Human liver microsomes and recombinant cyp450 enzymes. Medical search. Frequent questions

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Anatomy11

Microsomes, Liver Microsomes Liver Hepatocytes Mitochondria, Liver Cell Line Cells, Cultured Intestines Cytosol Kidney Bile

Organisms15

Baculoviridae Insects Rats, Sprague-Dawley Rats, Inbred Strains Rats, Gunn Dogs Rabbits Rats, Wistar Rats, Inbred F344 Escherichia coli Euphorbia Haplorhini Macaca fascicularis Cricetinae Citrus paradisi

Diseases9

Liver Diseases Liver Neoplasms Liver Cirrhosis Fatty Liver Drug-Induced Liver Injury Liver Neoplasms, Experimental Carcinoma, Hepatocellular Liver Failure, Acute Liver Diseases, Alcoholic

Chemicals and Drugs156

Cytochrome P-450 Enzyme System Cytochrome P-450 CYP3A Aryl Hydrocarbon Hydroxylases Mixed Function Oxygenases Cytochrome P-450 CYP2D6 Cytochrome P-450 CYP1A2 Oxidoreductases, N-Demethylating Steroid 16-alpha-Hydroxylase Troleandomycin Glucuronides Ketoconazole Recombinant Proteins Glucuronosyltransferase Mephenytoin Steroid Hydroxylases Isoenzymes Quinidine Enzyme Inhibitors Sulfaphenazole Cytochrome P-450 CYP2E1 Cytochrome P-450 CYP1A1 Uridine Diphosphate Glucuronic Acid Phenacetin Midazolam Astemizole Orphenadrine NADP Coumarins Benzoflavones Oxidoreductases, O-Demethylating Chlorzoxazone DNA, Complementary NADPH-Ferrihemoprotein Reductase Sapogenins Proadifen Glucuronates Oxygenases Tolbutamide Mephobarbital Fluvoxamine Phenobarbital Dextromethorphan Diclofenac Ticrynafen Cytochromes b5 Hydroxytestosterones Triazolam Dextrorphan Cytochrome P-450 CYP2B1 7-Alkoxycoumarin O-Dealkylase Debrisoquin Safrole Gemfibrozil Alamethicin Perhexiline Nitrosamines Endosulfan Methylcholanthrene Pharmaceutical Preparations Aldrin Glucuronic Acid Bupropion Prodrugs Methadyl Acetate Phenytoin Butyrophenones Carboxylic Ester Hydrolases Recombinant Fusion Proteins Benzydamine Amitriptyline Imipramine Carboxylesterase Tranylcypromine Cytochrome-B(5) Reductase Methoxychlor Glutathione Acetonitriles Propiophenones Monoterpenes Sulfoxides DNA, Recombinant Sparteine Triazoles RNA, Messenger Oxidoreductases beta-Naphthoflavone Menthol Fenbendazole Antibodies Nortriptyline Flutamide Epoxy Compounds Testosterone Liver Extracts Carcinogens Designer Drugs Ethanolamines Cytochrome Reductases Dimethylnitrosamine Triacetoneamine-N-Oxyl Mefenamic Acid Carbamazepine Terfenadine Catechols Oxazines Acetaminophen Bilirubin Histamine H1 Antagonists Theophylline Terpenes Benzopyrenes Miocamycin Ditiocarb Mexiletine Hymecromone Pyridines Anti-Allergic Agents Proguanil Phenothiazines Trifluoperazine Sertraline Flavonoids DNA Glucose-6-Phosphatase Paroxetine Bile Acids and Salts Cotinine Benzopyrene Hydroxylase Dextropropoxyphene Antibodies, Monoclonal Fluoxetine Antidepressive Agents, Tricyclic Cimetidine Epoxide Hydrolases Antidepressive Agents, Second-Generation Monoamine Oxidase Omeprazole Warfarin Cholestanetriol 26-Monooxygenase Isoxazoles Serotonin Uptake Inhibitors Lignans Cresols Cetomacrogol Carbon Radioisotopes Flurbiprofen Alkane 1-Monooxygenase Benzphetamine Medetomidine Quinolines Plant Extracts Imidazoles Phthalazines Glutathione Transferase Zidovudine Indenes

