Human nasal epithelium. Medical search. Frequent questions

The effect of WS and CS on mucous cell hyperplasia in mice and in human primary airway epithelial cells (AECs) was compared with replicate the findings in human cohorts. (nih.gov)
These results suggest that DNA damage is present in nasal epithelial cells in Mexico City children. (nih.gov)
The epithelial lining of the large airways and contiguous structures, including the paranasal sinuses, middle ears, and posterior nose, consists of ciliated pseudostratified columnar epithelium. (medscape.com)
14. Tc17/IL-17A Up-Regulated the Expression of MMP-9 via NF-κB Pathway in Nasal Epithelial Cells of Patients With Chronic Rhinosinusitis. (nih.gov)
16. TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21. (nih.gov)
19. Epithelial activators of type 2 inflammation: Elevation of thymic stromal lymphopoietin, but not IL-25 or IL-33, in chronic rhinosinusitis with nasal polyps in Chicago, Illinois. (nih.gov)
20. Analysis of epidermal growth factor signaling in nasal mucosa epithelial cell proliferation involved in chronic rhinosinusitis. (nih.gov)
Ciliated epithelial samples were obtained from 76 children and adult volunteers aged 6 months to 43 years by brushing the inferior nasal turbinate. (bmj.com)
Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures. (ntu.edu.sg)
2016) Human nasal epithelial cells derived from multiple subjects exhibit differential responses to H3N2 influenza virus infection in vitro. (ntu.edu.sg)
A detailed protocol is presented here to describe an in vitro organoid model from human nasal epithelial cells. (jove.com)
Human nasal epithelial organoids, or HNE organoids, produce lumens of varying sizes that correlate with the CFTR activity, distinguishing between CF and non-CF organoids. (jove.com)
The human airway, from the nasal passage to the alveolar sacs, is covered with a continuous epithelial sheet that differs in morphology and cellular composition between the conducting and respiratory zones. (stemcell.com)
The alveolar epithelium is lined with type I and II alveolar epithelial cells (AECs). (stemcell.com)
We therefore, set up an in vitro model of human Airway Epithelial Cells of Nasal origin (hAECN) close to real human cell functionality, specifically adapted to study the biological effects of exposure to indoor gaseous pollution at the environmental level. (vitrocell.com)
In comparison to the model aminopeptidase substrate (Ala-MCA), the synthesized compounds yielded fluorescent 7-amino-4-methylcoumarin following incubation with nasal epithelial cells. (ccsenet.org)
The pseudovirions were applied to track viral entry at a single particle level in four types of the human respiratory cells: nasal epithelial cells (HNEpC), pulmonary alveolar epithelial cells (HPAEpiC), bronchial epithelial cells (BEP-2D), and oral epithelial cells (HOEC). (researchsquare.com)
The dual-labeled virus was used to infect the human airway epithelium cultures to image the entry pathway and infection efficiency at a single particle level in four different respiratory epithelial cells, including human nasal epithelial cells (HNEpC), human oral epithelial cells (HOEC), human bronchial epithelial cells (BEP-2D), and human pulmonary alveolar epithelial cells (HPAEpiC). (researchsquare.com)
The olfactory epithelium is a specialized epithelial tissue inside the nasal cavity that is involved in smell. (theinfolist.com)
In Vitro study showing that vitamin D reduced SARS-CoV-2 replication in adult nasal epithelial cells via increased type I interferon expression. (c19early.org)

A patch of tissue on the roof of the nasal cavity called the olfactory epithelium houses the large family of receptors responsible for detecting odors. (nih.gov)
Their surface is covered with a layer of mucus and cells called the olfactory epithelium. (dogster.com)
Within the nasal cavity of most mammals, there's a sheet of tissue called the olfactory epithelium that converts odor molecules into the neural signals that the brain interprets as smells. (kazu.org)

Other studies evaluating the airway epithelia, such as primary ciliary dyskinesia, may also find these methods helpful. (jove.com)
We have assessed the effect of a number of antibiotics on the ion transport processes of airway epithelia. (nih.gov)

