• Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)
  • The endocervix is lined by columnar mucinous epithelium and in continuity with vaginal mucosa, the ectocervix is lined by squamous epithelium. (cytojournal.com)
  • The region where there is a transition from squamous to columnar epithelium in cervix is transformation zone. (cytojournal.com)
  • Squamous Dysplasia Cervix is a continually mentioned analysis clearly because it is of interest when considering Cervicalis Dysplasia, Define Cervical Dysplasia, and Define Dysplasia. (cervical-dysplasia-cure.com)
  • Could this be a problem: Squamous Dysplasia Cervix? (cervical-dysplasia-cure.com)
  • Penile squamous cell carcinoma (PSCC) is an orphan malignancy with poorly understood biology and suboptimal systemic therapy. (oncotarget.com)
  • The biology and drivers of penile squamous cell carcinoma (PSCC), an orphan disease, are poorly understood. (oncotarget.com)
  • A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. (lookformedical.com)
  • Approximately 11% of those that develop mild dysplasia or low-grade squamous intraepithelial lesions (LSIL) will progress to severe dysplasia or high-grade squamous intraepithelial lesions (HSIL), and an equal fraction will further progress to invasive carcinoma [ 2 ]. (biomedcentral.com)
  • Few diagnostic and prognostic biomarkers are available for head-and-neck squamous cell carcinoma (HNSCC). (biomedcentral.com)
  • Analysis of TCGA pan-cancer data revealed significant overexpression of CASC9 across different other entities including bladder, liver, lung and stomach cancers and especially in squamous cell carcinoma (SCC) of the lung. (biomedcentral.com)
  • By RT-qPCR analysis we furthermore detected stronger CASC9 overexpression in pure SCC of the urinary bladder and mixed urothelial carcinoma with squamous differentiation than in pure urothelial carcinomas. (biomedcentral.com)
  • Cancer Lett, 300:215-224.doi:10.1016/j. squamous cell carcinoma in north-eastern Iran. (who.int)
  • Global burden of HPV-attributable squamous cell carcinoma of the anus in 2020, according to sex and HIV status: A worldwide analysis. (who.int)
  • HPV infections have received particular attention in recent years, as high-risk strains have been linked to some cases of oral squamous cell carcinoma. (medscape.com)
  • WB: HEK293T, HAP1 and HeLa whole cell lysate. (abcam.com)
  • Flow Cyt: HeLa cells. (abcam.com)
  • ICC/IF: HeLa, NIH/3T3, whole cell. (abcam.cn)
  • IP: HeLa whole cell lyaste. (abcam.cn)
  • ICC/IF: HeLa cell line treated with TGF-beta. (abcam.com)
  • IP: HeLa and NIH/3T3 whole cell lysates. (abcam.com)
  • We cultivated human lung epithelial A549 cells (ATCC CCL-185), human hepatoma Huh7 cells ( 13 ), human cervix carcinoma HeLa cells (ATCC CCL-2), African green monkey kidney Vero cells (ATCC CCL-81), and transformed human dermal fibroblast cultures ( 14 ) in Dulbecco modified eagle medium supplemented with 10% fetal calf serum at 37°C and 5% CO 2 . (cdc.gov)
  • Three human cervix cancer cell lines (HeLa, Me180, and SiHa) were used. (e-roj.org)
  • G0-G1 phase cells were increased in HeLa and Me180 by 5 µM TRO for 24 hours, but those were not increased in SiHa. (e-roj.org)
  • 13. BK virus and its variants: association with tumors and transformed cells. (crsociety.org)
  • Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
  • Malignant tumors consist of cancer cells and tumor-associated host cells, both participating in invasion and distant metastasis. (biomedcentral.com)
  • Tumors or cancer of the UTERINE CERVIX. (lookformedical.com)
  • whole-body (18)f-fdg pet/ct for m staging in the patient with newly diagnosed nasopharyngeal carcinoma: who needs? (liverpool.ac.uk)
  • although whole-body fluorine-18 fluorodeoxyglucose ((18)f-fdg) positron emission tomography (pet)/computed tomography (ct) ((18)f-fdg pet/ct) is commonly used for m staging of newly diagnosed nasopharyngeal carcinoma (npc), some patients may not benefit from this procedure. (liverpool.ac.uk)
  • HHV-4, also known as Epstein-Barr virus (EBV), causes the primary infection infectious mononucleosis , and it is implicated in various diseases, such as African Burkitt lymphoma , other immunoproliferative disorders, and nasopharyngeal carcinoma. (medscape.com)
