Human receptor protein tyrosine kinases. Medical search. Frequent questions

Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. (wikipedia.org)
T794A-expressing human umbilical vein endothelial cells formed significantly shorter tubes with fewer branches in three-dimensional Matrigel cultures, but did not alter Tie1 or Tie2 tyrosine phosphorylation or downstream signaling. (cusabio.com)
Upon immobilization sAxl advertised cell migration and induced the phosphorylation of Axl and phosphatidylinositol 3-kinase. (exposed-skin-care.net)
Phosphorylation of EGFR at certain residues is also mediated by Src-non-receptor kinase. (thermofisher.com)
Phosphorylation of EGFR at Y1086 specifically allows binding of the adaptor protein GRB2, leading to activation of the MAPK pathway. (thermofisher.com)
Assessment of tyrosine phosphorylation of two sperm proteins (p105/81) showed greatly increased levels of phosphotyrosine in response to capacitation but a negligible increase in response to progesterone stimulation. (dundee.ac.uk)
Pretreatment with genistein (50 and 250 micromol/l) decreased capacitation-induced tyrosine phosphorylation and resulted in a loss of phosphorylation in response to progesterone treatment. (dundee.ac.uk)
d Quantification of ERK phosphorylation in organoids, 24 h after induction of control, BRAF or KRAS transgenes, using a capillary protein analysis. (researchgate.net)
Fig. 1: Serum mitogen-induced phosphorylation of PI3KC2-β induces complex formation with 14-3-3 proteins. (nature.com)
Fig. 5: mTORC2 signalling triggers PKN2 activation to control PI3KC2-β phosphorylation and sequestration with 14-3-3 proteins. (nature.com)
This process leads to the activation of each receptors' tyrosine kinase and the subsequent phosphorylation of tyrosine residues located on their C-terminal tails. (plos.org)
Addition of antibody to cancer cells resulted in phosphorylation and subsequent degradation of the EphB4 protein, suggesting a mechanism that is ligand mimetic and tumour suppressive. (oncotarget.com)
Binding of Sema4D to plexin-B1 stimulates the intrinsic tyrosine kinase activity of ErbB-2, resulting in the phosphorylation of both plexin-B1 and ErbB-2. (rupress.org)
Our data indicate that ErbB-2 is an important component of the plexin-B receptor system and that ErbB-2-mediated phosphorylation of plexin-B1 is critically involved in Sema4D-induced RhoA activation, which underlies cellular phenomena downstream of plexin-B1, including axonal growth cone collapse. (rupress.org)
MuSK, Downstream of Kinase 7 (DOK7), and βAChR were immunoprecipitated and their phosphorylation levels identified by immunoblotting. (ox.ac.uk)
Poultry dust extract activated STAT-3 phosphorylation in Beas2B and normal human bronchial epithelial cells and in mouse lungs. (cdc.gov)
Because ErbB3 contains a defective kinase domain, the kinase domain of ErbB2 is responsible for initiating the tyrosine phosphorylation signal through the heterodimeric receptor. (bio-techne.com)
ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). (univ-amu.fr)
Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, reorganization of the actin cytoskeleton and activation of PTK2/FAK1. (drugbank.com)
By a broad mass spectrometry based approach on whole cells we are in the process of identifying additional such proteins and their phosphorylation status. (lu.se)

Detects human ErbB2/Her2 in direct ELISAs. (rndsystems.com)
Detection of ErbB2/Her2 in MCF-7 human cell line by Flow Cytometry. (rndsystems.com)
MCF-7 human cell line was stained with Human Anti-Human ErbB2/Her2 (Research Grade Trastuzumab Biosimilar) Alexa Fluor® 700-conjugated Monoclonal Antibody (Catalog # FAB9589N, filled histogram) or irrelevant antibody (open histogram). (rndsystems.com)
Recombinant human ErB2 / Her2 (1129-ER) blocks anti-ErbB2 mediated inhibition of SK-BR-3 human breast cancer proliferation. (novusbio.com)
Measured by its ability to block anti-ErbB2 mediated inhibition of SK‑BR‑3 human breast cancer cell proliferation. (novusbio.com)
875. The ED 50 for this effect is 0.3-1.2 μg/mL in the presence of 0.6 µg/mL Anti-Human ErbB2/Her2 Monoclonal Antibody (Trastuzumab, Catalog # MAB9589 ). (novusbio.com)
EGFR belongs to the HER/ERbB family of proteins that includes three other receptor tyrosine kinases, ERbB2, ERbB3, ERbB4. (thermofisher.com)
The ErbB/HER family of receptor tyrosine kinases (RTKs) consists of four family members: the epidermal growth factor receptor (EGFR/ErbB1), HER2 (ErbB2/Neu), HER3 (ErbB3), and HER4 (ErbB4). (plos.org)
ERBB2 is a protein that is also known as HER2 (human epidermal growth factor receptor 2). (antibodyguide.com)
ErbB2, also called Neu and Her2, is a transmembrane glycoprotein in the ErbB family of tyrosine kinase receptors for EGF superfamily growth factors. (bio-techne.com)
Typically, heterodimerization with ErbB2 forms the high affinity receptor complex. (bio-techne.com)

