Embryonic Stem CellsPluripotent Stem CellsStem CellsInduced Pluripotent Stem CellsCell DifferentiationOctamer Transcription Factor-3Cell Culture TechniquesEmbryo ResearchEmbryo, MammalianStem Cell TransplantationCell LineageTeratomaEmbryoid BodiesCell LineStage-Specific Embryonic AntigensSOXB1 Transcription FactorsCells, CulturedGerm LayersFeeder CellsNuclear ReprogrammingHematopoietic Stem CellsEndodermNeural Stem CellsGene Expression Regulation, DevelopmentalHomeodomain ProteinsTotipotent Stem CellsKaryotypingCell ProliferationAdult Stem CellsStem Cell ResearchBone Morphogenetic Protein 4Gene Expression ProfilingRegenerative MedicineActivinsCoculture TechniquesReverse Transcriptase Polymerase Chain ReactionBiological MarkersMultipotent Stem CellsFlow CytometryMice, SCIDMyocytes, CardiacBlastocystCell DedifferentiationNeural PlateMesenchymal Stromal CellsCell SeparationTranscription FactorsNodal ProteinEpigenesis, GeneticSignal TransductionGreen Fluorescent ProteinsFibroblastsNeuronsLentivirusGene Expression RegulationEmbryo Culture TechniquesGene TargetingGerm CellsStem Cell NicheCulture Media, Serum-FreeCell SurvivalImmunohistochemistryHematopoiesisHematopoietic Stem Cell TransplantationMesenchymal Stem Cell TransplantationSOXF Transcription FactorsTissue EngineeringBlastocyst Inner Cell MassCloning, OrganismCell- and Tissue-Based TherapyCulture Media, ConditionedEmbryonal Carcinoma Stem CellsEmbryonic DevelopmentOligonucleotide Array Sequence AnalysisLeukemia Inhibitory FactorTransgenesGene ExpressionCell ShapeChimeraX Chromosome InactivationBone Morphogenetic ProteinsCell TransplantationMesodermPhenotypeRegenerationResearch Embryo CreationModels, BiologicalDNA MethylationMicroRNAsKruppel-Like Transcription FactorsEctodermDehumanizationCulture MediaGenetic VectorsCryopreservationRNA, MessengerBeginning of Human LifeHMGB ProteinsTime FactorsKaryotype