  • and or tumor cells infected with oncolytic viruses release PAMPs, which increases immune responses (217, 218). (azd1152.com)
  • The results of phase I and II trials showed that the use of Newcastle virus-infected tumor cells reduced recurrence and increased OS in CRC patients (44, 219). (azd1152.com)
  • A second concern is usually cytokine release syndrome due to the CAR-T cells activation following binding to antigens in both tumor cells and normal cells (226). (azd1152.com)
  • Many of the current efforts regarding anti-cancer drug development are focused on directing tumor cells to undergo apoptosis. (mdpi.com)
  • Possible mechanisms for overcoming the resistance of HPV-infected tumor cells to anticancer drugs will be discussed. (mdpi.com)
  • Reishi mushroom cancer research has noted that the active compounds in the mushroom have activity against tumor cells. (naturesrise.com)
  • Such cells are described as disseminated tumor cells (DTC) (Sosa et al. (biomedcentral.com)
  • 2014 ) or sometimes as circulating tumor cells (CTC) (Kim et al. (biomedcentral.com)
  • A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. (lookformedical.com)
  • A cell line derived from cultured tumor cells. (lookformedical.com)
  • CIN 3 Severe Cervical Dysplasia is a normally mentioned issue considering that it is crucial when considering CIN I Mild Dysplasia, CIN III Severe Dysplasia To Carcinoma In Situ, and CIN1 Dysplasia. (cervical-dysplasia-cure.com)
  • Also, our mutants induced proliferation, glucose uptake, inhibited the migration of 293T cells and affected the responsiveness of the cells to cisplatin and radiation. (scielo.br)
  • Bosutinib is a potent inhibitor of CML cell proliferation in vitro and has demonstrated promising activity in CML patients resistant or intolerant to IM as well as in newly diagnosed patients with chronic phase CML (CML-CP). (mdm2-receptor.com)
  • Tight control of the cell cycle in eukaryotic cells exists to control proliferation, differentiation or apoptosis. (benthamscience.com)
  • However, the underlying mechanisms involved in the induction of genomic instability, genotoxicity, mutations and consequent increased cell proliferation are still a matter of intense research. (benthamscience.com)
  • 4.2 Adoptive T Cell Therapy Take action is a malignancy immunotherapy method in which T cells are collected from your tumor, lymph nodes, or peripheral blood of a patient and returned Vanin-1-IN-1 to the patients body after proliferation and selection of tumor-specific T cells. (azd1152.com)
  • EGFR activation signals multiple downstream signaling cascades such as the Ras - ERK, PI3-K - Akt, Jak - STAT and PKC pathways that help in growth and proliferation of cells. (thermofisher.com)
  • One compelling idea to explain the Warburg effect is that the altered metabolism of cancer cells confers a selective advantage for survival and proliferation in the unique tumor microenvironment. (pharmaceuticalintelligence.com)
  • A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. (cancerindex.org)
  • chronic myeloid leukemia (cml) is characterized by increased and unregulated proliferation of granulocytic lineage in the bone marrow and presence of these immature myeloid cells in the peripheral blood with presence of philadelphia (ph) chromosome. (liverpool.ac.uk)
  • Effects of lncRNA overexpression or downregulation on cell proliferation, clonogenicity, migration and chemosensitivity were studied in HNSCC cell lines. (biomedcentral.com)
  • Differentiation and apoptosis have cell cycle withdraw in common, while cancer and degenerative processes both show altered control of the cell cycle. (benthamscience.com)
  • Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma. (cancerindex.org)
  • If one takes the author's recommendations, it takes just a couple of months to establish resistance to human papilloma virus. (cure-cervical-dysplasia-naturally.com)
  • human papilloma virus creates cervical dysplasia, cervical cancer cells, genital blemishes, plantar moles, losing unborn babies, the inability to conceive and also penile cancer. (cure-cervical-dysplasia-naturally.com)