The protein encoded by this gene is a member of the ALK/LTK receptor family of receptor tyrosine kinases (RTKs) whose ligand is unknown. (wikipedia.org)
A common heterophilic ligand for these RTK family members is definitely Gas6 a vitamin K-dependent protein that is widely secreted by most cells including the lungs intestine Serping1 and vascular endothelium (43). (exposed-skin-care.net)
The only ligand recognized to bind MST1R (RON) is Macrophage Stimulating 1 (MST1), also known as Macrophage Stimulating Protein (MSP) or Hepatocyte Growth Factor-Like Protein (HGFL). (frontiersin.org)
Activation of kinase activity occurs after ligand recognition and binding. (rndsystems.com)
Peptide exclusion was used to identify the epitope targeted by this antibody within the cysteine-rich region of the EphB4 protein, a sequence defined as a potential ligand interacting interface. (oncotarget.com)
Despite significant promiscuity between other Eph family members and the ephrin ligands, the single physiologically-relevant ligand of the EphB4 receptor is ephrin-B2 [ 2 ]. (oncotarget.com)
Both the receptor and the ligand are membrane-bound but usually expressed on neighbouring cells. (oncotarget.com)

Closely related to the insulin receptor family of RTKs. (wikipedia.org)
Receptor tyrosine kinases (RTKs) play fundamental tasks in varied cell functions including proliferation differentiation survival migration and rate of metabolism (16). (exposed-skin-care.net)
Nuclear localized HER family receptor tyrosine kinases (RTKs) have been observed in primary tumor specimens and cancer cell lines for nearly two decades. (plos.org)
This family of RTKs has been highly implicated in the formation and progression of various cancers via aberrant overexpression, kinase activation, and mutation [1] , [2] . (plos.org)
While the classical membrane-bound functions of HER family RTKs have been extensively studied, accumulating data suggest that these receptors can be found in the cell's nucleus where they can function as co-transcriptional activators [4] , [5] . (plos.org)
The ROR2 protein is part of a family of proteins known as receptor tyrosine kinases (RTKs), which play a role in chemical signaling within cells. (medlineplus.gov)

Phosphorylated tyrosine residues recruit various intracellular adaptor and effector molecules that result in the propagation of growth promoting signal transduction cascades [1] , [2] . (plos.org)
Involved in Ras protein signal transduction and transmembrane receptor protein tyrosine kinase signaling pathway. (zfin.org)

Receptor tyrosine-protein kinase erbB-2, also known as HER2/Neu (human epidermal growth factor receptor 2), is a member of the human epidermal growth factor receptor family. (meridianbioscience.com)
As ErbB-family ligands and receptors are highly expressed within the stem-cell niche 7 , we hypothesize that strong endogenous regulators must control the pathway in the stem-cell compartment. (nature.com)
The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases. (nature.com)
Here, we show that plexin-B family members stably associate with the receptor tyrosine kinase ErbB-2. (rupress.org)
ErbB4, also called Her4 (human epidermal growth factor receptor 4), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. (bio-techne.com)
ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors. (bio-techne.com)

We demonstrate that protein kinase N (PKN) facilitates mTORC1 signalling by repressing PI3KC2-β-mediated phosphatidylinositol-3,4-bisphosphate synthesis downstream of mTORC2. (nature.com)

The HER2 receptor does not bind to any known ligands, however, its dimerization arm is innately positioned in an open conformation. (plos.org)

The cytoplasmic region contains a juxtamembrane motif with two tyrosine residues which are the major autophosphorylation sites, a kinase domain, and a conserved sterile alpha motif (SAM) in the carboxy tail which contains one conserved tyrosine residue. (rndsystems.com)
EGFR is a transmembrane receptor and binding of its cognate ligands such as EGF (Epidermal Growth Factor) and TGF alpha (Transforming Growth Factor alpha) to the extracellular domain leads to EGFR dimerization followed by autophosphorylation of the tyrosine residues in the cytoplasmic domain. (thermofisher.com)

