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  • importance
  • In addition to the recombinant DNA field, the analytical hybridization technique can be applied to the detection of polynucleotides of importance in the fields of human and veterinary medicine, agriculture, and food science, among others. (google.ca)
  • The adherence assay enriched for pO157 DNA indicating the importance of this plasmid for colonization of rectal epithelial cells. (frontiersin.org)
  • mammary gland
  • Scottish embryologist Ian Wilmut and his colleagues had taken a mammary gland cell from a six-year-old Scottish Finn Dorset ewe and, via a process known as "nuclear transfer," succeeded in placing the genetic material from that cell into a hollowed-out egg cell from a Scottish Blackface sheep. (apologeticspress.org)
  • genetically
  • So, using presently available in vitro fertilization techniques, they set out intentionally to create a "genetically matched" brother or sister for Molly-with the specific goal of using the newborn's stem cells (derived from the umbilical-cord blood shortly after birth) to treat Molly's condition. (apologeticspress.org)
  • The result suggests that, although Hwang deceived the world about achieving the first human cloning, his group was first to succeed in performing human parthenogenesis, which may offer a way of creating cells that are genetically matched to a woman for transplantation back into her body to treat degenerative diseases. (scientificamerican.com)
  • The claim went up in smoke in January of 2006 after a probe by the university concluded that Hwang had fabricated the evidence, which followed a similarly damning assessment of a landmark paper from the previous year in which the group falsely reported creating 11 cell lines genetically matched to their donors. (scientificamerican.com)
  • CEO, Xu Xiaochun, educated at Canadian and American universities, plans to produce cloned beef using genetically identical super-cattle to cater to the hugely successful Chinese middle class who enjoy the taste of Kobe beef. (hubpages.com)
  • Human cloning is the creation of a genetically identical copy (or clone) of a human. (wikipedia.org)
  • unethical
  • However, destroying new human lives for experimentation is immoral and unethical, and it is clear that the advances these researchers seek can probably be done better and sooner with adult stem cells. (illinoisrighttolife.org)
  • At this point, these groups have their work cut out for them as cloning people may well be determined to be unethical. (hubpages.com)
  • world's
  • On November 2015, a Chinese biotech company Boyalife Group announced that it will partner with Hwang's laboratory, Sooam Biotech, to open the world's largest animal cloning factory in Tianjin as early as 2016. (wikipedia.org)
  • Bioethics
  • Years earlier, in October of 1995, Clinton had established the National Bioethics Advisory Commission (NBAC) in light of bioethical concerns over research on humans. (scribd.com)
  • On May 12, 2006, Hwang was charged with embezzlement and bioethics law violations after it emerged much of his stem cell research had been faked. (wikipedia.org)
  • Nigel M. de S. Cameron, Ph.D., a bioethics scholar whose special focus is the relations of human values and public policy, joined the law school as university research professor of bioethics with responsibility for the development of the Institute. (wikipedia.org)
  • Hwang's
  • Jeffrey Janus, president and director of research for ISC, agrees that "Dr. Hwang's cells have characteristics found in parthenogenetic cells" but remains cautious, saying "it needs more study. (scientificamerican.com)
  • Hwang's next claim came only two months later in April 1999, when he announced the cloning of a Korean cow, Jin-i, also without providing any scientifically verifiable data. (wikipedia.org)
  • Hwang
  • In February 2011, Hwang visited Libya as part of a $133 million project in the North African country to build a stem cell research center and transfer relevant technology. (wikipedia.org)
  • His alleged success was touted as the fifth instance in the world in cow cloning, with a notable caveat: Hwang failed to provide scientifically verifiable data for the research, giving only media sessions and photo-ops. (wikipedia.org)
  • During that period, Hwang claimed to have created a BSE-resistant cow (which has not been verified) and also stated his intention to clone a Siberian tiger. (wikipedia.org)
  • Hwang claimed to have created eleven different patent-specific stem cell lines. (wikipedia.org)
  • Tianjin
  • The giant clone replication factory in Tianjin, a harbour town in the north of China, will be ready to go into production within seven months - June 2016. (hubpages.com)