  • Exactly what matters is how you make use of such data just like hundreds of others who have removed human papilloma virus. (cure-cervical-dysplasia-naturally.com)
  • Right here is the situation, this publication has to do with recovery from HPV, however it is not just concerning human papilloma virus. (cure-cervical-dysplasia-naturally.com)
  • HPV is comparable since human papilloma virus is simply an additional infection. (cervical-dysplasia-natural-cure.com)
  • Yet someone may avoid additional exposure and future human papilloma virus infections. (cervical-dysplasia-natural-cure.com)
  • This easy-read book offers valid encouragement to women diagnosed with human papilloma virus. (cervical-dysplasia-natural-cure.com)
  • I am so happy I reviewed it a number of months back, because I valued her frankness and also concur totally that human papilloma virus is a virus, not an ethical judgment. (cervical-dysplasia-natural-cure.com)
  • Majority of SCC are human papilloma virus (HPV) positive. (cytojournal.com)
  • Papiloma Virus is a recurring question due to the reason that it concerns Signs Of Human Papilloma Virus, Signs Of Human Papillomavirus Infection, and Slightly Abnormal Pap Cells. (pap-cures-naturally.com)
  • The longer an individual has human papilloma virus, the more likely it can create cervical damage. (pap-cures-naturally.com)
  • The book's writer shares just how she normally reversed the signs and symptoms of HPV virus and also entirely healed her very own body of the human papilloma virus infection by strengthening her body's immune response. (pap-cures-naturally.com)
  • Human papilloma virus is similar since HPV is simply an additional viral infection. (cervical-dysplasia-cure.com)
  • Nonetheless, human papilloma virus is much better at concealing from your body's immune system compared to the cold infections. (cervical-dysplasia-cure.com)
  • So you should persist harder to develop resistance to human papilloma virus. (cervical-dysplasia-cure.com)
  • If someone takes the author's advice, it requires just a couple of months to generate resistance to human papilloma virus. (cervical-dysplasia-cure.com)
  • It has to do with acknowledging human papilloma virus as an outstanding opportunity to take responsibility for our own health and wellness. (cervical-dysplasia-cure.com)
  • When seen from this perspective, a person could be thankful for human papilloma virus. (cervical-dysplasia-cure.com)
  • We treated Huh7 cells with recombinant human IFN-α2a (PBL Assay Science, https://www.pblassaysci.com ) or recombinant human IFN-γ (R&D Systems, https://www.rndsystems.com ) 16 h before and 2 h after infection. (cdc.gov)
  • To test antivirals, we treated Huh7 cells with ribavirin (Sigma-Aldrich, https://www.sigmaaldrich.com ) or favipiravir/T-705 (BioVision, https://www.biovision.com ) 2 h after infection. (cdc.gov)
  • Infection with certain types of human papillomavirus (HPV), while a necessary cause of cervical cancer, does not guarantee an elevated risk of malignancy. (biomedcentral.com)
  • Oncolytic virotherapy for cancer treatment utilizes naturally occurring or engineered viruses for selective infection and cancer cell death without any adverse effect on normal cells. (oncotarget.com)
  • ebv reactivation in latently infected b cells is essential for persistent infection whereby b cell receptor (bcr) activation is a physiologically relevant stimulus. (liverpool.ac.uk)
  • [ 5 , 6 ] In a localized primary infection, the virus penetrates the mucosal epithelium and invades the cells of the basal layer, where the viral DNA inserts into the host DNA. (medscape.com)
  • Hepatocellular Carcinomas from Iran: Evidence study of lung cancer among European asphalt carcinoma among postmenopausal women in the for Lack of Association between HBV Genotype workers. (who.int)
  • The cellular FLICE-inhibitory protein (c-FLIP) is a modulator of death receptor-mediated apoptosis and plays a major role in T- and B-cell homeostasis. (ashpublications.org)
  • Recombinant full length protein corresponding to Human Hsp90 alpha. (abcam.com)
