right). (thermofisher.com)
Applications Tested: This OKT3 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. (thermofisher.com)
During more recent years, his reseach has been conducted in the field of regenerative medicine, focussed on antigen expression and immune recognition of human embryonic stem cells and bioartificial heart valves, the latter tissues being of animal origin. (gu.se)
Human milk is a very complex fluid with a multitude of proteins, cells, and other components. (unu.edu)
Human vascular endothelial cells (EC) 3 display both class I and class II MHC molecules and are directly recognized by CD8 + and CD4 + alloreactive T cells, respectively ( 12 , 13 , 14 , 15 ). (aai.org)
After immunosuppression, following transplantation, the virus activates, replicates, and damages urothelial cells as well as renal parenchymal tubules. (biomedcentral.com)
The immune system is comprised of highly specialized q The findings and conclusions in this report are those of the authors and cells, tissues, and organs that give the human body the do not necessarily represent the views of the Agency for Toxic Substances and Disease Registry. (cdc.gov)
Chronic immunosuppression increases the risk for cancer through multiple pathways, including impaired immune surveillance of tumor cells and reduced clearance of oncogenic viruses, such as human papillomavirus . (medscape.com)

Klapholz-Brown Z, Walmsley GG, Nusse YM, Nusse R, Brown PO "Transcriptional program induced by wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments. (openwetware.org)

He was a visiting INSERM researcher at the Institute de Biologie, Universite de Nantes, Nantes, France, in 1991-2, and visiting professor and consultant surgeon in renal transplantation surgery at Queen Elizabeth Hospital, Birmingham, UK, in 2003-4. (gu.se)

The number of human tissue transplants is increasing in both developed and developing countries, but global data on this form of transplantation are less complete. (who.int)
In Europe, hundreds of thousands of tissue transplants are performed each year, and in 1999 an estimated 750 000 people in the United States of America received human tissue, twice as many as in 1990. (who.int)
Resistin also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) is a cysteine -rich adipose-derived peptide hormone that in humans is encoded by the RETN gene . (wikidoc.org)

In August 1986, a cadaveric organ donor was found positive for antibody to the human immunodeficiency virus (HIV) by both enzyme immunoassay (EIA) and Western blot methods after some of the donated organs had been transplanted. (cdc.gov)

In addition, we will use mouse models in which the crucial function of integrins at the beginning of this fatal pathogenetic chain towards scarring is abrogated, to test whether interventions against integrins represent a potential therapeutic option in patients with progressive scarring in renal transplants. (rotrf.org)
Human clinical trials that investigate possible MDSC modulators are highlighted, and therapeutic strategies to leverage MDSC biology in bladder cancer immunotherapy are outlined. (iospress.com)

In the present study, we aimed to study the association of human leukocyte antigen (HLA) with familial and non-familial SSc patients [limited cutaneous SSc (lcSSc) and diffuse cutaneous SSc (dcSSc)] from North India. (bvsalud.org)
Human parvovirus B19 (HPV B19) can cause persistent viremia and erythropoietin-resistant erythroid aplasia in immunosuppressed patients. (medpharmres.com)
Il s'agit d'une étude transversale, monocentrique et descriptive, durant 12 mois, incluant les patients âgés d'au moins 18 ans admis en réanimation polyvalente pour un sepsis ou choc septique. (bvsalud.org)
Deaths occurred beyond 24 hours of hospitalization (75%), in patients with comorbidities (65.6%), peritonitis (59.4%), hemodynamic (81.2%) and renal (75%) failures. (bvsalud.org)

This article discusses the alloimmune-dependent and -independent risk factors for bronchiolitis obliterans, the current understanding of the pathogenesis of bronchiolitis obliterans based on results of animal and human studies, the clinical staging of the complication, strategies that may contribute to the prevention and/or early detection of bronchiolitis obliterans, and suggestions for future research. (ersjournals.com)

All mothers survived the pregnancy and retained allograft function. (nih.gov)
What is the impact of age, pubertal growth, gender, transplant history, donor source and allograft function on growth after transplantation? (emmes.com)
Its pathogenesis has not been fully elucidated and existing therapy is not effective in improving renal transplant function. (biomedcentral.com)

Native kidneys and skeletal muscle were imaged as reference tissues and renal explants analysed by histology and electron microscopy. (hindawi.com)

Studies of human kidneys/urinary tract revealed that human kidney contained a new type of blood group A structure. (gu.se)

This study aimed to compare the efficacy of valganciclovir and valacyclovir prophylaxis for CMV after renal transplantation with the focus on chronic histologic damage within the graft. (biomedcentral.com)