  • sheep
  • That zygote-which then contained the full complement of 54 chromosomes (as if it had been fertilized by a sperm cell)-was placed into the uterus of a second Scottish Blackface sheep that served as a surrogate mother. (apologeticspress.org)
  • vitro
  • Even in the Petri dish, the fertilized egg created through in vitro fertilization continues to divide, with the number of cells doubling quickly. (childresearch.net)
  • donor
  • The National Marrow Donor Program website (www.marrow.org) lists quite a number of diseases currently treatable by stem cell transplants, including acute and chronic leukemias, Hodgkin's Disease and Non-Hodgkin's Lymphoma, sickle cell disease, and various cancers. (illinoisrighttolife.org)
  • Expertise in human egg biology led Kiessling to develop the country's first human egg donor program for stem cell research in 2000. (wikipedia.org)
  • moratorium
  • ban all federal funding for cloning research as well as asking for a temporary voluntary moratorium on cloning research by private institutions until more could be learned about the issue. (scribd.com)
  • researchers
  • However, because iPS can sometimes cause unexpected mutations in the cells, researchers have been seeking alternative methods. (medicalnewstoday.com)
  • Researchers and ethicists in the United States say they see no reason to fear the move would encourage the use of the technology to make cloned babies - something that most of the international biomedical community has agreed not to pursue. (abovetopsecret.com)
  • Based on meticulous mammalian study review, the researchers concluded that the rigorous procedures developed for mammalian reproduction held promise for practical application in human embryonic stem cell (hESC) line production. (wikipedia.org)
  • research
  • Ethical implications of cloning and stem cell research. (brainmass.com)
  • applications thus avoiding the controversy associated with opponents to stem cell research. (brainmass.com)
  • EDITOR'S NOTE: Two of the most hotly debated and currently controversial topics-in the fields of science, religion, ethics, and politics-are human cloning and stem-cell research. (apologeticspress.org)
  • The research " will lead inexorably to cloning to produce a live born child, " said bioethicist O. Carter Snead, of the University of Notre Dame, told Reuters . (chron.com)
  • Human cloning and embryonic stem cell research after Seoul. (iupui.edu)
  • Schwetz] contains the testimony and prepared statement of Bernard A. Schwetz, director of the Office for Human Research Protections, U.S. Department of Health and Human Services. (iupui.edu)
  • Pascal] contains the testimony and prepared statement of Chris B. Pascal, director of the Office of Research Integrity, U.S. Department of Health and Human Services. (iupui.edu)
  • Values in conflict] contains the document "Values in Conflict: Public Attitudes on Embryonic Stem Cell Research. (iupui.edu)
  • As stated in Executive Order 12975 by which the NBAC was organized, the purpose of this Commission was to recommend regulations on "bioethical issues arising from research on human biology and behaviour. (scribd.com)
  • The main argument for why cloning research should be continued is the possible benefits it can have. (scribd.com)
  • Those who opposed using embryonic stem cell research have showed the many benefits to humans from adult and cord blood stem cells. (illinoisrighttolife.org)
  • I think this is an extremely important-and solid-paper," says stem cell researcher Robert Lanza, vice president of research and scientific development at Applied Cell Technology, a regenerative medicine company headquartered in Alameda, Calif., who did not take part in the study. (scientificamerican.com)
  • PHILADELPHIA - (KRT) - In a move that could accelerate stem-cell research, the British government yesterday granted Newcastle University that country's first license to use cloning to create human stem cells. (abovetopsecret.com)
  • To all: This week two bills regarding human embryonic stem cell research and human cloning are likely to receive committee and floor action. (aproundtable.org)
  • Concerns: For the first time in state law, both bills provide an express intent to encourage research on human embryonic stem cells (even though it is limited to the federal registry). (aproundtable.org)
  • SB 210 is even less restrictive, because it would encourage human cloning research with private funds. (aproundtable.org)
  • But the stem cell research component was introduced at the end of September and came specifically from negotiations with Ohio Right to Life as a trade off to stand down on Issue 1. (aproundtable.org)