1. uPA affects the CRSsNP nasal mucosa epithelium apoptosis by regulating WIF1. (nih.gov)
3. Involvement of B2 receptor in bradykinin-induced proliferation and proinflammatory effects in human nasal mucosa-derived fibroblasts isolated from chronic rhinosinusitis patients. (nih.gov)
6. Expression of long pentraxin 3 in human nasal mucosa fibroblasts, tissues, and secretions of chronic rhinosinusitis without nasal polyps. (nih.gov)
11. Thromboxane A2 Regulates CXCL1 and CXCL8 Chemokine Expression in the Nasal Mucosa-Derived Fibroblasts of Chronic Rhinosinusitis Patients. (nih.gov)
As the olfactory mucosa is hidden deep within the nasal cavity, tissue sample procurement is not a practical option in patients while they are suffering from COVID-19. (mpg.de)
To understand the precise contribution and molecular nature of multimeric secretory IgAs induced by intranasal vaccines, we developed 99 monoclonal IgAs from nasal mucosa and 114 monoclonal IgAs or IgGs from nonmucosal tissues of mice that were intranasally immunized with the SARS-CoV-2 spike protein. (elifesciences.org)
The nonmucosal IgAs exhibited shared origins and both common and unique somatic mutations with the related nasal IgA clones, indicating that the antigen-specific plasma cells in the nonmucosal tissues originated from B cells stimulated at the nasal mucosa. (elifesciences.org)
The olfactory nerve is sensory in nature and originates on the olfactory mucosa in the upper part of the nasal cavity. (theinfolist.com)

The goals of Dr. Hagan's research team are to monitor eosinophils in respiratory secretions and blood as well as steroid or steroid metabolites, which together may help document adherence, identify steroid resistance, and allow for individualized treatment in specific patients who have conditions such as eosinophilic asthma and chronic rhinosinusitis with nasal polyps. (mayo.edu)

4. Effects of simulated bleeding in an in vitro nasal fibroblast wound healing model. (nih.gov)
Initial evaluation performed on sheep tracheal epithelium in vitro demonstrated that trimethoprim and tetracycline induced a rapid decrease in electrogenic ion transport. (nih.gov)

9. Differential expression of Toll-like receptor pathway genes in chronic rhinosinusitis with or without nasal polyps. (nih.gov)
12. A Retrospective Analysis of γδ T Cell Expression in Chronic Rhinosinusitis and Its Association with Recurrence of Nasal Polyps. (nih.gov)
13. GSK-3β activation index is a potential indicator for recurrent inflammation of chronic rhinosinusitis without nasal polyps. (nih.gov)
15. Increased expression of IL-19 in the epithelium of patients with chronic rhinosinusitis and nasal polyps. (nih.gov)

Scientists once thought that the olfactory epithelium was responsible for detecting odors while the vomeronasal organ was responsible for detecting pheromones, and the two structures were considered completely separate," Dr. Barry Davis, director of NIDCD's taste and smell program, says "But this research identifies a new class of receptors in the olfactory epithelium that are able to detect pheromones. (nih.gov)
The olfactory epithelium is the part of the olfactory system directly responsible for detecting odors. (theinfolist.com)

The nasal tissues appear to be the most sensitive target of inhalation exposure, with onset of noticeable irritation occurring in seconds (0.3 ppm). (cdc.gov)
They then exposed the animals' nasal tissues to a range of different scent combinations. (cosmosmagazine.com)
But they are capable of multiplying and producing various cells of a particular lineage that serve as the workforce for specialized tissues, such as the olfactory epithelium. (nih.gov)

By lectin histochemistry we discovered moderate to abundant appearance from the human-like trojan receptors in every explant systems but minimal binding from the lectins that recognize avian-like receptors, in the nasal especially, tracheal and bronchial epithelium. (woofahs.com)

Making a confident diagnosis of primary ciliary dyskinesia can at times be very difficult as abnormalities of the epithelium and cilia may also be found purely as a result of acquired ciliary defects. (bmj.com)