Receptor that binds specifically to PDGFB and PDGFD and has a tyrosine-protein kinase activity. (abcam.com)
This gene encodes a protein that binds ephrin-A ligands. (creativebiomart.net)

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. (origene.com)
Scientific Background TrkA is a member of the neurotrophic tyrosine kinase receptor family. (biosensis.com)

Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein and member of the protein kinase superfamily that regulates cell growth and differentiation. (biolegend.com)
EGFR (Epidermal growth factor receptor, HER1, ErbB1) is encoded by the EGFR gene located on chromosome 7 in humans. (thermofisher.com)
Upon receptor activation and signaling, EGFR is endocytosed and targeted for degradation or recycling. (thermofisher.com)
Mutations in the EGFR gene are associated with lung cancer and multiple alternatively spliced transcript variants encode different protein isoforms of EGFR have been found. (thermofisher.com)
It is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. (antibodyguide.com)
Chemical inhibition and siRNA knockdown experiments demonstrated that STAT-3 activation is dependent on the activation of nonreceptor tyrosine-protein kinase 2 (TYK2) and epidermal growth factor receptor (EGFR) tyrosine kinases. (cdc.gov)
Our studies show that poultry dust extract controls the induction of immune and inflammatory mediator expression via a cellular pathway involving oxidative stress-mediated STAT-3 activation by TYK2 and EGFR tyrosine kinases. (cdc.gov)

MA5-14485 targets Epidermal Growth Factor Receptor in IHC (P) applications and shows reactivity with Human samples. (thermofisher.com)
Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis. (nature.com)

and transmembrane receptor protein tyrosine kinase signaling pathway. (nih.gov)
This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. (origene.com)
Recombinant Human C-C chemokine receptor type 8(CCR8) referenced in "The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis", Immunity , 2021. (cusabio.com)
Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. (drugbank.com)
In human breast epithelial cells Wnt-5a activates the canonical b-catenin pathway as well as the non-canonical Ca2+/calmodulin and planar cell polarity (PCP) pathways. (lu.se)

Belongs to the protein kinase superfamily. (lu.se)

BACKGROUND AND OBJECTIVES: Up to 50% of patients with myasthenia gravis (MG) without acetylcholine receptor antibodies (AChR-Abs) have antibodies to muscle-specific kinase (MuSK). (ox.ac.uk)

Here we show that 70% of AChR-Ab-seronegative MG patients, but not AChR-Ab-seropositive MG patients, have serum auto-antibodies against the muscle-specific receptor tyrosine kinase, MuSK. (nih.gov)

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. (creativebiomart.net)
Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. (creativebiomart.net)
The EPH subfamily is the biggest group of receptor protein kinases and they take part in vital nervous system function and development. (prospecbio.com)

Soluble Axl (sAxl) is present in cell-conditioned medium of CUDC-305 (DEBIO-0932 ) tumor cells growing in vivo and in vitro and in the sera of humans mice and rats (23 50 However the identities of the sAxl-generating protease(s) and the mechanism(s) that account for this process remain unknown. (exposed-skin-care.net)
Vascular endothelial growth factor receptor-2 (VEGFR2) is a member of the VEGF family of receptor tyrosine kinase proteins, which are expressed on both endothelial and tumor cells, are one of the key proteins contributing to cancer development, and are involved in drug resistance. (researchgate.net)
Membrane-bound HER receptors activate numerous tumor promoting signaling cascades via this mechanism, including the PI3K/AKT, Ras/Raf/Mek/Erk, PLCγ/PKC, and signal transducer and activator of transcription (STAT) pathways [1] , [2] . (plos.org)
Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium. (nature.com)
Here, we demonstrate the application of base editors for the generation of complex tumor models in human ASC-derived organoids. (bvsalud.org)

Classically, HER family members function from the cell surface, where binding to cognate ligands can induce receptor homo- or hetero-dimerization with other HER family receptors [3] . (plos.org)

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. (bio-techne.com)

EphB4 is a membrane-bound receptor tyrosine kinase (RTK) commonly over-produced by many epithelial cancers but with low to no expression in most normal adult tissues. (oncotarget.com)