  • The corporation came into being some three years after the establishing of the International Consortium of Stem Cell Research (INCOSC) in China (a vast research and development laboratory covering 250 acres). (hubpages.com)
  • As the Boyalife Group states "INCOSC was established with the Participation of 7 large research institutes from Europe, USA and China," it can be assumed that the two anonymous stem cell laboratories are probably American. (hubpages.com)
  • Enact health care for all, stem cell research, human cloning. (wikipedia.org)
  • Kiessling currently conducts research at the Bedford Stem Cell Research Foundation. (wikipedia.org)
  • The need to conduct biomedical research in areas not funded by the federal government led to the incorporation of the Bedford Stem Cell Research Foundation. (wikipedia.org)
  • Kiessling is a member of the California (California Constitution Article XXXV) and Connecticut Stem Cell Research Advisory Boards, and a member of the Embryonic Stem Cell Research Oversight Committees (ESCROS) for Harvard University, Joslin Diabetes Center and Children's Hospital. (wikipedia.org)
  • He voted against a bill that allows stem cell research but prohibits human cloning. (wikipedia.org)
  • He was a professor of theriogenology and biotechnology at Seoul National University (dismissed on March 20, 2006) who became infamous for fabricating a series of experiments, which appeared in high-profile journals, in the field of stem cell research. (wikipedia.org)
  • The Korea Times reported on June 10, 2007, that Seoul National University fired him, and the South Korean government canceled his financial support and barred him from engaging in stem cell research. (wikipedia.org)
  • He's been an outspoken proponent of the Catholic Church's positions in opposition to human cloning and embryonic stem cell research. (wikipedia.org)
  • Gene Patents Patents for human genetic material grant exclusivity over naturally occurring sequences of human genes and their effect on research and diagnosis. (wikipedia.org)
  • The International Society for Stem Cell Research (ISSCR) is an independent 501(c)(3) nonprofit organization based in Skokie, Illinois, United States. (wikipedia.org)
  • The organization's mission is to promote and foster the exchange and dissemination of information and ideas relating to stem cells, to encourage the general field of research involving stem cells, and to promote professional and public education in all areas of stem cell research and application. (wikipedia.org)
  • In June 2003, the International Society for Stem Cell Research held its first convention. (wikipedia.org)
  • 1971
  • Americans United for Life (AUL) is an American pro-life public interest law firm and advocacy group based in Washington, D.C. Founded in 1971, the group advocates protection of human life at all stages of life, from conception to death, and is involved in the related issues of health and biotechnology. (wikipedia.org)
  • Another Nobel Laureate, James D. Watson, publicized the potential and the perils of cloning in his Atlantic Monthly essay, "Moving Toward the Clonal Man", in 1971. (wikipedia.org)
  • make
  • The Wright brothers took off and this has actually managed to make embryonic stem cells. (medicalnewstoday.com)
  • In papers published this week in Nature , another Japanese team says that it has come up with a surprisingly simple method - exposure to stress, including a low pH - that can make cells that are even more malleable than iPS cells, and do it faster and more efficiently. (cbc-network.org)
  • legislation
  • However, around the world, many countries began producing legislation that forbade human cloning. (scribd.com)
  • Though neither of these attempts were successful, both show that attempts on human cloning will still occur as long as there is no worldwide legislation. (scribd.com)
  • genetic material
  • Next, they removed most of the DNA from each egg and replaced the genetic material with DNA from other peoples' skin cells. (kwit.org)
  • genes
  • This report pioneered the importance of naturally occurring retrovirus sequences in human genes, now thought to be important to the genetic plasticity involved in human evolution and biology. (wikipedia.org)
  • sperm
  • When a chromosome from a sperm cell joins with that of an egg, these single nucleotide polymorphisms (SNPs or "snips") tend not to match each other. (scientificamerican.com)
  • refers
  • Specifically, this refers to efforts to culture, for example, skin for the treatment of burns, cornea for cataracts, myocardial cells for myocardial disorders, bone and cartilage for motor disorders, neurocytes for neurological disorders, insulin-secreting cells for diabetes, among others. (childresearch.net)