  • Two biochemical processes, protein phosphorylation/dephosphorylation and ubiquitin-mediated degradation drive cell cycle control. (benthamscience.com)
  • By 5 µM TRO for 24 hours, the mRNA, protein expression and activity of catalase were increased in all three cell lines. (e-roj.org)
  • In addition, mannosebinding-lectin (MBL) is an epithelial-cell associated host protein that binds to Candida mannan, activates complement, and thus inhibits Candida growth. (paperzz.com)
  • This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. (cancerindex.org)
  • E7 from human papil omavirus type 16 cooperate to cancer: the European prospective investigation into doi:10.1093/carcin/bgp321 PMID:20047954 target the PDZ protein Na/H exchange regulatory cancer and nutrition study. (who.int)
  • These compounds play a crucial role in Reishi's cancer benefits-they inhibit cancer cells' growth and invasive properties. (naturesrise.com)
  • An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST. (lookformedical.com)
  • Lung cancer cells induce senescence and apoptosis of pleural mesothelial cells via transforming growth factor-beta1. (cellosaurus.org)
  • check the tag ADOLESCENCE HN - 2008 BX - Nutrition in Adolescence FX - Adolescent Nutrition Physiology MH - Peritoneal Stomata UI - D054048 MN - A01.047.025.600.700 MN - A10.810 MS - Natural openings in the subdiaphragmatic lymphatic plexus in the PERITONEUM, delimited by adjacent mesothelial cells. (bvsalud.org)
  • In human colon cancer xenograft model, a single intratumoral inoculation of the recombinant Raccoonpox virus, in combination with 5-fluorocytosine administration, produced relevant tumor growth control. (oncotarget.com)
  • E6 and Metabolic syndrome and risks of colon and rectal renal cell carcinoma. (who.int)
  • Herpesvirus type 2: Association with carcinoma of the cervix. (microbiologyresearch.org)
  • epstein-barr virus (ebv) is a human γ-herpesvirus associated with cancer, including burkitt lymphoma, nasopharyngeal, and gastric carcinoma. (liverpool.ac.uk)
  • Members of the human herpesvirus (HHV) and human papillomavirus (HPV) families cause the most common primary viral infections of the oral cavity. (medscape.com)
  • A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. (lookformedical.com)
  • A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
  • A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (lookformedical.com)
  • An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. (lookformedical.com)
  • HSD17B2 is expressed in the human endometrium and cervix among other tissues. (wikipedia.org)
  • We were interested in determining if any quantitative differences existed in the expression of E7 mRNA in cells from women with normal epithelium and precancerous lesions. (biomedcentral.com)
  • In HHV-1 and HHV-2 oral infections, viral replication within the oral epithelium may cause lysis of epithelial cells, with vesicle formation. (medscape.com)
  • A multitude of pathways control cyclin-dependent kinase activities as the major event for cell cycle progression. (benthamscience.com)
  • In addition, some of your body's cells are facultative anaerobes, retaining one of these ancient pathways for short-term, emergency use. (psychosocialsomatic.com)
  • Although humans are obligate aerobes, our muscle cells have not given up on ancient pathways which allow them to keep producing ATP quickly when oxygen runs low. (psychosocialsomatic.com)
  • Although our emphasis on the Warburg effect reflects the focus of the field, we would also like to encourage a broader approach to the study of cancer metabolism that takes into account the contributions of all interconnected small molecule pathways of the cell. (pharmaceuticalintelligence.com)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • Top pathways upregulated in both the kinase activity and gene expression platforms were PTEN, STAT3, GNRH, IL-8 and B cell receptor signaling. (oncotarget.com)
  • These compounds have about one-fifth the progestational activity of progesterone in humans and other species. (wikipedia.org)
  • C. albicans adheres in significantly high numbers to such cells compared with non-C. albicans Candida species. (paperzz.com)