Nasal biopsies from the posterior inferior turbinate were examined in children in grades one through five, including 12 controls from a low-polluted coastal town and 87 Mexico City children. (nih.gov)
Biopsies of the nasal epithelium taken 7 days after dosing were normal. (ox.ac.uk)
We performed systematic analysis of tRNA abunandance across in various models used in cystic fibrosis (CF) research and drug development, including Fischer rat thyroid (FRT) cells, patient-derived primary human bronchial epithelia (HBE) from lung biopsies, primary human nasal epithelia (HNE) from nasal curettage, intestinal organoids, and airway progenitor-directed differentiation of human induced pluripotent stem cells (iPSCs). (biomedcentral.com)

S-IgA plays an important role in the protection and homeostatic regulation of the airway, intestinal and vaginal epithelium through a process known as immune exclusion and immunosuppression ( Matsumoto, 2022 ). (elifesciences.org)
This ejaculation contains as many as 400 million sperms but only about 100 sperms reach the fallopian tube because many sperms are either killed by the acidity of female genital tract or engulfed by the phagocytes of the vaginal epithelium. (studyinnovations.com)

Hansen A, Witt M, Hummel T. Unconventional neurons in the nasal cavity of humans. (wikipedia.org)
Olfactory receptor neurons are continuously replaced by mitotic division of the basal cells of the olfactory epithelium. (wikibooks.org)
Scientists at the Max Planck Research Unit for Neurogenetics in Frankfurt in collaboration with physicians and scientists at the University Hospitals Leuven (Leuven, Belgium) and a major hospital in Bruges, Belgium, together with scientists at NanoString Technologies Inc. in Seattle, USA, report that SARS-CoV-2 does not appear to infect the sensory neurons of the olfactory epithelium in COVID-19 patients. (mpg.de)
Earlier studies had shown that ACE2 is expressed by sustentacular cells in the human olfactory epithelium but not by olfactory sensory neurons, the nerve cells that are stimulated by odorants in the inhaled air and that transmit electrical signals to the olfactory bulb. (mpg.de)
In addition, canines have hundreds of millions more of the specialized odor-detecting neurons than humans. (kazu.org)
GnRH-secreting neurons in vertebrates originate outside the brain, in the nasal placode [ 10 ], during embryonic life, and migrate into the brain along the olfactory/vomeronasal and terminal nerves to their principal target region, the preoptic area of the hypothalamus [ 11,12 ] (fig. 1 a). (karger.com)
Structure Olfactory epithelium consists of four distinct cell types: * Olfactory sensory neurons * Supporting cells * Basal cells * Brush cells Olfactory sensory neurons The olfactory receptor neurons are sensory neurons of the olfactory epithelium. (theinfolist.com)

The height of this epithelium decreases in more distal regions of the conducting zone and resembles a cuboidal epithelium in the small airway. (stemcell.com)

In vertebrates the main olfactory system detects odorants that are inhaled through the nose where they come to contact with the olfactory epithelium, which contains the olfactory receptors. (wikibooks.org)
It doesn't take an anatomist to see there are obvious external differences between the human nose and that of the dog and cat. (dogster.com)
The internal nose is divided into two nasal cavities that run the length of the muzzle in dogs and cats. (dogster.com)
In humans, the nose has about 400 types of scent receptors, and they can detect at least 1 trillion different odors [1]. (nih.gov)
The dog's nose is kept moist by lacrimal (tear) and nasal gland secretions. (petmassage.com)
They are protected by the pink nasal epithelium or the special covering of the internal nose. (floofmania.com)
The typical symptoms of a cold include cough , runny nose , sneezing , nasal congestion , and a sore throat , sometimes accompanied by muscle ache , fatigue , headache , and loss of appetite . (wikipedia.org)

Following the nasal stimulation with LTD4, the concentration of dye in the nasal lavage fluid rapidly increased. (researchgate.net)
In OA-sensitized guinea pigs, the excretions of dye into nasal lavage fluid were recognized soon after the topical antigenic stimulation and continued for over 60 minutes. (researchgate.net)
Currently, the evaluation of intranasal vaccine efficacy is based on the measurement of polyclonal antibody titers in nasal lavage fluid. (elifesciences.org)

