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  • immunity
  • Because the HLA antigens are essential to immunity, identification aids in determination of the degree of tissue compatibility between transplant recipients and donors. (thefreedictionary.com)
  • immunotherapy
  • Cancer immunotherapy has focused on the identification of tumor-associated antigens that are expressed exclusively by cancer cells. (pnas.org)
  • conclude
  • We conclude that specific HLA antigens are not strongly associated with the illnesses of Gulf War veterans. (biomedsearch.com)
  • Conclusions: We conclude human NK cell activation contributes significantly to GalTKO.hCD46 pig endothelial injury and lung inflammation and show that expression of HLA-E is associated with physiologically meaningful protection of GalTKO.hCD46 cells and organs exposed to human blood. (uni-muenchen.de)
  • detection
  • Sputum, bronchoalveolar lavage (BAL), or urine obtained from 114 patients after solid organ (heart, kidney, liver, pancreas) transplantation were examined for the presence of Legionella by using the culture method (sputum, BAL), and the direct fluorescent antibody assay method (sputum, BAL), and by the detection of urinary antigen (urine) during the 4 months after transplantation. (asmscience.org)
  • Molecular
  • To study the intrinsic link between the deregulated signaling cascade present in many cancers and the ability of antigen processing to alert CTLs to such molecular events, we have investigated the structural and biophysical properties and structures of 3 HLA A2 phosphopeptide complexes derived from cell division cycle (CDC) 25b, β-catenin, and insulin receptor substrate (IRS) 2 and have compared them with the structures of their nonphosphorylated counterparts. (pnas.org)
  • methods
  • Methods: Lungs from pigs modified to express GalTKO.hCD46 (n=37) and GalTKO.hCD46.HLA-E (n=5) were harvested and perfused with human blood until failure or elective termination at 4hours. (uni-muenchen.de)