Detection of alpha- and beta- human papillomavirus in cutaneous melanoma: a matched and controlled study using multiplex PCR combined with DNA microarray primer. (granturieuropene.ro)
The human papillomavirus family and its role in carcinogenesis. (granturieuropene.ro)
Human papillomavirus in basal cell fingertip cancer - a pilot study. (granturieuropene.ro)
Cutaneous squamous cell carcinoma and human papillomavirus: is there an association? (granturieuropene.ro)
Detection of mucosal type human papillomavirus in cutaneous squamous cell carcinoma in Iran. (granturieuropene.ro)
Human papillomavirus and rising oropharyngeal cancer que pastilla es para oxiuros in the United States. (granturieuropene.ro)

The 6D4 monoclonal antibody specifically binds to the human MHC class I polypeptide-related sequence A (MICA, aka PERB11.1) and B (MICB. (bdbiosciences.com)
Description: The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. (thermofisher.com)
This antibody has a high affinity for CEA and shows no detectable reactivity to nonspecific cross-reacting antigen (NCA), biliary glycoprotein (BGP) and human polymorphonuclear leucocytes. (samatashkhis.com)
anti-human CEA rabbit polyclonal antibody purified from serum and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide. (samatashkhis.com)
anti-human Caspase 3 rabbit polyclonal antibody purified from rabbit anti-serum by Protein A chromatography. (samatashkhis.com)

Experiencia mexicana con el uso de sirolimus en trasplante renal. (medigraphic.com)
La sobrevida de los receptores de trasplante renal ha mejorado a trav s de los a os, sirolimus (SRL) ha probado ser ben fico en t rminos de funci n renal, histolog a y sobrevida del injerto. (medigraphic.com)

The appearance of DSA were preformed (n=5, anti-human leukocyte antigen class II=3, anti-class I and II=2), de novo (n=4, 15.25±4.72 days after transplantation, anti-class II=1, and anti-class I and II=3) and never (n=6). (lww.com)

The differences in the level and isotype of IgG alloantibody responses found in sera of DSBT-pretreated backcross rats of u/c and c/c phenotypes were also present in allograft eluates and splenocyte cultures. (duke.edu)

Human CEA isolated from hepatic metastasis of colon adenocarcinoma. (samatashkhis.com)
Renal (71.4%), hepatic (69.6%) and hemodynamic (62.5%) failures were the most common. (bvsalud.org)

Using a rat renal allograft model, we have examined whether the effects of DSBT on renal allograft outcome and IgG alloantibody responses are linked to the host MHC. (duke.edu)

We tested what native features have been preserved with a new culture protocol for adult human RPE. (arvojournals.org)
We cultured RPE from adult human eyes. (arvojournals.org)
Confluent monolayers of adult human RPE cultures exhibit characteristics of native RPE. (arvojournals.org)

A man with end-stage renal disease received the donated kidney that was transplanted. (cdc.gov)
What have 20 years of data from the North American Pediatric Renal Transplant Cooperative Study taught us about growth following renal transplantation in infants, children, and adolescents with end-stage renal disease? (emmes.com)
Compensation, and Liability Act, Section 104(3) (Super on the most sensitive endpoints identified in humans or ani fund), the Agency for Toxic Substances and Disease mals. (cdc.gov)

2016) A non-human primate model of radiation-induced cachexia. (umaryland.edu)

Registry (ATSDR) is mandated to address the potential tified the immune system as the most sensitive organ system health impact of hazardous substances to human health for a number of chemicals. (cdc.gov)

Rubins KH, Hensley LE, Wahl-Jensen V, Daddario Dicaprio KM, Young H, Reed DS, Jahrling PB, Brown PO, Relman DA, Geisbert TW "The temporal program of peripheral blood gene expression in the response of non-human primates to Ebola hemorrhagic fever. (openwetware.org)

Anatomy13

Organisms10

Diseases31

Chemicals and Drugs35

Analytical, Diagnostic and Therapeutic Techniques and Equipment45

Phenomena and Processes11

Disciplines and Occupations1

Information Science2

Named Groups2

Health Care13

Recipients25

Rejection22

Nephropathy3

Survival9

Chronic renal3

Fibrosis4

Monitoring allograft function1

Biopsy4

Dysfunction5

Infection7

Liver4

Improved renal function1

Grafts1

Inflammation2

Pancreatic1

Cyclosporine3

Outcomes1

Cells14

Fibroblasts1

Transplantation surgery1

Tissue3

Methods1

Therapeutic2

Patients4

Clinical1

Function3

Electron microscopy1

Kidneys1

Histologic1

Papillomavirus6

Antibody5

Sirolimus2

Antigen1

Isotype1

Hepatic2

Outcome1

Adult3

Disease3

20161

Organ1

Primates1