The critical effects of acute duration iodomethane exposure are: (1) fetal losses in rabbits, (2) lesions in rat nasal epithelium, and (3) transient neurotoxicity in rats. (cdc.gov)

The nasal cavities house the turbinate bones and paranasal sinuses. (petmassage.com)

Dogs have an additional olfactory cavity called the vomeronasal organ which is also lined with olfactory epithelium. (petmassage.com)

Hansen A. Unconventional sensory cells in the nasal epithelia of rodents and humans. (wikipedia.org)
Sbarbati A., Merigo F, Benati D, Tizzano M, Bernardi P, Crescimanno C, Osculati F. Identification and characterization of a specific sensory epithelium in the rat larynx. (wikipedia.org)
Similar to other sensory modalities, olfactory information must be transmitted from peripheral olfactory structures, like the olfactory epithelium, to more central structures, meaning the olfactory bulb and cortex. (wikibooks.org)
In recent years, researchers have highlighted the presence of sensory receptors in unexpected areas of the human body. (msensory.com)

MPS is studying the neuropathogenesis of emerging respiratory viruses in human cerebral organoids and animal models. (nih.gov)

Funded by NIH's National Institute on Deafness and Other Communication Disorders (NIDCD) and the Howard Hughes Medical Institute, they searched the mouse's olfactory epithelium for receptors that don't respond to odors. (nih.gov)
Humans can distinguish between about 10.000 odors. (wikibooks.org)

However, olfactory dose per unit surface area is estimated to be higher in humans in the 1-7 nm size range due to the larger inhalation rate in humans. (cdc.gov)
Histological changes in respiratory and gastrointestinal epithelium have been observed from both inhalation and oral exposures, respectively. (cdc.gov)
Human exposure may occur via inhalation due to the high vapor pressure of iodomethane. (cdc.gov)
A quantitative human health risk assessment was conducted for inhalation exposure. (cdc.gov)

Solitary chemoreceptor cell proliferation in adult nasal epithelium. (wikipedia.org)
The ED50 as determined by a cell proliferation assay using human IL-20Rα and human IL-20Rβ co-transfected murine BaF3 pro-B cells is less than 1.5 ng/ml, corresponding to a specific activity of >6.7x10 5 IU/mg. (cusabio.cn)

For example, the dog's ability to detect acetic acid, a component of human skin secretions, is 100,000,000 times that of humans when tested in laboratory trials. (dogster.com)

This is a proof of the evolution change in the necessity of humans in using the olfaction. (wikibooks.org)
The olfactory epithelium (OE) is the peripheral organ for olfaction and is subject to acquired damage, suggesting a likely site of pathology in aging. (nih.gov)

0.05) and the same direction of effect in nasal brushes. (biomedcentral.com)

Derived from the embryonic nasal placode, the olfactory nerve is somewhat unusual among cranial nerves because it is capable of some regeneration if damaged. (theinfolist.com)

The degrees of overall improvement, usefulness, improvement of nasal symptoms (sneezing, nasal discharge, nasal blockage) and improvement of rhinoscopical findings (mucosal swelling and nasal secretion) were found to be dose-dependent. (researchgate.net)
The color of the mucus or nasal secretion may vary from clear to yellow to green and does not indicate the class of agent causing the infection. (wikipedia.org)

In subjects with cystic fibrosis, who exhibit increased Na+ absorption across respiratory epithelia, the responses to trimethoprim and tetracycline were enhanced, providing further evidence that these drugs inhibit Na+ absorption. (nih.gov)
A placebo-controlled study of liposome-mediated gene transfer to the nasal epithelium of patients with cystic fibrosis. (ox.ac.uk)