Gene control of tyrosine kinase TIE2 and vascular manifestations of infections. (cdc.gov)

receptor tyrosine kinase exists like a transmembrane protein and as a soluble molecule. (exposed-skin-care.net)
Several studies shown that Axl could mediate cell adhesion and aggregation through homotypic ectodomain associations (9 23 Both CUDC-305 (DEBIO-0932 ) murine and human being Axl proteins undergo proteolytic processing to yield a soluble form of this molecule. (exposed-skin-care.net)
Murine Axl is definitely cleaved extracellularly to generate a soluble ectodomain of approximately 65 kDa (23) whereas cleavage of human being Axl is definitely mapped to the 14-amino-acid (aa) stretch in the extracellular region and corresponds to the soluble CUDC-305 (DEBIO-0932 ) form with a higher molecular mass of 80 kDa (50). (exposed-skin-care.net)
Soluble monomeric ligands bind the receptor but do not induce receptor autophosphorylation and activation (2). (rndsystems.com)
En outre, il y avait une aug- mentation significative de la forme soluble du c-kit dans le sérum des patients atteints de pemphigus vulgaire actif par rapport aux témoins. (who.int)

Explore the normal functions of human genes and the health implications of genetic changes. (medlineplus.gov)
Wnts are a family of genes that have been implicated in many human tumours, so far mainly studied in colorectal cancer where activated Wnt signalling occurs in a vast majority of tumours. (lu.se)

COLO 205 human colorectal adenocarcinoma cell line was stained with Rat Anti-Human/Mouse EphB2 APC-conjugated Monoclonal Antibody (Catalog # FAB467A, filled histogram) or isotype control antibody (Catalog # IC006A , open histogram). (rndsystems.com)

Oncogenic mutations in KRAS or BRAF are frequent in colorectal cancer and activate the ERK kinase. (researchgate.net)
For many transcription factors, including multiple members of FOX, HOX, and NR families, we show that human cancers accumulate fewer mutations than expected by chance that increase or decrease affinity of predicted binding sites. (biomedcentral.com)
Frequencies of synonymous and non-synonymous substitutions allow studying selection of cancer somatic mutations in protein-coding regions [ 11 ]. (biomedcentral.com)
Some of these mutations change single protein building blocks (amino acids) in the ROR2 protein, while others lead to the production of an abnormally short, nonfunctional version of the protein. (medlineplus.gov)
Because these genetic changes prevent any functional ROR2 protein from being made, they are described as "loss-of-function" mutations. (medlineplus.gov)
Unlike the mutations that cause Robinow syndrome (described above), the ROR2 gene mutations that cause brachydactyly type B1 are described as "gain-of-function" because they appear to cause the ROR2 protein to be continuously active. (medlineplus.gov)
Gene mutations that cause loss of receptor function are associated with CONGENITAL INSENSITIVITY TO PAIN WITH ANHIDROSIS, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis. (bvsalud.org)
Deregulation of these receptors by mutations has been implicated in various human malignancies, including akut myeloid leukemia and melanoma. (lu.se)

Staining was performed using our Staining Membrane-associated Proteins protocol. (rndsystems.com)
View our protocol for Staining Membrane-associated Proteins . (rndsystems.com)

There are two classes of receptors, designated A and B. Both the A and B class receptors have an extracellular region consisting of a globular domain, a cysteine-rich domain, and two fibronectin type III domains. (rndsystems.com)

In vivo , the ligands and receptors display reciprocal expression (3). (rndsystems.com)

Recombinant Human Novel Coronavirus Spike glycoprotein(S), partial (Active) referenced in "Insights into neutralizing antibody responses in individuals exposed to SARS-CoV-2 in Chile", Science Advances , 2021. (cusabio.com)
Recombinant Human Novel Coronavirus Spike glycoprotein(S) (D614G), partial (Active) referenced in "Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries", Cell discovery , 2021. (cusabio.com)

The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. (creativebiomart.net)
This Mouse Ephrin Type-A Receptor 4 (EphA4) ELISA Kit from Innovative Research is intended for quantitative detection of mouse EphA4 in cell culture supernates, serum and plasma (heparin, EDTA). (innov-research.com)
Expression system for standard: EPH receptor A4 (ephrin type-A receptor 4) is a protein that in humans is encoded by the EPHA4 gene. (innov-research.com)

Bound protein had been eluted with 4X lithium dodecyl sulfate (LDS) launching buffer solved by SDS- Web page and immunoblotted with a particular antibody. (bioxorio.com)
Bound proteins were eluted with 4X LDS loading buffer resolved by SDS-PAGE and immunoblotted with a specific antibody. (bioxorio.com)
RVX-208 P2 pellets were solubilized in the homogenization buffer containing 1% sodium deoxycholate for 1 h at 4°C. Solubilized proteins (150 μg) were incubated with a rabbit antibody against CaMKIIα or mGluR1a. (bioxorio.com)
Proteins were separated on Novex 4-12% gels and probed with a mouse antibody against CaMKIIα or mGluR1a. (bioxorio.com)