  • Lung cancer is divided into two major groups: non small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). (scielo.br)
  • 2004) Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer. (scielo.br)
  • 2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. (scielo.br)
  • Carcinoma cervix is not the only cancer caused by HPV. (cytojournal.com)
  • Influential research by Warburg and Cori in the 1920s ignited interest in how cancer cells' energy generation is different from that of normal cells. (researchgate.net)
  • They observed high glucose consumption and large amounts of lactate excretion from cancer cells compared with normal cells, which oxidised glucose using mitochondria. (researchgate.net)
  • It was therefore assumed that cancer cells were generating energy using glycolysis rather than mitochondrial oxidative phosphorylation, and that the mitochondria were dysfunctional. (researchgate.net)
  • Advances in research techniques since then have shown the mitochondria in cancer cells to be functional across a range of tumour types. (researchgate.net)
  • This review will discuss the metabolic reprogramming of cancer, possible explanations for the high glucose consumption in cancer cells observed by Warburg, and suggest key experimental practices we should consider when studying the metabolism of cancer. (researchgate.net)
  • The Pap test is a cervical cancer prevention test that tracks preneoplastic changes in cervical epithelial cells. (mdpi.com)
  • They tested each on human cancer cell lines of the larynx, cervix, liver and breast. (cancerdefeated.com)
  • The researchers found that both the extracts and the pure isolated compounds showed "strong anti-tumor activities" against all of the cancer cell lines in the study. (cancerdefeated.com)
  • Other research groups found that ethanolic extracts of black lily showed anti-tumor activity against breast cancer and leukemia cells. (cancerdefeated.com)
  • The first part of the study involved testing GZ17 on an aggressive form of human prostate cancer in a cell culture at varying doses. (cancerdefeated.com)
  • When the three compounds were applied to the cancer cells individually there wasn't much response. (cancerdefeated.com)
  • The reishi mushroom also plays a crucial role in fighting off cancer cells. (naturesrise.com)
  • MMP is an enzyme that facilitates the spread of cancer cells by breaking down the insoluble barriers in the body. (naturesrise.com)
  • Reishi mushrooms also limit the attachment of cancer cells (2) to the lining of blood vessels and stop their spread through the bloodstream. (naturesrise.com)
  • Normal cells transform into cancer cells due to mutations in their genes. (naturesrise.com)
  • Polysaccharides also promote a normal cell turnover, maintaining overall wellness in the body-this also plays a crucial role in helping reishi mushrooms fight cancer. (naturesrise.com)
  • The spores of Ganoderma lucidum have long-chain fatty acids that fight cancer cells. (naturesrise.com)
  • Cancer Cell Metabolism. (pharmaceuticalintelligence.com)
  • In this Essay, we re-examine the Warburg effect and establish a framework for understanding its contribution to the altered metabolism of cancer cells. (pharmaceuticalintelligence.com)
  • It is hard to begin a discussion of cancer cell metabolism without first mentioning Otto Warburg. (pharmaceuticalintelligence.com)
  • He found that, even in the presence of ample oxygen, cancer cells prefer to metabolize glucose by glycolysis, a seeming paradox as glycolysis, when compared to oxidative phosphorylation, is a less efficient pathway for producing ATP (Warburg, 1956). (pharmaceuticalintelligence.com)
  • In this Essay, we discuss the possible drivers, advantages, and potential liabilities of the altered metabolism of cancer cells (Figure 1). (pharmaceuticalintelligence.com)
  • Drivers (A and B). The metabolic derangements in cancer cells may arise either from the selection of cells that have adapted to the tumor microenvironment or from aberrant signaling due to oncogene activation. (pharmaceuticalintelligence.com)