Solitary chemosensory cells (SCCs) (also called solitary chemoreceptor cells) are isolated elements located in epithelia of the apparatuses of endodermic origin (such as respiratory and digestive apparatuses). (wikipedia.org)
Diffuse chemosensory system Chemosensory clusters Sbarbati A, Crescimanno C, Benati D, Osculati F. Solitary chemosensory cells in the developing chemoreceptorial epithelium of the vallate papilla. (wikipedia.org)
Sbarbati A, Crescimanno C, Bernardi P, Osculati F. Alpha-gustducin immunoreactive solitary chemosensory cells in the developing chemoreceptorial epithelium of the rat vallate papilla. (wikipedia.org)
Solitary chemoreceptor cells in the nasal cavity serve as sentinels of respiration. (wikipedia.org)
Olfactory sensitivity is directly proportional to the area in the nasal cavity near the septum reserved to the olfactory mucous membrane, which is the region where the olfactory receptor cells are located. (wikibooks.org)
In humans there are about 10 million olfactory cells, each of which have 350 different receptor types composing the olfactory mucous membrane. (wikibooks.org)
Instead, the sustentacular cells, also known as supporting cells, are the main target cell type for the virus in the olfactory epithelium. (mpg.de)
There is no literature about the functions of sustentacular cells in the olfactory epithelium of humans. (mpg.de)
Both cell types are continuously regenerated from stem cells within the olfactory epithelium throughout the life of an individual. (mpg.de)
The major cell types of the large airway epithelium are goblet cells that produce and secrete mucus, ciliated cells that promote mucus motility through coordinated movement of their apical cilia, and basal cells that line the basement membrane and do not contact the apical surface of the epithelium. (stemcell.com)
In the bronchioles, the cuboidal epithelium contains secretory club cells and fewer ciliated cells than in more proximal airway regions. (stemcell.com)
Yang and Ornitz also discovered that the FEP cells crank out a molecule, called FGF20, that controls the growth of the bony parts in the nasal cavity. (nih.gov)
These studies suggested that air pollutants increase inflammation and reduce the number and activity of immune cells in the nasal epithelium, which is the body's first line of defense against respiratory infection. (nih.gov)
In cells from nasal brushings. (ox.ac.uk)
Compared to dogs, humans have far less scent cells, only 5 million. (petmassage.com)
In addition, dogs have fifteen times more cilia, hair like structures that capture scent, on their cells than humans. (petmassage.com)
Thus cells of human origin showed similar hypersensitivity to formaldehyde. (europa.eu)
Earlier results indicating increased sensitivity to formaldehyde in FANCB-deficient cells were validated by testing a human FA gene-deficient cell line (human B cell line NALM-6). (europa.eu)
In conjunction with Hirohito Kita, M.D. , of the Division of Allergic Diseases, Dr. Hagan is working to improve the understanding of allergen-induced interleukin-33 release by the airway epithelium, characterizing alternaria and ribonucleases in T-helper type 2 immunity, and identifying type 2 innate lymphoid cells in asthma. (mayo.edu)

Researchers have discovered a family of receptors that can detect such signals in mice and are found in humans, too. (nih.gov)
Dr. Buck and her colleague Dr. Stephen D. Liberles, both at the Fred Hutchinson Cancer Research Center, thus set out to hunt for pheromone receptors in the olfactory epithelium. (nih.gov)
It is also interesting to note that the human genome has about 600 - 700 genes (~2% of the complete genome) specialized in characterizing the olfactory receptors, but only 350 are still used to build the olfactory system . (wikibooks.org)
Each such cell has one of a wide range of different sensors, or receptors - up to 400 in humans. (cosmosmagazine.com)
Again, the German Shepherd has 220 million olfactory receptors, the Dachshund 125 million, the cat 60 million, and the human only six million. (dogster.com)
Human (Sia2-6Gal) and avian computer virus receptors (Sia2-3Gal) were recognized with Sambucus Nigra and Maackia amurensis lectins respectively. (woofahs.com)
Our outcomes indicate that, predicated on the appearance of Sia receptors by itself, the pig is certainly unlikely to be always a more appropriate 101975-10-4 supplier blending vessel for influenza infections than human beings. (woofahs.com)
Because sialic acids (Sia) with 2,6 and 2,3 linkages to galactose (receptors favored by human and avian influenza viruses respectively) were recognized in the porcine trachea, pigs have been implicated as intermediate hosts or as mixing vessels for reassortment [14-16]. (woofahs.com)