  • holy grail
  • It's been a holy grail that we've been after for years," says Dr. John Gearhart , a stem cell pioneer at the University of Pennsylvania. (kwit.org)
  • scientist
  • This is a huge scientific advance," said Dr. George Daley , a Harvard stem cell scientist who wasn't involved in the work. (kwit.org)
  • George Daley
  • Later, during a chance discussion with European colleagues, stem cell researcher George Daley of Children's Hospital Boston and the Harvard Stem Cell Institute learned that they had received samples of the cell line before the work was retracted. (scientificamerican.com)
  • cDNA
  • Multiple cloning sites are sometimes used to ensure that the fragments are inserted in all three possible reading frames so that the cDNA fragment is translated in the proper frame. (wikipedia.org)
  • proteins
  • Clathrin coated vesicles enable neurotransmitter receptors and other proteins to be endocytosed or taken up across neuronal membranes and across the membranes of other types of cells. (wikipedia.org)
  • The proteins were called Ten-ms in zebrafish, teneurins in chicken, Ten-m1-4, Odz1-4, Ten-m/Odz1-4, DOC4 in mouse, neurestin in rat, and teneurin or Odz in human. (wikipedia.org)
  • Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter for example, the breaking down of glucose to pyruvate, by cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. (wikipedia.org)
  • Other proteins have structural or mechanical functions, such as those that form the cytoskeleton, a system of scaffolding that maintains the cell shape. (wikipedia.org)
  • Proteins are also important in cell signaling, immune responses, cell adhesion, active transport across membranes, and the cell cycle. (wikipedia.org)
  • The Atg proteins regulate autophagy, which is a lysosomal degradation pathway required for maintaining cell health, surviving periods of nutrient deprivation and also plays a role in cancer, neurodegeneration and immune responses to a diverse range of pathogens. (wikipedia.org)
  • 1999
  • Going into the 1999 election with new leadership and executive, the party achieved limited media attention by conducting a demonstration at Queen's Park featuring three "cloned sheep" to represent Progressive Conservative leader Mike Harris, Liberal leader Dalton McGuinty and New Democratic Party leader Howard Hampton. (wikipedia.org)
  • inhibition
  • One more rising problem is that Kendall Reyes Chargers Jersey , in addition to im pting the advancent and survival of aberrant cells, CR and mTOR inhibition may well also impt the stem mobile partnt and enrich maintenance or fix of tissues. (xobor.com)
  • Over-expression of PPARδ also sensitised THP-1 cells to phorbol ester and correspondingly, inhibition of PPARδ by anti-sense RNA completely abolished this response. (biomedcentral.com)
  • Exogenous PUFA and a TRPC3 antagonist regularly attenuated breasts cancer tumor cell proliferation and migration, recommending a mechanism where PUFA restrains the breasts cancer partially via its inhibition of TRPC stations. (cancercurehere.com)
  • membranes
  • Jesse F. McClendon made substantial contributions in a variety of fields, including invertebrate zoology, nutrition, life processes of cell membranes, the importance of pH control, the role of iodine in human health, and specifically its relation to prevention of goiters. (wikipedia.org)
  • Their main structural uses are as part of biological membranes both internal and external, such as the cell membrane, or as a source of energy. (wikipedia.org)
  • coli cells
  • The yield and productivity of gamma-aminobutyric acid might be significantly improved if the overexpressed GadB in E. coli cells can be excreted outside, where it can directly transforms monosodium glutamate to gamma-aminobutyric acid. (springeropen.com)
  • nuclear
  • It has been associated with heterochromatin and PML-NBs (Promyelocytic Leukaemia nuclear bodies) and has been implicated in many nuclear processes including transcription and cell cycle regulation. (wikipedia.org)
  • When the cell is treated with TGF-β, HIPK2, a nuclear kinase, phosphorylates Daxx and the activated Daxx in turn activates the JNK pathway (see "The Daxx Pathway" figure). (wikipedia.org)
  • inhibitory
  • Yilmaz and colleagues confird that CR, through its inhibitory consequences of mTOR signaling in Pah cells adja cent to intestinal stem cells, preserves and even enriches intestinal stem cells. (xobor.com)
  • Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in human cortex, it has been considered as a food constituent in Europe and a dietary supplement in USA (Boonstra et al. (springeropen.com)