  • Advantages (C-E). The altered metabolism of cancer cells is likely to imbue them with several proliferative and survival advantages, such as enabling cancer cells to execute the biosynthesis of macromolecules (C), to avoid apoptosis (D), and to engage in local metabolite-based paracrine and autocrine signaling (E). Potential Liabilities (F and G). This altered metabolism, however, may also confer several vulnerabilities on cancer cells. (pharmaceuticalintelligence.com)
  • For example, an upregulated metabolism may result in the build up of toxic metabolites, including lactate and noncanonical nucleotides, which must be disposed of (F). Moreover, cancer cells may also exhibit a high energetic demand, for which they must either increase flux through normal ATP-generating processes, or else rely on an increased diversity of fuel sources (G). (pharmaceuticalintelligence.com)
  • HPV, a sexually-transmitted problem that could result in cervical cancer cells, is much more common compared to what most people normally believe. (cervical-dysplasia-cure.com)
  • The anticancer efficacy of GTB-NLCs was evaluated using 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyltetrazolium bromide cytotoxicity and flow cytometry on MCF-7 breast cancer cell lines. (bvsalud.org)
  • Also, gefitinib is nonselective for cancer as well as noncancer cells, leading to toxicity on other organs. (bvsalud.org)
  • The prepared formulation was tested for its drug release, stability and efficacy on breast cancer cell lines as well as toxicity using various methods. (bvsalud.org)
  • It was observed that the prepared formulation not only improved bioavailability but also improved the targeting as more gefitinib entered the cancer cells when present in the formulation, decreasing the toxicity of gefitinib on other organs. (bvsalud.org)
  • TRO has antiproliferative activity on many kinds of cancer cells via G1 arrest. (e-roj.org)
  • We investigated the effect of TRO on radiation sensitivity in cancer cells in vitro . (e-roj.org)
  • Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). (cellosaurus.org)
  • Establishment of a human lung alveolar cancer cell strain and its characteristics. (cellosaurus.org)
  • Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A. An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines. (cellosaurus.org)
  • Next-generation characterization of the Cancer Cell Line Encyclopedia. (cellosaurus.org)
  • Via direct actions on cancer cells and indirect actions on the tumor microenvironment, radiation has the potential to enhance epithelial-to-mesenchymal transition, invasion, migration, angiogenesis and metastasis. (biomedcentral.com)
  • Metastatic cancer cells are released from the primary tumor or from other metastases, at an undefined moment of its development, to arrive in the circulation and home at distant sites, where the ecosystem permits them to survive and either remain dormant as micro-metastases or grow to form macro-metastases (Mareel et al. (biomedcentral.com)
  • There is good evidence that cancer cells disseminate from the primary site early during tumor development (Hosseini et al. (biomedcentral.com)
  • Recruitment of CD11b + CD11c + myelomonocytic cells to the metastatic site was also found after whole thorax irradiation at a dose of 15 Gy of mice that significantly enhanced seeding and metastatic growth of intravenously injected cancer cells. (biomedcentral.com)
  • It represents a large group of epithelial lung malignancies which can be divided into two clinical groups: SMALL CELL LUNG CANCER and NON-SMALL-CELL LUNG CARCINOMA . (lookformedical.com)
  • These molecular factors have crucial roles in human metabolism and homeostasis, but the upregulation of these factors causes severe diseases such as myocarditis, prostate cancer, and other endocrine-related cancers. (bmrat.org)
  • Its potency to preferentially infect and kill cancer cells has been proven for many years and advanced clinical trials are ongoing to evaluate this virus in human [ 1 ]. (oncotarget.com)
  • Long non-coding RNAs (lncRNAs) have moved into the focus of cancer research as good candidates for tumor biomarkers and as regulators of various neoplastic cell properties. (biomedcentral.com)
  • Cancer Epidemiol cel -lines. (who.int)
