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  • ovum
  • By producing a diploid ovum (egg cell), the moms would double their own DNA, giving either a ZZ or a WW, but WW's are nonviable. (blogspot.com)
  • Q: What is the Catholic perspective on the ethics of parthenogenesis to produce stem cells from an ovum without fertilization by sperm? (lifeissues.net)
  • Dolly, the cloned ewe, was made by removing the nucleus from an oocyte, or unfertilized ovum, of one breed of sheep, and replacing it with nuclear material from an adult donor cell taken from a different breed of sheep. (patents4life.com)
  • neuronal
  • Made significant progress in Parkinson's program including the development of a new highly-efficient manufacturing method for generating neuronal cells and conducted preliminary toxicology and pharmacology studies in animals. (marketwired.com)
  • oocyte
  • 60. A differentiated cell derived from a stem cell obtained from a parthenogenetically activated oocyte from a human donor. (patentsencyclopedia.com)
  • 61. The differentiated cell of claim 60, wherein the differentiated cell is histocompatible with the oocyte donor. (patentsencyclopedia.com)
  • 90. A method of treating a subject in need thereof, comprising administering a cellular composition comprising differentiated cells, wherein the differentiated cells are derived from a stem cell obtained from a parthenogenetically activated oocyte from a human donor. (patentsencyclopedia.com)
  • In mammals -- and so humans -- parthenogenesis refers to a process in which an egg (oocyte) begins to divide without being fertilized by a male sperm. (lifeissues.net)
  • By "reproduction" I mean embryogenesis, the coming into existence of an embryo, not full-term fetal development, which, because the developmental potential of an unfertilized human oocyte is very minimal, is probably not possible. (lifeissues.net)
  • But parthenogenic activation induces the oocyte to divide, at least for a few days, in a way that appears characteristically human. (lifeissues.net)
  • Unless we have moral certainty that a dividing parthenogenetically activated human oocyte is not an embryo, we have an obligation to avoid research with human parthenotes. (lifeissues.net)
  • Parthenogenic activation means causing the oocyte to begin dividing without fertilization by human sperm. (patents4life.com)
  • Now you have cloned the female donor of the "human oocyte" of step (a), without the need to remove the nucleus of the oocyte and replace it with a donor nucleus (from a male or second female). (patents4life.com)
  • parthenogenesis
  • Since mamalian reproduction is sexual, parthenogenesis in humans is a profoundly abnormal process. (lifeissues.net)
  • Although we use the same term as we do with insects and lizards, we don't know if true reproduction ever takes place in human parthenogenesis. (lifeissues.net)
  • Footnote 49, introduced at this precise point in the text, mentions three examples, one of which is "human parthenogenesis. (lifeissues.net)
  • differentiate
  • Their previous studies with hpNSCs, said the authors, had shown that the cells could also be "chemically directed" to differentiate into multipotent neural stem cells and were able to be frozen for future use. (scienmag.com)
  • The appeal of using embryonic stem (ES) cells for regenerative medicine lies in their pluripotency and resulting ability to differentiate into all somatic cell types. (ox.ac.uk)
  • world's
  • Stem cells, their differentiated progeny, and the products produced therein, may be capable of unlocking treatments for some of the world's most devastating diseases. (patentsencyclopedia.com)
  • development
  • After studies in turkeys were publicized, it was recognized that parthenogenic development was also occurring in chickens. (blogspot.com)
  • Progressed the Cornea program by the development of endothelial-like cells for 3D corneal structures as part of our Indian collaboration. (marketwired.com)
  • We have made excellent progress in our therapeutic development programs, being able to start our non-human primate study in our Parkinson's disease program earlier than anticipated, and report top line data at the American Academy of Neurology Annual Meeting," stated Dr. Andrey Semechkin, ISCO's CEO and Co-Chairman. (marketwired.com)
  • The letter addresses recent corporate governance and operational changes, as well as providing an update on ISCO's Research and Development accomplishments, challenges and 2012 - 2013 major milestones and information on both the Lifeline Skin Care's and Lifeline Cell Technology's recent activities. (marketwired.com)
  • Parthenogenic activation is the production of embryonic cells, with or without eventual development into an adult, from a female gamete in the absence of any contribution from a male gamete. (patents4life.com)
  • California
  • With more than two million page views and more than 4,500 items, this blog provides news and commentary on public policy, business and economic issues related to the $3 billion California stem cell agency, officially known as the California Institute for Regenerative Medicine(CIRM). (blogspot.com)
  • The California stem cell agency's $230 million disease team research effort, which boosted CIRM's spending beyond $1 billion, attracted moderate news coverage this morning and late yesterday. (blogspot.com)
  • The California Stem Cell Report is going dark this week. (blogspot.com)
  • The California Stem Cell Report is the only nongovernmental website devoted solely to the $3 billion California stem cell agency. (blogspot.com)
  • telomerase
  • In addition to the deletion of one or more genes coding for essential element(s) of the telomerase holoenzyme , success will also require the deletion of some essential element of the machinery for the Alternative Lengthening of Telomeres (ALT) phenomenon , observed in a minority of cancer cells. (immortalitymedicine.tv)
  • Yeast cells have the ability to lengthen telomeres through a telomerase-independent mechanism involving telomere recombination, and there has been evidence for some time suggesting that ALT cancers lengthen telomeres through a similar process. (immortalitymedicine.tv)
  • neurological
  • In one embodiment, a patient suffering neurological manifestations of a viral infection is administered a therapeutically active dose(s) of mesenchymal stem cells at a frequency and concentration sufficient to induce amelioration, remission or cure of neurological manifestations. (patents.com)
  • and d) performing additional administrations of said stem cells based on neurological response achieved. (patents.com)
  • cardiac
  • The invention also includes isolated cardiomyocytes and cardiac progenitors differentiated by the methods as well as the use of these cells in methods of treating and preventing cardiac diseases and conditions. (patentsencyclopedia.com)