The receptor tyrosine kinases KIT and FLT3 are both important regulators of development and maintenance of a number of different cell types. (lu.se)

Dephosphorylation with calf-intestinal alkaline phosphatase (CIP) For dephosphorylation of phosphorylated GST-fusion proteins proteins were incubated with active CaMKIIα (100 ng) in 25 μl reaction buffer containing 10 mM HEPES pH 7.4 10 mM MgCl2 1 mM Na3VO4 1 mM DTT 50 μM ATP and 2.5 μCi/tube [γ-32P]ATP (~3000 RVX-208 Ci/mmol PerkinElmer). (bioxorio.com)

The signaling pathways activated by the oncogenic mutants are to some extent unique and different from wild-type receptor signaling. (lu.se)

Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. (drugbank.com)

Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis. (cusabio.com)

Detection of EphB2 in COLO 205 Human Cell Line by Flow Cytometry. (rndsystems.com)
TotalSeq™-D antibodies are compatible with Mission Bio's Tapestri Single-Cell Sequencing Platform for simultaneous detection of DNA and Protein. (biolegend.com)
TotalSeq™-D reagents are designed to profile protein expression at single cell level. (biolegend.com)
Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. (origene.com)
Further analysis of transcription factors with conserved binding motifs can reveal cell regulatory pathways crucial for the survivability of various human cancers. (biomedcentral.com)
These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. (embl.de)
as a cell surface-associated protein, it is easily accessible to drugs and as a kinase it is amenable to targeted inhibition by small molecules. (antibodyguide.com)
HYPOTHESIS: Do LRIG Proteins Regulate Stem Cell Quiescence by Promoting BMP Signaling? (nature.com)
Jensen, K. B. & Watt, F. M. Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence. (nature.com)
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. (bio-techne.com)
Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. (univ-amu.fr)
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. (drugbank.com)
This technologic and biologic revolution continued through the 1960s to today, and the explosion in technology has fueled the current expansion of knowledge into the working of the human cell. (medscape.com)
[ 5 ] Ideally, SCID can be detected in a newborn before the onset of infections, with one well-documented example by screening of T-cell-receptor excision circles. (medscape.com)
In normal breast epithelium, Wnt-5a is important for cell-ECM adhesion and activation of the collagen receptor DDR1. (lu.se)

Overexpression and/or activation of c-Met, the protein tyrosine kinase receptor for the hepatocyte growth factor/scatter factor (HGF/SF), and the protein tyrosine kinase, Src, have been implicated in the progression and metastasis of human colorectal carcinoma (CRC). (oldcitypublishing.com)

The extracellular domains of human and mouse EphB2 share 99% amino acid identity. (rndsystems.com)
Sequence A DNA sequence encoding the signal peptide and extracellular domain of human TrkA (amino acids 1- 413) was fused to the Fc region of human IgG1 (amino acids 104-330). (biosensis.com)
Results from these analyses demonstrated that the C-terminal domain of HER3 (CTD, amino acids distal to the tyrosine kinase domain) contained potent transactivation potential. (plos.org)
EFNA1 Human Recombinant produced in HEK293 cells is a single, glycosylated polypeptide chain (a.a 19-182) containing 170 amino acids including a 6 a.a C-terminal His tag. (prospecbio.com)

In approximately 80% of patients, auto-antibodies to the muscle nicotinic acetylcholine receptor (AChR) are present. (nih.gov)
HRP-conjugated secondary antibodies and enhanced chemiluminescence were used to visualize proteins. (bioxorio.com)

There is no detectable cross-reactivity with other relevant proteins. (innov-research.com)

Anatomy20

Organisms6

Diseases3

Chemicals and Drugs161

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Phenomena and Processes45

Disciplines and Occupations1

Information Science3

Phosphorylation20

ErbB211

Ligand7

RTKs6

Signal transduction2

ERBB6

Phosphatidylinositol1

HER21

Residues2

Binds2

Neurotrophic tyrosine2

EGFR7

Epidermal growth2

Pathway5

Superfamily1

Myasthenia Gravis1

MUSK1

Subfamily3

Tumor5

Homo1

Recombinant Proteins1

Membrane-bound receptor1

Vascular1

Soluble5

Genes2

Monoclonal1

Mutations8

Staining Membrane-associated Proteins2

Class receptors1

Ligands and receptors1

Glycoprotein2

Ephrin3

Antibody4

FLT31

Phosphatase1

Type1

Isoform1

Tie21

Cell15

Overexpression1

Amino4

Antibodies2

Reactivity1