This double blind, parallel study compared flunisolide 2 X 25 mcg in each nostril twice daily, with placebo in the prophylaxis of nasal polyposis recurrence after surgery. (researchgate.net)
In this study, flunisolide was significantly more effective than placebo in preventing recurrence of nasal polyposis during one year's treatment after polypectomy. (researchgate.net)

With support from NIEHS, Jaspers has made many important discoveries about how air pollution affects lung immune response and what that means for human health. (nih.gov)

The nasal cavity is divided into two chambers by the bony, cartilaginous nasal septum. (petmassage.com)

The two structures used for inhaling air and scents are the nostrils and the bony nasal cavity. (petmassage.com)
In humans, it measures 9 cm2 and lies on the roof of the nasal cavity about 7 cm above and behind the nostrils. (theinfolist.com)

Functional expression of CFTR assessed by in vivo nasal potential difference measurements showed transient correction of the CF chloride transport abnormality in two patients (15 days after dosing in one patient). (ox.ac.uk)

DNA strand breaks in human nasal respiratory epithelium are induced upon exposure to urban pollution. (nih.gov)
8-hydroxy-2'-deoxyguanosine, a major mutagenic oxidative DNA lesion, and DNA strand breaks in nasal respiratory epithelium of children exposed to urban pollution. (nih.gov)

This route of exposure may be the mechanism behind the correlation between air pollution and human neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. (cdc.gov)
The documents provide guidelines for setting exposure limits consistent with the protection of human health and the environment. (inchem.org)
A physiologically based pharmacokinetic (PBPK) model for iodomethane was developed to characterize poten- tial human health effects from iodomethane exposure. (cdc.gov)
Nasal olfactory degeneration is the primary endpoint for risk assessment of acute exposure to iodomethane. (cdc.gov)
Iodomethane is a new agricultural of approximately 24 hours due to the emission patterns of active ingredient, and there are no human exposure incident the compound and air dispersion patterns ( EPA OPP Health reports related to agricultural uses. (cdc.gov)
For example, in both cell and human studies, Jaspers found that exposure to diesel exhaust increased susceptibility to influenza infection. (nih.gov)

The human respiratory system functions to transfer oxygen from the air to the circulatory system and carbon dioxide from the body to the surrounding air. (stemcell.com)

It may attract odor molecules and keep them in the vicinity of the nasal openings. (dogster.com)
The olfactory epithelium detects odorant molecules in the air, providing a sense of smell. (nih.gov)

Recent efforts include obtaining nasal and sinus material for tissue culture and evaluating disease exacerbations to advance collaborative investigations of chronic rhinosinusitis, as well as defining mechanisms of eosinophilic inflammation in human diseases. (mayo.edu)

Located in the bottom of the dog's nasal passage, Jacobson's organ detects pheromones. (petmassage.com)

Comparing the spike protein binding reactivity, angiotensin-converting enzyme-2-blocking and SARS-CoV-2 virus neutralization of monomeric and multimeric IgA pairs recognizing different epitopes showed that even nonneutralizing monomeric IgA, which represents 70% of the nasal IgA repertoire, can protect against SARS-CoV-2 infection when expressed as multimeric secretory IgAs. (elifesciences.org)
Our investigation is the first to demonstrate the function of nasal IgAs at the monoclonal level, showing that nasal immunization can provide effective immunity against SARS-CoV-2 by inducing multimeric secretory IgAs at the target site of virus infection. (elifesciences.org)

Anatomy of the Human Body. (bartleby.com)

Olfactory deposition of inhaled nanoparticles in humans. (cdc.gov)
The deposition of 1-100 nm particles in the whole nasal cavity and its olfactory region were estimated via computational fluid dynamics (CFD) simulations. (cdc.gov)