  • HeLa
  • WIPI2 mRNA is readily detectable in several commonly used laboratory cell lines (HEK293A, HeLa, A431) and several cancer cell lines, while WIPI1 expression is limited to cancer cells. (wikipedia.org)
  • macrophages
  • PPARδ (NR1C2) promotes lipid accumulation in human macrophages in vitro and has been implicated in the response of macrophages to vLDL. (biomedcentral.com)
  • embryonic
  • This proto-oncogene may play a role in the regulation of embryonic development and cell growth. (wikipedia.org)
  • Other studies showed that lack of Daxx gene caused a higher apoptotic rate in embryonic stem cells. (wikipedia.org)
  • serum
  • Components and strategies Cell lifestyle MCF-7 cells had been grown up in DMEM moderate filled with 10% fetal leg serum and 1% penicillin/streptomycin serum as defined (9). (cancercurehere.com)
  • The heterodimer also stimulated cAMP production and thymidine incorporation by cultured thyroid cells and increased serum thyroxine levels in TSH-suppressed rats in vivo. (jci.org)
  • HAP1 cells are grown in Iscove's Modified Dulbecco's Medium (IMDM) in the presence of 10% fetal calf serum and penicillin/ streptomycin. (horizondiscovery.com)
  • functional
  • Within this research, we discovered the functional appearance of TRPC3 in individual MCF-7 breasts cancer tumor cell-mediated Ca2+ entrance. (cancercurehere.com)
  • pancreas
  • A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. (wikipedia.org)
  • regulation
  • It is involved in the regulation of adenine nucleotide composition within a cell by catalyzing the reversible transfer of the terminal phosphate group between ATP and AMP. (mybiosource.com)
  • Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells. (wikipedia.org)
  • Caspase
  • Per usual in non-apoptotic growing cells caspase activated dnase is held in check inactivated in the cytoplasm thanks to the association with its inhibitor, inhibitor of caspase-activated DNase (ICAD) also known as DNA fragmentation factor 45 kDa (DFF45). (wikipedia.org)
  • Caspase-3 is activated in the apoptotic cell. (wikipedia.org)
  • grown
  • Then the cells are grown on a dish with the medium that the antibiotic is resistant to and if the insertion was successful, then cells will grow. (macalester.edu)
  • Metabolism
  • Metabolism (from Greek: μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms. (wikipedia.org)
  • The word metabolism can also refer to the sum of all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism. (wikipedia.org)
  • Amino acids also contribute to cellular energy metabolism by providing a carbon source for entry into the citric acid cycle (tricarboxylic acid cycle), especially when a primary source of energy, such as glucose, is scarce, or when cells undergo metabolic stress. (wikipedia.org)
  • mutation
  • All HAP1 knockout cell lines are validated by PCR amplification and Sanger Sequencing to confirm the mutation at the genomic level. (horizondiscovery.com)
  • Customers obtain a clonal HAP1 cell line, bearing a frameshift mutation in an exon of the gene of interest. (horizondiscovery.com)
  • The mutation is described in the clone datasheet enclosed upon shipment and can be verified by a PCR on genomic DNA followed by Sanger sequencing. (horizondiscovery.com)
  • Mutation in the TENM3/ODZ3 gene in humans has been associated with the eye condition, microphthalmia. (wikipedia.org)
  • morphology
  • Specially M Wnt cells, cloned from a spontaneous mammary tumor from a MMTV Wnt 1 transgenic mouse, ow a senchy mal morphology, stably convey stem cell markers Manti Te'o Chargers Jersey , and swiftly create claudin reduced maArlen Booth s Cocaine Coma provides an important social mentary, exploring many societal problems while grounding itself in a story of an ordinary, middle class Chicago family to which anyone could relate. (xobor.com)
  • HAP1 cells are adherent with fibroblast-like morphology. (horizondiscovery.com)
  • expression
  • Both mouse and human atherosclerotic lesions show a high level of PPARγ expression and these findings provoked intense interest in the regulatory actions of PPARs in monocyte-macrophage biology. (biomedcentral.com)
  • Species
  • The formerly designated Borrelia burgdorferi has now been subdivided into multiple Borrelia species, including three that cause human infection. (asmscience.org)
  • normally
  • This discovery changed the current thinking about cancer from a model wherein cancer is caused by a foreign substance (a viral gene) to one where a gene that is normally present in the cell can cause cancer. (wikipedia.org)
  • This pathway normally regulates stress-induced cell death. (wikipedia.org)