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  • HLAs
  • Diversity of HLAs in the human population is one aspect of disease defense, and, as a result, the chance of two unrelated individuals with identical HLA molecules on all loci is extremely low. (wikipedia.org)
  • interferon
  • By analogy to the behavior of other interferons and a class of nucleotidyl transferases on the polynucleotide-agarose chromatography, we suggest that the human leukocyte interferon having the polynucleotide-binding site is in a possibly "native" conformation and the loss of affinity for polynucleotide results from a degradative alteration of the native molecules. (pnas.org)
  • The easy separation of these two classes of human leukocyte interferon makes the purification procedures more rational and will facilitate the preparation of both subspecies to a high degree of molecular homogeneity. (pnas.org)
  • Chromosome
  • Any of several members of a system consisting of the gene products of at least four linked loci (A, B, C, and D) and a number of subloci on the sixth human chromosome that have been shown to have a strong influence on human allotransplantation, transfusions in refractory patients, and some disease associations. (thefreedictionary.com)
  • Patients
  • This chapter compares human leukocyte antigen (HLA) frequency and HLA haplotype frequency in Legionella -positive patients with frequencies in healthy individuals from a local panel (control group). (asmscience.org)
  • DAISY was a prospective observational study involving 1,770 unaffected children who were either first-degree relatives of patients with type 1 diabetes or who carried a high-risk human leukocyte antigen (HLA) genotype. (thefreedictionary.com)
  • diseases
  • NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
  • sciences
  • The vision of the NIEHS is to use environmental health sciences to understand human disease and improve human health. (nih.gov)
  • The National Institute of Environmental Health Sciences (NIEHS) is expanding and accelerating its contributions to scientific knowledge of human health and the environment, and to the health and well-being of people everywhere. (nih.gov)
  • Blood
  • The buffy coat is the thin layer of translucent cells suspended between the red blood cells and plasma of blood consisting of platelets & leukocytes(WBCs) in the blood. (scribd.com)