Analytical, Diagnostic and Therapeutic Techniques and Equipment22

Chromatography, High Pressure Liquid Mass Spectrometry Liver Transplantation Chromatography, Liquid Tandem Mass Spectrometry Spectrophotometry, Ultraviolet Gas Chromatography-Mass Spectrometry Cloning, Molecular Spectrometry, Mass, Electrospray Ionization Magnetic Resonance Spectroscopy Liver Function Tests Liver Neoplasms, Experimental Metabolic Clearance Rate Blotting, Western Area Under Curve Electrophoresis, Polyacrylamide Gel Transfection Inhibitory Concentration 50 Drug Evaluation, Preclinical Models, Biological Drug Stability Administration, Oral

Phenomena and Processes41

Hydroxylation Dealkylation Biotransformation Kinetics Drug Interactions Stereoisomerism Oxidation-Reduction Substrate Specificity Metabolic Detoxication, Phase I Catalysis Molecular Structure Metabolic Detoxication, Phase II Metabolic Detoxication, Drug Liver Regeneration Species Specificity Enzyme Induction Amino Acid Sequence Dose-Response Relationship, Drug Base Sequence Methylation Metabolic Clearance Rate Herb-Drug Interactions Area Under Curve Protein Binding Hydrolysis Half-Life Structure-Activity Relationship Time Factors Hydrogen-Ion Concentration Polymorphism, Genetic Transfection Genetic Vectors Alkylation Gene Expression Inhibitory Concentration 50 Liver Circulation Food-Drug Interactions Molecular Weight Genotype Biocatalysis Gene Expression Regulation, Enzymologic

Disciplines and Occupations1

Immunochemistry

Technology, Industry, Agriculture1

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care1

Area Under Curve

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Microsomes, Liver Cytochrome P-450 Enzyme System Cytochrome P-450 CYP3A Aryl Hydrocarbon Hydroxylases Hydroxylation Dealkylation Mixed Function Oxygenases Microsomes Cytochrome P-450 CYP2D6 Biotransformation Cytochrome P-450 CYP1A2 Oxidoreductases, N-Demethylating Steroid 16-alpha-Hydroxylase Troleandomycin Glucuronides Ketoconazole Recombinant Proteins Glucuronosyltransferase Mephenytoin Steroid Hydroxylases Chromatography, High Pressure Liquid Liver Isoenzymes Quinidine Kinetics Drug Interactions Enzyme Inhibitors Sulfaphenazole Cytochrome P-450 CYP2E1 Cytochrome P-450 CYP1A1 Stereoisomerism Uridine Diphosphate Glucuronic Acid Phenacetin Midazolam Oxidation-Reduction Substrate Specificity Metabolic Detoxication, Phase I Astemizole Orphenadrine Mass Spectrometry Liver Diseases NADP Liver Neoplasms Coumarins Hepatocytes Benzoflavones Oxidoreductases, O-Demethylating Baculoviridae Chlorzoxazone Catalysis Liver Transplantation DNA, Complementary NADPH-Ferrihemoprotein Reductase Sapogenins Proadifen Glucuronates Chromatography, Liquid Liver Cirrhosis Oxygenases Tandem Mass Spectrometry Tolbutamide Molecular Structure Mephobarbital Fluvoxamine Phenobarbital Molecular Sequence Data Metabolic Detoxication, Phase II Dextromethorphan Diclofenac Ticrynafen Metabolic Detoxication, Drug Cytochromes b5 Hydroxytestosterones Liver Regeneration Species Specificity Triazolam Enzyme Induction Amino Acid Sequence Dextrorphan Fatty Liver Cytochrome P-450 CYP2B1 Insects 7-Alkoxycoumarin O-Dealkylase Dose-Response Relationship, Drug Rats, Sprague-Dawley Debrisoquin Safrole Mitochondria, Liver Rats, Inbred Strains Spectrophotometry, Ultraviolet Gemfibrozil Alamethicin Perhexiline Gas Chromatography-Mass Spectrometry Nitrosamines Endosulfan Methylcholanthrene Base Sequence Pharmaceutical Preparations Aldrin

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