  • 99:209 -215.doi:10.1007/s11060 - 010 - 0129 -5 cell carcinoma-a population-based study in with and without cervical cancer in Tbilisi, Georgia. (who.int)
  • Immediately posterior and inferior to urinary bladder are anterior part of cervix. (cytojournal.com)
  • Tissue culture commonly refers to the culture of animal cells and tissues, with the more specific term plant tissue culture being used for plants. (wikipedia.org)
  • [12] He suggested that the potentialities of individual cells via tissue culture as well as that the reciprocal influences of tissues on one another could be determined by this method. (wikipedia.org)
  • Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. (wikipedia.org)
  • After the cells of interest have been isolated from living tissue , they can subsequently be maintained under carefully controlled conditions. (wikipedia.org)
  • In practice, the term "cell culture" now refers to the culturing of cells derived from multicellular eukaryotes , especially animal cells, in contrast with other types of culture that also grow cells, such as plant tissue culture , fungal culture, and microbiological culture (of microbes ). (wikipedia.org)
  • The historical development and methods of cell culture are closely interrelated to those of tissue culture and organ culture . (wikipedia.org)
  • The laboratory technique of maintaining live cell lines (a population of cells descended from a single cell and containing the same genetic makeup) separated from their original tissue source became more robust in the middle 20th century. (wikipedia.org)
  • Since Haberlandt's original assertions, methods for tissue and cell culture have been realized, leading to significant discoveries in biology and medicine. (wikipedia.org)
  • IHC-P: Human testis tissue. (abcam.com)
  • human fetal lung, mouse embryo, mouse lung and rat lung tissue lysates. (abcam.com)
  • Such treatment was associated with upregulation of invasion- and inflammation-promoting soluble factors, such as matrix metalloproteinase 2 (MMP2), its activator MMP14, tissue inhibitors of matrix metalloproteinase 2 (TIMP2), chemokine ligand 2 (CCL2), and urokinase-type plasminogen activator (uPA), the latter two being linked to the recruitment of the monocytic cells. (biomedcentral.com)
  • Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. (lookformedical.com)
  • Viral culture is also related, with cells as hosts for the viruses. (wikipedia.org)
  • Growing viruses in cell cultures allowed preparation of purified viruses for the manufacture of vaccines . (wikipedia.org)
  • 11 Transforming viruses with dual genomes. (crsociety.org)
  • 22. Expression of the control elements of BK and SV40 viruses in human cells exhibiting different transformed phenotypes. (crsociety.org)
  • The ability of the host to trigger apoptosis in infected cells is perhaps the most powerful tool by which viruses can be cleared from the host organism. (mdpi.com)
  • To avoid elimination by this mechanism, human papillomaviruses (HPV) have developed several mechanisms that enable the cells they infect to elude both extrinsic and intrinsic apoptosis. (mdpi.com)
  • In this manuscript, we review the current literature regarding how HPV-infected cells avoid apoptosis and the molecular mechanisms involved in these events. (mdpi.com)
  • These potent effects are driven by curcumin's ability to induce G2/M cell cycle arrest, induce autophagy, activate apoptosis, disrupt molecular signaling, inhibit invasion and metastasis, and increase the efficacy of current chemotherapeutics. (hindawi.com)
  • This vaccine was made possible by the cell culture research of John Franklin Enders , Thomas Huckle Weller , and Frederick Chapman Robbins , who were awarded a Nobel Prize for their discovery of a method of growing the virus in monkey kidney cell cultures. (wikipedia.org)
  • 18. Transformation of primary human embryonic kidney cells to anchorage independence by a combination of BK virus DNA and the Harvey-ras oncogene. (crsociety.org)
  • Bosutinib has the potency to induce deep and fast responses in second- and third-/fourth-line treatment, and as a consequence, the drug has recently been licensed for patients previously treated with one or more tyrosine kinase inhibitor(s) and for whom imatinib, nilotinib, and dasatinib are not considered appropriate treatment options. (mdm2-receptor.com)