The larger the nasal cavity, the more complex the network of bony scrolls, which allows for a greater area of olfactory epithelium. (dogster.com)
The olfactory epithelium drapes over the interior walls of the nasal cavity and its curvy bony parts (red). (nih.gov)
Within the nasal cavity, is a series of scroll-shaped bony plates called turbinates. (petmassage.com)

The vomeronasal organ isn't thought to be functional in humans, but research has shown that, in mice, at least, the responses to some pheromones involve the olfactory epithelium. (nih.gov)

We have undertaken a double-blinded, placebo-controlled, clinical study of the transfer of the CFTR cDNA to the nasal epithelium of 12 CF patients. (ox.ac.uk)
Cationic liposomes complexed with plasmid containing the human CFTR cDNA were administered to eight patients, whilst four patients received placebo. (ox.ac.uk)

The efficacy, safety and optimal dose of TL-102, a powder mixture of beclomethasone dipropionate (BDP) and hydroxypropylcellulose (HCP) were studied in 250 patients with perennial nasal allergy in an intergroup comparative double-blind manner. (researchgate.net)
Other collaborative efforts have involved the following: food allergy, radiologic and endoscopy changes associated with chronic rhinosinusitis, recombinant human C1 inhibitor, asthma phenotyping, and assessing educational programs in allergy and immunology. (mayo.edu)

This organ, known as Jacobson's organ, consists of two elongated fluid-filled sacs that open into the nasal cavity and oral cavity. (petmassage.com)

This seems to regulate the size of the olfactory system, which has fascinating implications for understanding how many mammals possess a keener sense of smell than humans. (nih.gov)

Human olfactory system. (iiab.me)

Dogs, cats, and humans can lose their sense of smell (the technical term for not being able to smell is to be anosmic). (dogster.com)
This colorful, almost psychedelic image shows the entire olfactory epithelium, or "smell center," (green) inside the nasal cavity of a newborn mouse. (nih.gov)
Over the years, humans have grown to realize the importance of the dog's highly developed sense of smell and have employed dogs for many important tasks. (petmassage.com)
But their extensive nasal turbinates generally suggest that they have an acute sense of smell. (floofmania.com)
In humans, our sense of smell plays a role in about 80% of the things we taste. (floofmania.com)

To begin, dissociate the nasal brush biopsy into 8 milliters of RPMI media in a 15 milliliter conical tube by passing the cytology brush several times through a one milliliter large-bore pipette tip. (jove.com)

The conducting zone includes regions that do not participate in gas exchange, namely the nasal passage, trachea, main bronchi, intra-pulmonary bronchi and bronchioles. (stemcell.com)

The in vivo model of nasal microvascular leakage was used for the nasal allergic challenge in ovalbumin (OA)-sensitized guinea pigs, or nasal stimulation with leukotriene D4 (LTD4) in non-sensitized animals. (researchgate.net)

Anatomy13

Organisms1

Diseases7

Chemicals and Drugs5

Analytical, Diagnostic and Therapeutic Techniques and Equipment6

Phenomena and Processes3

Technology, Industry, Agriculture1

Information Science1

Health Care1

Epithelial20

Called the olfactory epithelium3

Airway epithelia2

Mucosa8

Chronic rhinosinusitis with nasal polyps1

Vitro2

Polyps4

Responsible for detec2

Tissues3

Bronchial epithelium1

Primary ciliary dy1

Biopsies3

Vaginal epithelium2

Neurons7

Small airway1

Nose7

Lavage fluid3

Neurotoxicity1

Turbinate Bones1

Cavity called1

Sensory4

Organoids1

Odors2

Inhalation4

Cell proliferation2

Secretions1

Olfaction2

0.051

Placode1

Secretion2

Cystic2

Cells19

Receptors8

Recurrence2

Lung1

Septum1

Nostrils2

Transient1

Strand breaks2

Exposure6

Respiratory system1

Molecules2

Inflammation1

Detects1

Secretory2

Anatomy1

Deposition2

Bony3

Vomeronasal organ1

Placebo2

Allergy2

Consists1

Mammals1

Olfactory system1

Smell5

Biopsy1

Pulmonary1

Vivo1