  • In the context of mCRC, CAR-T cells as monotherapy or in combination with cytokines such as IL-12 had encouraging effects such as tumor reduction and long-term disease Vanin-1-IN-1 stability in some Vanin-1-IN-1 patients (222C225). (azd1152.com)
  • Such "sprinting" flight depends on anaerobic respiration in the white cells of breast and wing muscle. (psychosocialsomatic.com)
  • Nonetheless, many other viral infections can affect the oral cavity in humans, either as localized or systemic infections. (medscape.com)
  • 7. Transformation of rodent cells by RFV, the human papovavirus with dual genome. (crsociety.org)
  • efficient and reliable establishment of lymphoblastoid cell lines by epstein-barr virus transformation from a limited amount of peripheral blood. (liverpool.ac.uk)
  • 6. Arrangement of the genome of the human papovavirus RF virus. (crsociety.org)
  • 8. Genome analysis of MG virus, a human papovavirus. (crsociety.org)
  • Cell viability indicated that tumor cell lines were differentially susceptible to each virus. (oncotarget.com)
  • Unexpectedly, up- or downregulation of CASC9 expression in HNSCC cell lines with low or high CASC9 expression, respectively, did not result in significant changes of cell viability, clonogenicity, migration or chemosensitivity. (biomedcentral.com)
  • CAR-T cells are impartial of MHCs, and due to transporting costimulatory domains, they could induce strong antitumor responses (2). (azd1152.com)
  • Sesti G, Federici M, Hribal ML, Lauro D, Sbraccia P and Lauro R (2001) Defects of the insulin receptor substrate (IRS) system in human metabolic disorders. (scielo.br)
  • HSP 84 and HSP 86, which may be subject to estrogenic regulation, have been found as components of the non-DNA binding form of mouse glucocorticoid receptor, but dissociated from the transformed DNA-binding form. (abcam.cn)
  • MA5-14485 targets Epidermal Growth Factor Receptor in IHC (P) applications and shows reactivity with Human samples. (thermofisher.com)
  • EGFR (Epidermal growth factor receptor, HER1, ErbB1) is encoded by the EGFR gene located on chromosome 7 in humans. (thermofisher.com)
  • EGFR is a transmembrane receptor and binding of its cognate ligands such as EGF (Epidermal Growth Factor) and TGF alpha (Transforming Growth Factor alpha) to the extracellular domain leads to EGFR dimerization followed by autophosphorylation of the tyrosine residues in the cytoplasmic domain. (thermofisher.com)
  • Hypoxia stimulates hypoxia inducible factor (HIF)-dependent expression of CXCL12 and KITL promoting mobilization from the bone marrow and recruitment to primary tumor and metastatic sites of CXCR4 + CD11b + bone marrow-derived cells and KITbCD11b + cells assisting vasculogenesis and metastasis respectively (Kuonen et al. (biomedcentral.com)
  • Investigation of plaque formation in chick embryo cells as a biological marker for distinguishing herpes virus type 2 from type 1. (microbiologyresearch.org)
  • Lactic acid fermentation is the type of anaerobic respiration carried out by yogurt bacteria (Lactobacillus and others) and by your own muscle cells when you work them hard and fast. (psychosocialsomatic.com)
  • Lactobacillus bacteria use the same type of anaerobic respiration as our muscle cells. (psychosocialsomatic.com)
  • Human papillomavirus type 18 (HPV18). (cellosaurus.org)
  • x-linked lymphoproliferative disease type i (xlp i) is caused by mutations in the sh2d1a gene and characterized mainly by hypogammaglobulinemia and abnormal response to epstein-barr virus with a high predisposition to b-cell non-hodgkin lymphoma development. (liverpool.ac.uk)
  • Importantly, many lncRNAs are expressed in a cell type-specific manner and their expression changes during tumorigenesis. (biomedcentral.com)
  • In 1907 the zoologist Ross Granville Harrison demonstrated the growth of frog embryonic cells that would give rise to nerve cells in a medium of clotted lymph . (wikipedia.org)
  • Altered expression of this gene has been observed in multiple human cancers. (cancerindex.org)